Sociodemographic and clinical profile of cancer patients in the context of the COVID-19 pandemic at a University Hospital in the Northeast: cross-sectional study

Authors

DOI:

https://doi.org/10.33448/rsd-v10i11.19611

Keywords:

COVID-19; Physiotherapy; Patient-generated health data; Oncology.

Abstract

The COVID-19 pandemic has overloaded public health services, making it a barrier to administering anti-cancer therapies. The restructuring of health services and the vulnerability of cancer patients contributed to the interruption of anticancer treatment. Thus, the objective was to describe the sociodemographic and clinical profile and main outcomes of adult and elderly cancer patients admitted to a university hospital (HU), undergoing physical therapy intervention, considering the previous and current period of the pandemic. Exploratory and retrospective study involving 71 cancer patients admitted to the HU in 2019 and 2020. Epidemiological data were collected through electronic medical records. Eligibility criteria were registration of the primary ICD related to cancer and age group (≥ 30 and ≥ 60 years). The statistical analysis considered the confounding variables: age, gender, place of residence, type of cancer, clinical outcome (discharge or death), physical therapy approaches (oxygen therapy, invasive and non-invasive mechanical ventilation) length of stay. The results demonstrate that gender was not a determining variable for hospitalization. Higher incidences of hospitalization were observed in the elderly, African descendants, patients with cancer of the colon/rectum and rectum, lung and, in equal percentage, cancers of the breast, stomach and oropharynx. Patients who required physical therapy and oxygen therapy follow-up evolved the outcome of death, regardless of the type of intervention (invasive or non-invasive mechanical ventilatory support). There was difference between the number of admissions and discharge and death outcomes in 2020 when compared to 2019.

References

Araujo, S. E. A., Leal, A., Centrone, A. F. Y., Teich, V. D., Malheiro, D. T., Cypriano, A. S., Cendoroglo, M., & Klajner, S. (2021). Impacto da COVID-19 sobre o atendimento de pacientes oncológicos: experiência de um centro oncológico localizado em um epicentro Latino-Americano da pandemia. Einstein (São Paulo), 19, eAO6282. https://doi.org/10.31744/einstein

Batista, T. S. C., Rebouças, D. A. de A., Almeida, L. A. da H., Santana, R. S., Fontes Junior, J., Santos, G. B., Silva, É. R., & Tofani, P. S. (2021). Telemonitoramento em usuários do SUS por estudantes de fisioterapia e fisioterapeutas durante a pandemia da COVID-19: relato de experiência / Telemonitoring in SUS users by physiotherapy students and physiotherapist during the COVID-19 pandemic: experienc. Brazilian Journal of Health Review, 4(3), 11071–11082. https://doi.org/10.34119/bjhrv4n3-114

Bergmann, A., Fabro, E. N., Silva, B. do A., Ribeiro, A. C. P., Lou, M., de Oliveira, J. F., Pedrosa, E., & Thuler, L. C. S. (2014). Sobrevida de mulheres com síndrome de compressão medular após metástase óssea secundária ao câncer de mama. Revista Neurociencias, 22(2), 195–200. https://doi.org/10.4181/RNC.2014.22.02.923.6p

Castro, A. A. M., Calil, S. R., Freitas, S. A., Oliveira, A. B., & Porto, E. F. (2013). Chest physiotherapy effectiveness to reduce hospitalization and mechanical ventilation length of stay, pulmonary infection rate and mortality in ICU patients. Respiratory Medicine, 107(1), 68–74. https://doi.org/10.1016/j.rmed.2012.09.016

Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., Xia, J., Yu, T., Zhang, X., & Zhang, L. (2020). Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet, 395(10223), 507–513. https://doi.org/10.1016/S0140-6736(20)30211-7

Dai, M., Liu, D., Liu, M., Zhou, F., Li, G., Chen, Z., Zhang, Z., You, H., Wu, M., Zheng, Q., Xiong, Y., Xiong, H., Wang, C., Chen, C., Xiong, F., Zhang, Y., Peng, Y., Ge, S., Zhen, B., … Cai, H. (2020). Patients with cancer appear more vulnerable to SARS-CoV-2: A multicenter study during the COVID-19 outbreak. Cancer Discovery, 10(6), 783. https://doi.org/10.1158/2159-8290.CD-20-0422

De França, E. T., Ferrari, F., Fernandes, P., Cavalcanti, R., Duarte, A., Martinez, B. P., Aquim, E. E., & Damasceno, M. C. P. (2012). Physical therapy in critically ill adult patients: Recommendations from the Brazilian Association of Intensive Care Medicine Department of Physical Therapy. Revista Brasileira de Terapia Intensiva, 24(1), 6–22. https://doi.org/10.1590/S0103-507X2012000100003

Dunford, A., Weinstock, D. M., Savova, V., Schumacher, S. E., Cleary, J. P., Yoda, A., Sullivan, T. J., Hess, J. M., Gimelbrant, A. A., Beroukhim, R., Lawrence, M. S., Getz, G., & Lane, A. A. (2017). Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias. Nature Genetics, 49(1), 10–16. https://doi.org/10.1038/ng.3726

Ellahham, S. H. (2019). Exercise Before, During, and After Cancer Therapy. American College of Cardiology, 1–12.

Emanuel, E. J., Persad, G., Upshur, R., Thome, B., Parker, M., Glickman, A., Zhang, C., Boyle, C., Smith, M., & Phillips, J. P. (2020). Fair Allocation of Scarce Medical Resources in the Time of Covid-19. New England Journal of Medicine, 382(21), 2049–2055. https://doi.org/10.1056/nejmsb2005114

Heath, E. I., Lynce, F., Xiu, J., Ellerbrock, A., Reddy, S. K., Obeid, E., Liu, S. V., Bollig-Fischer, A., Separovic, D., & Vanderwalde, A. (2018). Racial disparities in the molecular landscape of cancer. Anticancer Research, 38(4), 2235–2240. https://doi.org/10.21873/anticanres.12466

Instituto Nacional do Câncer José Alencar Gomes da Silva [INCA]. (2019). Estimativa 2020 - Incidência de Caâncer no Brasil.

Kuderer, N. M., Choueiri, T. K., Shah, D. P., Shyr, Y., Rubinstein, S. M., Rivera, D. R., Shete, S., Hsu, C. Y., Desai, A., de Lima Lopes, G., Grivas, P., Painter, C. A., Peters, S., Thompson, M. A., Bakouny, Z., Batist, G., Bekaii-Saab, T., Bilen, M. A., Bouganim, N., … West, J. (2020). Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. The Lancet, 395(10241), 1907–1918. https://doi.org/10.1016/S0140-6736(20)31187-9

Lee, L. Y. W., Cazier, J. B., Angelis, V., Arnold, R., Bisht, V., Campton, N. A., Chackathayil, J., Cheng, V. W. T., Curley, H. M., Fittall, M. W., Freeman-Mills, L., Gennatas, S., Goel, A., Hartley, S., Hughes, D. J., Kerr, D., Lee, A. J. X., Lee, R. J., McGrath, S. E., … Middleton, G. (2020). COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: A prospective cohort study. The Lancet, 395(10241), 1919–1926. https://doi.org/10.1016/S0140-6736(20)31173-9

Liang, W., Guan, W., Chen, R., Wang, W., Li, J., Xu, K., Li, C., Ai, Q., Lu, W., Liang, H., Li, S., & He, J. (2020). Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. The Lancet Oncology, 21(3), 335–337. https://doi.org/10.1016/S1470-2045(20)30096-6

MacDonald, P. L., & Gardner, R. C. (2000). Type I error rate comparisons of post hoc procedures for I × J chi-square tables. Educational and Psychological Measurement, 60(5), 735–754. https://doi.org/10.1177/00131640021970871

Marcucci, F. C. I. (2005). O papel da fisioterapia nos cuidados paliativos a pacientes com câncer. Revista Brasileira de Cancerologia, 51(1), 67–77.

Nascimento, C. C. do, Silva, P. H. dos S., Cirilo, S. S. V., & Silva, F. B. F. (2020). Desafios e Recomendações à Atenção Oncológica durante a Pandemia da Covid-19. Revista Brasileira de Cancerologia, 66(TemaAtual). https://doi.org/10.32635/2176-9745.rbc.2020v66ntemaatual.1241

NICE Guidelines. (2020). COVID-19 rapid guideline: delivery of systemic anticancer treatments [ng161]. National Institute for Health Care Excellence, April, 1–16. www.nice.org.uk/guidance/ng161

O’Driscoll, B. R., Howard, L. S., & Davison, A. G. (2008). BTS guideline for emergency oxygen use in adult patients. Thorax, 63(SUPPL. 6). https://doi.org/10.1136/thx.2008.102947

Paulista, J. S., Gonçalves Assunção, P., & Lopes Tavares de Lima, F. (2020). Acessibilidade da População Negra ao Cuidado Oncológico no Brasil: Revisão Integrativa. Revista Brasileira de Cancerologia, 65(4). https://doi.org/10.32635/2176-9745.rbc.2019v65n4.453

Pereira, A., Shitsuka, D., Parreira, F., & Shitsuka, R. (2018). Metodologia da pesquisa científica. In Metodologia da Pesquisa Científica. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1. Acesso em: 28 março 2020.

Pereira, É. R., Rodrigues, B. R. F., Gomes, E. S., Franco, F. S., Silveira, L. A. G., Cremonese, M., Pires, V. C. M. C., & Ferreira, W. S. (2021). Importância Da Fisioterapia Frente a Pandemia Provocada Pelo Novo Coronavírus / Importance of Physiotherapy in Front of the Pandemic Caused By New Coronavírus. Brazilian Journal of Development, 7(1), 9020–9030. https://doi.org/10.34117/bjdv7n1-612

Radbruch, L., Knaul, F. marie, Lima, L. de, Joncheere, C. de, & Bhadelia, A. (2020). Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-. The Lancet, January, 19–21.

Roberto, C., Carvalho, R. De, Junior, C. T., & Franca, S. A. (2007). III Consenso Brasileiro de Ventilação Mecância. Jornal Brasileiro de Pneumologia, 33(2), 54–70. papers2://publication/uuid/223B1428-5180-4A0E-BA25-E7D5CBCE28C5

Santos, H. L. P. C. dos, Maciel, F. B. M., & Oliveira, R. S. de. (2020). Internações Hospitalares por Neoplasias no Brasil, 2008-2018: Gastos e Tempo de Permanência. Revista Brasileira de Cancerologia, 66(3). https://doi.org/10.32635/2176-9745.rbc.2020v66n3.992

Santos, M., Corrêa, T. S., Faria, L. D. B., Siqueira, G. S. M. de, Reis, P. E. D. dos, & Pinheiro, R. N. (2019). Diretrizes Oncológicas 2. In Doctorpress.

Sarmento, G. J. (2015). O ABC da fisioterapia respiratória. In Editora Manole (Vol. 2).

Scala, R., & Pisani, L. (2018). Noninvasive ventilation in acute respiratory failure: Which recipe for success? European Respiratory Review, 27(149), 1–15. https://doi.org/10.1183/16000617.0029-2018

Silva, G. M., & Leão, L. T. D. S. (2012). O paradoxo da mistura Identidades , desigualdades e percepção de discriminação entre brasileiros pardos. Rbc, 27(80), 117–133.

Smith, Z. L., Eggener, S. E., & Murphy, A. B. (2017). African-American Prostate Cancer Disparities. Current Urology Reports, 18(10). https://doi.org/10.1007/s11934-017-0724-5

Spicer, J., Chamberlain, C., & Papa, S. (2020). Provision of cancer care during the COVID-19 pandemic. Nature Reviews Clinical Oncology, 17(6), 329–331. https://doi.org/10.1038/s41571-020-0370-6

The Lancet Oncology. (2020). COVID-19: global consequences for oncology. The Lancet Oncology, 21(4), 467. https://doi.org/10.1016/S1470-2045(20)30175-3

Thomas, P., Baldwin, C., Bissett, B., Boden, I., Gosselink, R., Granger, C. L., Hodgson, C., Jones, A. Y. M., Kho, M. E., Moses, R., Ntoumenopoulos, G., Parry, S. M., Patman, S., & van der Lee, L. (2020). Physiotherapy management for COVID-19 in the acute hospital setting: Recommendations to guide clinical practice. Pneumon, 33(1), 32–35. https://doi.org/10.1016/j.jphys.2020.03.011

Thuler, L. C. S., & Melo, A. C. de. (2020). SPacientes, S.-C.-. (2020). Sars-CoV-2 / Covid-19 em Pacientes com Câncer. 66(2), 19–20.ars-CoV-2 / Covid-19 em Pacientes com Câncer. 66(2), 19–20.

Tian, J., Yuan, X., Xiao, J., Zhong, Q., Yang, C., Liu, B., Cai, Y., Lu, Z., Wang, J., Wang, Y., Liu, S., Cheng, B., Wang, J., Zhang, M., Wang, L., Niu, S., Yao, Z., Deng, X., Zhou, F., … Wang, Z. (2020). Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study. The Lancet Oncology, 21(7), 893–903. https://doi.org/10.1016/S1470-2045(20)30309-0

Turaga, K. K., & Girotra, S. (2020). Are We Harming Cancer Patients by Delaying Their Cancer Surgery During the COVID-19 Pandemic? Annals of Surgery, Publish Ah. https://doi.org/10.1097/sla.0000000000003967

Wallace, C. L., Wladkowski, S. P., Gibson, A., & White, P. (2020). Grief During the COVID-19 Pandemic: Considerations for Palliative Care Providers. Journal of Pain and Symptom Management, 60(1), e70–e76. https://doi.org/10.1016/j.jpainsymman.2020.04.012

Wang, Y., Qiao, F., Zhou, F., & Yuan, Y. (2020). Surface distribution of severe acute respiratory syndrome coronavirus 2 in Leishenshan Hospital in China. Indoor and Built Environment, 26(7). https://doi.org/10.1177/1420326X20942938

Xavier, A. T. F., Ataíde, M. B. C., Pereira, F. G. F., & Nascimento, V. D. (2010). Análise de gênero para o adoecer de câncer. Revista Brasileira de Enfermagem, 63(6), 921–926. https://doi.org/10.1590/S0034-71672010000600008

Yang, K., Sheng, Y., Huang, C., Jin, Y., Xiong, N., Jiang, K., Lu, H., Liu, J., Yang, J., Dong, Y., Pan, D., Shu, C., Li, J., Wei, J., Huang, Y., Peng, L., Wu, M., Zhang, R., Wu, B., … Wu, G. (2020). Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study. The Lancet Oncology, 21(7), 904–913. https://doi.org/10.1016/S1470-2045(20)30310-7

Yedjou, C. G., Sims, J. N., Miele, L., Noubissi, F., Lowe, L., Fonseca, D. D., Alo, R. A., Payton, M., & Tchounwou, P. B. (2019). Health and Racial Disparity in Breast Cancer. Advances in Experimental Medicine and Biology, 1152, 31–49. https://doi.org/10.1007/978-3-030-20301-6_3

Published

30/08/2021

How to Cite

FONTES JÚNIOR, J. .; SILVA, Érika R. .; ALMEIDA, L. A. da H. .; SANTOS, C. N. dos; SOUZA, J. L. S. de .; BEZERRA, D. J. .; MATOS, C. J. O.; TOFANI, P. S. Sociodemographic and clinical profile of cancer patients in the context of the COVID-19 pandemic at a University Hospital in the Northeast: cross-sectional study. Research, Society and Development, [S. l.], v. 10, n. 11, p. e255101119611, 2021. DOI: 10.33448/rsd-v10i11.19611. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/19611. Acesso em: 25 apr. 2024.

Issue

Section

Health Sciences