Ludwig´s Angina in the diabetic patient: evidence in literature
DOI:
https://doi.org/10.33448/rsd-v9i8.6871Keywords:
Cellulitis; Ludwig’s Angina; Diabetes Mellitus; Diabetes complications.Abstract
Introduction: Ludwig’s Angina (LA) is a head and neck infection potentially fatal, which affects simultaneously submandibular, sublingual, and submental spaces. Diabetes mellitus (DM), due to its immunological and microvascular repercussions, can predispose to LA or modify the patient's response to this infection. Objective: to evaluate the impact of diabetes mellitus on patients with LA. Methods: This study is a literature review in which a search strategy was proposed that used MEDLINE as a database, accessed via PUBMED, limited to the English language and publications between 1954 to 2020. In the research, the following descriptors: “Ludwig's angina” and “diabetes”. Case reports and observational studies approach about Ludwig's angina in diabetic patients were included. Results: 26 articles were found and, after read the abstract, 12 articles were excluded, because there was no relation between LA and DM. Concerning to time of hospital stays, the patients diagnosed with hyperglycemia have a higher hospital stay, due to complications and clinical follow-up. The most common group of microorganisms isolated in diabetic patients was Klebsiella pneumoniae. The antibiotic therapy most commonly used empirically was an association with amoxicillin, clavulanate potassium and metronidazole. Conclusion: It’s possible to observe that Ludwig’s Angina had your clinical evolution modified for diabetes mellitus. The complications involving the association between DM and LA occurs as many diabetic patients without glycemic control, as diabetic patients controlled, to a lesser extent.
References
Botha, A., Jacobs, F., & Postma, C. (2015). Retrospective analysis of etiology and comorbid diseases associated with Ludwig's angina. Ann Maxillofac Surg, 5(2), 168-73. doi: 10.4103/2231-0746.175758
Bross-Soriano, D., Arrieta-Gómez, J. R., Prado-Calleros, H., Schimelmitz-Idi, J., & Jorba-Basave, S. (2004). Management of Ludwig's angina with small neck incisions: 18 years experience. Otolaryngology - Head and Neck Surgery, 130(6), 712-717. doi:10.1016/j.otohns.2003.09.036.
Chen, M.-K., Wen, Y.-S., Chang, C.-C., Lee, H.-S., Huang, M.-T., & Hsiao, H.-C. (2000). Deep neck infections in diabetic patients. American Journal of Otolaryngology, 21(3), 169-173. doi: 10.1053/AJOT.2000.6606
Costain, N., & Marrie, T. J. (2011). Ludwig's angina. The American Journal of Medicine, 124(2), 115-117. doi:10.1016/j.amjmed.2010.08.004
Guzmán-Letelier, M., Crisosto-Jara, C., Diaz-Ricouz, C., Peñarrocha-Diago, M., & Peñarrocha-Oltra, D. (2017). Severe odontogenic infection: An emergency. Case report. J Clin Exp Dent, 9(2), e319-24. doi:10.4317/jced.53308
Huang, T. T., Liu, T. C., Chen, P. R., Tseng, F. Y., Yeh, T. H., & Chen, Y. S. (2004). Deep neck infection: analysis of 185 cases. HEAD & NECK, 26(10), 854-860. doi: 10.1002/hed.20014
Infante-Cossio, P., Fernandez-Hinojosa, E., Mangas-Cruz, M.-A., & Gonzalez-Perez, L.-M. (2010). Ludwig's angina and ketoacidosis as a first manifestation of diabetes mellitus. Med Oral Patol Oral Cir Bucal, 15(4), e624-627. doi:10.4317/medoral.15.e624
Kataria, G., Saxena, A., Bhagat, S., Singh, B., Kaur, M., & Kaur, G. (2015). Deep neck space infections: a study of 76 cases. Iranian Journal of Otorhinolaryngology, 27(81), 293-99. doi: 10.22038/IJORL.2015.4520
Kavarodi, A. M. (2011). Necrotizing fasciitis in association with Ludwig’s angina – a case report. The Saudi Dental Journal, 23(3), 157-160. doi:10.1016/j.sdentj.2011.03.003
Mathew, G. C., Ranganathan, L. K., Gandhi, S., Jacob, M. E., Singh, I., Solanki, M., & Bither, S. (2012). Odontogenic maxillofacial space infections at a tertiary care center in North India: a five-year retrospective study. International Journal of Infectious Diseases, 16(4), e296-e302. doi:10.1016/j.ijid.2011.12.014
Prabhu, S. R., & Nirmalkumar, E. S. (2019). Acute fascial space infections of the Neck: 1034 cases in 17 years follow up. Annals of Maxillofacial Surgery, 9(1), 118-123. doi: 10.4103/ams.ams_251_18
Rao, D. D., Desai, A., Kulkarni, R. D., Gopalkrishnan, K., & Rao, C. B. (2010). Comparison of maxillofacial space infection in diabetic and nondiabetic patients. Oral Medicine, Oral Pathology, Oral Radiology,, & Endodontology, 110(4), e7-e12. doi:10.1016/j.tripleo.2010.04.016
Shah, B. R., & Hux, J. E. (2003). Quantifying the risk of infectious diseases for people with diabetes. Diabetes Care, 26(2), 510-513. doi: 10.2337/diacare.26.2.510
Wadsworth, P. V. (1954). Ludwig's Angina complicated by diabetes mellitus. J Laryngol Otol, 68(4), 247-249. doi: 10.1017/s0022215100049616
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Copyright (c) 2020 Lucas Nunes de Brito Silva, Ingrid Torres de Almeida, Matheus Corrêa da Silva, Lucya Giselle Costa Moreira, Eryck Canabarra Ávila, Elenisa Glaucia Ferreira dos Santos, Emanuel Sávio de Souza Andrade
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