Osteomyelitis by Sporothrix spp. in a dog
DOI:
https://doi.org/10.33448/rsd-v11i4.27543Keywords:
Zoonosis; Mycosis; Radiography; Canine.Abstract
Sporotrichosis is a zoonotic mycosis caused by the dimorphic fungus Sporothrix spp. In dogs, is a disease characterized by cutaneous and lymphocutaneous lesions, whereas the osteoarticular form is rare. This article describes a case of polyostoic hematogenous osteomyelitis by Sporothrix spp. The patient, a female dog, of mixed breed, arrieved for the radiographic examination with chronic lameness. The radiographic images showed agressive bone lesions in the right humerus, femur, radioulna and tibia-fibula, from where materials were collected for microbiological culture that showed the presence of Sporothrix spp. The patient was treated for 120 days with itraconazole, 10 mg/kg/day, orally, in association with potassium iodide, 5 mg/kg/twice a day, orally. Radiographic follow-up was performed 30, 90 and 270 days after the start of treatment. There was improvement in radiographic findings, but without complete resolution. This study warns that bone sporotrichosis should be included in the list of differential diagnoses of agressive polyostotic bone lesions associated with chronic lameness, especially in endemic regions. The radiographic examination was effective and very important in the identification and description of the sites and type of lesions of bone sporotrichosis.
References
Barros, M. B. L., Schubach, T. P., Coll, J. O., Gremimão, I. D., Wanke, B. & Schubach, A. (2010) Esporotricose: a evolução e os desafios de uma epidemia. Revista Panamericana de Salud Pública, 27(6), 455-460.
Bastos, M. B. L., Schubach, A. O., Valle, A. C. F., Galhardo, M. C. G, Conceição-Silva, F., Schubach, TMP, Reis, R. S, Wanke, B., Marzochi, K. B. F. & Conceição, M. J. (2004). Cat-Transmitted Sporotrichosis Epidemic in Rio de Janeiro, Brazil: Description of a Series of Cases. Clinical Infectious Diseases, 38, 529-535.
Brum, L. C., Conceição, L. G., Ribeiro, V. M. & Haddad-Junior, V. (2007). Principais dermatoses zoonóticas de cães e gatos. Clínica Veterinária, 69(7), 29-46.
Crothers, S. L., White, S. D., Ihrke, P. J. & Affolter, V. K. (2009). Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007). Veterinary Dermatology, 20(4), 249-259.
Diaz, I. A. C. (1989). Epidemiology of sporotrichosis in Latin America. Micopathologia, 6, 108-113.
Faria, R. O. (2015). Fungos dimórficos e relacionados com micoses profundas. In: Jericó, M. M., Neto, J. P.A. & Kogika, M.M. (1 ed). Tratado de medicina interna de cães e gatos. Roca, Rio de Janeiro, 2395-2419.
Farias, M. R., Assunção, D. L., Duarte, G., Vandresen, G., Werner, J., & Tasqueti, U. (2015). Canine bone sporotrichosis: a case report. Semina: Ciências agrárias, 36(3), 1445-1450.
Gremião, I. D. F., Menezes, R. C., Schubach, T. M. P., Figueiredo, A. B. F., Cavalcanti, M. C. H. & Pereira, S. A. (2015). Feline sporotrichosis: epidemiological and clinical aspects. Medical Micology, 53, 15-21.
Lima, T. B., Leal, L. M., Morato, G. O., Marinho, P. V. T., Moraes, P. C. & Minto, B. W. (2013). Osteomielite fúngica em fratura de tíbia de cão: relato de caso. Revista brasileira de Ciência Veterinária, 20(3), 132-136.
López-Romero, E., Reyes-Montes, M. R., Pérez-Torres, A., Ruiz-Baca, E., Villagómez-Castro, J. C., Mora-Montes, H. M., Flores-Carreón, A. & Toriello, C. (2011). Sporothrix Schenckii complex and sporotrichosis, an emerging health problem. Future Microbiology, 6(1), 85-102.
Madrid, I. M., Xavier, M. O., Mattei, A. S., Carapeto, L. P., Antunes, T. A., Santos-Júnior, R., Nobre, M. O. & Meireles, M. C. A. (2007). Esporotricose óssea e cutânea em canino. Brazilian Journal of Veterinary Research and Animal Science., São Paulo, 44(6), 441-443.
Olivera, M. M. E., Almeida-Paes, R., Muniz, M. M., Gutierrez-Galhardo, M. C. & Zancope-Oliveira, R. M. (2011). Phenotypic and molecular identification of Sporothrix isolates from na epidemic área of sporotrichosis in Brazil. Mycopathologia, 172(4), 257-267.
Poester, V. R., Mattei, A. S., Madrid, I. M., Pereira, J. T. B., Klafke, G. B., Sanchotene, K. O., Brandolt, T. M. & Xavier, M. O. (2018). Sporotrichosis in Southern Brazil, towards an epidemic? Zoonoses Public Health, 1-7.
Ramos, A. C. M. O., Oliveira, I. V. P, Reis-Lima, R. K., De-Paula, V. V. & Filgueira, K. D. (2017). Zoonotic transmission of canine sporotrichosis in northeastern Brazil. Acta Veterinaria Brasilica, 79-84.
Schubach, T. M. P., Schubach, A. O., Cuzzi-Maya, T., Okamoto, T., Reis, R. S., Monteiro, P. C. F., Gutierrez-Galhardo, M. C. & Wanke, B. (2003). Pathology of sporotrichosis in 10 cats in Rio de Janeiro. Veterinary Record, 152, 172-175.
Schubach, T. M. P., Schubach, A., Okamoto, T., Barros, M. B. L., Figueiredo, F. B., Cuzzi, T., Pereira, S. A.; Santos, I. B., Paes, R. A., Leme, R. P. & Wanke, B. (2006). Canine sporotrichosis in Rio de Janeiro, Brazil: clinical presentation, laboratory diagnosis and therapeutic response in 44 cases (1998-2003). Medical Mycology, 44(1), 87-92.
Schubach, A., Barros, M. B. & Wanke, B. (2008). Epidemic sporotrichosis. Current Opinion in Infectious Diseases, 21, 129-133.
Sykes, J. E., Torres, S. M., Armstrong, P. J. & Lindeman, C. J. (2001). Itraconazole for treatment of sporotrichosis in a dog residing on a Christmas tree farm. Journal of the American Veterinary Medical Association, 218(9), 1440-1443.
Thrall, D. E. Radiographic features of bone tumors and bone infections in dogs and cats. (2018). In: Thrall, D. E. (7 ed). Textbook of veterinary diagnostic radiology. Elsevier, Saint Louis, 390-402.
Viana, P. G., Figueiredo, A. B. F., Gremião, I. D. F., Miranda, L. H. M., Antonio, I. M. S., Boechat, J. S., Machado, A. C. S., Oliveira, M. M. E. & Pereira, S. A. (2018). Successful Treatment of Canine Sporotrichosis with Terbinafine: Case Reports and Literature Review. Mycopathologia, 183, 471-478.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Mariana Wilhelm Magnabosco; Vittória Bassi das Neves; Patrícia Silva Vives; Angelita Reis Gomes; Guilherme Albuquerque de Oliveira Cavalcanti
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
