Granular cell tumor: a case report

Authors

DOI:

https://doi.org/10.33448/rsd-v9i8.6474

Keywords:

Mouth neoplasms; Granular cell tumor; Tongue; Case reports.

Abstract

Granular cell tumor (GCT) is an uncommon benign neoplasm of neural origin that affects soft tissues. It has a predilection for females between the 4th and 6th decades of life and its clinically presented as a painless submucosal nodule on tongue. The treatment of choice is the total removal of the lesion, presenting a good prognosis, with rare cases of recurrence. The aim of this study was to report a case of granular cell tumor in a female patient, located on tongue, with about 3 years of evolution. The lesion was completely removed, and the patient remains without signs of recurrence. Thus, the granular cell tumor must be considered as a differential diagnosis of submucosal nodular lesions on tongue.

References

Abrikossoff, A. (1926). Über Myome - ausgehend von der quergestreiften willkürlichen Muskulatur. Virchows Archiv für Pathologische Anatomie und Physiologie und für Klinische Medizin, 260(1), 215–233. Springer-Verlag.

Alotaiby, F. M., Fitzpatrick, S., Upadhyaya, J., Islam, M. N., Cohen, D., & Bhattacharyya, I. (2019). Demographic, Clinical and Histopathological Features of Oral Neural Neoplasms: A Retrospective Study. Head and Neck Pathology, 13(2), 208–214. Humana Press Inc.

Ferreira, J. C. B., Oton-Leite, A. F., Guidi, R., & Mendonça, E. F. (2017). Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report. BMC Research Notes, 10(1), 1–6. BioMed Central Ltd.

van de Loo, S., Thunnissen, E., Postmus, P., & van der Waal, I. (2015). Granular cell tumor of the oral cavity; A case series including a case of metachronous occurrence in the tongue and the lung. Medicina Oral, Patologia Oral y Cirugia Bucal, 20(1), e30–e33. Medicina Oral, Patologia Oral y Cirugia Bucal.

Melo, A. U. C. de, Ribeiro, C. F., de Melo, G. C., Martins-Filho, P. R. S., Ramalho, L. M. P., & Albuquerque Júnior, R. L. C. (2012). Tumores de células granulares na língua: Relato de 2 casos. Revista Portuguesa de Estomatologia, Medicina Dentaria e Cirurgia Maxilofacial, 53(3), 159–164. Elsevier.

Mendoza, I. L. I. de, Ortega, K. L., Trierveiler, M., Alves, M. G. O., Almeida, J. D., Vila, P. G., Urízar, J. M. A., et al. (2020). Oral granular cell tumour: A multicentric study of 56 cases and a systematic review. Oral Diseases, 26(3), 573–589. Blackwell Publishing Ltd.

Serpa, M. S., Costa-Neto, H., Oliveira, P. T. de, Silveira, É. J. D. da, & Medeiros, A. M. C. de. (2016). Granular cell tumor in two oral anatomic sites. European Archives of Oto-Rhino-Laryngology, 273(10), 3439–3441. Springer Verlag.

Tamiolakis, P., Chrysomali, E., Sklavounou-Andrikopoulou, A., & Nikitakis, N. G. (2019). Oral neural tumors: Clinicopathologic analysis of 157 cases and review of the literature. Journal of Clinical and Experimental Dentistry, 11(8), e721–e731. Medicina Oral S.L.

Tobouti, P. L., Pigatti, F. M., Martins-Mussi, M. C., Sedassari, B. T., & de Sousa, S. C. O. M. (2017). Extra-tongue oral granular cell tumor: Histological and immunohistochemical aspect. Medicina Oral Patologia Oral y Cirugia Bucal, 22(1), e31–e35. Medicina Oral, Patologia Oral y Cirugia Bucal.

Published

01/08/2020

How to Cite

MARTINS, H. D. D.; SOUSA, L. H. P. N. de; CARDOSO, C. S.; SOARES, M. S. M.; BONAN, P. R. F. Granular cell tumor: a case report. Research, Society and Development, [S. l.], v. 9, n. 8, p. e885986474, 2020. DOI: 10.33448/rsd-v9i8.6474. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/6474. Acesso em: 25 apr. 2024.

Issue

Section

Health Sciences