Applicability of collagen biostimulators (poly-l-lactic acid and calcium hydroxyapatite) in dermal filler in off-face areas of the body

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.31181

Keywords:

Collagen biostimulators; Calcium hydroxyapatite; Poly-L-lactic acid.

Abstract

This article aims to present an integrative literature review, in which it evaluates the clinical evidence of the use of collagen biostimulators for body harmonization and if there is a recommendation for the application of the product, because in the current context, biostimulators act in body rejuvenation with the purpose of harmonizing it. This is a study carried out through the MEDLINE/PubMed and ScienceDirect databases, using the following Health Science Descriptors (DeCS) in English and Portuguese: body rejuvenation, body biostimulators, dermal fillers, body contouring, calcium hydroxyapatite, poly-L-lactic acid and its combinations, refining the findings with the Boolean operator AND. A 10-year time record was taken into account with publications in the period from 2012 to 2022, clinical studies in which they had in the abstract information that covered the objective of this study. The selected studies present satisfactory results with biostimulators in off-face regions of the body, being a safe and effective practice to treat sagging and firmness of the skin, in addition to obtaining volumization and improvement in the skin's body contours. Although studies highlight promising results in body areas, more scientific data are lacking on the use of these products in these regions.

References

Beylot, C. (2019). Vieillissement cutané – Vieillissement facial global: orientation thérapeutique. Annales de dermatologie et de venereologie, 146(1), 41–74.

Brierley, M.-E., Brooks, K. R., Mond, J., Stevenson, R. J., & Stephen, I. D. (2016). The body and the beautiful: Health, attractiveness and body composition in men’s and women’s bodies. PloS One, 11(6), e0156722.

Carruthers, J., Burgess, C., Day, D., Fabi, S. G., Goldie, K., Kerscher, M., Nikolis, A., Pavicic, T., Rho, N.-K., Rzany, B., Sattler, G., Sattler, S., Seo, K., Werschler, W. P., & Carruthers, A. (2016). Consensus recommendations for combined aesthetic interventions in the face using botulinum toxin, fillers, and energy-based devices. Dermatologic Surgery, 42(5), 586–597.

Chaudhary, M., Khan, A., & Gupta, M. (2020). Skin ageing: Pathophysiology and current market treatment approaches. Current Aging Science, 13(1), 22–30.

Cogorno Wasylkowski, V. (2015). Body vectoring technique with Radiesse (®) for tightening of the abdomen, thighs, and brachial zone. Clinical, Cosmetic and Investigational Dermatology, 8, 267–273.

Coleman, K. M., & Lawrence, N. (2017). Male body contouring. Dermatologic Surgery, 43 Suppl 2(2), S188–S193.

De Almeida, A. T., Figueredo, V., da Cunha, A. L. G., Casabona, G., Costa de Faria, J. R., Alves, E. V., Sato, M., Branco, A., Guarnieri, C., & Palermo, E. (2019). Consensus recommendations for the use of hyperdiluted calcium hydroxyapatite (radiesse) as a face and body biostimulatory agent. Plastic and Reconstructive Surgery. Global Open, 7(3), e2160.

De Freitas, C. C. P. E. C. (2013). Metodologia do Trabalho Científico: Métodos e Técnicas da Pesquisa e do Trabalho Acadêmico - 2a Edição. Editora Feevale.

De Oliveira, C. S. F. P., da Silva Almeida, T. J., de Oliveira Martins, L., Sorpreso, L. A. T., & Finck, N. S. (2021). Hidroxiapatita de cálcio: uma revisão quanto à eficacia, segurança e imaginologia quando usado como preenchedor e como bioestimulador. Portal REDIB Red Iberoamericanos.

Fabi, S. G., Burgess, C., Carruthers, A., Carruthers, J., Day, D., Goldie, K., Kerscher, M., Nikolis, A., Pavicic, T., Rho, N.-K., Rzany, B., Sattler, S., Seo, K., Werschler, W. P., & Sattler, G. (2016). Consensus recommendations for combined aesthetic interventions using botulinum toxin, fillers, and microfocused ultrasound in the neck, décolletage, hands, and other areas of the body. Dermatologic Surgery, 42(10), 1199–1208.

Fabi, S., Pavicic, T., Braz, A., Green, J. B., Seo, K., & an Loghem, J. A. (2017). Combined aesthetic interventions for prevention of facial ageing, and restoration and beautification of face and body. Clinical, Cosmetic and Investigational Dermatology, 10, 423–429.

Fitzgerald, R., Bass, L. M., Goldberg, D. J., Graivier, M. H., & Lorenc, Z. P. (2018). Physiochemical characteristics of poly-L-lactic acid (PLLA). Aesthetic Surgery Journal, 38(suppl_1), S13–S17.

Goldie, K., Peeters, W., Alghoul, M., Butterwick, K., Casabona, G., Chao, Y. Y. Y., Costa, J., Eviatar, J., Fabi, S. G., Lupo, M., Sattler, G., Waldorf, H., Yutskovskaya, Y., & Lorenc, P. (2018). Global consensus guidelines for the injection of diluted and hyperdiluted calcium hydroxylapatite for skin tightening. Dermatologic Surgery, 44 Suppl 1, S32–S41.

Krüger, N., Lübberding, S., & Sattler, G. (2015). Körperkonturierung. Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete, 66(10), 772–780.

Krutmann, J., Bouloc, A., Sore, G., Bernard, B. A., & Passeron, T. (2017). The skin aging exposome. Journal of Dermatological Science, 85(3), 152–161.

Lin, M. J., Dubin, D. P., & Khorasani, H. (2020). Poly-l-lactic acid for minimally invasive gluteal augmentation. Dermatologic Surgery, 46(3), 386–394.

Mora Huertas, A. C., Schmelzer, C. E. H., Hoehenwarter, W., Heyroth, F., & Heinz, A. (2016). Molecular-level insights into aging processes of skin elastin. Biochimie, 128–129, 163–173.

Nikolis, A., Avelar, L. E., & Enright, K. M. (2021). Evaluation of cannula safety in injection of poly-L-lactic acid. Clinical, Cosmetic and Investigational Dermatology, 14, 615–622.

Pulit, S. L., Karaderi, T., & Lindgren, C. M. (2017). Sexual dimorphisms in genetic loci linked to body fat distribution. Bioscience Reports, 37(1), BSR20160184.

Ribas, T. N. F., & Moura, J. B. F. (2021). Relatos de profissionais sobre intercorrências em tratamentos estéticos corporais. Research, Society and Development, 10(16), e133101623507.

Sadick, N. S. (2018). The pathophysiology of the male aging face and body. Dermatologic Clinics, 36(1), 1–4.

Shridharani, S. M., Tisch, G. M., Ebersole, T. G., Moak, T. N., & Edwartz, C. (2021). Clinical experience of poly-L-lactic acid injections for body contouring treatment. Journal of Cosmetic Dermatology, 20(6), 1655–1662.

Sorg, O., Kaya, G., & Saurat, J.-H. (2017). Index. Em Dermatologie et Infections Sexuellement Transmissibles (p. 1215–1245). Elsevier.

Van Loghem, J., Yutskovskaya, Y. A., & Philip Werschler, W. (2015). Calcium hydroxylapatite: over a decade of clinical experience. The Journal of Clinical and Aesthetic Dermatology, 8(1), 38–49.

Yutskovskaya, Y. A., & Kogan, E. A. (2017). Improved neocollagenesis and skin mechanical properties after injection of diluted calcium hydroxylapatite in the neck and décolletage: A pilot study. Journal of Drugs in Dermatology: JDD, 16(1), 68–74.

Zhang, S., & Duan, E. (2018). Fighting against skin aging: The way from bench to bedside: The way from bench to bedside. Cell Transplantation, 27(5), 729–738.

Published

26/06/2022

How to Cite

NOGUEIRA, I. C. da C.; SILVA, N. C. S. da. Applicability of collagen biostimulators (poly-l-lactic acid and calcium hydroxyapatite) in dermal filler in off-face areas of the body. Research, Society and Development, [S. l.], v. 11, n. 8, p. e47411831181, 2022. DOI: 10.33448/rsd-v11i8.31181. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/31181. Acesso em: 25 apr. 2024.

Issue

Section

Review Article