Local anesthetics in Dentistry: a literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i4.27287

Keywords:

Vasoconstrictors; Local Anesthetics; Systemic complications.

Abstract

Local anesthesia is essential for performing the vast majority of dental procedures. Mortality cases due to local anesthesia are rare. However, cases of morbidity are more common but not always reported. Given the above, this study aimed to review the literature on local anesthetics used in dentistry, highlighting necessary information regarding the choice and amount of anesthetic, preventing the occurrence of complications. For the construction of this work, a bibliographic survey was carried out in the SciVerse Scopus, Scientific Electronic Library Online (Scielo), U.S. National Library of Medicine (PUBMED) and ScienceDirect databases, using the Mendeley reference manager. Scientific studies available in the literature report. Standardizing a solution for general use does not always satisfy the clinical needs and well-being of patients, and can even cause serious problems for them. Although all local anesthetics currently used have similar mechanisms of action, they may differ in terms of duration of action, pharmacological effects, metabolism, associated vasoconstrictor, adverse reactions and, therefore, indications. Thus, the professional must choose the anesthetic solution according to the patient and the procedure to be performed. The best treatment for systemic complications arising from local anesthesia is undoubtedly prevention, through a good anamnesis and physical examination, choosing the safest anesthetic salt for each specific case.

References

Alsukhni, R. A., Ghoubari, M. S., Farfouti, M. T., & Aboras, Y. A. (2016). Status epilepticus following local anesthesia in a previously healthy adult. BMC Research Notes, 9(1), 300. https://doi.org/10.1186/s13104-016-2100-9

Altan, A. (2020). Accidental injection of ethylenediaminetetraacetic acid (EDTA) instead of an anaesthetic solution: a case report. Journal of Stomatology, Oral and Maxillofacial Surgery, 121(1), 77–79. https://doi.org/https://doi.org/10.1016/j.jormas.2019.03.014

Asan, C. Y., Ağyüz, G., Canpolat, D. G., Demirbas, A. E., Asan, M., Yay, A., Ülger, M., & Karakükcü, Ç. (2022). Chondrotoxic effects of intra-articular injection of local anaesthetics in the rabbit temporomandibular joint. International Journal of Oral and Maxillofacial Surgery. https://doi.org/https://doi.org/10.1016/j.ijom.2022.01.011

Bernstein, W. K., Wyrobek, J., Vidovich, C., Tang, J., Lindenmuth, D., & Gosev, I. (2021). Anesthetic Considerations for Minimally Invasive, Off-Pump, HeartMate III Implantation. Journal of Cardiothoracic and Vascular Anesthesia. https://doi.org/https://doi.org/10.1053/j.jvca.2021.12.028

Brandt, R. G., Anderson, P. F., McDonald, N. J., Sohn, W., & Peters, M. C. (2011). The pulpal anesthetic efficacy of articaine versus lidocaine in dentistry: A meta-analysis. The Journal of the American Dental Association, 142(5), 493–504. https://doi.org/https://doi.org/10.14219/jada.archive.2011.0219

Daly, S., Claydon, N. C. A., Newcombe, R. G., Seong, J., Addy, M., & West, N. X. (2021). Randomised controlled trial of a microneedle patch with a topical anaesthetic for relieving the pain of dental injections. Journal of Dentistry, 107, 103617. https://doi.org/https://doi.org/10.1016/j.jdent.2021.103617

Decloux, D., & Ouanounou, A. (2021). Local Anaesthesia in Dentistry: A Review. International Dental Journal, 71(2), 87–95. https://doi.org/https://doi.org/10.1111/idj.12615

Ege, B., Ege, M., Koparal, M., & Alan, H. (2020). Comparison of the Anesthetic Efficiency of Lidocaine and Tramadol Hydrochloride in Orthodontic Extractions: A Split-Mouth, Prospective, Randomized, Double-Blind Study. Journal of Oral and Maxillofacial Surgery, 78(1), 52–62. https://doi.org/https://doi.org/10.1016/j.joms.2019.07.010

El-Boghdadly, K., Pawa, A., & Chin, K. J. (2018). Local anesthetic systemic toxicity: current perspectives. Local and Regional Anesthesia, 11, 35–44. https://doi.org/10.2147/LRA.S154512

Kauferstein, S., Kiehne, N., Peigneur, S., Tytgat, J., & Bratzke, H. (2013). Cardiac channelopathy causing sudden death as revealed by molecular autopsy. International Journal of Legal Medicine, 127(1), 145–151. https://doi.org/10.1007/s00414-012-0679-5

L. C. A., PAIVA, & A. L., C. (2005). Anestésicos Locais Em Odontologia: Uma Revisão De Literatura. Publicatio UEPG: Ciencias Biologicas e Da Saude, 11(2), 35–42. https://doi.org/10.5212/publ.biologicas.v.11i2.0005

Mane, R. J., Choi, J. J. E., & Sharpe-Davidson, W. F. (2021). Tramadol as a local anaesthetic agent in dentistry: A systematic review of local and systemic adverse effects. The Saudi Dental Journal, 33(8), 842–852. https://doi.org/https://doi.org/10.1016/j.sdentj.2021.09.015

Sekimoto, K., Tobe, M., & Saito, S. (2017). Local anesthetic toxicity: acute and chronic management. Acute Medicine & Surgery, 4(2), 152–160. https://doi.org/10.1002/ams2.265

Seminario-Amez, M., González-Navarro, B., Ayuso-Montero, R., Jané-Salas, E., & López-López, J. (2021). USE OF LOCAL ANESTHETICS WITH A VASOCONSTRICTOR AGENT DURING DENTAL TREATMENT IN HYPERTENSIVE AND CORONARY DISEASE PATIENTS. A SYSTEMATIC REVIEW. Journal of Evidence Based Dental Practice, 21(2), 101569. https://doi.org/https://doi.org/10.1016/j.jebdp.2021.101569

Vishal, G., Dandriyal, R., Indra B., N., Singh, H. P., & Chaurasia, A. (2021). Comparative study of the anaesthetic efficacy of 4% articaine versus 2% lidocaine with adrenaline during extraction of mandibular molars using an inferior alveolar nerve blocking technique. British Journal of Oral and Maxillofacial Surgery, 59(7), 783–787. https://doi.org/https://doi.org/10.1016/j.bjoms.2020.09.017

Published

15/03/2022

How to Cite

SÁ, A. C. S. F. de .; SOUZA, T. P. P. de .; BORBA, T. O. da S.; REIS, J. L. .; CASTRO , J. de S. .; SOARES, M. C. A. .; ARAÚJO, E. L. da S. F. de .; SILVA, L. F. da; CAPELARIO, E. de F. S. .; BUZINARO, G. S. .; FREITAS, D. da P. .; FRANCO, A. G. .; PEREIRA, L. D. .; SOUSA, M. F. de O. .; GOMES, L. A. B.; SOUZA, M. F. A. de .; LOPES, G. M. . Local anesthetics in Dentistry: a literature review. Research, Society and Development, [S. l.], v. 11, n. 4, p. e18011427287, 2022. DOI: 10.33448/rsd-v11i4.27287. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/27287. Acesso em: 27 apr. 2024.

Issue

Section

Health Sciences