Use of botulinum toxin in the treatment of temporomandibular disorders: integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v9i9.7491

Keywords:

Temporomandibular disorder; Dentistry; Botulinum toxin.

Abstract

Introduction: Temporomandibular disorders (TMDs) have shown an increasing incidence in the population, causing pain and restricting the functions of the stomatognathic system, with that, the botulinum toxin has been gaining space in the dental field and is being used in the treatment of these disorders. Objective: to evaluate the effectiveness of the treatment of TMDs with botulinum toxin, systematizing the scientific evidence on the use of this therapy. Methodology: a search was carried out in the databases: Scientific Electronic Library Online (SCIELO) and US National Library of Medicine (Pubmed), with the descriptors: "Botulinum toxin", "Temporomandibular Disorder" and "Dentistry". The research took place online, and includes original articles in Portuguese and English addressing the proposed theme, published between 2010 and 2020, the exclusion criteria followed by articles in duplicate and that did not include the object of study, as well as theses, dissertations, monographs, books and book chapters. Results: 10 articles were analyzed, in which they reported that the botulinum toxin plays a role in reducing the release of inflammatory mediators that cause pain, becoming effective, without systemic or permanent side effects. Conclusion: Botulinum toxin as a therapeutic method has been shown to be effective in the treatment of TMDs, however, there is a need for further studies in the area.

References

Amantéa, D. V., Novaes, A. P., Campolongo, G. D., & Pessoa de Barros, T. (2003). A utilização da toxina botulínica tipo A na dor e disfunção temporomandibular. JBA, 3(10), 170-3.

Ataran, R., Bahramian, A., Jamali, Z., Pishahang, V., Barzegani, H. S., Sarbakhsh, P., & Yazdani, J. (2017). The role of botulinum toxin a in treatment of temporomandibular joint disorders: a review. Journal of Dentistry, 18(3), 157.

Awan, K. H. (2017). The therapeutic usage of botulinum toxin (Botox) in non-cosmetic head and neck conditions–An evidence based review. Saudi Pharmaceutical Journal, 25(1), 18-24.

Barbosa, E. R., Takada, L. T., Gonçalves, L. R., Costa, R. M. P. D. N., Silveira-Moriyama, L., & Chien, H. F. (2010). Botulinum toxin type A in the treatment of hemifacial spasm: an 11-year experience. Arquivos de neuro-psiquiatria, 68(4), 502-505.

Bogucki, Z. A., & Kownacka, M. (2016). Clinical aspects of the use of botulinum toxin type a in the treatment of dysfunction of the masticatory system. strabismus, 2, 8.

Bratz, P., & Mallet, E. K. V. (2015). Toxina Botulínica Tipo A: abordagens em saúde. Revista Saúde Integrada, 8(15-16).

Colhado, O. C. G., Boeing, M., & Ortega, L. B. (2009). Toxina Botulínica en el Tratamiento del dolor. Revista Brasileira de Anestesiologia, 59(3).

Costa, A. L., Campos, L. S., França Jr, M. C., & D'Abreu, A. (2011). Temporomandibular disorders in patients with craniocervical dystonia. Arquivos de neuro-psiquiatria, 69(6), 896-899.

Dall'Antonia, M., Netto, R. M. D. O., Sanches, M. L., & Guimarães, A. S. (2013). Dor miofascial dos músculos da mastigação e toxina botulínica. Revista Dor, 14(1), 52-57.

De Rossi, S. S., Greenberg, M. S., Liu, F., & Steinkeler, A. (2014). Temporomandibular disorders: evaluation and management. Medical Clinics, 98(6), 1353-1384.

Fassina, M. T., Jóias, R. M., & Jóias, R. P. (2016). Toxina botulínica tipo A nas DTM musculares: há eficácia?. Odonto, 24(48), 1-13.

Huamani, M. A. U., Moreira, L. A., Araújo, N. S. D., Napimoga, M. H., Junqueira, J. L. C., & Miranda, M. E. (2017). Use of botulinum toxin type a in temporomandibular disorder. RGO-Revista Gaúcha de Odontologia, 65(2), 151-155.

Lasalvia, C. G. G., Pereira, L. D. S., Cunha, M. C. D., & Kitadai, S. P. S. (2006). Custos e eficácia da toxina botulínica tipo A no tratamento do blefaroespasmo essencial e espasmo hemifacial. Arquivos Brasileiros de Oftalmologia, 69(5), 701-705.

Mor, N., Tang, C., & Blitzer, A. (2015). Temporomandibular myofacial pain treated with botulinum toxin injection. Toxins, 7(8), 2791-2800.

Teive, H. A., Klüppel, L. E., Munhoz, R. P., Becker, N., Müller, P. R., & Werneck, L. C. (2012). Distonia oromandibular com abertura da boca secundária à doença de Wilson tratada com toxina botulínica tipo A. Arquivos de Neuro-Psiquiatria, 70(6), 407-409.

Published

30/08/2020

How to Cite

SILVA, G. C. da .; LOUREIRO, A. M. S. .; SOUZA, C. T. de L. .; SILVA, N. K. B. .; LIMA, R. F. T. de .; OLIVEIRA, T. B. B. de; COTA, A. L. S. Use of botulinum toxin in the treatment of temporomandibular disorders: integrative review. Research, Society and Development, [S. l.], v. 9, n. 9, p. e589997491, 2020. DOI: 10.33448/rsd-v9i9.7491. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/7491. Acesso em: 23 apr. 2024.

Issue

Section

Review Article