Prevalence of cerebral palsy in neonates of mothers affected by Zika virus: An integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i7.16335

Keywords:

Infant; Newborn; Zika virus infection; Cerebral palsy.

Abstract

Abstract

Objective: To determine, from an integrative literature review, the prevalence of cerebral palsy in neonates with mothers affected by Zika virus in Brazil. Methodology: Full articles from the Medical Publications (PubMed) and Latin American and Caribbean Literature in Health Sciences (LILACS) databases were used. For the search, the descriptors were used: Infection by Zika virus, Zika virus, newborn and cerebral palsy; obtained according to the Health Sciences Descriptors (DeCS), with the Boolean operator “E / AND”. After applying the inclusion criteria defined above, nine articles were selected for review. Results: Regarding the place where the study was carried out, 77.78% were carried out in the Northeast region of the country. One of the studies had a sample of 538 individuals. The prevalence of cerebral palsy associated with congenital Zika virus infection ranged from 15.2% to 100%. Conclusion: It is concluded that there is a high prevalence of cases of neonates of mothers affected by ZIKV with cerebral palsy. These data reinforce the need for early intervention services and resource planning to support these families in healthcare and community settings in Brazil.

Keywords: Infant; Newborn; Zika virus infection; Cerebral palsy.

References

Barjas‐Castro, M. L., Angerami, R. N., Cunha, M. S., Suzuki, A., Nogueira, J. S., Rocco, I. M., ... & Addas‐Carvalho, M. (2016). Probable transfusion‐transmitted Zika virus in Brazil. Transfusion, 56(7), 1684-1688.

Besnard, M., Lastere, S., Teissier, A., Cao-Lormeau, V. M., & Musso, D. (2014). Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014. Eurosurveillance, 19(13), 20751.

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde (2018). Monitoramento integrado de alterações no crescimento e desenvolvimento relacionadas à infecção pelo vírus Zika e outras etiologias infecciosas, até a Semana Epidemiológica 48 de 2017. 49, 1–10. https://portalarquivos2.saude.gov.br/images/pdf/2018/janeiro/30/2018-002.pdf.

Brasil, P., Pereira Jr, J. P., Moreira, M. E., Ribeiro Nogueira, R. M., Damasceno, L., Wakimoto, M., ... & Nielsen-Saines, K. (2016). Zika virus infection in pregnant women in Rio de Janeiro. New England Journal of Medicine, 375(24), 2321-2334.

Brunoni, D., Blascovi-Assis, S. M., Osório, A. A. C., Seabra, A. G., Amato, C. A. D. L. H., Teixeira, M. C. T. V., ... & Carreiro, L. R. R. (2016). Microcefalia e outras manifestações relacionadas ao vírus Zika: impacto nas crianças, nas famílias e nas equipes de saúde. Ciência & Saúde Coletiva, 21, 3297-3302.

Campos, G. S., Bandeira, A. C., & Sardi, S. I. (2015). Zika virus outbreak, bahia, brazil. Emerging infectious diseases, 21(10), 1885.

Cao-Lormeau, V. M., Blake, A., Mons, S., Lastère, S., Roche, C., Vanhomwegen, J., ... & Ghawché, F. (2016). Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. The Lancet, 387(10027), 1531-1539.

Carteaux, G., Maquart, M., Bedet, A., Contou, D., Brugières, P., Fourati, S., ... & Mekontso Dessap, A. (2016). Zika virus associated with meningoencephalitis. New England Journal of Medicine, 374(16), 1595-1596.

Carvalho, A., Brites, C., Mochida, G., Ventura, P., Fernandes, A., Lage, M. L., ... & Lucena, R. (2019). Clinical and neurodevelopmental features in children with cerebral palsy and probable congenital Zika. Brain and Development, 41(7), 587-594.

Carvalho, A. L. D., Ventura, P., Taguchi, T., Brandi, I., Brites, C., & Lucena, R. (2020a). Cerebral palsy in children with congenital Zika syndrome: a 2-year neurodevelopmental follow-up. Journal of child neurology, 35(3), 202-207.

Carvalho, A., Sales, H. F., Ventura, P., Gnoatto‐Medeiros, M., Brites, C., & Lucena, R. (2020b). The neurodevelopmental spectrum of congenital Zika infection: a scoping review. Developmental Medicine & Child Neurology, 62(12), 1356-1362.

Carvalho, A. L. (2020) Cerebral palsy in children with congenital zika syndrome: a 2-year neurodevelopmental follow-up. Journal of Child Neurology,35(3),202-207.

Duarte, R. S., Almeida, B. L. F., Sousa, M. N. A., Rolim, L. A. D. M. M. & Jucá Júnior, F. T. V.(2018) Sequelas da febre Chikungunya e sua interferência na qualidade de vida de indivíduos. Revista Brasileira de Qualidade de Vida (RBQV), 10, 1-14.

Duffy, M. R., Chen, T. H., Hancock, W. T., Powers, A. M., Kool, J. L., Lanciotti, R. S., ... & Hayes, E. B. (2009). Zika virus outbreak on Yap Island, federated states of Micronesia. New England Journal of Medicine, 360(24), 2536-2543

.

Einspieler, C., Utsch, F., Brasil, P., Aizawa, C. Y. P., Peyton, C., Hasue, R. H., ... & GM Zika Working Group. (2019). Association of infants exposed to prenatal Zika virus infection with their clinical, neurologic, and developmental status evaluated via the general movement assessment tool. JAMA network open, 2(1), e187235-e187235.

Fauci, A. S., & Morens, D. M. (2016). Zika virus in the Americas—yet another arbovirus threat. New England journal of medicine, 374(7), 601-604.

Ferreira, H. N. C., Schiariti, V., Regalado, I. C. R., Sousa, K. G., Pereira, S. A., Fechine, C. P. N. D. S., & Longo, E. (2018). Functioning and disability profile of children with microcephaly associated with congenital Zika virus infection. International journal of environmental research and public health, 15(6), 1107.

Furtado, J. M., Espósito, D. L., Klein, T. M., Teixeira-Pinto, T., & da Fonseca, B. A. (2016). Uveitis associated with Zika virus infection. New England Journal of Medicine, 375(4), 394-396.

Hills, S. L., Fischer, M., & Petersen, L. R. (2017). Epidemiology of Zika virus infection. The Journal of infectious diseases, 216(suppl_10), S868-S874.

Javanian, M., Masrour-Roudsari, J., & Ebrahimpour, S. Clinical diagnosis challenges in Zika virus infection. Caspian J Intern Med 2018; 9 (4): 416-417. Mostafa Javanian (MD), 1.

Lopes, M. H., Miyaji, K. T., & Infante, V. (2016). Zika virus. Revista da Associação Médica Brasileira, 62(1), 4-9.

Macnamara, F. N. (1954). Zika virus: a report on three cases of human infection during an epidemic of jaundice in Nigeria. Transactions of the royal society of tropical medicine and hygiene, 48(2), 139-145.

Marques, F. J., Teixeira, M. C., Barra, R. R., de Lima, F. M., Dias, B. L. S., Pupe, C., ... & Leyser, M. (2019). Children born with congenital Zika syndrome display atypical gross motor development and a higher risk for cerebral palsy. Journal of child neurology, 34(2), 81-85.

Mécharles, S., Herrmann, C., Poullain, P., Tran, T. H., Deschamps, N., Mathon, G., ... & Lannuzel, A. (2016). Acute myelitis due to Zika virus infection. The Lancet, 387(10026), 1481.

Mehrjardi, M. Z., Poretti, A., Huisman, T. A., Werner, H., Keshavarz, E., & Júnior, E. A. (2017). Neuroimaging findings of congenital Zika virus infection: a pictorial essay. Japanese journal of radiology, 35(3), 89-94.

Melo, A., Gama, G. L., Da Silva Júnior, R. A., De Assunção, P. L., Tavares, J. S., Da Silva, M. B., ... & De Amorim, M. M. (2020). Motor function in children with congenital Zika syndrome. Developmental Medicine & Child Neurology, 62(2), 221-226.

Melo, A. S. O., Malinger, G., Ximenes, R., Szejnfeld, P. O., Alves Sampaio, S., & Bispo de Filippis, A. M. (2016a). Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg?. Ultrasound in Obstetrics & Gynecology, 47(1), 6-7.

Melo, A. S., Aguiar, R., Amorim, M. M., Arruda, M., de Melo, F., Ribeiro, S. T., ... & Tanuri, A. (2016b). Congenital Zika Virus Infection: Beyond Neonatal Microcephaly. Jama Neurology, 73(12), 1407-1416.

Menezes, E. D. C., Santos, F. A. H., & Alves, F. L. (2017). Cerebral palsy dysphagia: a systematic review. Revista CEFAC, 19(4), 565-574.

Mlakar, J., Korva, M., Tul, N., Popović, M., Poljšak-Prijatelj, M., Mraz, J., ... & Avšič Županc, T. (2016). Zika virus associated with microcephaly. New England Journal of Medicine, 374(10), 951-958.

Moore, C. A., Staples, J. E., Dobyns, W. B., Pessoa, A., Ventura, C. V., Da Fonseca, E. B., ... & Rasmussen, S. A. (2017). Characterizing the pattern of anomalies in congenital Zika syndrome for pediatric clinicians. JAMA pediatrics, 171(3), 288-295.

Mowbray, P. K., Wilkinson, A., & Tse, H. H. (2015). An integrative review of employee voice: Identifying a common conceptualization and research agenda. International Journal of Management Reviews, 17(3), 382-400.

Pan American Health Organization (2017). Zika—epidemiological report Brazil. 2017. Washington, DC: PAHO/WHO, 2017

http://www2.paho.org/hq/index.php?option=com_docman&task=doc_view&gid=35221&&Itemid=270.

Pereira, A. M., Araújo Júnior, E., Werner, H., & Monteiro, D. L. M. (2020). Zika virus and pregnancy: association between acute infection and microcephaly in newborns in the state of Rio de Janeiro, Brazil. Geburtshilfe und Frauenheilkunde, 80(1), 60.

Pereira, L. P., de Almeida, A. O. L. C., de Jesus Lima, C. C. O., Santos, J. B., dos Santos Barbosa, M., & Felzemburgh, R. D. M. (2019). Seizures in newborn with microcephaly associated to Zika virus infection/Crises convulsivas em neonato com microcefalia associada a infeccao pelo Zika virus/Crisis convulsivas en neonato con microcefalia asociada a la infeccion por el virus de Zika. Enfermagem Uerj, 27, NA-NA.

Pessoa, A., van der Linden, V., Yeargin-Allsopp, M., Carvalho, M. D. C. G., Ribeiro, E. M., Braun, K. V. N., ... & Moore, C. A. (2018). Motor abnormalities and epilepsy in infants and children with evidence of congenital Zika virus infection. Pediatrics, 141(Supplement 2), S167-S179.

Rozé, B., Najioullah, F., Signate, A., Apetse, K., Brouste, Y., Gourgoudou, S., ... & Cabié, A. (2016). Zika virus detection in cerebrospinal fluid from two patients with encephalopathy, Martinique, February 2016. Eurosurveillance, 21(16), 30205.

Russell, K., Hills, S. L., Oster, A. M., Porse, C. C., Danyluk, G., Cone, M., ... & Brooks, J. T. (2017). Male-to-female sexual transmission of Zika virus—United States, January–April 2016. Clinical Infectious Diseases, 64(2), 211-213.

Satterfield-Nash, A., Kotzky, K., Allen, J., Bertolli, J., Moore, C. A., Pereira, I. O., ... & Melo, F. (2017). Health and development at age 19–24 months of 19 children who were born with microcephaly and laboratory evidence of congenital Zika virus infection during the 2015 Zika virus outbreak—Brazil, 2017. MMWR. Morbidity and mortality weekly report, 66(49), 1347.

Sharp, T. M., Muñoz-Jordán, J., Perez-Padilla, J., Bello-Pagán, M. I., Rivera, A., Pastula, D. M., ... & Rivera-García, B. (2016). Zika virus infection associated with severe thrombocytopenia. Clinical Infectious Diseases, 63(9), 1198-1201.

Takahasi, E. H. M., Alves, M. T. S. S. B., Ribeiro, M. R. C., Souza, V. F. P., Simões, V. M. F., Borges, M. C. R. ,…, Silva, A. A. M. D. (2021). Gross motor function in children with Congenital Zika Syndrome. Neuropediatrics, 52(1), 34-43.

Ventura, P. A., Lage, M. L. C., de Carvalho, A. L., Fernandes, A. S., Taguchi, T. B., & Nascimento-Carvalho, C. M. (2020). Early gross motor development among Brazilian children with microcephaly born right after Zika virus infection outbreak. Journal of Developmental & Behavioral Pediatrics, 41(2), 134-140.

Published

14/06/2021

How to Cite

CRUZ, L. T.; OLIVEIRA FILHO, O. B. de; SOUSA, M. N. A. de . Prevalence of cerebral palsy in neonates of mothers affected by Zika virus: An integrative literature review. Research, Society and Development, [S. l.], v. 10, n. 7, p. e6910716335, 2021. DOI: 10.33448/rsd-v10i7.16335. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/16335. Acesso em: 24 apr. 2024.

Issue

Section

Health Sciences