Assessment of perioperative antibiotic prophylaxis for gynecological surgeries at an academic hospital in Brazil

Authors

DOI:

https://doi.org/10.33448/rsd-v10i8.17299

Keywords:

Antibiotic prophylaxis; Gynecologic surgical procedures; Practice patterns, physicians'.

Abstract

The aim of this study was to assess the adequacy of physicians' practice patterns regarding the use of perioperative antibiotic prophylaxis for gynecological surgeries in an academic hospital specialized in gynecology located at Rio de Janeiro city, Brazil. This is a retrospective study assessing all gynecological surgeries performed over one year. Appropriateness of antibiotic prophylaxis was determined according to criteria adapted from evidence-based guidelines. Clinical practice regarding the use of perioperative antibiotic prophylaxis was considered appropriate for 58.4% of 416 surgeries. The non-indicated use of antimicrobial prophylaxis was the main factor determining the low percentage of overall adequacy. Three variables were independently associated with inappropriate administration of perioperative antibiotics: patients age, breast surgeries and longer procedures. Antibiotic prophylaxis compliance to published recommendations is low. Women undergoing gynecological surgery are exposed to unnecessary risks associated to non-indicated use of antibiotic prophylaxis. Strategies aimed to improve compliance to evidence-based guidelines are necessary.

Author Biographies

Denise Ramos dos Santos, Federal University of Rio de Janeiro

Pharmacist at the Gynecology Institute of the Federal University of Rio de Janeiro, she is a specialist in Hospital Pharmacy from the Hospital Pharmacy Residency Program at the Fluminense Federal University and a Masters in Pharmaceutical Science and Technology from the Graduate Program in Pharmaceutical Science and Technology at FF/ UFRJ. It works in the areas of Pharmaceutical Assistance and Clinical Pharmacy.

Milene Rangel da Costa, Federal University of Rio de Janeiro

Associate Professor at the Faculty of Pharmacy of the Federal University of Rio de Janeiro, she has a Master's in Science in Biomedical Engineering from the Biomedical Engineering Program at COPPE/UFRJ and a Ph.D. in Biological Sciences/Biophysics from the Carlos Chagas Filho Biophysics Institute/UFRJ. He has a postdoctoral degree in Pharmacoeconomics at the Istituto di Ricerche Farmacologiche Mario Negri - Italy. He works in the areas of Health Technology Assessment, Health Economic Assessment and Applied Statistics.

 

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Published

13/07/2021

How to Cite

SANTOS, D. R. dos .; COSTA, M. R. da . Assessment of perioperative antibiotic prophylaxis for gynecological surgeries at an academic hospital in Brazil. Research, Society and Development, [S. l.], v. 10, n. 8, p. e30810817299, 2021. DOI: 10.33448/rsd-v10i8.17299. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/17299. Acesso em: 20 apr. 2024.

Issue

Vol. 10 No. 8

Section

Health Sciences

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Copyright (c) 2021 Denise Ramos dos Santos; Milene Rangel da Costa

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