Factors associated with hemoglobin variation in women submitted to hemodialysis





Chronic kidney disease; Anemia; Hemodialysis.


To evaluate the factors associated with the decline in hemoglobin in patients with CKD. This is a cross-sectional study, conducted with women undergoing hemodialysis, except for those with hemolytic diseases. The collection of biochemical and anthropometric data was carried out from the electronic medical records of the patients included in the research. 80% of the women were adults and the most prevalent chronic condition was Systemic Arterial Hypertension (75.65%). It was possible to verify that all the categories analyzed presented an average hemoglobin value below 12g /dL, indicating anemia as a problem in effect in the studied public. The factors that showed a statistically significant association with the lowest hemoglobin levels were: Hypertension, Diabetes mellitus and the shortest time on hemodialysis. The presence of other conditions in patients with CKD, such as diabetes, hypertension and shorter hemodialysis time, contribute to greater impairment of hemoglobin levels.

Author Biographies

Danielle Alice Vieira da Silva, Centro Universitário Tiradentes

Nutricionista. Mestre em Nutrição Humana pela Universidade Federal de Alagoas. Docente do curso de Nutrição do Centro Universitário Tiradentes.

Lidyane Cerqueira de Araujo Silva, Centro Universitário Tiradentes

Nutricionista. Graduada pelo Centro Universitário Tiradentes-UNIT/AL.

Ícaro Carlos Oliveira de Andrade, Centro Universitário Tiradentes

Acadêmico de nutrição. Centro Universitário Tiradentes, UNIT/AL.

Ayná Santos de Lima, Centro Universitário Tiradentes

Nutricionista. Graduada pelo Centro Universitário Tiradentes-UNIT/AL.

João Paulo da Silva Lima, Centro Universitário Tiradentes

. Nutricionista do Hospital Vida. Graduado pelo Centro Universitário Tiradentes-UNIT/AL.

Ana Debora Santos de Oliveira, Universidade Federal de Alagoas

Acadêmica de Nutrição. Graduanda na faculdade de Nutrição da Universidade Federal de Alagoas (UFAL)


Bragman R. (2009). Anemia na Doença Renal Crônica. Braz J. Nephrol., 31 (1 suppl 1), 36-41. https://www.bjnephrology.org/en/article/anemia-na-doenca-renal-cronica/

Bowry, S. K., & Gatti, E. (2011). Impact of Hemodialysis Therapy on Anemia of Chronic Kidney Disease: The Potential Mechanisms. Blood Purification, 32(3), 210-219. doi:10.1159/000329573

El-Achkar, T. M., Ohmit, S. E., Mccullough, P. A., Crook, E. D., Brown, W. W., Grimm, R., Flack, J. M. (2005). Higher prevalence of anemia with diabetes mellitus in moderate kidney insufficiency: The Kidney Early Evaluation Program. Kidney International, 67(4), 1483-1488. doi:10.1111/j.1523-1755.2005.00226.x

Gargiulo, R., Suhail, F., & Lerma, E. V. (2015). Hypertension and chronic kidney disease. Disease-a-Month, 61(9), 387-395. doi:10.1016/j.disamonth.2015.07.003

Hazin, M. A. (2020). Anemia in chronic kidney disease. Revista Da Associação Médica Brasileira, 66(Suppl 1). doi:10.1590/1806-9282.66.s1.55

Kruse, A., Uehlinger, D. E., Gotch, F., Kotanko, P., & Levin, N. W. (2008). Red Blood Cell Lifespan, Erythropoiesis and Hemoglobin Control. Hemodialysis - From Basic Research to Clinical Trials Contributions to Nephrology, 247-254. doi:10.1159/000130698

Maiese, K. (2015). Erythropoietin and diabetes mellitus. World Journal of Diabetes, 6(14), 1259. doi:10.4239/wjd.v6.i14.1259

Penteado, B.A.., Lima, W.F., Milagres, C.S. (2017). Etiologia de anemia em pacientes renais crônicos em tratamento hemodialítico. Rev. Cien. FHO, v. 5, n. 1, p. 18-23.

Prestes, F.C., et al (2011). Percepção dos trabalhadores de enfermagem sobre a dinâmica do trabalho e os pacientes em um serviço de hemodiálise. Text. Cont. Enferm., v. 20, n. 1, p. 25-32.

Ribeiro, W.A., Jorge B.O., Queiroz, R.S. (2020). Repercussões da hemodiálise no paciente com doença renal crônica. Revista Pró-UniverSUS, v. 11, n. 1, p. 88-97.

Rosa, K.R.., Loures, M.C. (2013). Qualidade de vida de idosos em hemodiálise. EVS, v. 40, n. 4, p. 419-446.

Santos, N.C., et al. (2020). O papel do Enfermeiro na anemia associada à doença renal crônica. Research Society and Development, v. 9, n. 8, p. 1-16.

Shaikh, H.., Aeddula, N.R. (2020). Anemia Of Chronic Renal Disease. https://www.ncbi.nlm.nih.gov/books/NBK539871/

Sociedade Brasileira de Nefrologia (2017). Tratamento Hemodialítico. https://sbn.org.br

Stauffer, M. E., & Fan, T. (2014). Prevalence of Anemia in Chronic Kidney Disease in the United States. PLoS ONE, 9(1). doi:10.1371/journal.pone.0084943

Symeonidis, A., Kouraklis-Symeonidis, A., Psiroyiannis, A., Leotsinidis, M., Kyriazopoulou, V., Vassilakos, P., Zoumbos, N. (2005). Inappropriately low erythropoietin response for the degree of anemia in patients with noninsulin-dependent diabetes mellitus. Annals of Hematology, 85(2), 79-85. doi:10.1007/s00277-005-1102-9

Ulijaszek, S. J. (2003). Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation. WHO Technical Report Series 894. Pp. 252.

Viazzi, F., Leoncini, G., & Pontremoli, R. (2013). Antihypertensive Treatment and Renal Protection: The role of drugs inhibiting the renin-angiotensin-aldosterone system. High Blood Pressure & Cardiovascular Prevention, 20(4), 273-282. doi:10.1007/s40292-013-0027-y

Wish, J., Aronoff, G., Bacon, B., Brugnara, C., Eckardt, K. & Ganz, T., Wood, J. (2018). Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell? American Journal of Nephrology, 47(2), 72-83. doi:10.1159/000486968

World Health Organization (WHO) (2015). The global prevalence of anaemia in 2011. Geneva: World Health Organization. pag. 43.

World Health Organization (WHO). Obesity - Preventing and managing the global epidemic: Report of a WHO consultation. Geneva: World Health Organization, 2000, pag. 268.



How to Cite

SILVA, D. A. V. da; SILVA, L. C. de A. .; ANDRADE, Ícaro C. O. de; LIMA, A. S. de .; LIMA, J. P. da S.; OLIVEIRA, A. D. S. de . Factors associated with hemoglobin variation in women submitted to hemodialysis . Research, Society and Development, [S. l.], v. 10, n. 7, p. e13710716387, 2021. DOI: 10.33448/rsd-v10i7.16387. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/16387. Acesso em: 24 sep. 2023.



Health Sciences