Assistance to twins at risk of congenital COVID-19 infection, experience report

Authors

DOI:

https://doi.org/10.33448/rsd-v9i11.10230

Keywords:

SARS-CoV-2; Congenital infection; Newborns.

Abstract

This study aimed to describe the assistance and characterize the clinical evolution of premature twins at risk of congenital infection, born to a mother infected with SARS-CoV-2 and with a clinical picture of COVID-19. It is an experience report described from the medical records of the twins and their mother. Premature twins, gestational age 28 weeks and three days, both male. The twin I weighed 1050 grams and the second, 698 grams. At 36h of life, collection was performed by means of swab of oro and nasopharynx, of both, for RT-PCR research for SARS-CoV-2, positive in both. Twin I died after 48 hours of life and II stayed in the Neonatal Intensive Care Unit for more than 2 months. There was no contact of the mother with the twins at the moment of birth until the fifteenth day of life of the twin II, there was also no breastfeeding during this period. New RT-PCR research for SARS-CoV-2 and rapid test performed on the fifteenth day of life were negative. The possibility of mother-to-child transmission and the consequences that this virus can cause on the fetus is worrying. However, there are several reports that suggest a low potential for this transmission, yet this possibility cannot be ruled out and must be ensured by adequate assistance with trained staff and all transmission care taken after birth.

References

Chen, H., Guo, J., Wang, C., Luo, F., Yu, X., Zhang, W., Li, J., Zhao, D., Xu, D., Gong, Q., Liao, J., Yang, H., Hou, W., & Zhang, Y. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet (London, England), 395(10226), 809–815.

Hong, H., Wang, Y., Chung, H. T., & Chen, C. J. (2020). Clinical characteristics of novel coronavirus disease 2019 (COVID-19) in newborns, infants and children. Pediatrics and neonatology, 61(2), 131–132.

Hsu, A. L., Guan, M., Johannesen, E., Stephens A. J., Khaleel, N., Kagan, N., Tuhlei, B. C., & Wan, X. F. (2020). Placental SARS-CoV-2 in a patient with mild COVID-19 disease. Journal of Medical Virology, 2020, 1-7.

Juan, J., Gil, M. M., Rong, Z., Zhang, Y., Yang, H., & Poon, L. C. (2020). Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound in obstetrics & gynecology: the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 56(1), 15–27.

Köche, J. C. (2011). Fundamentos de metodologia cinetídica: teoria da ciência e iniciação à pesquisa. Petrópolis, RJ: Vozes, 185p.

Kotlyar, A. M., Grechukhina, O., Chen, A., Popkhadze, S., Grimshaw, A., Tal, O., Taylor, H. S., & Tal, R. (2020). Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis. American journal of obstetrics and gynecology, S0002-9378(20)30823-1.

Ludke, M., & Andre, M. E. D. A. (2013). Pesquisas em educação: uma abordagem qualitativa (2a ed.). São Paulo: E.P.U.

Ma, X., Zhu, J., & Du, L. (2020). Neonatal management during the Coronavirus Disease (COVID-19) outbreak: the chinese experience. Neoreviews, 21(5), 293-297.

Muhidin, S., Behboodi Moghadam, Z., & Vizheh, M. (2020). Analysis of maternal coronavirus infections and neonates born to mothers with 2019-nCoV; a Systematic Review. Archives of academic emergency medicine, 8(1), e49.

Penfield, C. A., Brubaker, S. G., Limaye, M. A., Lighter, J., Ratner, A. J., Thomas, K. M., Meyer, J. A., & Roman, A. S. (2020). Detection of severe acute respiratory syndrome coronavirus 2 in placental and fetal membrane samples. American journal of obstetrics & gynecology MFM, 2(3), 100133.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica. Santa Maria, RS: UFSM, NTE, 119p.

Vivanti, A. J., Vauloup-Fellous, C., Prevot, S., Zupan, V., Suffee, C., Do Cao, J., Benachi, A., & De Luca, D. (2020). Transplacental transmission of SARS-CoV-2 infection. Nature communications, 11(1), 3572.

Yin, R. K. (2015). O estudo de caso: planejamentos e métodos (5a ed.) Porto Alegre: Bookman.

Zhu, H., Wang, L., Fang, C., Peng, S., Zhang, L., Chang, G., Xia, S., & Zhou, W. (2020). Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Translational pediatrics, 9(1), 51–60.

Published

02/12/2020

How to Cite

MOREIRA, I. F. .; TENÓRIO, J. L. .; MOREIRA, R. T. de F. .; CALUMBY, R. J. N. .; LIMA, C. M. F. de .; SOUSA, E. C. A. de . Assistance to twins at risk of congenital COVID-19 infection, experience report. Research, Society and Development, [S. l.], v. 9, n. 11, p. e75191110230, 2020. DOI: 10.33448/rsd-v9i11.10230. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/10230. Acesso em: 19 apr. 2024.

Issue

Section

Health Sciences