Antifungal activity of essential oils against Candida albicans strain

Authors

DOI:

https://doi.org/10.33448/rsd-v11i14.35696

Keywords:

Essential oils; Antifungal activity; Fungal pharmacoresistance; Candida albicans.

Abstract

Resistance to antifungal agents is a problem in global health, and it is necessary to seek alternatives for control and treatment. There are scientific reports that show the potential for antifungal action of essential oils. The main objective of the research was to evaluate the sensitivity profile of C. albicans through the use of essential oils. It was an experimental study with a quantitative approach of the antifungal action of essential oils against the C. albicans ATCC strain, obtained commercially. The selection of essential oils was carried out through the recommendations of the Brazilian Pharmacopoeia. The strain was kept in successive repetitions in TSA culture medium, until use in the susceptibility tests. The antifungal activity of the essential oils was performed by the technique of diffusion in agar in wells. It was found that all essential oils were able to sensitize the C. albicans strain. With emphasis on C. cassia with formation of an inhibition halo of 40mm in diameter and lower potential for E. globulus with an inhibition halo of 12mm. The present study showed that the essential oils tested have antifungal properties on the C. albicans strain, however, with different susceptibility profiles. In addition, the data obtained allow expanding the knowledge about products of plant origin with antifungal potential. It is suggested that further research should be carried out in this line of investigation with the purpose of identifying other essential oils with this action and their phytoconstituents.

References

Abdellah, F., Boubakeur, B., Ayad, N., Boukraa, L., Hammoudi, S. M., Abdelhak, & B., Benaraba, R. (2021). Chemical Composition and Biological Activities of Eugenia caryophyllata Thunb Essential Oil. Asian Journal of Applied Chemistry Research, 9(4), .51-62. DOI:10.9734/ajacr/2021/v9i430224.

Aldholmi, M., Marchand, P., Garnier, I. O., Pape, P. L., & Ganesan, A. A. (2019). Decade of Antifungal Leads from Natural Products: 2010–2019. Pharmaceuticals, 12(182), 182. DOI:10.3390/ph12040182

Alves, E. G., Vinholis, A. H. C., Casemiro, L. A., Furtado, N. A. J. C., Silva, M. L. A., Cunha, W. R., & Martins, C. H. G. (2008). Estudo comparativo de técnicas de screening para avaliação da atividade anti-bacteriana de extratos brutos de espécies vegetais e de substâncias puras. Química nova, 31(5), 1224-1229. DOI: 10.1590/S0100-40422008000500052.

Alves, M., Gonçalves, M. J., Zuzarte, M., Silva, J. M. A., Cavaleiro, C., Cruz, M. T., & Salgueiro, L. (2019). Unveiling the Antifungal Potential of Two Iberian ThymeEssential Oils: Effect on C. albicans Germ Tube and Preformed Biofilms. Front. Pharmacol., 10, 446. DOI: 10.3389/fphar.2019.00446.

Agência Nacional de Vigilância Sanitária - ANVISA. (2019). Farmacopeia Brasileira, v. 1. (6. ed.). Brasilia, 903p.

Ayres, M. J. N., Chávez, M. J. H., Carnero, L. C. G., Hernández, D. G. A., Pérez, N. E. L., Mata, E. E., Duncker, I. M. Franco, B., & Montes, H. M. M. (2019). Differential recognition of Candida tropicalis,Candida guilliermondii, Candida krusei, and Candida auris by human innate immune cells. Infection and Drug Resistance, 12, 783-794. DOI: 10.2147/IDR.S197531.

Augostine, C. R., & Avery, S. V. (2022). Discovery of Natural Products With Antifungal Potential Through Combinatorial Synergy. Front. Microbiol., 13(866840), 866840. DOI: 10.3389/fmicb.2022.866840.

Ayres, M., Ayres Júnior, M., Ayres, D. L., & Santos, A. D. A. (2007). BioEstat: aplicações estatísticas nas áreas das ciências Bio-médicas. Belém: CNPQ, 364p.

Aziz, Z. A. A., Ahmad, A., Setapar, S. H. M., Karakucuk, A., Azim, M. M., Rafatullah, M. Ganash, M., Kamal, M. A., & Ashraf, G. M. D. (2018). Essential Oils: Extraction Techniques, Pharmaceutical And Therapeutic Potential - A Review. Curr. DrugMetab., 19(13), 1100-1110. DOI:10.2174/1389200219666180723144850.

Bakht, J.,Farid, S., Iqbal, A., & Shafi, M. (2018). Impact of different solvent extracts from leaves and fruits of Eucalyptus globulus on growth of different bacteria and fungi. Pak JPharm Sci., 31(5), 1845-1852. PMID: 30150179.

Balloux, F., & Van Dorp, L. (2017). Q&A: What are pathogens, and what have they done to andfor us?. BMC Biol., 14(1), 1-6. DOI:10.1186/s12915-017-0433-z.

Benoutman, A., Erbiai, E. H., Edderdaki, F. Z., Cherif, E. K., Saidi, R., Lamrani, Z., Pintado, M., Pinto, E., Da Silva, J. C. G. E., & Maouni, A. (2022). Phytochemical Composition, Antioxidant and Antifungal Activity of Thymus capitatus, a Medicinal Plant Collected from Northern Morocco. Antibiotics, 11, 1-18. DOI:10.3390/antibiotics11050681.

Bhattacharya, S., Tia, S . S., & Fries, B. C. (2020). Candidiasis and Mechanisms of Antifungal Resistance. Antibiotics, 9(6), 1-19. DOI:10.3390/antibiotics9060312.

Brochot, A., Guilbot, A., Haddioui, L., & Christine Roques. (2017). Antibacterial, antifungal, and antiviral effects of three essential oil blends. antifungal, and antiviral effects ofthree essential oil blends. MicrobiologyOpen, 6(4), e00459. DOI:10.1002/mbo3.459.

Byrd, A. L., Belkaid, Y., & Segrem J. A. (2018). The human skin microbiome. Nat. Rev. Microbiol., 16(3), 143-155. DOI: 10.1038/nrmicro.2017.157.

Butzge, J. C., Ferrão, S. K., Mezzomo, F., Calil, L. M., Mezzari, A., Limberguer, R. P., & Apel, M. A. (2020). Antifungal activity of essential oils from Cinnamomum cassia, Myristica fragrans and Syzygium aromaticum against Rhodotorula mucilaginosa. Drug Analytical Research, 4(2), DOI: 10.22456/2527-2616.104615.

Chaabane, F., Graf, A., Jequier, L., & Coste, A. T. (2019). Review on Antifungal Resistance Mechanisms in the Emerging Pathogen Candida auris. Frontiers in Microbiology, 10, 2788. DOI: 10.3389/fmicb.2019.02788.

Chernov, V. M., Chernova, O. A., Mouzykantov, A. A., Lopukhov, L. L., & Aminov, R. I. (2019). Omics of antimicrobials and antimicrobial resistance. Expert Opinion on Drug Discover, 14(5),1-15. DOI: 10.1080/17460441.2019.1588880.

De Clerck, C., Dal Maso, S., Parisi, O., Dresen, F., Zhiri, A., & Jijakli, M. H. (2020). Screening of Antifungal and Antibacterial Activity of 90 Commercial Essential Oils against 10 Pathogens of Agronomical Importance. Foods., 7(9), 1-11. DOI:10.3390/foods9101418.

Cano, C. E., Castro, M. A. A., Castellanos, L. M., Triana, A. G., & Ochoa, L. H. (2017). Antifungal activity of microcapsulated clove (Eugenia caryophyllata) and Mexican oregano (Lippia berlandieri) essential oils against Fusarium oxysporum. Journal of Microbiology and Biochemical Technology, 9, 567-571. DOI: 10.4172/1948-5948.1000342.

Clinical Laboratory Standards Institute - CLSI. (2019). Performance standardsfor antimicrobial susceptibility testing: twenty-first informational supplement. NCCLSdocument M100-521, 34(1),1-13.

D'agostino, M., Tesse, N., Frippiat, J. P., Machouart, M., & Debourgogne, A. (2019). Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties. Molecules, 24(20), 3713. DOI: 10.3390/molecules24203713.

Da Rocha, W. R. V., Nunes, L. E., Neves, M. L. R., Ximenes, E. C. P. De A., & Albuquerque, M. C. P. De A. (2021). Gênero Candida - Fatores de virulência, Epidemiologia,Candidíase e Mecanismos de resistência. Research, Society and Development, 10(4), e43910414283. DOI: 10.33448/rsd-v10i4.14283.

Da Silva, L. L., De Almeida, R., Vericímo, M. A., De Macedo, H. W., & Castro, H. C. (2019). Atividades terapêuticas do óleo essencial de melaleuca (Melaleuca alternifolia) uma revisão de literatura. Braz. J. Hea. Rev., 2(6), 6011-6021. DOI: 10.34119/bjhrv2n6-094.

Da Silva, R. A., De Oliveira, B. N. L., Da Silva , L. P. A., Oliveira, M . A., & Chaves, G. C. (2020). Resistência a Antimicrobianos: a formulação da resposta no âmbito da saúdeglobal. Saúde Debate, 44(124), 607-623. DOI:10.1590/0103-1104202012602.

Da Silva, R.A.., Antonieti, F.M.P.M., Röder, D.V. De B., & Pedroso, R. dos S. (2021). Essential oils of melaleuca, citrus, cupressus, and litsea for the management of infections caused by candida species: a systematic review. Pharmaceutics, 13, 1-18. DOI:0.3390/pharmaceutics13101700.

De Araújo, I. M., Lopes, L. P., & Da Cruz, C. M. (2020). Caracterização sistemática da respostaimune à infecção por Candida. Braz. J. Hea. Rev., 3(2), 3788-3803, 2020. DOI:10.34119/bjhrv3n2-203

De Oliveira, S. C., & Rodrigues, A. G. (2020). Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal. Microorganisms, 8, 1-19. DOI:10.3390/microorganisms8020154.

Dhingra, S., Rahman, N. A. A., Peile, E., Rahman, M., Sartelli, M., Hassali, M. A., Islam, T., Islam, S., & Haque, M. (2020). Microbial Resistance Movements: An Overview of Global Public Health Threats Posed by Antimicrobial Resistance, and How Best to Counter. Front. Public Health.8, 1-22. DOI:10.3389/fpubh.2020.535668.

Felipe, L. De O., Júnior, W. F. Da S., De Araújo, K. C., & Fabrino, D. L. (2018). Lactoferrin, chitosan and Melaleuca alternifolia-natural products that show promise in candidiasis treatment. Braz J. Microbiol., 49(2), 212-219. DOI:10.1016/j.bjm.2017.05.008.

Ferreira, V. M., Rossiter, L. N. V., Aragão, N. F. F., Pinto, O. A., Santos, P. M., Cardoso, P. H. A., Cerqueira, T. B., Fernandino, D. M., & Rocha, G. M. (2017). Infecções comunitárias do trato urinário em Divinópolis, MG: avaliação do perfil de resistência bacteriana e do manejo clínico. Rev. Bras Med Fam Comunidade, 12(39), 1-13. DOI:10.5712/rbmfc12(39)1553.

Feyaerts, A. F., Mathé, L., Luyten, W., & Van Djick, P. (2018). Comparison between the vapor-phase-mediated anti-Candida activity of conventional and organic essential oils. Nat.Volatiles & Essent. Oils, 5(1), 1-6. ISSN: 2148-9637.

Feyaerts, A. F., Mathé, L., Luyten, W., De Graeve, S., Van Dyck, K., Broekx, L., & Van Dijck, P. (2018). Essential oils and their components are a class of antifungalswith potent vapour-phase-mediated anti-Candida activity. Sci Rep., 8,. 1-10. DOI:10.1038/s41598-018-22395-6.

Figueiredo, A. R., Da Silva, L. R., & De Morais, L. A. S. (2021). Bioatividade do óleo essencial de Eugenia caryophyllus sobre Cladosporium herbarum, agente etiológico daverrugose em maracujá. Scientia Plena, 17(2), 1-8. DOI:10.14808/sci.plena.2021.020201.

Figueiredo, C. S. S. E S., De Oliveira, P. V., Saminez, W. F. De S., Diniz, R. M.,Rodrigues, J. F. S., Da Silva, M. S. M., Da Silva, L. C. N., & Grisotto, M. A. G. (2017). Óleo essencial da Canela (Cinamaldeído) e suas aplicações biológicas. Rev. Investig,Bioméd., 9(2), 192-197. DOI: 10.24863/rib.v9i2.143.

Fisher, M. C., Izquierdo, A. A., Berman, J., Bicanic, T., Bignell, E. M., Bowyer, P., Bromley, M., Bruggemann, R., Garber, G., Cornely, O. A., Gurr, S. J., Harrison, T. S., Kuijper, E., Rodes, J., Sheppard, D. C., Warris, A., White, P. L., Xu, J., Zwaan, B., & Verweij, P. E. (2022). Tackling the emerging threat ofantifungal resistance to human health. Nat. Rev. Microbiol, p. 1- 15. DOI: 10.1038/s41579-022-00720-1.

Francisconi, R. S., Huacho, P. M. M., Tonone, C. C., Bordini, E. A. F., Correia, M. F., Sardi, J. De C. O., & Spolidorio, D. M. P. (2020). Antibiofilm efficacy of tea tree oil and of its main component terpinen-4-ol against Candida albicans. Braz. Oral Res.,34, 1-9. DOI: 10.1590/1807-3107bor-2020.vol34.0050.

Gioppo, A., Zancanaro,V., & Bellaver, E. H. (2019). Atividade antibacteriana do óleo essencial de Melaleuca alternifolia frente a isolados multirresistentes produtores de ESBL eKPC causadores de infecções hospitalares. Rev. Biotemas, 32(3), 35-42. DOI:10.5007/2175-7925.2019v32n3p35.

Grove, D.C., & Randall, W.A. (1955). Assay methods of antibiotics: A laboratory manual. (2.ed.) Nova York: Medical Encyclopedia Inc, 238p.

Guoruoluo, Y., Zhou, H., Zhou, J., Zhao, H., Aisa, H. A., & Yao, G. (2017). Isolation and Characterization of Sesquiterpenoids from Cassia Buds and Their Antimicrobial Activities. J.Agric. Food Chem., 66(28), 5614-5619. DOI:10.1021/acs.jafc.7b01294.

Hameed, S., Hans, S., Monasky, R., Thangamani, S., & Fatima, Z. (2021). Understanding Human Microbiota Offers Novel and Promising Therapeutic Options against Candida Infections. Pathogens, 10, 1-15. DOI:10.3390/pathogens10020183.

Han, H., & Parke, T. L. (2017). Anti-inflammatory activity of clove (Eugenia caryophyllata) essential oil in human dermal fibroblasts. Pharm Biol, 55(1), 1619-1622. DOI:10.1080/13880209.2017.1314513

Haque, M., Mckimm, J., Sartelli, M., Dhingra, S., Labricciosa, F. M., Islam, S., Jahan, D., Nusrat, T., Chowdhury, T. S., Coccolini, F., Iskandar, K., Catena, F., & Charan, J. (2020). Strategies to Prevent Healthcare- Associated Infections: A Narrative Overview. Risk Manag Healthc Policy, 13, 1765-1780. DOI:10.2147/RMHP.S269315.

Heard, S. C., Wu, G., & Winter, J. M. (2021). Antifungal natural products. Current Opinion in Biotechnology, 69, 232–241. DOI:10.1016/j.copbio.2021.02.001.

Helal, I. M., El Bessoumy, A., Al Bataineh, E., Joseph, M. R. P., Rajagopalan, P., Chandramoorthy, H. C., Ahmed, S. B. H. (2019). Antimicrobial Efficiency of Essential Oils from Traditional Medicinal Plants of Asir Region, Saudi Arabia,over Drug Resistant Isolates. Biomed Res Int., v.2019, n. 8928306, p. 1-9. DOI:10.1155/2019/8928306.

Höfling, J. F., Anibal, P. C., Pereda, G. A. O., Peixoto, I. A. T., Furletti, V. F., Foglio, M. A., & Gonçalves, R. B. (2010). Antimicrobial potential of some plant extracts against Candida species. Brazilian Journal of Biology, 70(4), 1065- 1068. DOI:10.1590/S1519-69842010000500022.

Ingok, A. M., Devecioglu, D., Dikmetas, D. N., Guler, F. K., & Capanoglu, E. (2020). Antibacterial, Antifungal, Antimycotoxigenic, and Antioxidant Activities of Essential Oils:An Updated Review. Molecules, 25, 1-49. DOI: 10.3390/molecules25204711.

Iseppi, R., Mariani, M., Condó, C., Sabia, C., & Mess, P. (2021). Essential Oils: A Natural Weapon against Antibiotic-Resistant Bacteria Responsible for Nosocomial InfectionsMess. Antibiotics, 10, 1-14. DOI:10.3390/antibiotics10040417.

Khosravi, A. R., Sharifzadeh, A., Nikaein, D., Almaie, Z., & Nasrabadi, H. G. (2018). Chemical composition, antioxidant activity and antifungal effects of five Iranian essential oilsagainst Candida strains isolated from urine samples. J. Mycol Med., 28(2), 355-360. DOI: 10.1016/j.mycmed.2018.01.005.

Lakatos, E. M., & Marconi, M. de A. (2021). Metodologia científica. (9. ed.). Atlas.

Lara, M. F. G., & Zeichner, L. O. (2020). Invasive Candidiasis. Semin. Respir. Crit. Care Med., 41(1), 003-012. DOI: 10.1055/s-0040-1701215.

Li, F. S., & Weng, J. K. (2017). Demystifying traditional herbal medicine with modern approach. Nat.Plants, 3, 17109. DOI:10.1038/nplants.2017.109.

Lindberg, E., Hammarström, H., Ataollahy, N., & Kondor, N. (2019). Species distribution and antifungal drug susceptibilities of yeasts isolated from the blood samples of patients with candidemia. Scientific Reports, 9(3838), 1-6. DOI:10.1038/s41598-019-40280-8.

Liu, Q., Meng, X., Li, Y., Zhao, C. N., Tang, G. Y., & Li, H. B. (2017). Antibacterial and Antifungal Activities of Spices. Int. J. Mol. Sci., 18(6), 1-62. DOI:10.3390/ijms18061283.

Liu, H., Geng, M., Qin, Y., Xiao, Y., & Li, M. (2019). Characterization of the complete chloroplastgenome of medicinal tea tree (Melaleuca alternifolia). Mitochondrial DNA B Resour, 4(2), 3307-3308. DOI:10.1080/23802359.2019.1673246.

Lopes, J. P., & Lionakis, M. (2021). Pathogenesis and virulence of Candida albicans. Virulence, 13(1), 89-121. DOI: 10.1080/21505594.2021.2019950.

Marchese, A., Barbieri, R., Coppo, E., Orlan, I. E., Daglia, M., Nabavi, S. F., Izadi, M., Abdollahi, M., Nabavi, S, M., & Ajami, M. (2017). Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint. Crit. Rev. Microbiol., 43(6), 1-22. DOI: 10.1080/1040841X.2017.1295225.

Mcewen, S. A., & Collignon, P. J. (2018). Antimicrobial Resistance: a One Health Perspective, Microbiol. Spectr., 6(2), 1-26. DOI:10.1128/microbiolspec.ARBA-0009-2017.

Monteiro, R. F. Dos S., Santos, V. R. R. Dos, Ferreira, A. A. C. T., & De Abreu, J. R. G. (2020). O uso indiscriminado de antimicrobianos para o desenvolvimento de micro-organismos resistentes. Revista Eletrônica Acervo Saúde, v. sup, 53, p. 1- 10. DOI: 10.25248/reas.e3597.2020.

Nakaom A. K., Maekawa, L. E., Sousa, N. J. A., Da Mata, P. S., Nakae, M. Y., & Paiva, J. C. M. (2020). Atividade antimicrobiana dos óleos de gengibre e melaleuca frente Candida albicans. Revista Ciêntifica UMC, 5(2), 1-12. ISSN:2525-5250.

Nami, S., Maleki, A. A., Morovati, H., & Maleki, L. A. (2019). Current antifungal drugs andimmunotherapeutic approaches as promising strategies to treatment of fungal diseases. Biomedicine & Pharmacotherapy, 110, 857-868. DOI:10.1016/j.biopha.2018.12.009.

Nazzaro, F., Fratianni, F., Coppola, R., & De Feo,V. (2017). Essential Oils and Antifungal Activity. Pharmaceuticals, 10(4), 1-20. DOI: 10.3390/ph10040086.

Nisar, M. F., Khadim, M., Rafiq, M., Chen, J., Yang, Y., & Wan, C. C. (2021). Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review. OxidMed Cell Longev, 3, 1-14. DOI:1155/2021/2497354.

Paludo, R. M., & Marin, D. (2018). Relação entre candidíase de repetição, disbiose intestinal e suplementação com probióticos: uma revisão. Destaques Acadêmicos, 10(3), 46-57. DOI: 10.22410/issn.2176-3070.v10i3a2018.1745.

Pappas, P. G., Lionakis, M S., Arendrup, M C., Zeichner, L. O., & Kullberg, B. J. (2018). Invasive candidiasis. Nat. Rev. Dis. Primers, 4(18026) 1- 20. DOI:10.1038/nrdp.2018.26.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da Pesquisa Científica. Santa Maria: UFSM, NTE, 119f.

Pereira, R., Fontenelle, R. O. dos S., De Brito, E. H. S., & De Morais, S. M. (2021). Biofilm of Candida albicans: formation, regulation and resistance. J. Appl. Microbiol., 131(1), 11-22. 2021. DOI:10.1111/jam.14949.

Pootong, A., Norrapong, B., & Cowawintaweewat, S. (2017). Antifungal activity of cinnamaldehyde against Candida albicans. J. Trop. Med. Public Health 48(1), 150-158. PMID: 29644831

Quatrin, P. M., Verdi, C. M., De Souza, M. E., De Godoi, S. N., Klein, B., Gundel, A., Wagner, R., Vaucher, R. De A., Ourique, A. F., & Santos, R. C. V. (2017). Antimicrobial and antibiofilm activities of nanoemulsions containing Eucalyptus globulus oil against Pseudomonas aeruginosa and Candida spp. Microbial Pathogenesis, 112, 230– 242. DOI: 10.1016/j.micpath.2017.09.062.

Ramírez, Y. C. M., & Delgado, E. M. M. (2019). Eficacia antifúngica del extracto etanólico de Eucalyptus globulus sobre Candida albicans in vitro. Revista Médica de Trujilo, 14(2), 79-91. DOI: 10.17268/rmt.2019.v14i02.02.

Revie, N. M., Iyer, K. R., Robbins, N., & Cowen, L. E. (2018). Antifungal drug resistance: evolution, mechanisms and impact. Curr Opin Microbiol., 45, 70-76, 2018. DOI: 10.1016/j.mib.2018.02.005.

Rokas, A. (2022). Evolution of the human pathogenic lifestyle in fungi. Nature Microbiology, 7, 607–619. DOI: 10.1038/s41564-022-01112-0.

Santos, G. C. de O., Vasconcelos, C. C., Lopes, A. J. O., Cartágenes, M. do S. de S., Filho, A. K. D. B., do Nascimento, F. R. F., Ramos, R. M., Pires, E. R. R.B., de Andrade, M. S., Rocha, F. M. G., & Monteiro, C. de A. (2018). Candida Infections andTherapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents. Frontiers in Microbiology, 9, 1-23. DOI: 10.3389/fmicb.2018.01351.

Semnani, K., Ghahfarokhi, M. S., Afrashi, M., Fakhrali, A., & Semnani, D. (2018). Antifungal Activity of Eugenol Loaded Electrospun PAN Nanofiber Mats Against Candida albicans. Curr Drug Deliv., 15(6), 860-866. DOI:10.2174/1567201815666180226120436.

Silva, S. B., Borges, S., Ramos, O. L., Pintado, M., & Sarmento, B. (2020). The progress of essential oils as potential therapeutic agents: a review. Journal of Essential Oil Research, p. 1-17. DOI: 10.1080/10412905.2020.1746698.

Šernaitė, L., Rasiukevičiūtė, N., & Valiuškaitė, A. (2020). The Extracts of Cinnamon and Clove as Potential Biofungicides against Strawberry Grey Mould. Plants, 9(5), 1-11. DOI:10.3390/plants9050613.

Sharifi-Rad, J., Dey, A., Koirala, N., Shaheen, S., El Omari, N., Salehi, B., Goloshvili, T., Silva, N. C. C., Bouyahya, A., Vitalini, S., Varoni, E. M., Martorell, M., Abdolshahi, A.,Docea, A. O., Iritim, M.,Calina, D., Les, D., López, V., & Caruntu, C. (2021). Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits. Frontiers in Pharmacology, 12, 600139. DOI: 10.3389/fphar.2021.600139.

Sohilait, H. J., Kainama, H., & Nindatu, M. (2018). Essential Oil Components of Eugenia caryophylata Leaf from West Amboina Island. AIP Conference Proceedings, 2049(1), 020028-1-020028-7. DOI: 10.1063/1.5082433.

Šonje, M. B., Knežević, S., & Abram, M. (2020). Challenges to antimicrobial susceptibility testing of plantderived polyphenolic compounds. Arh Hig Rada Toksikol, 71, 300-311. DOI:10.2478/aiht-2020-71-3396.

Staniszewska, M. (2020). Virulence Factors in Candida species. Curr. Protein Pept. Sci., 21(3), 313-323. DOI:10.2174/1389203720666190722152415.

Sukhikh, S., Ivanova, S., Babich, O., Larina, V., Krol, O., Prosekov, A., Popov, A., & Kriger, O. (2022). Antimicrobial Screening and Fungicidal Properties of Eucalýptus globulus Ultrasonic Extracts. Plants, 11(11), 1-21. DOI:10.3390/plants11111441.

Wiederhold, N. P. (2017). Antifungal resistance: current trends and future strategies to combat. Infection and Drug Resistance, 10, 249-259. DOI: 10.2147/IDR.S124918.

Whiley, H,. Gaskin, S., Schroder, T., & Ross, K. (2017). Antifungal properties of essentialoils for improvement of indoor air quality: a review. Reviews on Environmental Health, 33(1), 63–76. DOI:10.1515/reveh-2017-0023.

Yano, J. et al. (2019). Current patient perspectives of vulvovaginal candidiasis: incidence, symptoms,management and posttreatment outcomes. BMC Women's Health. 19(48), 1-9. DOI:10.1186 / s12905-019-0748-8.

Yoon, J., & Kim, T. J., (2021). Synergistic Antifungal Activity of Magnoliae Cortex and Syzyii Flosagainst Candida albicans. J. Korean Wood Sci. Technol., 49(2), 142-153. DOI:10.5658/WOOD.2021.49.2.142.

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24/10/2022

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OLIVEIRA, A. F. M. .; SILVA, F. L. da .; SILVA, R. T. da .; MORAIS, F. M. .; SANTOS, R. R. L. dos .; SILVA, L. L. W. V. da .; OLIVEIRA, J. M. .; MORAIS, C. C. . Antifungal activity of essential oils against Candida albicans strain. Research, Society and Development, [S. l.], v. 11, n. 14, p. e04111435696, 2022. DOI: 10.33448/rsd-v11i14.35696. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/35696. Acesso em: 18 apr. 2024.

Issue

Vol. 11 No. 14

Section

Health Sciences

License

Copyright (c) 2022 Ana Florise Morais Oliveira; Francisco Laurindo da Silva; Reginara Teixeira da Silva; Francilene Maria Morais; Rodolfo Ritchelle Lima dos Santos; Laudimir Leonardo Walbert Veloso da Silva; Jonathas Morais Oliveira; Cleide Coelho Morais

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