Evaluation of pulp vitality using a pulse oximeter in patients undergoing radiotherapy for rhabdomyosarcoma or rhinopharynxcarcinoma

Authors

DOI:

https://doi.org/10.33448/rsd-v10i11.19342

Keywords:

Dental pulp; Oximetry; Radiotherapy; Rhabdomyosarcoma; Rinopharyngeal carcinoma.

Abstract

The oral cavity is highly susceptible to pathological changes due to the deleterious effects of radiation (RI) on tissues exposed during radiotherapy (RT). The aim of this study was to evaluate the feasibility of using pulse oximeter (PO) as a diagnostic instrument for assessing the pulp oxygenation level (%SpO2) of immature teeth previously exposure to IR. Pulp oxygenation saturation was evaluated in fifteen children or adolescent patients (Group RT) that received previous IR, 6.01 years ago (SD 4.08 years), and fifteen patients without a history of neoplasms or previous chemotherapy or radiotherapy (CO group). As result, the mean %SpO2 measured in Group RT and Group CO was 86.06% (SD 1.61%) and 91.11% (SD 0.87%), respectively. Conclusions: The use of the pulse oximeter adapted for dentistry for pulpal vitality evaluation in patients who received radiotherapy is feasible showing lower level of SpO2 than that of the control group (p<0.05).

References

Abd-Elmeguid, A., & Yu, D. C. (2009). Dental pulp neurophysiology: part 2. Current diagnostic tests to assess pulp vitality. Journal Canadian Dental Association, 75, 139-43.

Afanasyev, D. E., & Liubarets, S. F. Odontological effects of ionizing radiation (review). (2020). Problems of Radiation Medicine and Radiobiology, 25,18-55.

Caldeira, C. L., Barletta, F. B., Ilha, M. C., Abrão, C. V., & Gavini, G. (2016). Pulse oximetry: a useful test for evaluating pulp vitality in traumatized teeth. Dental Traumatology, 32, 385-9.

Anusha, B., Madhusudhana, K., Chinni, S. K., & Paramesh, Y. (2017). Assessment of Pulp Oxygen Saturation Levels by Pulse Oximetry for Pulpal Diseases –A Diagnostic Study. Journal of Clinical and Diagnostic Research, 11, 36-39.

Calil, E., Caldeira, C. L., Gavini, G., & Lemos, E. M. (2008). Determination of pulp vitality in vivo with pulse oximetry. International Endodontic Journal, 41, 741-6.

Cooper, J. S., Fu, K., Marks, J., & Silverman, S. (1995). Late effects of irradiation therapy in the head and neck region. International Journal of Radiation Oncology, Biology, Physics, 31, 1141-64.

Epstein, J. B., Thariat, J., Bensadoun, R. J., Barasch, A., Murphy, B. A., Kolnick, L., Popplewell, L., & Maghami, E. (2012). Oral complications of cancer and cancer therapy: from cancer treatment to survivorship. CA Cancer Journal for Clinicians, 62, 400-22.

Faria, K. M., Brandão, T. B., Ribeiro, A. C., Vasconcellos, A. F., de Carvalho, I. T., de Arruda, F. F., Castro Junior, G., Gross, V. C., Almeida, O. P., Lopes, M. A., & Santos-Silva, A. R. (2014). Micromorphology of the dental pulp is highly preserved in cancer patients who underwent head and neck radiotherapy. Journal of Endodontics, 40, 1553-9.

Garg, H., Grewal, M. S., Rawat, S., Suhag, A., Sood, P. B., Grewal, S., & Ahlawat, P. (2015). Dental Pulp Status of Posterior Teeth in Patients with Oral and Oropharyngeal Cancer Treated with Concurrent Chemoradiotherapy. Journal of Endodontics, 41, 1830-3.

Gheorghe, A. G., Mercuţ, V., Popescu, S. M., Mehedinţi, M. C., Ţuculina, M. J., Olimid, D., Lazǎr, A. D., Diaconu, O. A., & Moraru, A. I. (2019). Histological and immunohistochemical aspectsof the atrophic dental pulp modifications of abutment teeth. Romanian Journal of Morphology and Embryology, 60, 889-94.

Gopikrishna, V., Tinagupta, K., & Kandaswamy, D. (2007). Comparison of electrical, thermal, and pulse oximetry methods for assessing pulp vitality in recently traumatized teeth. Journal of Endodontics, 33, 531-5.

Grötz, K. A., Duschner, H., Kutzner, J., Thelen, M., & Wagner, W. (1998). Histotomography studies of direct radiogenic dental enamel changes. Mund Kiefer und Gesichtschirurgie, 2, 85-90.

Guggenheimer, J., Fischer, W. G., & Pechersky, J. L. (1975). Anticipation of dental anomalies induced by radiation therapy. Radiology, 117, 405-6.

Gupta, N., Grewal, M. S., Gairola, M., Grewal, S., & Ahlawat, P. (2018). Dental Pulp Status of Posterior Teeth in Patients with Oral and Oropharyngeal Cancer Treated with Radiotherapy: 1-year Follow-up. Journal of Endodontics, 44, 549-554.

Jafarzadeh, H., & Rosenberg, P. A. (2009). Pulse oximetry: review of a potential aid in endodontic diagnosis. Journal of Endodontics, 35, 329-33.

Kataoka S. H, Setzer F. C, Gondim-Junior E, Fregnani E. R, Moraes C. J, Pessoa O. F, Gavini G, & Caldeira C. L. (2016). Late Effects of Head and Neck Radiotherapy on Pulp Vitality Assessed by Pulse Oximetry. Journal of Endodontics, 42, 886-9

Kataoka S. H, Setzer F. C, Gondim-Junior E, Pessoa O. F, Gavini G, & Caldeira, C. L. (2011). Pulp vitality in patients with intraoral and oropharyngeal malignant tumors undergoing radiation therapy assessed by pulse oximetry. Journal of Endodontics, 37, 1197-200.

McMorrow, R. C., & Mythen M. G. (2006). Pulse oximetry. Current Opinion Critical Care,12, 269-71.

Miller, M. F., Luckenbach, J., & Chen, C. (1992). Clinical evaluation of a new saturation/hematocrit monitor. Journal of Extra-corporeal Technology, 24, 55-7.

Pigg, M, Nixdorf D. R, Nguye, R. H, & Law, A. S. (2016). Validity of Preoperative Clinical Findings to Identify Dental Pulp Status: A National Dental Practice-Based Research Network Study. Journal of Endodontics, 42, 935-42.

Pöder U, Ljungman G, & von Essen L. (2010). Parents' perceptions of their children's cancer-related symptoms during treatment: a prospective, longitudinal study. Journal of Pain and Symptom Management, 40, 661-70.

Pozzobon M. H, Vieira R S, Alves A. M. H, Reyes-Carmona J, Teixeira C. S, de Souza B D. M, & Felippe W. T. (2011). Assessment of pulp blood flow in primary and permanent teeth using pulse oximetry. Dental Traumatology, 27, 184-8.

Prasad S. P, Chinnaswamy G, Vora T, Prasad M, Bansal D, Kapoor G, Radhakrishnan V, Agarwala S, Laskar S, Arora B, Kaur T, Rath G. K, & Bakhshi S. (2017). Diagnosis and Management of Rhabdomyosarcoma in Children and Adolescents: ICMR Consensus Document. Indian Journal of Pediatrics, 84, 393–402.

Ribassin-Majed L, Marguet S, Lee A. W M, Ng W. T, Ma J, Chan A T C, Huang P Y, Zhu G, Chua D. T. T, Chen Y, Mai H. Q, Kwong D. L. W, Cheah S. L, Moon J, Tung Y, Chi K. H, Fountzilas G, Bourhis J, Pignon J. P, & Blanchard P. (2017). What Is the Best Treatment of Locally Advanced Nasopharyngeal Carcinoma? An Individual Patient Data Network Meta-Analysis. Journal of Clinical Oncology, 35, 498-505

Schnettler, J. M., & Wallace, J A. (1991). Pulse oximetry as a diagnostic tool of pulpal vitality. Journal of Endodontics, 17, 488-90.

Sennhenn-Kirchner S, Freund F, Grundmann S, Martin A, Borg-von Zepelin M, Christiansen H, Wolff H. A, & Jacobs H. G. (2009). Dental therapy before and after radiotherapy--an evaluation on patients with head and neck malignancies. Clinical Oral Investigations, 13,157-64.

Setzer, F. C, Kataoka, S. H, Natrielli, F, Gondim-Junior, E, & Caldeira, C. L. (2012). Clinical diagnosis of pulp inflammation based on pulp oxygenation rates measured by pulse oximetry. Journal of Endodontics, 38, 880-3.

Shahi, P, Sood, P B, Sharma, A, Madan, M, Shahi, N, & Gandhi, G. (2015). Comparative Study of Pulp Vitality in Primary and Young Permanent Molars in Human Children with Pulse Oximeter and Electric Pulp Tester. International Journal of Clinical Pediatric Dentistry, 8, 94–98.

Silva, A. R. S, Alves, F. A, Antunes, A, Goes M. F, & Lopes, M. A. (2009). Patterns os demineralization and dentin reactions in radiation-related caries. Caries Research, 43, 43-49.

Wexler, L H. (2016). Metastatic Rhabdomyosarcoma: Still Room for Improvement. Journal of Clinical Oncology, 34, 105-6.

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Published

24/08/2021

How to Cite

LOPES, R. P. .; AKISUE, E. .; NAKAMURA, V. C. .; CALDEIRA, C. L. .; LEMOS, Érico de M. .; CARRILLO, C. M. .; ROJZ, J. C. C. .; CARAN, E. M. M. Evaluation of pulp vitality using a pulse oximeter in patients undergoing radiotherapy for rhabdomyosarcoma or rhinopharynxcarcinoma. Research, Society and Development, [S. l.], v. 10, n. 11, p. e107101119342, 2021. DOI: 10.33448/rsd-v10i11.19342. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/19342. Acesso em: 19 apr. 2024.

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Section

Health Sciences