Conservative treatment of ameloblastoma: A systematic review

Authors

DOI:

https://doi.org/10.33448/rsd-v12i11.43551

Keywords:

Ameloblastoma; Conservative treatment; Odontogenic tumor.

Abstract

Ameloblastomas are benign odontogenic tumors, yet they exhibit locally aggressive behavior and a high recurrence rate, originating from cells responsible for enamel formation during development. Due to such behavior, the clinical management and treatment of this lesion are widely discussed regarding conservative or radical approaches. This study aimed to provide evidence-based data on the choice of treatment for ameloblastoma, as well as the benefits and drawbacks of conservative treatment. The objective of this study was to furnish evidence-based information regarding the selection of treatment for ameloblastoma, including an evaluation of the advantages and disadvantages of conservative therapy. The research was executed in accordance with rigorous procedures of a systematic literature review, exclusively encompassing primary research studies. These investigations encompassed articles listed in the SciELO, BVS, and PubMed databases spanning from 2013 to 2023. Initially, 83 articles were identified, from which 25 satisfied the eligibility criteria. This investigation has discerned that the choice of treatment strategy will be contingent upon the ameloblastoma type, patient's age, lesion dimensions, aesthetic and functional impairments, and patient compliance with the chosen treatment modality. The conservative approach exhibited superior outcomes among younger patients.

References

Barros, A. V. M., Dib, C. F. L. B., Santos, K. R., Barros, M. C., Uchôa, C. P., Souza, R. C. V., Dourado, A. C. A. G., & Oliveira e Silva, E. D. (2020). Tratamento conservador de ameloblastoma sólido recidivante em paciente jovem: Relato de caso. Rev. cir. traumatol. buco-maxilo-fac, 20(1), 39–42.

Borrello, R., Bettio, E., Bacci, C., Valente, M., Sivolella, S., Mazzoleni, S., & Berengo, M. (2016). A Conservative Approach to a Peripheral Ameloblastoma. Case Rep Dent, 8254571–8254571.

Budihardja, A. S., & Lutfianto, B. (2023) A Modified Enucleation and Deflation to Treat Large Ameloblastoma in the Mandible. Case Reports in Dentistry, 2023(1), 1-5.

Carvalho e Souza, C. H., Fé, J. L. M., Sousa, L. L. A., Borba, M. S. D. C., Barros, S. S. L. V., & Lopes, M. C. A. (2015). Radical management of aggressive lesions: A case report of recurrent ameloblastoma. RGO (Porto Alegre), 63(3), 327–330.

Demir, E., & Gunhan, O. (2023). Conservative treatment of a unicystic ameloblastoma by marsupialization with a favorable response: A case report and review of the literature. Dent Res J (Isfahan), 20, 10–10.

Hammarfjord, O., Roslund, J., Abrahamsson, P., Nilsson, P., Thor, A., Magnusson, M., Kjeller, G., Englesson-Sahlström, C., Strandkvist, T., Warfvinge, G., & Krüger-Weiner, C. (2013). Surgical treatment of recurring ameloblastoma, are there options? Br J Oral Maxillofac Surg, 51(8), 762–766.

Hendra, F. N., Natsir K. D. S., Van Cann, E. M., Vet, H. C. W., Helder, M. N., & Forouzanfar, T. (2019). Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta-analysis. Oral Dis, 25(7), 1683–1696.

Hresko, A., Burtyn, O., Pavlovskiy, L., Snisarevskyi, P., Lapshyna, J., Chepurnyi, Y., Kopchak, A., Karagozoglu, K. H., & Forouzanfar, T. (2021). Controversies in ameloblastoma management: Evaluation of decision making, based on a retrospective analysis. Med Oral Patol Oral Cir Bucal, 26(2), 181–186.

Isolan, C.P., Moreira, A.G., Edges, A., Post, L. K., & Aitken-Saavedra, J. P. (2018). Successful conservative treatment of a mandibular unicystic ameloblastoma: 13-year follow-up. J Clin Exp Dent, 10(11), 1123–1126.

Kim, S.W., Jee, Y. J., Lee, D. W., & Kim, H. K. (2018). Conservative surgical treatment for ameloblastoma: A report of three cases. J Korean Assoc Oral Maxillofac Surg, 44(5), 242–247.

Laborde, A., Nicot, R., Wojcik, T., Ferri, J., & Raoul, G. (2017). Ameloblastoma of the jaws: Management and recurrence rate. Eur Ann Otorhinolaryngol Head Neck Dis, 134(1), 7–11.

Laino, L., Cicciù, M., Russo, D., & Cervino, G. (2020). Surgical Strategies for Multicystic Ameloblastoma. J Craniofac Surg, 31(2), 116–119.

Lee, S. M., Ku, J. K., Leem, D. H., Baek, J. A., & Ko, S. O. (2021). Conservative management with Carnoy’s solution in ameloblastoma involving two unerupted teeth: A report of two cases. J Korean Assoc Oral Maxillofac Surg, 47(1), 40–46.

Marimuthu, L., Kumar, S., Shenoy, V., Afradh, M., & Paranthaman, A. (2020). Mural Variant of Unicystic Ameloblastoma in a Pediatric Patient: A Rare Case Report. Cureus, 12(12), 11963–11963.

Meenal, V., Nikhil, V., & Madhusudan, A. (2023). Conservative Management of Unicystic Ameloblastoma of Mandible Evolving from Dentigerous Cyst in a Paediatric Patient: A Case Report. J Dent (Shiraz), 24(2), 250–255.

Nascimento, M. A., Cavalcante, W. R. J., Cardoso, S. V., Henriques, J. C. G., & Silva, C. J. (2017). Ameloblastoma unicístico em criança: Relato de caso. ROBRAC, 26(77), 53–56.

Neagu, D., Escuder-de la Torre, O., Vázquez-Mahía, I., Carral-Roura, N., Rubín-Roger, G., Penedo-Vázquez, Á., Luaces-Rey, R., & López-Cedrún, J. L. (2019). Surgical management of ameloblastoma. Review of literature. J Clin Exp Dent, 11(1), 70–75.

Qiao, X., Shi, J., Liu, J., Liu, J., Guo, Y., & Zhong, M. (2021). Recurrence Rates of Intraosseous Ameloblastoma Cases With Conservative or Aggressive Treatment: A Systematic Review and Meta-Analysis. Front Oncol, 11, 647200–647200.

Rikhotso, R. E., & Premviyasa, V. (2019). Conservative Treatment of Ameloblastoma in a Pediatric Patient: A Case Report. J Oral Maxillofac Surg, 77(8), 1643–1649.

Samuel, S., Mistry, F. K., Chopra, S., & Pillai, A. (2014). Unicystic ameloblastoma with mural proliferation: Conservative or surgical approach? BMJ Case Reports.

Santana, T. C. A., Cancio, A. V., Ramos, T. C. F., Hassam, S. F., Cardoso, J. A., & Farias, J. G. (2019). Ameloblastoma unicístico: Relato de caso. RFO UPF, 24(2), 284–291.

Silva, W. R., Lima, C. R. S., Silva, J. G. A., Martins, A. C. M. B., Melo, T. S., & Silva, T. M. V. (2021). Approach and conservative surgical treatment of jaw ameloblastoma: Case report. CES Odontol, 34(2), 188–199.

Silva, J. N., Santos, C. N., Rocha, A. C., Carli, M. L., Hanemann, J. A. C., & Pereira, A. A. C. (2018). Extensive ameloblastoma in young patient: 5-year follow-up with no recurrence using conservative treatment. RGO (Porto Alegre), 66(2), 181–186.

Soares, L. S., Rodrigues, L. D. C. V., Martins, L. N., Silveira, F. D. R., & Figueiredo, M. L. F. (2013). Literature review: particularities of each type of study. Revista de Enfermagem da UFPI. 2(5), 16-17.

Tavares, E. L. N., Nascimento, S. L. C., Martins, V. B., Oliveira, M. V., & Albuquerque, G. C. (2018). Abordagem conservadora de ameloblastoma unicístico com proliferação mural. Rev. cir. traumatol. buco-maxilo-fac, 18(4), 42–47.

Xavier, S. P., Mello-Filho, F. V., Rodrigues, W. C., Sonoda, C. K., & Melo, W. M. (2014). Conservative approach: Using decompression procedure for management of a large unicystic ameloblastoma of the mandible. J Craniofac Surg, 25(3), 1012–1014.

Downloads

Published

22/10/2023

How to Cite

SOUZA, S. V. A. de .; SILVA, L. C. .; FLORES, M. V. da S. .; BRITO, G. C. .; GOMES, R. A. .; BERGAMINI, E. N. .; COLI, A. A. . Conservative treatment of ameloblastoma: A systematic review. Research, Society and Development, [S. l.], v. 12, n. 11, p. e29121143551, 2023. DOI: 10.33448/rsd-v12i11.43551. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/43551. Acesso em: 15 may. 2024.

Issue

Vol. 12 No. 11

Section

Health Sciences

License

Copyright (c) 2023 Sandy Victoria Azevedo de Souza; Letícia Campos Silva; Mariana Viana da Silva Flores; Gabrielle Carvalho Brito; Roberta Amorim Gomes; Eduardo Neves Bergamini; Amanda Achkar Coli

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.