Antimicrobial activity of the essential oil from Bixa orellana L.

Authors

DOI:

https://doi.org/10.33448/rsd-v9i10.8447

Keywords:

Bixa; Essential oil; Toxicity.

Abstract

The application of natural substances with bactericidal action is the target of research aimed at a more sustainable production, implying in various sources of substances for new therapeutic formulations. This study presents the chemical characterization, toxicity and antimicrobial activity of essential oil (EO) of Bixa orellana Labill leaves. EO was extracted by hydrodistillation at 100°C for 3h. Physicochemical parameters were determined and chemical characterization used Gas chromatography coupled with Mass Spectrometry (GC/MS). The toxicity assay was performed through the bioassay with Artemia salina Leach. The methods of Disc Diffusion and Dilution in Broth in front of the bacteria Escherichia coli and Staphylococcus aureus were used to evaluate the antimicrobial activity. LC50 in the toxicity assay was verified in 355 mg L-1 and was classified as nontoxic. The OE presented antimicrobial activity against the microorganisms tested and totaled 320 mg EAT g-1 of total phenolics. The results obtained highlight the importance of pointing out this product as a therapeutic alternative, encouraging its application potential.

Author Biographies

Yuri Nascimento Fróes, Universidade CEUMA

Discente do mestrado em biologia microbiana, laboratório de periodicidade microbiana, Universidade CEUMA.

Ana Patrícia Matos Pereira, Universidade Federal do Maranhão

Mestrando em Saúde e Ambiente - UFMA

Paulo Victor Serra Rosa, Uninersidade Federal do Maranhão

Bacharel em biomedicina pela Faculdade Uninassau.

Laiane Araujo da Silva Souto, Faculdade Uninassau

Bacharel em Nutrição pela Universidade Federal do Maranhão

Mestre em Química - UFMA

Professora Universitária

Mariana Oliveira Arruda, Faculdade Uninassau

Formada em Ciências Biológicas pela UFMA

Mestre em Microbiologia Médica pela UFC

Doutora em Biotecnologia pela UFMA

Luis Felipe Castro Araújo, Universidade Estácio de Sá

Graduado em Nutrição

Andressa Teixeira Costa, Universidade Estácio de Sá

Pós-graduanda em Nutrição Clínica Funcional pela Faculdade Laboro

Danielly Fonseca, Faculdade Uninassau

Bacharel em biomedicina pela Faculdade Uninassau

Dorileia Pereira do Nascimento, Faculdade Uninassau

Bacharel em biomedicina pela Faculdade Uninassau

Joicy Cortez de Sá Sousa, Universidade CEUMA

Docente do mestrado em biologia microbiana, laboratório de periodicidade microbiana, Universidade CEUMA.

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Published

20/10/2020

How to Cite

FRÓES, Y. N. .; PEREIRA, A. P. M. .; ROSA, P. V. S. .; SOUTO, L. A. da S. .; ARRUDA, M. O. .; ARAÚJO, L. F. C. .; COSTA, A. T. .; FONSECA, D. .; NASCIMENTO, D. P. do .; EVERTON, G. O.; MOUCHREK FILHO, V. E. .; SOUSA, J. C. de S. . Antimicrobial activity of the essential oil from Bixa orellana L. Research, Society and Development, [S. l.], v. 9, n. 10, p. e8129108447, 2020. DOI: 10.33448/rsd-v9i10.8447. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/8447. Acesso em: 19 apr. 2024.

Issue

Vol. 9 No. 10

Section

Health Sciences

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Copyright (c) 2020 Yuri Nascimento Fróes; Ana Patrícia Matos Pereira; Paulo Victor Serra Rosa; Laiane Araujo da Silva Souto; Mariana Oliveira Arruda; Luis Felipe Castro Araújo; Andressa Teixeira Costa; Danielly Fonseca; Dorileia Pereira do Nascimento; Gustavo Oliveira Everton; Victor Elias Mouchrek Filho; Joicy Cortez de Sá Sousa

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