The mapping of ovarian cancer mortality trends in Brazil




Ovarian cancer; Mortality; Trend.


Ovarian cancer is the eighth cause of death by cancer in women worldwide. The objective of this study was to analyze trends in the Brazilian ovarian cancer mortality and the relation to age, schooling, and race. Data was collected in the Brazilian Mortality Information System (SIM), from 2006 to 2016. The polynomial regression model was used for the trends analysis, a significant trend was considered when the estimated model obtained a p-value <0.05. Ovarian Cancer caused 34,003 deaths in Brazilian women in this period, the mortality rate (MR) was 0.46 per 100.000 women aged less than 40; 4.2 in women aged between 40 – 59; 12.2 in women aged between 60 – 79 and 19.4 in women 80 years old or more. About Race, 65% were White, others were declared as Black, Asian, Mixed-race, or Indigenous. Only 26% had 8 years or more of schooling. Mortality rates from ovarian cancer seemed to be rising in Brazil, the major increase happened in the South, the Southeast, and the Middle-West Regions. Women aged between 40 to 59 had the most significant increase. Politics are needed to facilitate the Brazilian population's access to health services, consequently minimizing the time to diagnose and start the treatment. Research about mortality rates could help health workers identify gaps in knowledge and consequently decrease the magnitude of the disease.


Chirlaque, M. D., Uhry, Z., Salmerón, D., Sánchez-Zapata, M. I., Zannoni, G. F., Navarro, C., Verne, J. (2017). Trends in net survival from ovarian cancer in six European Latin countries: Results from the SUDCAN population-based study. European Journal of Cancer Prevention, 26(Trends in cancer net survival in six European Latin Countries: the SUDCAN study), S107–S113.

Ervik, M., Lam, F., Ferlay, J., Mery, L., Soerjomataram, I., & Bray, F. (2016). Cancer Today. Retrieved from International Agency for Research on Cancer. Cancer Today. website:

Grossman, D. C., Curry, S. J., Owens, D. K., Barry, M. J., Davidson, K. W., Doubeni, C. A., Tseng, C. W. (2018). Screening for ovarian cancer US preventive services task force recommendation statement. JAMA - Journal of the American Medical Association, 319(6), 588–594.

Henderson, J. T., Webber, E. M., & Sawaya, G. F. (2018). Screening for ovarian cancer updated evidence report and systematic review for the US preventive services task force. JAMA - Journal of the American Medical Association, 319(6), 595–606.

International Agency for Research on Cancer. (2019). Cancer Tomorrow. Retrieved from World Health Organization website:

Keinan-Boker, L., Silverman, B. G., Walsh, P. M., Gavin, A. T., & Hayes, C. (2017). Time trends in the incidence and mortality of ovarian cancer in Ireland, Northern Ireland, and Israel, 1994-2013. International Journal of Gynecological Cancer, 27(8), 1628–1636.

Landmann-Szwarcwald, C., & Macinko, J. (2016). A panorama of health inequalities in Brazil. International Journal for Equity in Health, 15(1), 1–3.

Lowe, K. A., Chia, V. M., Taylor, A., O’Malley, C., Kelsh, M., Mohamed, M., … Goff, B. (2013). An international assessment of ovarian cancer incidence and mortality. Gynecologic Oncology, 130(1), 107–114.

Lowry, K. P., & Lee, S. I. (2017). Imaging and Screening of Ovarian Cancer. Radiologic Clinics of North America, 55(6), 1251–1259.

Malvezzi, M., Carioli, G., Rodriguez, T., Negri, E., & La Vecchia, C. (2016). Global trends and predictions in ovarian cancer mortality. Annals of Oncology, 27(11), 2017–2025.

Murthy, N. S., Shalini, S., Suman, G., Pruthvish, S., & Mathew, A. (2009). Changing trends in incidence of ovarian cancer - the Indian scenario. Asian Pacific Journal of Cancer Prevention : APJCP, 10(6), 1025–1030. Retrieved from

Ojamaa, K., Veerus, P., Baburin, A., Everaus, H., & Innos, K. (2017). Time Trends in Ovarian Cancer Survival in Estonia by Age and Stage. International Journal of Gynecological Cancer, 27(1), 44–49.

Park, H. K., Ruterbusch, J. J., & Cote, M. L. (2017). Recent trends in ovarian cancer incidence and relative survival in the United States by race/ethnicity and histologic subtypes. Cancer Epidemiology Biomarkers and Prevention, 26(10), 1511–1518.

Rocha-brischiliari, S. C., Rosseto, R., Oliveira, D., & Pelloso, S. M. (2017). The Rise in Mortality from Breast Cancer in Young Women : Trend Analysis in Brazil. 1–13.

SEYFERTH, G. (2013). Colonização, Imigração E a Questão Racial No Brasil. Revista USP, 0(53), 117.

Sharifian, A., Pourhoseingholi, M. A., Norouzinia, M., & Vahedi, M. (2014). Ovarian cancer in Iranian women, a trend analysis of mortality and incidence. Asian Pacific Journal of Cancer Prevention, 15(24), 10787–10790.

Sopik, V., Iqbal, J., Rosen, B., & Narod, S. A. (2015). Why have ovarian cancer mortality rates declined? Part I. Incidence. Gynecologic Oncology, 138(3), 741–749.

Webb, P. M., Green, A. C., & Jordan, S. J. (2017). Trends in hormone use and ovarian cancer incidence in US white and Australian women: implications for the future. Cancer Causes and Control, 28(5), 365–370.

Wright, A. A., Bohlke, K., Armstrong, D. K., Bookman, M. A., Cliby, W. A., Coleman, R. L., Edelson, M. I. (2016). Neoadjuvant chemotherapy for newly diagnosed, advanced ovarian cancer: Society of Gynecologic Oncology and American Society of Clinical Oncology Clinical Practice Guideline. Gynecologic Oncology, 143(1), 3–15.




How to Cite

SANTOS, L. dos; ROSZKOWSKI, I.; DUTRA, A. de C.; TOMAS, A. C. V. .; PELLOSO, F. C.; ANDRADE, L. de; PEDROSO, R. B. .; CARVALHO, M. D. de B. .; MELO, W. A. de; PELLOSO, S. M. . The mapping of ovarian cancer mortality trends in Brazil . Research, Society and Development, [S. l.], v. 9, n. 10, p. e5749108828, 2020. DOI: 10.33448/rsd-v9i10.8828. Disponível em: Acesso em: 18 aug. 2022.



Health Sciences