Clinical evaluation of the presence of hyposalivation in chronic renal patients on hemodialysis

Authors

DOI:

https://doi.org/10.33448/rsd-v11i4.27042

Keywords:

Chronic Renal Insufficiency; Renal Dialysis; Saliva.

Abstract

The objective of this study was to determine the clinical and oral health conditions of chronic renal patients submitted to hemodialysis in the municipality of Patos-PB, Brazil. For data collection, a detailed anamnesis was performed, with extra and intraoral physical examination, arterial pressure gauging, oximetry with digital oximeter, sialometry with a millimeter test tube, and data collection in medical records. Thirty-five patients with a diagnosis of chronic renal failure participated in the study. According to the data, the majority was male (n = 23; 51.1%), with a mean age of 51.02, ranging from 22 to 80 years. The mean duration of nephropathy was 6.54 years, ranging from 0.08 to 59 years, and the two main causes were hypertension (n = 19, 42.2%) and diabetes (n = 6, 13.3%). The mean values of systolic and diastolic arterial pressures were indicative of arterial hypertension. The prevalence of xerostomia and hyposalivation were, respectively, 60.0% (n = 27) and 24.4% (n = 11). In addition, more than half of the patients had gingivitis (n = 27, 60.0%) and periodontitis (n = 23, 51.1%). The results of the laboratory tests showed that the mean values of urea (M = 115.96), calcium (M = 10.36) and phosphorus (M = 4.84) and glycemia (M = 158.05) were elevated. Regarding the hemoglobin and hematocrit values, the mean values were below the reference limits. The most prevalent comorbidities and risk factors were: hypertension (n = 31, 68.9%), stress (n = 25, 55.6%), smoking (n = 18, 40.0% 14, 31.1%) and cardiopathies (n = 14, 31.1%). There was a statistically significant association between hyposalivation and diabetes (p = 0.02). The proportion of hyposalivation was significantly higher among patients with diabetes (n = 7; 50.0%) compared to those without diabetes (n = 4; 12.9%). The patient with Chronic Kidney Disease needs special attention in the dental care because many oral complications can arise by the action of the Chronic Kidney Disease itself or by the action of comorbidities such as hyposalivation.

References

Alves, M. A. R. & Gordan, P. A. (2014). Diagnóstico de anemia em pacientes portadores de doença renal crônica. Jornal Brasileiro de Nefrologia, 36 (1), 9-12.

Baeder, F. M. (2021). Guia odontológico prático para atendimento do paciente de alta complexidade. Napoleão editora.

Bruzda-Zwiech, A., Szczepan´ska, J., Zwiech, R. (2014). Sodium gradient, xerostomia, thirst and inter-dialytic excessive weight gain: a possible relationship with hyposalivation in patients on maintenance hemodialysis. International Urology and Nephrology, 46, 1411–1417.

Capitanio, B. L. et al. (2016). Prevalência de doença periodontal em pacientes com insuficiência renal crônica em hemodiálise. Brazilian Journal of Periodontology, 26 (2), 14-22.

Diretrizes Brasileiras de Hipertensão. (2010). Revista brasileira de Hipertensão, 17 (1)

Gautam, N. (2014). Effect of end-stage renal disease on oral health in patients undergoing renal dialysis: A cross-sectional study. Journal of International Society of Preventive and Community Dentistry, 4 (3), 164-169.

Gesualdo, G. D. et al. (2016). Fatores associados à fragilidade de idosos com doença renal crônica em hemodiálise. Ciência & Saúde Coletiva, 21 (11), 3493-3498.

Gonçalves, E. M. et al. (2007). Prevalência de Periodontite em Pacientes submetidos à Hemodiálise. Jornal Brasileiro de Nefrologia, 29 (3), 115-119.

Junior, H. R. O., Formiga, F. F. C., Alexandre, C. S. (2014). Perfil clínico-epidemiológico dos pacientes em programa crônico de hemodiálise em João Pessoa – PB. Jornal Brasileiro de Nefrologia, 36 (3), 367-374.

Larson, R., Farber, B. (2016). Estatística Aplicada. Pearson Prentice Hall.

Little, J. M. et al.(2008). Manejo Odontológico do Paciente clinicamente comprometido. Elsevier.

Martins, C., Siqueira, W. L., Primo, L. S. S. G. (2008). Oral and salivary flow characteristics of a group of Brazilian children and adolescents with chronic renal failure. Pediatric Nephrology, 23 (4), 619-624.

Miguel, L. C. M., Locks, A., Neumann, V. (2006). Redução do fluxo salivar em hemodialisados. Jornal Brasileiro de Nefrologia, 28 (1), 20-24.

Moreira, A. R. et al. (2007). Hipossalivação e aumento da glicose salivar em diabéticos. Revista Odonto, 15 (30),78-82.

Newman, M.G. et al. (2007). Periodontia Clínica.. Elsevier.

Oliveira, C. S. et al. (2015). Perfil dos pacientes renais crônicos em tratamento hemodialítico. Revista Baiana de Enfermagem, 29 (1), 42-49.

Pereira A. S. et al. (2018). Metodologia da pesquisa científica.

Proctor, R. et al. (2005). Oral and Dental Aspects of Chronic Renal Failure. Journal of Dental Research, 84 (3), 199-208.

Ramos, F. R. B. A. A. (2017). Xerostomia e hipossalivação: Avaliação em pacientes diabéticos tipo 2 no município de Patos-PB. Trabalho de Conclusão de Curso.

Silva,J.L.,Barbosa,P.S.S.,Sousa,H.W.O. (2008). Avaliação da dosagem de ureia pré e pós hemodiálise em pacientes em terapia renal substitutiva. Revista eletrônica de farmácia, 5 (2), 43-47.

Silva, S. B. e, Silva , I. A. P. S. ., Santos , G. A., Marangon junior, H. ., Almeida, A. L. P. de ., Andrade, R. S. de. ( 2021). Doença renal crônica: influencia sistêmica na odontologia e manifestações bucais. Research, Society and Development, 10 (14), e382101422055.

Souza, A. B. et al. (2010). Caracterização de pacientes com IRC em tratamento hemodialítico em uma clínica privada em Natal – RN. Fiep bulletin, 80 (2), 1-6.

Sociedade brasileira de anestesiologia. (2013). Tutorial de Anestesia da Semana Oximetria de Pulso Parte I.

Published

10/03/2022

How to Cite

MEDEIROS, S. A. .; OLIVEIRA, I. C. R. .; SILVA, D. F. .; BAEDER, F. M. .; CORAZZA, P. F. L. .; SOARES, M. S. M. .; COSTA, L. J. da .; ALBUQUERQUE, A. C. L. de . Clinical evaluation of the presence of hyposalivation in chronic renal patients on hemodialysis. Research, Society and Development, [S. l.], v. 11, n. 4, p. e3711427042, 2022. DOI: 10.33448/rsd-v11i4.27042. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/27042. Acesso em: 26 apr. 2024.

Issue

Section

Health Sciences