Prevalence of Staphylococcus aureus and MRSA among Medical students: a literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i11.19536

Keywords:

Staphylococcus aureus; Methicillin-resistant Staphylococcus aureus; MRSA; Medical Students; Clinical Stage; Nasal Carriage; Prevalence.

Abstract

Objective: The aim was to analyze the results of studies about the prevalence of Staphylococcus aureus and methicillin-resistant S. aureus among medical students. Methodology: A literature review was carried out from August to November 2020, being selected 19 articles from the Pubmed and “Biblioteca Virtual de Saúde” databases, using the descriptors “Methicillin-Resistant Staphylococcus aureus” and “Students, Medical”. Studies from the last 10 years that target medical students and samples collected by nasal swab were included. Results: Several studies have confirmed the hypothesis that, as students advanced in the academic years and, consequently, raised their exposure to hospital environments, colonization by methicillin-sensitive and resistant Staphylococcus aureus increased. However, some studies were divergent, not finding significant values ​​for this association. The prevalences found also varied according to the place and country surveyed. Conclusion: In general, the greater the exposure to hospital environments, the higher the rate of colonization of students by methicillin-resistant Staphylococcus aureus and Staphylococcus aureus.

References

Al-Tamimi, M., Himsawi, N., Abu-Raideh, J., Jazar, D. A., Al-Jawaldeh, H., Mahmoud, S. A. H., Hijjawi, N., & Hawamdeh, H. (2018). Nasal colonization by methicillin-sensitive and methicillin-resistant staphylococcus aureus among medical students. Journal of Infection in Developing Countries, 12(5), 326–335. https://doi.org/10.3855/jidc.9908

Alzoubi, H., Al Madadha, M., Al-Mnayyis, A., Azzam, M., Aldawoud, A., Hwaiti, D., Tarbiah, M., Abu Ajamieh, M., & Qatamin, M. (2020). Detection of Methicillin Susceptible and Resistant Staphylococcus aureus Nasal Carriage and Its Antibiotic Sensitivity among Basic and Clinical Years Medical Students. Healthcare, 8(2), 161. https://doi.org/10.3390/healthcare8020161

Ansari, S., Gautam, R., Shrestha, S., Ansari, S. R., Subedi, S. N., & Chhetri, M. R. (2016). Risk factors assessment for nasal colonization of Staphylococcus aureus and its methicillin resistant strains among pre-clinical medical students of Nepal. BMC Research Notes, 9(1), 1–8. https://doi.org/10.1186/s13104-016-2021-7

Budri, P. E., Shore, A. C., Coleman, D. C., Kinnevey, P. M., Humpreys, H., & Fitzgerald-Hughes, D. (2018). Observational cross-sectional study of nasal staphylococcal species of medical students of diverse geographical origin, prior to healthcare exposure: Prevalence of SCCmec, fusC, fusB and the arginine catabolite mobile element (ACME) in the absence of sele. BMJ Open, 8(4). https://doi.org/10.1136/bmjopen-2017-020391

Chamberlain, N. R., & Singh, V. K. (2011). Prevalence of methicillin resistant Staphylococcus aureus in nasal samples from preclinical second-year medical students. Missouri Medicine, 108(5), 373–376.

Chen, C. Y. C. S., Chen, C. Y. C. S., & Huang, Y. C. (2012). Nasal carriage rate and molecular epidemiology of methicillin-resistant Staphylococcus aureus among medical students at a Taiwanese university. International Journal of Infectious Diseases, 16(11), e799–e803. https://doi.org/10.1016/j.ijid.2012.07.004

Efa, F., Alemu, Y., Beyene, G., Gudina, E. K., & Kebede, W. (2019). Methicillin-resistant Staphylococcus aureus carriage among medical students of Jimma University, Southwest Ethiopia. Heliyon, 5(1), e01191. https://doi.org/10.1016/j.heliyon.2019.e01191

Evangelista, S. de S., & Oliveira, A. C. de. (2015). Staphylococcus aureus meticilino resistente adquirido na comunidade: um problema mundial. Revista Brasileira de Enfermagem, 68(1), 136–143. https://doi.org/10.1590/0034-7167.2015680119p

Geliebter, J., Reyes, N., Montes, O., Figueroa, S., Tiwari, R., Sollecito, C. C., Emmerich, R., Usyk, M., & Burk, R. D. (2020). Staphylococcus aureus nasal carriage and microbiome composition among medical students from Colombia: A cross-sectional study. F1000Research, 9(78), 1–16. https://doi.org/10.12688/f1000research.22035.2

Gualdoni, G. A., Lingscheid, T., Tobudic, S., & Burgmann, H. (2012). Low nasal carriage of drug-resistant bacteria among medical students in Vienna. GMS Krankenhaushygiene Interdisziplinär, 7(1), 1–4. https://doi.org/10.3205/dgkh000188

Ho, P. L., Lai, E. L., & Chow, K. H. (2015). Carriage of meticillin-susceptible and -resistant Staphylococcus aureus by medical students in Hong Kong. Journal of Hospital Infection, 91(2), 184–185. https://doi.org/10.1016/j.jhin.2015.06.012

Jayaweera, J. A. A. S., Pilapitiya, S., & Kumbukgolla, W. (2020). The relationship between the exposure to healthcare settings and colonization with methicillin-resistant Staphylococcus aureus among medical students. Germs, 10(1), 34–43. https://doi.org/10.18683/germs.2020.1217

López-Aguilera, S., Del Mar Goñi-Yeste, M., Barrado, L., González-Rodríguez-Salinas, C. M., Otero, J. R., & Chaves, F. (2013). Colonización nasal por Staphylococcus aureus en estudiantes de medicina: Importancia en la transmisión hospitalaria. Enfermedades Infecciosas y Microbiologia Clinica, 31(8), 500–505. https://doi.org/10.1016/j.eimc.2012.12.005

Ma, X. X., Sun, D. D., Wang, S., Wang, M. L., Li, M., Shang, H., Wang, E. H., & Luo, E. J. (2011). Nasal carriage of methicillin-resistant Staphylococcus aureus among preclinical medical students: Epidemiologic and molecular characteristics of methicillin-resistant S. aureus clones. Diagnostic Microbiology and Infectious Disease, 70(1), 22–30. https://doi.org/10.1016/j.diagmicrobio.2010.12.004

Okamo, B., Moremi, N., Seni, J., Mirambo, M. M., Kidenya, B. R., & Mshana, S. E. (2016). Prevalence and antimicrobial susceptibility profiles of Staphylococcus aureus nasal carriage among pre-clinical and clinical medical students in a Tanzanian University Microbiology. BMC Research Notes, 9(1), 1–6. https://doi.org/10.1186/s13104-016-1858-0

Orlin, I., Rokney, A., Onn, A., Glikman, D., & Peretz, A. (2017). Hospital clones of methicillin-resistant Staphylococcus aureus are carried by medical students even before healthcare exposure. Antimicrobial Resistance and Infection Control, 6(1), 1–10. https://doi.org/10.1186/s13756-017-0175-2

Rampal, S., Zainuddin, N. H., Elias, N. A., Jamaluddin, T. Z. M. T., Maniam, S., Teh, S. W., & Subbiah, S. K. (2020). Colonization of methicillin-resistant staphylococcus aureus (MRSA) among medical students in tertiary institution in Central Malaysia. Antibiotics, 9(7), 1–9. https://doi.org/10.3390/antibiotics9070382

Rodríguez-Avial, C., Álvarez-Novoa, A., Losa, A., & Picazo, J. J. (2013). Aumento significativo de la colonización por Staphylococcus aureus entre los estudiantes de medicina durante la realización de las prácticas en el hospital. Enfermedades Infecciosas y Microbiologia Clinica, 31(8), 516–519. https://doi.org/10.1016/j.eimc.2012.09.017

Santos, C. R. L. (2018). Vigilância epidemiológica de Staphylococcus aureus resistente a meticilina isolados de um hospital terciário público de Dourados/MS [Universidade Federal da Grande Dourados]. http://repositorio.ufgd.edu.br/jspui/handle/prefix/1072

Syafinaz, A. N., Nur Ain, N. Z. im, Nadzirah, S. N., Fatimah, J. S., Shahram, A., & Nasir, M. D. M. (2012). Staphylococcus aureus nasal carriers among medical students in A medical school. Medical Journal of Malaysia, 67(6), 636–638.

Szymanek-Majchrzak, K., Kosiński, J., Żak, K., Sułek, K., Młynarczyk, A., & Młynarczyk, G. (2019). Prevalence of methicillin resistant and mupirocin-resistant Staphylococcus aureus strains among medical students of Medical University in Warsaw. Przeglad Epidemiologiczny, 73(1), 39–48. https://doi.org/10.32394/pe.73.05

Treesirichod, A., Hantagool, S., & Prommalikit, O. (2013). Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study. Journal of Infection and Public Health, 6(3), 196–201. https://doi.org/10.1016/j.jiph.2012.12.004

Treesirichod, A., Hantagool, S., & Prommalikit, O. (2014). Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A follow-up study. Journal of Infection and Public Health, 7(3), 205–209. https://doi.org/10.1016/j.jiph.2013.12.003

Zakai, S. A. (2015). Prevalence of methicillin-resistant staphylococcus aureus nasal colonization among medical students in Jeddah, Saudi Arabia. Saudi Medical Journal, 36(7), 807–812. https://doi.org/10.15537/smj.2015.7.11609

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Published

03/09/2021

How to Cite

LEMOS, A. de S.; SOUZA, A. C. M. F. de .; KARAS, B.; CALIXTO, C. M.; MEIJERINK, C. I.; NASCIMENTO , F. C.; PINTO, G. P. C.; HESSMAN, J. H.; LONGO, L. B.; VELLOSA, J. C. R.; MONTES, E. G. Prevalence of Staphylococcus aureus and MRSA among Medical students: a literature review . Research, Society and Development, [S. l.], v. 10, n. 11, p. e347101119536, 2021. DOI: 10.33448/rsd-v10i11.19536. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/19536. Acesso em: 25 apr. 2024.

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Vol. 10 No. 11

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Review Article

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Copyright (c) 2021 Amanda de Souza Lemos; Ana Carolina Mello Fontoura de Souza; Bruna Karas; Camilla Mattia Calixto; Celine Iris Meijerink; Felipe Câncio Nascimento ; Gabriela Pires Corrêa Pinto; Julia Henneberg Hessman; Laura Bazzi Longo; José Carlos Rebuglio Vellosa; Elisangela Gueiber Montes

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