Toxoplasmosis in dogs and cats in the backland’s mesoregion, northeastern Brazil

Authors

DOI:

https://doi.org/10.33448/rsd-v11i4.27463

Keywords:

Pet disease; Immunosuppression; Toxoplasma gondii.

Abstract

The clinical and anatomopathological aspects of toxoplasmosis in dogs and cats in the backland’s mesoregion, northeastern Brazil, are described. From 2003 to 2019, the Animal Pathology Laboratory of the Federal University of Campina Grande performed 2,521 necropsies on dogs and 1,332 on cats, of which 17 cases of toxoplasmosis were diagnosed. Dogs of both sexes with ages ranging from 5 months to 9 years were affected. Most of the animals were of mixed breed and semi-domiciled, with concomitant infection by the Canine Distemper Virus. Cats of both sexes ranging in age from 3 months to 3.5 years, mixed breed and semi-domiciled were affected. Most dogs showed neurological signs, while cats’ nonspecific symptoms. Necropsy revealed whitish multifocal areas on the lungs and liver. Histopathology revealed multifocal areas of necrosis associated with tachyzoites of Toxoplasma gondii. In dogs, pathological findings consistent with distemper were identified. The diagnosis of toxoplasmosis was established based on the pathological findings and histomorphological characteristics of the agent, which was confirmed by immunohistochemistry. It is concluded that toxoplasmosis is a systemic disease in dogs and cats, and which in dogs is usually associated with immunosuppression caused by distemper. Immunohistochemistry is recommended to confirm the post-mortem diagnosis.

References

Aguiar, D. M., Amude, A. M., Santos, L. G. F., Ribeiro, M. G., Ueno, T. E. H., Megid, J., Paes, A. C., Alfieri, A. F., & Gennari, S. M. (2012). Canine distemper virus and Toxoplasma gondii co-infection in dogs with neurological signs. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 64(1), 221-224.

Akhtardanesh, B., Ziaali, N., Sharifi, H., & Rezaei, S. (2010). Feline immunodeficiency virus, feline leukemia virus and Toxoplasma gondii in stray and household cats in Kerman–Iran: Seroprevalence and correlation with clinical and laboratory findings. Research in veterinary science, 89(2), 306-310.

Appel, M. J., & Summers, B. A. (1995). Pathogenicity of morbilliviruses for terrestrial carnivores. Veterinary microbiology, 44(2-4), 187-191.

Atmaca, H. T., Dincel, G. C., Macun, H. C., Terzi, O. S., Uzunalioglu, T., Kalender, H., & Kul, O. (2013). A rare case of feline congenital Toxoplasma gondii infection: fatal outcome of systemic toxoplasmosis for the mother and its kitten. Berliner und Munchener tierarztliche Wochenschrift, 126(5-6), 216-219.

Azevedo, S. S., Batista, C. S. A., Vasconcellos, S. A., Aguiar, D. M., Ragozo, A. M. A., Rodrigues, A. A. R., Alves, C. J., & Gennari, S. M. (2005). Seroepidemiology of Toxoplasma gondii and Neospora caninum in dogs from the state of Paraíba, Northeast region of Brazil. Research in Veterinary Science, 79(1), 51-56.

Bresciani, K. D. S., Gennari, S. M., Serrano, A. C. M., Rodrigues, A. A. R., Ueno, T., Franco, L. G., Perri, S. H. V., & Amarante, A. F. T. (2007). Antibodies to Neospora caninum and Toxoplasma gondii in domestic cats from Brazil. Parasitology Research, 100(2), 281-285.

Calero-Bernal, R., & Gennari, S. M. (2019). Clinical toxoplasmosis in dogs and cats: an update. Frontiers in veterinary science, 6, 54.

Dubey, J.P. (2010) Toxoplasmosis of Animals and Humans. 2nd edition. Boca Raton, Florida: CRC Press. p.313.

Dubey, J. P. (2004). Toxoplasmosis–a waterborne zoonosis. Veterinary parasitology, 126(1-2), 57-72.

Dubey, J. P. (1995). Duration of immunity to shedding of Toxoplasma gondii oocysts by cats. The Journal of parasitology, 81(3), 410-415.

Elmore, S. A., Jones, J. L., Conrad, P. A., Patton, S., Lindsay, D. S., & Dubey, J. P. (2010). Toxoplasma gondii: epidemiology, feline clinical aspects, and prevention. Trends in parasitology, 26(4), 190-196.

Fernandes, A. R. F., Costa, D. F., Andrade, M. R., Bezerra, C. S., Mota, R. A., Alves, C. J., Langoni, H., & Azevedo, S. S. (2018). Soropositividade e fatores de risco para leptospirose, toxoplasmose e neosporose na população canina do Estado da Paraíba. Pesquisa Veterinária Brasileira, 38(5), 957-966.

Fialho, C. G., Teixeira, M. C., & Araújo, F. A. P. (2009). Toxoplasmose animal no Brasil. Acta Scientiae Veterinariae, 37(1), 1-23.

Frade, M. T. S., Maia, L. Â., Andrade, R. L. F. S., Alves, R. C., Yamasaki, E. M., Mota, R. A., & Dantas, A. F. M. (2015). Caracterização clínica, patológica e imuno-histoquímica da toxoplasmose em cães com cinomose no semiárido da Paraíba, Brasil. Semina: Ciências Agrárias, 36(2), 4251-4256.

Frenkel, J. K., & Bermudez, J. E. V. (2006). Toxoplasmose. In: Veronesi, R., & Focaccia, R. (Orgs). Tratado de infectologia pp. 1634-1649. São Paulo: Atheneu.

Galvão, A. L. B., Vaconcellos, A. L., Navarro, I. T., & Bresciani, K. D. S. (2014). Aspectos da toxoplasmose na clínica de pequenos animais. Semina: Ciências Agrárias, 35(1), 393-409.

Giraldi, J. H., Bracarense, A. P. F. R. L., Vidotto, O., Tudury, E. A., Navarro, I. T., & Batista, T. N. (2002). Sorologia e histopatologia de Toxoplasma gondii e Neospora caninum em cães portadores de distúrbios neurológicos. Semina: Ciências Agrárias, Londrina, 23(1), 9-14.

Lima, T. S., Souto, E. P. F., Alves, R. C., Bezerra, L. S., Ribeiro, R. C. S., Galiza, G. J. N., Sousa, A. P., & Dantas, A. F. M. (2019). Toxoplasmose sistêmica em filhotes de gatos. Acta Scientiae Veterinariae, 47(1), 378.

Lucas, S. R. R., Hagiwara, M. K., Reche Jr, A., & Germano, P. M. L. (1998). Ocurrence of antibodies to Toxoplasma in cats naturally infected with feline immunodeficiency virus. Brazilian Journal of Veterinary Research and Animal Science, 35(1), 41-45.

Moretti, L. A., Ueno, T. E., Ribeiro, M. G., Aguiar, D. M., Paes, A. C., Pezerico, S. B., & da Silva, A. V. (2002). Toxoplasmose em cães co-infectados com o vírus da cinomose. Semina: Ciências Agrárias, Londrina, 23(1), 85-91.

Pena, H. F. D. J., Evangelista, C. M., Casagrande, R. A., Biezus, G., Wisser, C. S., Ferian, P. E., ... & Traverso, S. D. (2017). Fatal toxoplasmosis in an immunosuppressed domestic cat from Brazil caused by Toxoplasma gondii clonal type I. Revista Brasileira de Parasitologia Veterinária, 26, 177-184.

Uzal FA, Plattner BL, Hostetter JM. Alimentary system. In: Maxie MG. (Ed). Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals. 6th edn. St. Louis: Elsevier; 2016. p.139-140.

Published

23/03/2022

How to Cite

PEREIRA, J. K. D. M.; SOUTO, E. P. F. de; OLIVEIRA, A. M. de .; LIMA, A. L. de; SOUZA, A. P. de; GALIZA, G. J. N. de; FRADE, M. T. S.; DANTAS, A. F. M. . Toxoplasmosis in dogs and cats in the backland’s mesoregion, northeastern Brazil. Research, Society and Development, [S. l.], v. 11, n. 4, p. e44711427463, 2022. DOI: 10.33448/rsd-v11i4.27463. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/27463. Acesso em: 18 apr. 2024.

Issue

Section

Agrarian and Biological Sciences