Influence of gamma irradiation on the restorative interface and surface morphology of bulk fill dental composites




Gamma Rays; Radiotherapy Dosage; Dental Materials; Evidence-based dentistry.


Objective: The purpose in this in vitro study was to evaluate the influence of gamma irradiation on the marginal integrity and surface morphology of bulk fill resin composites by Microcomputed tomography (μ-CT) and Scanning Electron Microscopy (SEM). Methods: class I cavities (3 mm deep) were prepared in 60 third molars restored with the following resin composites: Filtek™ Bulk Fill (FBF), TetricEvoCeram Bulk Fill (TBF), X-tra Fil Bulk Fill (XTA) and Filtek™ Z350 (Z350) (n = 15). The samples were immersed in 50% silver nitrate solution, scanned and subdivided according to the gamma radiation doses (Control group – no radiation, 30 and 60 Gy). After irradiation, the teeth were again immersed in silver nitrate and scanned. For morphological analysis, 12 cylindrical (10 x 2mm) specimens were and submitted to the studied radiation regimens (n =4). Data were analyzed by the Kruskal-Wallis and Fisher LSD tests (α = 0.05). Results: it was observed that the irradiation negatively affected the marginal integrity of samples restored with FBF (p < 0.05). No significant differences were observed for the other resin composites. No changes were shown in the surface morphology of bulk fill composites, despite irradiation having affected the surface morphology of the control group (Z350). It was concluded that the accumulated doses of 30 and 60 Gy negatively affected the tooth-restoration interface of FBF and at the surface morphology of Z350. Conclusions: TetricEvoCeram, and X-tra Fil Bulk Fill resin composites can be considered alternatives in the restorative treatment of patients submitted to radiotherapy of the head and neck.


Almeida Durão, M., de Andrade, A. K. M., da Silva, M. D. C. M., Montes, M. A. J. R., & de Melo Monteiro, G. Q. (2020). Clinical Performance of Bulk-Fill Resin Composite Restorations Using the United States Public Health Service and Federation Dentaire Internationale Criteria: A 12-Month Randomized Clinical Trial. European Journal of Dentistry.

Adi, A., & Altinawi, M. K. (2020). Marginal microleakage evaluation of class II bulk-fill composite restorations in primary molars–in vitro study. Journal of Stomatology, 73(2), 74-80.

Arbildo-Vega, H. I., Lapinska, B., Panda, S., Lamas-Lara, C., Khan, A. S., & Lukomska-Szymanska, M. (2020). Clinical effectiveness of bulk-fill and conventional resin composite restorations: Systematic review and meta-analysis. Polymers, 12(8), 1786.

Amade, E. S., Ferreira, F. M., Novais, V. R., Correr-Sobrinho, L., & Soares, C. J. (2010). Influência da radiação nas propriedades de diferentes materiais resinosos. Revista Odontológica do Brasil Central, 19(50).

Benetti, A. R., Havndrup-Pedersen, C., Honoré, D., Pedersen, M. K., & Pallesen, U. (2015). Bulk fill resin composites: polymerization contraction, depth of cure, and gap formation. Operative dentistry, 40(2), 190-200.

Berti, L. S., Turssi, C. P., Amaral, F. L., Basting, R. T., Junqueira, J. L. C., Panzarella, F. K., ... & França, F. M. (2020). Clinical and radiographic evaluation of high viscosity bulk-fill resin composite restorations. Am J Dent, 33(4), 213-217.

Bucuta, S., & Ilie, N. (2014). Light transmittance and micro-mechanical properties of bulk fill vs. conventional resin based composites. Clinical oral investigations, 18(8), 1991-2000.

Campos, L. M. P., Boaro, L. C., Santos, L. K. G., Parra, D. F., & Lugao, A. B. (2015). Influence of ionizing radiation on the mechanical properties of BisGMA/TEGDMA based experimental resin. Radiation Physics and Chemistry, 115, 30-35.

Carrera, C. A., Lan, C., Escobar-Sanabria, D., Li, Y., Rudney, J., Aparicio, C., & Fok, A. (2015). The use of micro-CT with image segmentation to quantify leakage in dental restorations. Dental Materials, 31(4), 382-390.

Catelan, A., Padilha, A. C., Salzedas, L. M., Coclete, G. A., & dos Santos, P. H. (2008). Effect of radiotherapy on the radiopacity and flexural strength of a composite resin. Acta Odontol Latinoam, 21(2), 159-62.

Cruz, A. D., Almeida, S. M., Rastelli, A. N. S., Bagnato, V. S., & Byscolo, F. N. (2009). FT-IR spectroscopy assessment of aesthetic dental materials irradiated with low-dose therapeutic ionizing radiation. Laser physics, 19(3), 461-467.

Cruz, A. D. D., Cogo, K., Bergamaschi, C. D. C., Bóscolo, F. N., Groppo, F. C., & Almeida, S. M. D. (2010). Oral Streptococci growth on aging and non-aging esthetic restorations after radiotherapy. Brazilian dental journal, 21(4), 346-350.

Elmarakby, A. M. (2020). One Bulk Fill Composite Restorative Material: Advantages and Application Technique. EC Dental Science, 19.

Ersen, K. A., Gürbüz, Ö., & Özcan, M. (2020). Evaluation of polymerization shrinkage of bulk-fill resin composites using microcomputed tomography. Clinical oral investigations, 24(5), 1687-1693.

Fronza, B. M., Rueggeberg, F. A., Braga, R. R., Mogilevych, B., Soares, L. E. S., Martin, A. A., & Giannini, M. (2015). Monomer conversion, microhardness, internal marginal adaptation, and shrinkage stress of bulk fill resin composites. Dental materials, 31(12), 1542-1551.

Furness, A., Tadros, M. Y., Looney, S. W., & Rueggeberg, F. A. (2014). Effect of bulk/incremental fill on internal gap formation of bulk fill composites. Journal of dentistry, 42(4), 439-449.

Ilie, N., Bucuta, S., & Draenert, M. (2013). Bulk fill resin-based composites: an in vitro assessment of their mechanical performance. Operative dentistry, 38(6), 618-625.

Jacker-Guhr, S., Ibarra, G., Oppermann, L. S., Lührs, A. K., Rahman, A., & Geurtsen, W. (2016). Evaluation of microleakage in class V composite restorations using dye penetration and micro-CT. Clinical oral investigations, 20(7), 1709-1718.

Kalmowicz, J., Phebus, J. G., Owens, B. M., Johnson, W. W., & King, G. T. (2015). Microleakage of class I and II composite resin restorations using a sonic-resin placement system. Operative dentistry, 40(6), 653-661.

Köche, J. C. (2016). Fundamentos de metodologia científica. Editora Vozes.

Landis, J. R., & Koch, G. G. (1977). The measurement of observer agreement for categorical data. biometrics, 159-174.

Lima, R. B. W. E., De Vasconcelos, L. C., Pontual, M. L., Meireles, S. S., Andrade, A. K. M., & Duarte, R. M. (2019). Effect of ionizing radiation on the properties of restorative materials. Indian Journal of Dental Research, 30(3), 408.

Orłowski, M., Tarczydło, B., & Chałas, R. (2015). Evaluation of marginal integrity of four bulk fill dental composite materials: in vitro study. The Scientific World Journal, 2015.

Naves, L. Z., Novais, V. R., Armstrong, S. R., Correr-Sobrinho, L., & Soares, C. J. (2012). Effect of gamma radiation on bonding to human enamel and dentin. Supportive Care in Cancer, 20(11), 2873-2878.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica.

Reed, R., Xu, C., Liu, Y., Gorski, J. P., Wang, Y., & Walker, M. P. (2015). Radiotherapy effect on nano-mechanical properties and chemical composition of enamel and dentine. Archives of oral biology, 60(5), 690-697.

Rengo, C., Spagnuolo, G., Ametrano, G., Goracci, C., Nappo, A., Rengo, S., & Ferrari, M. (2015). Marginal leakage of bulk fill composites in Class II restorations: a microCT and digital microscope analysis. International Journal of Adhesion and Adhesives, 60, 123-129.

Swain, M. V., & Xue, J. (2009). State of the art of Micro‐CT applications in dental research. International journal of oral science, 1(4), 177-188.

Tekin, T. H., Figen, A. K., Atalı, P. Y., Filiz, B. C., & Pişkin, M. B. (2017). Full in-vitro analyses of new-generation bulk fill dental composites cured by halogen light. Materials Science and Engineering: C, 77, 436-445.

Tekçe, N., Pala, K., Demirci, M., & Tuncer, S. (2016). Changes in surface characteristics of two different resin composites after 1 year water storage: An SEM and AFM study. Scanning, 38(6), 694-700.

Tomaszewska, I. M., Kearns, J. O., Ilie, N., & Fleming, G. J. (2015). Bulk fill restoratives: To cap or not to cap–That is the question?. Journal of dentistry, 43(3), 309-316.

Troconis, C. C. M., Santos-Silva, A. R., Brandao, T. B., Lopes, M. A., & de Goes, M. F. (2017). Impact of head and neck radiotherapy on the mechanical behavior of composite resins and adhesive systems: A systematic review. Dental Materials, 33(11), 1229-1243.

Veloso, S. R. M., Lemos, C. A. A., de Moraes, S. L. D., do Egito Vasconcelos, B. C., Pellizzer, E. P., & de Melo Monteiro, G. Q. (2019). Clinical performance of bulk fill and conventional resin composite restorations in posterior teeth: a systematic review and meta-analysis. Clinical oral investigations, 23(1), 221-233.




How to Cite

VASCONCELOS, L. C. de .; MONTEIRO, G. Q. de M.; PONTUAL, A. dos A.; RAMOS-PEREZ, F. M. de M.; OLIVEIRA, J. de A.; PEREZ, D. E. da C.; PONTUAL, M. L. dos A. Influence of gamma irradiation on the restorative interface and surface morphology of bulk fill dental composites . Research, Society and Development, [S. l.], v. 10, n. 4, p. e53910414348, 2021. DOI: 10.33448/rsd-v10i4.14348. Disponível em: Acesso em: 29 jan. 2023.



Health Sciences