Prevalence of the coinfection of the hepatitis B and Delta viruses among graduates at an university in Belém, Pará, Brazil

Authors

DOI:

https://doi.org/10.33448/rsd-v10i16.23855

Keywords:

Human Viral Hepatitis; Hepatitis B Virus; Hepatitis Delta Virus; HBsAg; HDVAg; Virology; Immunology.

Abstract

Introduction: The human Hepadnavirus are a kind of viruses responsible for the severe ailment of the liver, an essential organ for the perfect operation of the human body; this process happens as the viral hepatitis, which in Brazil,  still reaches na elevated number of individuals. Objective: This research intends to demonstrate the prevalence and epidemiologic characteristics of the Hepatitis B and Delta viruses in graduates at na University in Belém, Pará, Brazil. Materials and methods: This is a transversal study in which the academicians of the University Of Amazon, from the Alcindo Cacela campus whose attended the inclusion and exclusion criteria, willingly volunteered to participate in the research. The participants were applied a questionnaire to gather lifestyle information and immunochromatographic assay that, in the case of reactive result for hepatitis B, was to be followed by a blood sampling for posterior use in the ELISA assay in search of the HDVAg antigen. Results: 100 participants were included in this study, of which 44 (44%) of the participants were female, and 56 (56%) male. There was detected no cases of hepatitis Delta in the population involved. Conclusion: The prevalence of active (acute) cases of hepatitis B and/or Delta in the academic community is null, however, over 10% participants stated  to have already had contact with hepatitis.

References

Alves, B., Gonçalves, M. B., Fontoura, L. V. & Neves, G. D. (2017). Perfil Sexual de Estudantes Universitários. Revista Brasileira em Promoção da Saúde, 30 (4), 1-8.

Andrade, A. G., Duarte, P. C. A. V., Barroso, L. P., Nishimura, R., Alberghini, D. G. & Oliveira, L. G. (2012). Use of alcohol and other drugs among Brazilian college students: effects of gender and age. Revista Brasileira de Psiquiatria, 34 (3), 294-305.

Beudeker, B., Voermans, J., GeurtsvanKessel, C. H., de Knegt, R. J., Kuhlemann, T., Boonstra, A., & van der Eijk, A. A. (2021). Prevalence of hepatitis delta virus among chronic hepatitis B carriers in a large tertiary center in the Netherlands. Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology, 141, 104870. https://doi.org/10.1016/j.jcv.2021.104870

Castro, J., Almeida, C. & Rodrigues, V. (2019). Atitudes e comportamentos sexuais de risco em jovens universitários. Revista Motricidade, 15 (4), 41-45. https://doi.org/10.6063/motricidade.20138

Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis. (2021). Hepatite D. http://www.aids.gov.br/pt-br/publico-geral/hv/o-que-sao-hepatites/hepatite-d.

Duarte, G., Pezzuto, P., Barros, T. D., Junior, G. M. & Martínez-Espinosa, F. E. (2021). Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: hepatites virais. Epidemiologia e Serviços da Saúde, 30 (esp1), 1-8. https://doi.org/10.1590/S1679-4974202100016.esp1

Fonseca, J.C.F. (2002). Hepatite D. Revista da Sociedade Brasileira de Medicina Tropical, 35 (2), 181-190.

Hua, Z., Liu, R., Chen, Y., Liu, G., Li, C., Song, Y., Cao, Z., Li1, W., Li1, Lu, C. & Liu, W. (2021). Contamination of Aflatoxins Induces Severe Hepatotoxicity Through Multiple Mechanisms, Frontiers In Pharmacology, 11 (605823), 6-11. https://doi.org/10.3389/fphar.2020.605823

Huang, C. R., & Lo, S. J. (2014). Hepatitis D virus infection, replication and cross-talk with the hepatitis B virus. World journal of gastroenterology, 20 (40), 14589–14597. https://doi.org/10.3748/wjg.v20.i40.14589

Júnior, S. P. F., Rabelo, S. T. O., Lopes, E. M., Freitas, L. V., Pinheiro, a. K. B. & Ximenes, L. B. (2007). Perfil e práticas sexuais de universitários da área da saúde. Escola Anna Nery Revista de Enfermagem, 11 (1), 58-65.

Magnius, L., Taylor, J., Mason, W. S., Sureau, C., Dény, P. & Norder, H. (2018). ICTV Virus Taxonomy Profile: Deltavirus. Journal Of General Virology, 99, 1565-1566.

Ministério da Saúde, Secretaria de Vigilância em Saúde. (2019). Boletim Epidemiológico Especial. 19 (esp1), 35-67.

Ministério da Saúde, Secretaria de Vigilância em Saúde. (2020). Boletim Epidemiológico Especial. 20 (esp1), 39-67.

Ministério da Saúde, Secretaria de Vigilância em Saúde. (2021). Boletim Epidemiológico Especial. 21 (esp1), 35-67.

Oliveira, C. M. A., Nunes, M. R. T., Nunes, H. M. & Soares, M. C. P. (2012) Prevalência de marcadores sorológicos do vírus da hepatite B em profissionais de saúde de um laboratório de pesquisa na Amazônia oriental, Estado do Pará, Brasil, 2007 a 2009. Epidemiologia e Serviços de Saúde, 21 (4), 609-616.

Rizzetto, M. (2015). Hepatitis D Virus: Introduction and Epidemiology. Cold Spring Harbor Perspectives in Medicine, 5 (1), 1-8.

Stockdale, A. J., Kreuels, B., Henrion M. Y. R., De Martel, C., Hutin, Y. & Geretti, A. M. (2020). The global prevalence of Hepatitis D Virus infection: Systematic review and meta-analysis. Journal Of Hepatology, 73, 525-532. https://doi.org/10.1016/j.jhep.2020.04.008

Sung, H., Ferlay, J., Siegel, R.L., Laversanne, M., Soerjomataram, I., Jemal, A. & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 71, 209- 249. https://doi.org/10.3322/caac.21660

Urban, S., Neumann-Haefelin, C., & Lampertico, P. (2021). Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease. Gut, 70 (9), 1782–1794. https://doi.org/10.1136/gutjnl-2020-323888

World Health Organization. (2021). Hepatitis B. https://www.who.int/en/news-room/fact-sheets/detail/hepatitis-b.

Published

13/12/2021

How to Cite

CRISPIM, R. S. S. .; SANT’ANNA, C. de C. .; SANTOS, Érika C. P. T. .; PANTOJA, C. C. C. .; ALMEIDA, M. K. C. de . Prevalence of the coinfection of the hepatitis B and Delta viruses among graduates at an university in Belém, Pará, Brazil. Research, Society and Development, [S. l.], v. 10, n. 16, p. e352101623855, 2021. DOI: 10.33448/rsd-v10i16.23855. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/23855. Acesso em: 25 apr. 2024.

Issue

Section

Health Sciences