An analogy in the use of metformin, clomiphene citrate and letrozole: in the treatment of polycystic ovary syndrome
DOI:
https://doi.org/10.33448/rsd-v11i13.35520Keywords:
Metformin; Clomiphene Citrate; Letrozole; Obesity; Polycystic ovary syndrome.Abstract
Polycystic ovary syndrome (PCOS) is one of the most common clinical conditions among endocrine disorders that affect women of reproductive age, accounting for about 80% of cases of anovulatory infertility. Objective to carry out a literature review on the use of metformin in the treatment of women with PCOS, making an analogy in the use of metformin, clomiphene citrate and letrozole. Methodology: The study is an integrated review of the literature as a reference for articles from the years 2013 to 2020 carried out in the databases: Medline, Lilacs, Scielo. Identified on 80 articles, used from 20 in the elaboration of the work. Results: Metformin was shown to be effective as a combination therapy with letrozole in the treatment of PCOS, but there was no consensus on its use as monotherapy.
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Copyright (c) 2022 Antônia Eliene da Silva Rodrigues; Omero Martins Rodrigues Junior; Roseane da Silva Oliveira; Marlene de Souza Andrade; Rosane da Costa Alho; Regiana Almeida da Gama; Maria Regina de Souza Romão; Odirene Railane Ferreira do Carmo
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