Hyperthrophic cardiomyopathy associated with a non-compaction left ventricle: a case report





Hypertrophic cardiomyopathy; Left ventricular noncompaction.


Objective: Report the concomitance of two cardiomyopathies: Hypertrophic cardiomyopathy and Left ventricular noncompaction on a 27 years old patient. Method: Literature research and comparison with the case report. Results: Hypertrophic cardiomyopahty is the most common genetic cardiac disease, instead of Left ventricular noncompaction, that is a rare genetic cardiac disease. The evaluation of the reported case showed the presence of those two diseases, simultaneously. Conclusions: It is important to look at the fact that the patient showed only difficult breathing to medium and great efforts; but was diagnosed a rare disease in the concomitance of another cardiomyopathy; the treatment chosen was the implantation of a implant cardioverter defibrillator, because of it’s indication on the two diseases.


Ammirati, E., Contri, R., Coppini, R., Cecchi, F., Frigerio, M., & Olivotto, I. (2016). Pharmacological treatment of hypertrophic cardiomyopathy: current practice and novel perspectives. European journal of heart failure, 18(9), 1106-1118. https://doi.org/10.1002/ejhf.541

Attenhofer-Jost, C. H., & Connolly, H. M. (2016). Isolated left ventricular noncompaction in adults: Clinical manifestations and diagnosis. UpToDate. Retrieved April 30, 2019, from https://www.uptodate.com/contents/isolated-left-ventricular-noncompaction-in-adults-clinical-manifestations-and-diagnosis

Bittencourt, M. I., Rocha, R. M., & Filho, F. M. A. (2010). Cardiomiopatia Hipertrófica. Revista Brasileira de Cardiologia, 23(1), 17-24. http://sociedades.cardiol.br/socerj/revista/2010_01/a2010_v23_n01_01bitencourt.pdf

Cao, Y., & Zhang, P. (2017). Review of recent advances in the management of hypertrophic cardiomyopathy. European review for medical and pharmacological sciences, 21(22), 5207-5210. https://doi.org/10.26355/eurrev_201711_13841

Enriquez, A. D., & Goldman, M. E. (2014). Management of hypertrophic cardiomyopathy. Annals of global health, 80(1), 35-45. https://doi.org/10.1016/j.aogh.2013.12.004

Geske, J. B., Ommen, S. R., & Gersh, B. J. (2018). Hypertrophic Cardiomyopathy: Clinical Update. JACC Heart Failure, 6(5), 364-375. https://doi.org/10.1016/j.jchf.2018.02.010

Hensley, N., Dietrich, J., Nyhan, D., Mitter, N., Yee, M., & Brady, M. (2015). Hypertrophic cardiomyopathy: a review. Anesthesia and analgesia, 120(3), 554-569. https://doi.org/10.1213/ANE.0000000000000538

Koche, J. C. (2011). Fundamentos de Metodologia Científica [e-book]. Petrópolis, Editora Vozes, 2002. Disponível em: http://www.brunovivas.com/wp-content/uploads/sites/10/2018/07/K%C3%B6che-Jos%C3%A9-Carlos0D0AFundamentos-de-metodologia-cient%C3%ADfica-_-teoria-da0D0Aci%C3%AAncia-e-inicia%C3%A7%C3%A3o-%C3%A0-pesquisa.pdf Acesso em: 27 dez. 2020.

Ludke, M. & Andre, M. E . D. A. (2013). Pesquisas em educação: uma abordagem qualitativa. São Paulo: E.P.U. F.

Malla, R., Sharma, R., Raunyiar, B., Kc, M. B., Maskey, A., Joshi, D., & Hamal, S. (2009). Left ventricular noncompaction. JNMA; Journal of the Nepal Medical Association, 48(174), 180-184. https://pubmed.ncbi.nlm.nih.gov/20387366/

Maron, B. J. (2002). Hypertrophic Cardiomyopathy: A Systematic Review. JAMA, 287(10), 1308-1320. https://jamanetwork.com/journals/jama/fullarticle/194713

Maron, B. J., Gardin, J. M., Flack, J. M., Gidding, S. S., Kurosaki, T. T., & Bild, D. E. (1995). Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults. Circulation, 92(4), 785-789. https://doi.org/10.1161/01.cir.92.4.785

Maron, M. S. (2019). Hypertrophic cardiomyopathy: Clinical manifestations, diagnosis, and evaluation. UpToDate. Retrieved April 27, 2019, from https://www.uptodate.com/contents/hypertrophic-cardiomyopathy-clinical-manifestations-diagnosis-and-evaluation

Moric-Janiszewska, E., & Markiewicz-Łoskot, G. (2008). Genetic heterogeneity of left-ventricular noncompaction cardiomyopathy. Clinical cardiology, 31(5), 201-204. https://doi.org/10.1002/clc.20202

Pereira, A. S. et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed.UAB/NTE/UFSM. Disponível em: https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1. Acesso em: 27 dez. 2020.

Rooms, I., Dujardin, K., & De Sutter, J. (2015). Non-compaction cardiomyopathy: a genetically and clinically heterogeneous disorder. Acta Cardiologica, 70(6), 625-631. https://doi.org/10.2143/AC.70.6.3120173

Ritter, M., Oechslin, E., Sütsch, G., Attenhofer, C., Schneider, J., & Jenni, R. (1997). Isolated noncompaction of the myocardium in adults. Mayo Clinic proceedings, 72(1), 26-31. https://doi.org/10.4065/72.1.26

Zaragoza, M. V., Arbustini, E., & Narula, J. (2007). Noncompaction of the left ventricle: primary cardiomyopathy with an elusive genetic etiology. Current opinion in pediatrics, 19(6), 619–627. https://doi.org/10.1097/MOP.0b013e3282f1ecbc



How to Cite

MROGINSKI, L. S. C. .; SCALABRIN, R. .; MEDEIROS, P. H. K. B. .; BELLINASO, M.; BAMBERG, F. W. .; MACHADO, R. D.; PORTELLA, N. R. da C. .; TAGLIETTI, Z. R. Hyperthrophic cardiomyopathy associated with a non-compaction left ventricle: a case report. Research, Society and Development, [S. l.], v. 10, n. 1, p. e8910111500, 2021. DOI: 10.33448/rsd-v10i1.11500. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/11500. Acesso em: 2 feb. 2023.



Health Sciences