Advances and challenges in the diagnosis of paracoccidioidomycosis caused by the paracoccidioides species complex: integrative review
DOI:
https://doi.org/10.33448/rsd-v11i3.26152Keywords:
Paracoccidioidomycosis; Paracoccidioidomycosis diagnostic; Paracoccidioidomycosis analysis.Abstract
The following article show the classic diagnosis and some advances in paracoccidioidomycosis, an infectious disease with a spectrum of acute, subacute, or chronic evolution caused by the fungus Paracoccidioides spp. The disease is contracted through inhalation of an airborne fungal particles, having as main symptoms, cough, shortness of breath, weight loss and skin or mucous membrane lesions. Clinical symptoms make a correct diagnosis difficult, given the similarity with other diseases, such as tuberculosis and sarcoidosis, in addition to the fact that in some situations there may be an extended period between the individual's exposure to the fungus and the manifestation of symptoms. Taking this into account, the aim of this work is to evaluate and discuss diagnostic methods, as well as identify new advances made by molecular, serological, mycological, and histopathological methods for this mycosis. For this purpose, a reading of case studies, an experimental essay and a systematic review were carried out.
References
Abreu, M. A. M. M. D., Lastória, J. C., Mattos, A. L. D. A., & Alchorne, M. M. D. A. (2017). Paracoccidioidomycosis with sarcoid-like lesions: a diagnostic challenge. Revista da Sociedade Brasileira de Medicina Tropical, 50, 273-276. https://doi.org/10.1590/0037-8682-0246-2016
Bernardino, P. M., Azarias, A. C. F., dos Santos, F. G. J., Braga, A., & Junior, W. C. (2021). Paracoccidiomicose juvenil: um relato de caso. Revista Eletrônica Acervo Saúde, 13(2), e5953-e5953. https://doi.org/10.25248/reas.e5953.2021
Benard, G., Costa, A. N., Leopércio, A. P. S., Vicentini, A. P., Kono, A., & Shikanai-Yasuda, M. A. (2013). Chronic paracoccidioidomycosis of the intestine as single organ involvement points to an alternative pathogenesis of the mycosis. Mycopathologia, 176(5), 353-357. https://doi.org/10.1007/s11046-013-9699-z.
Brito, T. G. N. D., Taborda, M., Provenci, B., Costa, A. N., & Benard, G. (2021). A Case-Control Study of Paracoccidioidomycosis in Women: The Hormonal Protection Revisited. Journal of Fungi, 7(8), 655. https://doi.org/DOI: 10.3390/jof7080655
Brito, L. F. N. de et al., (2016). Influência do tratamento ortodôntico na reabsorção radicular: uma revisão sistemática. RFO UPF, v. 21, n. 2, p. 231-236.
Buccheri, R., dos Santos Morais, V., Kamikawa, C. M., Vidal, M. S. M., Naves, G., Del Negro, G. M. B., ... & Benard, G. (2018). Case Report: Misleading Serological Diagnosis of Paracoccidioidomycosis in a Young Patient with the Acute Form Disease: Paracoccidioides brasiliensis or Paracoccidioides lutzii?. The American journal of tropical medicine and hygiene, 98(4), 1082. https://doi.org/10.4269/ajtmh.17-0812
Canteros, C. E. (2018). Paracoccidioidomicosis: crónica de una enfermedad olvidada. Revista Medicina, 78(3).
Cocio, T. A., & Martinez, R. (2021). Serological diagnosis of paracoccidioidomycosis using a Paracoccidioides spp. comercial antigen and the counterimmunoelectrophoresis method. The Brazilian Journal of Infectious Diseases, 25(5), 101607. https://doi.org/10.1016/j.bjid.2021.101607
Costa, A. F. P., Dos Santos, V. M., Leite, M. R., & de Farias Filho, F. T. (2019). A Brazilian male with typical oral and pulmonary paracoccidioidomycosis. Medical journal of the Islamic Republic of Iran, 33, 145. https://doi.org/10.34171/mjiri.33.145
Cruz, E. R. D., Forno, A. D., Pacheco, S. A., Bigarella, L. G., Ballotin, V. R., Salgado, K., ... & Soldera, J. (2021). Intestinal Paracoccidioidomycosis: Case report and systematic review. Brazilian Journal of Infectious Diseases, 25. https://doi.org/10.1016/j.bjid.2021.101605
do Valle, A. C. F., de Macedo, P. M., Almeida-Paes, R., Romão, A. R., dos Santos Lazéra, M., & Wanke, B. (2017). Paracoccidioidomycosis after highway construction, Rio de Janeiro, Brazil. Emerging infectious diseases, 23(11), 1917. https://doi.org/10.3201/eid2311.170934
Hahn, R. C., Rodrigues, A. M., Della Terra, P. P., Nery, A. F., Hoffmann-Santos, H. D., Gois, H. M., ... & de Camargo, Z. P. (2019). Clinical and epidemiological features of paracoccidioidomycosis due to Paracoccidioides lutzii. PLoS neglected tropical diseases, 13(6), e0007437. https://doi.org/10.1371/journal.pntd.0007437
Higuita-Gutiérrez, L. F., Quintero-Quinchía, C., Madera-Miranda, I. C., & Cardona-Arias, J. A. (2019). Metanálisis de pruebas inmunológicas para el diagnóstico de la infección por Paracoccidioides, 1972-2017. Infectio, 23(2), 167-174. https://doi.org/10.22354/in.v23i2.774
Kamikawa, C. M., Mendes, R. P., & Vicentini, A. P. (2017). Standardization and validation of Dot-ELISA assay for Paracoccidioides brasiliensis antibody detection. Journal of Venomous Animals and Toxins including Tropical Diseases, 23. https://doi.org/10.1186/s40409-017-0101-3
Kayser, M., Rickerts, V., Drick, N., Gerkrath, J., Kreipe, H., Soudah, B., ... & Suhling, H. (2019). Chronic progressive pulmonary paracoccidioidomycosis in a female immigrant from Venezuela. Therapeutic advances in respiratory disease, 13, 1753466619894913. https://doi.org/10.1177/1753466619894913
Lomazi, E. A., de Negreiros, L. M. V., Magalhães, P. V. V. S., Togni, R. D. C. S., de Paiva, N. M., Ribeiro, A. F., & Leal, R. F. (2018). Intestinal paracoccidioidomycosis resembling Crohn’s disease in a teenager: a case report. Journal of medical case reports, 12(1), 1-4. https://doi.org/10.1186/s13256-018-1641-z
Martinez, R. (2017). New trends in paracoccidioidomycosis epidemiology. Journal of fungi, 3(1), 1. https://doi.org/10.3390/jof3010001
Mattos, K., Cocio, T. A., Chaves, E. G. A., Borges, C. L., Venturini, J., de Carvalho, L. R., ... & Weber, S. S. (2021). An update on the occurrence of Paracoccidioides species in the Midwest region, Brazil: Molecular epidemiology, clinical aspects and serological profile of patients from Mato Grosso do Sul State. PLoS neglected tropical diseases, 15(4), e0009317. https://doi.org/10.1371/journal.pntd.0009317
Merino-Alado, R., Pineda, J., Rasquin, J. H., Landaeta, M. E., & Mata-Essayag, S. (2020). Granulomatous mastitis due to coinfection with Histoplasma sp. and Paracoccidioides sp.: A case report. Medical mycology case reports, 27, 52-54. https://doi.org/10.1016/j.mmcr.2020.01.006
Moreira, A. L. E., Oliveira, M. A. P., Silva, L. O., Inácio, M. M., Bailão, A. M., Parente-Rocha, J. A., ... & Borges, C. L. (2020). Immunoproteomic approach of extracellular antigens from Paracoccidioides species reveals exclusive B-cell epitopes. Frontiers in microbiology, 10, 2968. https://doi.org/10.3389/fmicb.2019.02968
Nery, A. F., de Camargo, Z. P., Rodrigues, A. M., Portela, T. F., Hoffmann-Santos, H. D., Pinheiro, B. G., ... & Hahn, R. C. (2021). Puzzling paracoccidioidomycosis: Factors associated with the severity of Paracoccidioides lutzii infections. International Journal of Infectious Diseases, 107, 284-290. https://doi.org/10.1016/j.ijid.2021.05.002
Peçanha, P. M., Bahiense, I. C., Kruschewsky, W. L. L., Biasutti, C., Júnior, C. U. G. F., Pinheiro, B. G., ... & Gonçalves, S. S. (2021). Paracoccidioidomycosis due to Paracoccidioides brasiliensis S1 associated with acquired immunodeficiency syndrome: A case report. Revista Iberoamericana de Micología, 38(1), 5-8. https://doi.org/10.1016/j.riam.2020.09.003
Pereira, E. F., Gegembauer, G., Chang, M. R., Camargo, Z. P. D., Nunes, T. F., Ribeiro, S. M., ... & Paniago, A. M. (2020). Comparison of clinico-epidemiological and radiological features in paracoccidioidomycosis patients regarding serological classification using antigens from Paracoccidioides brasiliensis complex and Paracoccidioides lutzii. PLoS neglected tropical diseases, 14(8), e0008485. https://doi.org/10.1371/journal.pntd.0008485
Pinheiro, B. G., Pôssa, A. P., Della Terra, P. P., de Carvalho, J. A., Ricci, G., Nishikaku, A. S., ... & Rodrigues, A. M. (2021). A New Duplex PCR-Assay for the Detection and Identification of Paracoccidioides Species. Journal of Fungi, 7(3), 169. https://doi.org/10.3390/jof7030169
Pinheiro, B. G., Hahn, R. C., Camargo, Z. P. D., & Rodrigues, A. M. (2020). Molecular tools for detection and identification of Paracoccidioides species: Current status and future perspectives. Journal of Fungi, 6(4), 293. https://doi.org/10.3390/jof6040293
Roberto, T. N., Rodrigues, A. M., Hahn, R. C., & de Camargo, Z. P. (2015). Identifying Paracoccidioides phylogenetic species by PCR-RFLP of the alpha-tubulin gene. Sabouraudia, 54(3), 240-247. https://doi.org/10.1093/mmy/myv083
Rodrigues, A. M., Kubitschek-Barreira, P. H., Pinheiro, B. G., Teixeira-Ferreira, A., Hahn, R. C., & de Camargo, Z. P. (2020). Immunoproteomic analysis reveals novel candidate antigens for the diagnosis of paracoccidioidomycosis due to Paracoccidioides lutzii. Journal of Fungi, 6(4), 357. https://doi.org/10.3390/jof6040357
Santos, A. R. D., Dionizio, A., Fernandes, M. D. S., Buzalaf, M. A. R., Pereira, B., Donanzam, D. D. F. A., ... & Venturini, J. (2021). Proteomic analysis of serum samples of paracoccidioidomycosis patients with severe pulmonary sequel. PLoS neglected tropical diseases, 15(8), e0009714. https://doi.org/10.1371/journal.pntd.0009714
Silva, M. J. A., da Cruz, E. C., Gama, G. C. B., & Siqueira, A. S. (2021). Ecoepidemiologia da paracoccidioidomicose: Uma revisão narrativa da literatura. Research, Society and Development, 10(9), e31810918182-e31810918182. https://doi.org/10.33448/rsd-v10i9.18182
Sousa, J. A., Sá, R. S., & Pereira, E. M. (2021). Consequências do diagnóstico tardio de paracoccidioidomicose: relato de caso. Jornal Brasileiro de Patologia e Medicina Laboratorial, 57. https://doi.org/10.5935/1676-2444.20210003
Shikanai-Yasuda, M. A., Mendes, R. P., Colombo, A. L., Queiroz-Telles, F. D., Kono, A. S. G., Paniago, A. M., ... & Martinez, R. (2017). Brazilian guidelines for the clinical management of paracoccidioidomycosis. Revista da Sociedade Brasileira de Medicina Tropical, 50, 715-740. https://doi.org/10.5123/S1679-49742018000500001
Queiroz-Telles, F. V., Peçanha Pietrobom, P. M., Rosa Júnior, M., Baptista, R. M., & Peçanha, P. M. (2020). New Insights on Pulmonary Paracoccidioidomycosis. Seminars in respiratory and critical care medicine, 41(1), 53–68. https://doi.org/10.1055/s-0039-3400544
Wagner, G., Moertl, D., Glechner, A., Mayr, V., Klerings, I., Zachariah, C., ... & Willinger, B. (2021). Paracoccidioidomycosis Diagnosed in Europe—A Systematic Literature Review. Journal of Fungi, 7(2), 157. https://doi.org/10.3390/jof7020157
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Copyright (c) 2022 Jéssica Brenda de Sousa Trindade; Aléxia Vasconcelos Diniz; Even Herlany Pereira Alves; Sâmylla Moita Lopes; Clara Bittencourt Lima; Jacks Renan Neves Fernandes; Thayaná Ribeiro Silva Fernandes; Valéria de Fátima Veras de Castro; Daniel Fernando Pereira Vasconcelos; Lenilson do Nascimento Melo Junior
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