The journal Research, Society and Development (abbreviated as Res. Soc. Dev.) is a multidisciplinary scientific publication focused on promoting the dissemination of knowledge, using scientific methodologies for social, scientific and technological development through the publication of manuscripts, results and conclusions of research, in the various areas of knowledge. It is a monthly online journal. Submissions are evaluated by peers (Double Blind Review) with experience in the area of ​​the manuscript. Ad hoc revisors 2025 We thank all of the more than 340 “ad hoc” reviewers who contributed to this Journal in their evaluations (double-blind peer review). Reviewers 2025
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Association of interocclusion device and viscosupplementation with hyaluronic acid for the treatment of osteoarthritis in the temporomandibular joint: Case report
Objective: To report a case on the association of an interocclusal device and viscosupplementation with hyaluronic acid in the treatment of osteoarthritis of the temporomandibular joint. Materials and Methods: Descriptive, retrospective, qualitative study, using direct observation technique (Pereira et al. 2018), in Portuguese and English, using textbooks in the area of ​​TMD and Orofacial Pain and the Pubmed, Google Scholar, LILACS, MEDLINE, and SCIELO databases. Case report: A 23-year-old female patient, with leucoderma, presented with the chief complaint of "a crepitus sound when I open my mouth," bilaterally, but without pain. Based on clinical findings and cone-beam computed tomography, the diagnosis was osteoarthritis. The recommended treatment was viscosupplementation with Ostenil hyaluronic acid (1.0% sodium hyaluronate) combined with the use of an interocclusal device. Results: The combination reduced the degenerative impacts of osteoarthritis and provided sustainable symptomatic relief for the patient, with no crepitus sound observed in the right temporomandibular joint (TMJ) after viscosupplementation. On the left side, the crepitus sound changed to a clicking sound, shifting from osteoarthritis to disc displacement with reduction (DDCR). Conclusion: Hyaluronic acid (HA) is effective in regulating intra-articular inflammatory biochemistry and improving lubrication of articular structures. Interocclusal devices help reduce the impact of overload on articular structures, promoting the repair of articular tissues. Finally, in this case report, there was a significant improvement in clinically observed signs and symptoms after the concomitant use of the detailed therapeutic techniques.
Copyright (c) 2026 Yasmim Bom Bueno de Souza, Letícia Braga Peixoto, Mateus Moraes Costa Guimarães, Katharina Jucá de Moraes Fernandes, João Francisco Tenório Neto https://creativecommons.org/licenses/by/4.0
Microencapsulation of Lactobacillus acidophilus in coconut oil emulsion and its viability during storage at room temperature
The development of probiotic foods faces challenges related to maintaining the viability of microorganisms during shelf life at room temperature. Most probiotic products currently available require refrigeration to ensure the survival of beneficial bacteria, which limits their application in different food matrices. In this context, microencapsulation strategies have been investigated to protect microorganisms against adverse environmental conditions. The present study aimed to develop an encapsulation system for Lactobacillus acidophilus using coconut oil as an encapsulating material and to evaluate probiotic viability during storage at room temperature. Lyophilized cultures were dispersed in melted coconut oil, cooled to form solid lipid particles, and subsequently emulsified in an aqueous medium. Samples were stored at 19 °C for 12 weeks, during which microbiological analyses were performed, along with pH and titratable acidity measurements. The encapsulated probiotic showed a reduction of only 1.6 logarithmic cycles after 12 weeks, maintaining counts above 10⁷ CFU g⁻¹, whereas the non-encapsulated probiotic showed counts lower than 10¹ CFU g⁻¹ after 5 weeks. The results indicate that coconut oil has potential as an encapsulating material for probiotics in foods stored at room temperature.
Copyright (c) 2026 Carolina Vitor Miguel, Sandra Regina Alves Confort, Diana Clara Nunes de Lima, Miguel Meirelles de Oliveira https://creativecommons.org/licenses/by/4.0
Immunogenetic aspects of multiple sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system, characterized by demyelination and progressive neurodegeneration, in which immunogenetic factors play a central role in susceptibility and clinical progression. The HLA-DRB1*1501 allele stands out, as it is associated with aberrant activation of the adaptive immune response. The present study aims to critically review the main immunogenetic aspects of multiple sclerosis, with emphasis on the role of the HLA-DRB1*1501 allele, on immune pathways mediated by Th1 and Th17 cells, and on the interaction between genetic and environmental factors. Method: This is a systematized literature review conducted according to the recommendations of the PRISMA 2020 protocol. The search was performed in the PubMed/MEDLINE, Scopus, Web of Science, SciELO, and LILACS databases, covering studies published between 2010 and 2025. Original articles, systematic reviews, and meta-analyses addressing immunogenetics and immune response in MS were included. Results: The analyzed studies demonstrate a potential association between the HLA-DRB1*1501 allele and an increased risk of MS, in addition to highlighting the central role of Th1 and Th17 cells and pro-inflammatory cytokines in the breakdown of immune tolerance, neuroglial inflammation, and disease progression. Environmental factors and other associations may modulate genetic expression and immune response. Conclusion: MS results from a complex interaction between immunogenetic predisposition and environmental factors, with HLA-DRB1*1501 being one of the main possible risk determinants. Understanding these mechanisms is essential for the development of personalized diagnostic and therapeutic strategies.
Copyright (c) 2026 Ana Karoliny Silva Torrejais, Rafaela Queiroz Bôsco, Gabriel Ribeiro Castro, Ana Maisa Passos-Silva https://creativecommons.org/licenses/by/4.0
Diagnosis of pathological manifestations in school buildings using ultrasonic testing
Assessing the integrity of concrete structures in public buildings is fundamental to ensuring user safety and the durability of constructions, especially in schools, which have high occupancy rates and often face limitations related to preventive maintenance. Non-destructive testing stands out as an efficient tool for structural diagnosis, as it allows for the evaluation of the internal conditions of concrete without causing damage to structural elements. The ultrasonic pulse velocity test makes it possible to estimate the homogeneity of the material and identify possible internal discontinuities. Thus, this study aimed to evaluate the quality of concrete and identify pathological manifestations in structural elements of two public schools located in the municipality of Açailândia–MA: the Professor José Cesário Teaching Center and the Egídio Quintal Filho Municipal School. The methodology consisted of visual inspection combined with the application of ultrasonic tests on selected pillars of the buildings, using direct and indirect transmission methods, with multiple measurements per element, according to the recommendations of ABNT NBR 8802:2019. The results allowed for the classification of the concrete quality of the analyzed structures, indicating variations in wave propagation velocities associated with material heterogeneity and the presence of possible internal discontinuities. A correlation was also observed between regions with lower ultrasonic velocities and the occurrence of visible pathological manifestations, such as cracks and signs of moisture. It is concluded that ultrasonic testing is a suitable tool for the preliminary assessment of the structural integrity of school buildings, contributing to technical diagnosis and the planning of preventive maintenance actions.
Copyright (c) 2026 Francisco Matheus da Silva Barros, Walneis Thiago Silva Santos, Lucas da Silva Soares https://creativecommons.org/licenses/by/4.0
Effects of feeding rate and feeding frequency on water quality and growth performance of juvenile tambaqui in a biofloc system
Biofloc technology (BFT) stands out as a promising strategy for intensive aquaculture, where feeding rate and frequency are key management factors. This study aimed to evaluate the short-term effects of different feeding rates and feeding frequencies on water quality and growth performance of juvenile tambaqui (Colossoma macropomum) during the initial rearing phase in a biofloc system over 14 days. One hundred and twenty fish (2.42 ± 0.20 g) were used, distributed in a completely randomized design, in a 2×4 factorial scheme, with three replicates. The physicochemical parameters of the water remained generally stable; however, the feeding rate influenced dissolved oxygen and nitrite, with less favorable conditions at a rate of 10%. Feeding frequency affected total ammonia nitrogen, indicating interference in nitrogen dynamics. No significant differences were observed in growth parameters between treatments. However, the feeding rate impacted feed intake and feed conversion, with the 5% rate being the most efficient. Feeding frequency did not influence growth performance, indicating physiological and feeding plasticity of the species. A feeding rate of 5% is more suitable, as it reduces environmental impacts without compromising growth.
Copyright (c) 2026 Ríleury Guilherme dos Santos Gomes, Sharliane dos Santos Gomes, Carolyne da Costa Sadala, Francisco Vitor Batista do Nascimento, Jaizinho Oliveira Alves, Marcella Costa Radael, Gabriel Francisco de Oliveira Alves https://creativecommons.org/licenses/by/4.0
Brazil in growth: Regional patterns of live births and prenatal care in 2024
Objective: to describe the sociodemographic, obstetric, and neonatal profiles of live births in Brazil in 2024, by macro-region. Methods: This is a descriptive ecological study based on secondary data from the Live Birth Information System (SINASC/DATASUS). Sociodemographic, obstetric, and neonatal variables were analyzed using absolute and relative frequencies. Regional comparisons were performed using the chi-square test (χ²), adopting a significance level of p<0.05. Results: a total of 2,384,438 births were analyzed. A higher proportion of adolescent mothers was observed in the North (22.3%) and Northeast (19.7%), while higher maternal education levels were found in the Southeast (78.4%) and South (74.9%). Coverage of ≥7 prenatal visits reached 85.5% in the South and 64.9% in the North. The cesarean section rate was high (60.6%), with higher proportions in the Midwest (66.6%) and South (63.1%). Prematurity and low birth weight were more frequent in the North and Northeast. Significant regional heterogeneity was observed (p<0.001). Conclusion: Despite broad healthcare coverage, persistent regional inequalities in prenatal care and neonatal outcomes highlight the need to strengthen public policies focused on equity and quality in maternal and child healthcare.
Copyright (c) 2026 Márcio Cristiano de Melo, Naila Albertina de Oliveira, Jucilene Casati Lodi, Lia Maristela da Silva Jacob, Herla Maria Furtado Jorge, Ana Carine Arruda Rolim https://creativecommons.org/licenses/by/4.0
Effects of resistance exercises on bone mineral density in older adults with osteopenia or osteoporosis
Aging is associated with physiological changes that compromise bone health, especially the reduction of Bone Mineral Density (BMD), a factor directly related to the development of osteoporosis and osteopenia. In this context, resistance exercise has been widely used as a non-pharmacological strategy for the prevention and treatment of these conditions. This study aimed to analyze the influence of resistance exercise on bone mineral density in older adults with osteoporosis or osteopenia, considering its benefits in preventing bone loss and promoting functional health.This is a descriptive literature review with a qualitative approach, conducted through searches in the PubMed, SciELO, and PEDro databases, covering the period from 2014 to 2025. Eight full-text studies in Portuguese and English were included, prioritizing randomized clinical trials, systematic reviews, and meta-analyses.The results showed that resistance exercise promotes positive effects on bone mineral density, especially in the lumbar spine, with varying magnitudes across different bone regions. It was also observed that parameters such as intensity, frequency, and duration of training directly influence bone response, while gains in muscle strength and functionality were more consistent and occurred earlier, contributing to the reduction of fall and fracture risk.It is concluded that resistance exercise, when properly prescribed, is an effective strategy for preventing bone loss and promoting functional health in older adults.
Copyright (c) 2026 João Vitor Duar Calazani Teixeiras, Ramon Repolês Soares https://creativecommons.org/licenses/by/4.0
Economic viability of productive backyard gardens in agrarian reform settlements in southeastern Pará
This study aims to investigate how the integration of sustainable practices can contribute to strengthening the economic structure of rural settlements, guaranteeing their productive autonomy and expanding their contribution to sustainable development. It is based on the assumption that the viability of these systems depends not only on monetary income, but also on indirect benefits such as self-sufficiency and reduced expenses. Methodologically, a descriptive approach was adopted, based on observable gross revenue per item, considering only data with quantity and price, due to the absence of systematic records of costs and profits. The results show that the backyards present high productive diversity, including fruit trees, processing, and small-scale livestock farming. However, the generation of monetary income tends to be concentrated in a few higher value-added items, such as pulps and derivatives, with acerola pulp standing out in the Nova Vitória Settlement Project. In the backyards of the Deus te Ama Settlement Project, a larger productive scale and strong participation of products such as flour, pineapple, and pulps are observed. At the Nova Canaã Camp, the system is in the implementation phase, without observable revenue generation. The analysis demonstrates that productive diversity ensures flexibility, food security, and resilience, while processing and insertion into local markets boost income. Possible trade-offs are also identified, since commercial intensification can reduce diversity and compromise the social functions of the backyard. It is concluded that productive backyards are strategic systems, whose analysis should integrate economic, social, and environmental dimensions, valuing both monetary income and indirect benefits.
Copyright (c) 2026 Márcia Aparecida Miranda de Azevedo, Manoel Tavares de Paula https://creativecommons.org/licenses/by/4.0
Use of Artificial Intelligence and self-medication with psychotropic drugs: Evidence from a cross-sectional study with Medical students
The increasing use of Artificial Intelligence (AI) technologies in healthcare has broadened access to information and influenced self-care behaviors, including self-medication. In the context of mental health, this phenomenon is especially relevant due to the risks associated with the inappropriate use of psychotropic drugs. This study aimed to analyze the use of AI in self-medication among medical students, discussing implications for medical training and digital health literacy. This is a descriptive, qualitative, case study study with 35 students from a private institution located in the state of Rio de Janeiro. Data was collected through a semi-structured questionnaire, and the analysis followed Bardin's technique. The results showed high use of AI and a prevalence of self-medication. It is concluded that AI acts as an informational source, influencing behaviors and highlighting the need for its critical use in medical training.
Copyright (c) 2026 Vitoria do Carmo Frejoli, Suellen Gomes Barbosa Assad https://creativecommons.org/licenses/by/4.0
Variabilidad hidroquímica y su relación con el caudal regulado en un estuario tropical: Bahía de Iguape (BA, Brasil)
The regulation of river discharge by dams represents an important anthropogenic factor with the potential to alter hydrochemical patterns in estuarine systems. The objective of this study was to analyze the spatiotemporal variability of water quality parameters and its relationship with regulated discharge in the Iguape Bay estuary (BA, Brazil), based on monthly sampling conducted at nine sites between September 2023 and October 2024. Salinity, dissolved oxygen, pH, electrical conductivity, and total dissolved solids were measured, and descriptive and multivariate statistical analyses were applied, including Principal Component Analysis (PCA). The results indicated consistent associations between discharge conditions and hydrochemical variability. Periods of lower discharge generally showed higher salinity and ionic concentration values, suggesting greater marine influence, while periods of higher discharge were associated with dilution of salts and improved oxygen conditions. PCA explained 68.4% of the total variability and revealed seasonal patterns consistent with the regional hydrological regime. The results should be interpreted considering limitations related to sampling frequency and the lack of detailed hydrodynamic characterization. Thus, the study does not establish causal relationships, but identifies patterns and associations that contribute to the understanding of hydrochemical variability in tropical estuaries under regulated discharge.
Copyright (c) 2026 Marta Maria Barros de Jesus Santos, Carla Fernandes Macedo, Mara Rojane Barros de Matos https://creativecommons.org/licenses/by/4.0
The influence of physical activity on reducing medication use in elderly people with chronic diseases: A study conducted in a neighborhood in the eastern zone of Manaus, Amazonas State, Brazil
This study aimed to analyze the influence of regular physical activity on reducing medication use among older adults with chronic diseases living in a neighborhood in the East Zone of Manaus, Amazonas, Brazil. It is an integrative literature review with a quantitative approach, based on searches conducted in the PubMed/MEDLINE, SciELO, and Virtual Health Library databases, using Portuguese and English descriptors drawn from DeCS and MeSH and combined with Boolean operators. Full-text articles published in Portuguese, English, or Spanish addressing the relationship between physical activity, chronic diseases, and medication use in older adults were included, with priority given to randomized controlled trials, without excluding other relevant study designs. The findings indicated that regular physical activity is associated with improvements in clinical parameters such as blood pressure and glycemic control, increased functional capacity, and better quality of life, in addition to showing potential for reducing medication dosage or the number of medications used, especially among older adults with hypertension and diabetes mellitus. It was concluded that physical activity is an important, accessible, and low-cost non-pharmacological strategy that may contribute to chronic disease control, reduction of polypharmacy, and health promotion in the older population.
Copyright (c) 2026 Victor Emanuel da Silva Barbosa, Ronie Soares de Sousa, Paula Adriana dos Santos de Fontes https://creativecommons.org/licenses/by/4.0
Autogenous bone grafts based on dentin matrix: Efficacy and clinical applications
Bone regeneration is one of the main challenges in contemporary oral rehabilitation, with autogenous grafting being the gold standard, despite limitations such as donor site morbidity. In this context, autogenous dentin matrix (ADM) has emerged as a promising biomaterial due to its chemical and structural similarity to bone tissue. This study aimed to investigate, through an integrative literature review, the possibilities and limitations of using autogenous bone grafts based on the dentin matrix in dentistry. The methodology involved systematic searches in the PubMed, Cochrane, and BVS databases (2020-2025), resulting in the analysis of 17 selected articles. The results show that dentin has a chemical and structural composition similar to bone tissue, being composed of hydroxyapatite, type I collagen, and growth factors such as bone morphogenetic proteins (BMPs). These characteristics give the material osteoconductive and osteoinductive properties. The clinical preparation of the material requires cleaning, grinding into particles, and partial demineralization, a process that can be automated by systems such as the Tooth Transformer®. Clinically, MDA demonstrates efficacy in alveolar preservation, sinus lifts, and guided bone regeneration, exhibiting volumetric stability and bone neoformation quality comparable to or superior to xenogeneic biomaterials. It is concluded that the dentin matrix is ​​a viable, safe, and bioactive alternative that minimizes surgical morbidity by eliminating the need for additional donor sites. Limitations lie in its restricted availability to patients with teeth indicated for extraction and the current lack of universal standardization for processing and demineralization protocols.
Copyright (c) 2026 Wendel Carlos da Fonseca Profeta, Gabriel Luiz e Silva de Souza, Bruna Mota Gonçalves Pinto, Renata Maria Colodette https://creativecommons.org/licenses/by/4.0
Substrate-driven structuring of an invasive bivalve in a groundwater-influenced rocky mangrove system
Mangrove ecosystems are highly productive coastal environments increasingly threatened by biological invasions, which can alter community structure and ecosystem functioning. The invasive bivalve Isognomon bicolor (C. B. Adams, 1845), native to the Caribbean, has expanded along the Brazilian coast; however, its ecological dynamics in non-conventional mangrove systems remain poorly understood. This study evaluates the population structure of I. bicolor in the Mangue de Pedra, a unique groundwater-influenced rocky mangrove located in Armação dos Búzios (Rio de Janeiro, Brazil). A quantitative sampling design was applied using 30 quadrats (0.09 m² each) distributed across three microhabitats: roots/muddy substrate, rocky talus, and consolidated rocky shore. A total of 1,351 individuals were recorded, with 100% occurrence across all sampled quadrats, indicating widespread distribution at the local scale. However, abundance varied markedly among habitats, with higher densities in consolidated substrates (1120.0 ind m⁻²), intermediate values in rocky talus (312.2 ind m⁻²), and lower densities in muddy root-associated environments (68.9 ind m⁻²). This pattern demonstrates a clear decoupling between occurrence and abundance, indicating that while dispersal facilitates broad colonization, local environmental filtering, particularly substrate stability, plays a key role in regulating population density. The structural heterogeneity and hydrological connectivity of the Mangue de Pedra suggest that this system may function both as a recipient environment and as a potential source of propagules.
Julio Cesar Quintanilha Peres dos Santos
Ana Polycarpa de Almeida Marinho Carvalho
Copyright (c) 2026 Luciano Carvalho Rapagnã, Jaqueline Pereira de Azeredo Rapagnã, Bianca Cardoso Duarte de Souza, Julio Cesar Quintanilha Peres dos Santos, Gabriela da Silva Marques, Ana Polycarpa de Almeida Marinho Carvalho https://creativecommons.org/licenses/by/4.0
Unpacking school culture as a multidimensional construct: Validation of the School Culture Scale (SCS) in educational leadership contexts
Understanding and measuring school culture remains a critical yet methodologically challenging task in educational research, given its multidimensional and context-dependent nature. This study contributes to this field by providing a comprehensive psychometric validation of the School Culture Scale (SCS) within the Greek educational context, while also addressing broader issues related to the cross-cultural applicability of measurement instruments. Drawing on data from school principals, the study employs both Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) to examine the scale’s internal structure, alongside reliability and correlational analyses. The findings demonstrate strong internal consistency across all dimensions and provide empirical support for the original four-factor model, confirming the theoretical robustness of the instrument. At the same time, minor διαφοροποιήσεις in item loadings highlight the sensitivity of school culture constructs to contextual and institutional conditions. The positive intercorrelations among factors further reinforce the conceptualization of school culture as a dynamic and interconnected system shaping relationships, expectations, and learning processes within schools. Beyond its national scope, the study offers important contributions to the international literature by supporting the cross-cultural validity of the SCS while emphasizing the necessity of context-sensitive validation. The results position the SCS as a robust and adaptable tool for comparative research, as well as for informing leadership practices and school improvement efforts. Overall, the study advances both the methodological rigor and the theoretical understanding of school culture as a key driver of educational quality and organizational change.
Copyright (c) 2026 Smaragdi Tsirantonaki, Anastasia Vlachou https://creativecommons.org/licenses/by/4.0
Body Dysmorphic Disorder in patients seeking facial harmonization
The increasing demand for orofacial harmonization procedures, driven by aesthetic standards disseminated through social media, has highlighted its association with Body Dysmorphic Disorder (BDD), a condition characterized by excessive concern with perceived physical flaws and persistent dissatisfaction. This study aimed to analyze the relationship between BDD and the search for facial aesthetic procedures, as well as the responsibility of dental professionals in such cases. This is a qualitative and descriptive literature review conducted in the SciELO, PubMed, Virtual Health Library, and Google Scholar databases, including publications from 2013 to 2026. After applying eligibility criteria, 17 articles were included in the final sample. The findings indicate that the prevalence of BDD is significantly higher among patients seeking facial aesthetic procedures, reaching up to twenty times that of the general population. These individuals present distorted self-image and repeatedly undergo interventions without achieving lasting satisfaction, since the disorder has a psychological origin. It is concluded that facial harmonization may represent an iatrogenic risk in patients with BDD, making early identification, prior psychological assessment, and ethical conduct by dental professionals essential, prioritizing mental health and comprehensive patient care.
Copyright (c) 2026 Beatriz Mendonça Alves Costa, Monica Parentoni Passos https://creativecommons.org/licenses/by/4.0
Investigative use of three-dimensional models in Embryology teaching: A pedagogical approach based on active learning
The teaching of Embryology presents challenges related to the understanding of dynamic and three-dimensional processes. The use of three-dimensional models has been widely employed as a teaching resource to facilitate visualization. However, it remains unclear whether the potential of these representations is limited to observation or whether it can be expanded when they are used as tools for investigating developmental events. This study aims to describe and analyze a pedagogical proposal based on the investigative use of three-dimensional models representing developmental processes in an Embryology class, integrated into lecture-based sessions, with the purpose of promoting greater attention, participation, and understanding of the sequence of developmental events. This is a qualitative experience report conducted with undergraduate students in the health field. The activity involved the use of unlabeled models, following theoretical instruction, challenging students to identify the represented processes, place them within the temporal sequence, and reconstruct the stages of development. Students were organized into groups and were allowed to use different support resources during the investigation, while the instructor acted as a mediator throughout the activity. The results indicated high levels of engagement, active participation, and the mobilization of learning strategies, evidenced by peer interaction, autonomous information-seeking, and the collective reconstruction of developmental processes. It is concluded that the pedagogical potential of three-dimensional models does not lie solely in their tridimensionality, but in how they are mobilized within the teaching process, enhancing their role as investigative tools and fostering more active learning in Embryology education.
Copyright (c) 2026 Simone Marcuzzo, Vitória Oliveira Vargas, Lenir Orlandi Pereira https://creativecommons.org/licenses/by/4.0
Creation of an integrated risk classification system for large events within the Military Police of Alagoas as a tool to support civil disturbance control
This study aims to develop an integrated risk classification system for large events within the Military Police of Alagoas as a tool to support civil disturbance control. The research is applied in nature, with a qualitative approach, based on bibliographic review, document analysis, and operational experience. The proposed model is structured around key variables — such as event type, public profile, history of occurrences, alcohol consumption, location characteristics, and social context — organized into a scoring system for risk classification. The results indicate that the use of objective criteria reduces subjectivity in decision-making, improves operational planning, optimizes resource allocation, and strengthens preventive actions. Furthermore, the system contributes to aligning police actions with the proportional use of force and the preservation of public order. It is concluded that the adoption of structured risk management tools represents a significant advancement in the modernization of police operational practices.
Copyright (c) 2026 Thiago Barros Oliveira https://creativecommons.org/licenses/by/4.0
Agronomic evaluation of poultry litter in nutrient management in Wheat (Triticum aestivum L.) cultivation
Wheat (Triticum aestivum) is one of the most economically important cereal crops worldwide, being used for both human consumption and animal feed. Owing to the high production costs, its cultivation has become less attractive. The objective of this study was to evaluate the use of broiler poultry litter as a substitute for nitrogen fertilization on wheat yield in a Red Latosol in the state of Paraná, Brazil. The experiment was conducted in Bom Sucesso, Paraná State, Brazil, under the following treatments: T1 – control (no fertilisation); T2 – 2 t ha⁻¹ of poultry litter; T3 – 1 t ha⁻¹ of poultry litter; T4 – 3 t ha⁻¹ of poultry litter; and T5 – 250 kg ha⁻¹ of the 10-15-15 mineral fertiliser. The poultry litter used in this experiment was obtained from the same farm where the trial was established, originating from a broiler production system. Each treatment was applied to a 5 × 5 m plot, with four replicates per treatment arranged in a completely randomised design. Morphological and reproductive variables of wheat were assessed through analysis of variance. Treatment 4 (3 t ha⁻¹ of poultry litter) proved to be a viable alternative to mineral fertilisation (Treatment 5: 250 kg ha⁻¹ of 10-15-15), as it achieved comparable plant morphological characteristics while providing greater economic return to the farmer. It can therefore be concluded that organic fertilisation using poultry litter is an effective strategy for reducing fertiliser-related production costs in wheat cultivation.
Copyright (c) 2026 Murilo Incerte Dias, Stephanie Abisag Sáez Meyer Piazza, Pedro Luan Ferreira da Silva, Amanda Eustachio Pereira, Jean Evens Alcinat, Edneia Aparecida de Souza Paccola, Anny Rosi Mannigel https://creativecommons.org/licenses/by/4.0
Duchenne muscular dystrophy in Brazil: Advances, gaps, and challenges in diagnosis and treatment
Duchenne Muscular Dystrophy (DMD) is a rare, progressive genetic disorder associated with high morbidity and mortality, whose clinical management has evolved with advances in molecular diagnostics and disease-modifying therapies. However, in Brazil, significant gaps remain in scientific production, diagnostic access, and healthcare organization. This study aimed to analyze national scientific production on DMD, identifying methodological patterns, geographic distribution, diagnostic and therapeutic approaches, and knowledge gaps. This scoping review followed PRISMA-ScR guidelines. Searches were conducted in PubMed, SciELO, LILACS, and gray literature, considering publications from the last ten years. Original studies including Brazilian population data were selected. Study selection followed identification, screening, eligibility, and inclusion phases, and data were extracted and descriptively synthesized. Sixteen studies were included, with predominance of observational designs and case reports. Sample sizes ranged from 1 to 166 participants, with wide age variation. Cases were concentrated in the Southeast region (n = 154), followed by the Northeast (n = 94), South (n = 28), and North (n = 1), in addition to multicenter studies (n = 166). Studies addressed clinical, genetic, therapeutic, and economic aspects, highlighting the use of MLPA and NGS. Scientific production on DMD in Brazil is expanding but remains characterized by methodological heterogeneity and regional asymmetries, reinforcing the need for multicenter studies and early diagnosis strategies.
Copyright (c) 2026 João Vitor Santos Nogueira, Gabriel da Silva Viana, Guilherme dos Santos Portugal Gomes, Luciano Carvalho Rapagnã https://creativecommons.org/licenses/by/4.0
Performance evaluation within the context of human resource management
Performance evaluation is a constant of each person's performance in the position and their potential for future development. Thus, the general objective of this study was to analyze how performance evaluation is conducted within the scope of human resources management. To conceptualize this general objective, the following specific objectives were defined: present the concepts of performance evaluation; highlight the objectives of performance evaluation, as well as its benefits; identify the models of performance evaluation used and the focus on assessing potential. Methodologically, it is a bibliographic study of a qualitative nature. The literature consulted indicates that once the action plan specifically planned for the worker is developed, the manager should present the action plan to the evaluated employee and later meet again with the Human Resources professional in order to complete the performance evaluation process, ultimately leaving the responsibility to the manager through the monitoring of the evaluated individual regarding the effective compliance with the action plan directed at the evaluated. The study showed that criticisms are raised about the method used for the implementation of performance evaluation, as it incurs high costs in the processing of the procedure due to consuming a lot of time from the manager and the Human Resources professional for each evaluated individual. Moreover, the evaluated individual has minimal participation in the process and is subjectively obliged to meticulously fulfill a plan that was developed without their participation.
Felismina Claudete Madalena Afonso Catrongo
Copyright (c) 2026 Felismina Claudete Madalena Afonso Catrongo, Joaquina Madalena https://creativecommons.org/licenses/by/4.0
Physiotherapeutic rehabilitation of patients with traumatic orthopedic diseases of the lower limbs in the postoperative period: A literature review
This study addresses physiotherapeutic rehabilitation in the postoperative period of traumatic orthopedic diseases affecting the lower limbs, highlighting its importance in functional recovery and improvement of patients’ quality of life. The objective is to investigate the relevance of physiotherapy in this process, analyzing the main resources, techniques, and outcomes related to motor recovery, prevention of complications, and promotion of patient autonomy.This is a descriptive literature review with a qualitative approach, developed through the analysis of scientific publications from 2021 to 2025. The bibliographic search was conducted in the PubMed database, using standardized descriptors in English based on DeCS/MeSH vocabularies, combined through Boolean operators.The results demonstrate that physiotherapy plays an essential role in postoperative rehabilitation, significantly contributing to improvements in mobility, muscle strength, and functional independence. The main interventions include therapeutic exercises, kinesiotherapy, gait training, aquatic physiotherapy, and specific techniques such as blood flow restriction. Additionally, early physiotherapeutic intervention proved to be crucial in reducing complications, shortening hospital stay, and improving clinical outcomes.It is concluded that physiotherapeutic care is fundamental in the recovery process of patients with traumatic orthopedic impairments of the lower limbs and should be conducted in an individualized manner, based on scientific evidence.
Copyright (c) 2026 Ana Carolina Milagres, Andrês Chiapeta https://creativecommons.org/licenses/by/4.0
Efficacy of photodynamic therapy as an adjunct to conventional endodontic treatment in the disinfection and microbial control of root canals
Endodontic treatment is used to prevent and treat diseases of pulpal and periapical origin. Its success is also directly linked to the maximum elimination of microbial infection in the root canal system (RCS), whose anatomical complexity imposes limitations on conventional chemomechanical preparation (CMP), allowing the persistence of pathogens, which leads to treatment failures. Therefore, this study aimed to evaluate the effectiveness of Antimicrobial Photodynamic Therapy (aPDT) as an auxiliary method in the disinfection and microbial control protocol of root canals. Data collection was carried out in the PubMed, SciELO, and LILACS databases (accessed through the Virtual Health Library), using the descriptors "Photodynamic Therapy", "Root Canal", "Disinfection", and "Endodontics". The inclusion criteria adopted were: articles published in the last five years, in English, Portuguese, or Spanish, full text and free of charge, and within the investigated theme. According to the articles analyzed, it was found that PDT acts by activating a photosensitizer by light in the presence of oxygen, generating Reactive Oxygen Species (ROS) that cause lethal oxidative damage to microorganisms. The results show that the application of PDT, in addition to PQM, significantly enhances disinfection, being highly effective in eliminating bacteria in biofilms and resistant strains, even in hard-to-reach areas. It is concluded that Antimicrobial Photodynamic Therapy is a safe, minimally invasive tool, whose incorporation into the clinical protocol is capable of overcoming the limitations of the traditional method, contributing to increased success rates in endodontic treatment.
Copyright (c) 2026 Vinicius Nascimento Oliveira, Vinicius Lages Guimarães https://creativecommons.org/licenses/by/4.0
Innovation in the Institutional Maturity of Public Universities: Limits and integration of organisational capabilities
Innovation in the context of Brazilian public universities manifests less as the result of adopting technologies or multiplying initiatives and more as an expression of the institutional capacity to articulate practices, processes and structures within organisational functioning. This article aims to analyse the role of innovation in institutional maturity, focusing on the limits and organisational conditions that shape its consolidation as an institutional practice. It adopts a qualitative analytical-conceptual approach, grounded in the articulation between specialised literature and the analysis of regulatory frameworks that influence the operation of public universities. The findings indicate that the presence of innovative initiatives does not necessarily imply their incorporation into institutional functioning, as situations of organisational fragmentation, weak coordination between units and difficulties in integrating information flows remain recurrent. The analysis of the regulatory framework shows that innovation develops within a regulated environment marked by requirements of control, transparency and standardisation, which condition its operationalisation. In this context, institutional maturity is not expressed by the number of initiatives, but by the capacity to integrate and sustain them over time. It is concluded that innovation depends on the articulation between organisational capabilities and normative requirements, being shaped by the forms of coordination and integration that structure institutional action.
Copyright (c) 2026 Claudiceia Silva Mendes, Renata Maria Abrantes Baracho Porto https://creativecommons.org/licenses/by/4.0
Community policing and proximity public security: An analysis of the effectiveness of the Ronda no Bairro Program in the municipality of Maceió, Alagoas, Brazil
The Programa Ronda no Bairro (PRB) is a public policy of proximity-based security in the State of Alagoas, aimed at violence prevention, the approximation between security forces and the community, social assistance, and the requalification of urban spaces. In Maceió, the program operates in strategic areas, such as Orla, Centro, Benedito Bentes, and Jacintinho, through integrated actions involving security agents, social teams, and public institutions. The general objective of this study was to propose a practical and scientifically grounded analysis of the feasibility and potential effects of implementing the Programa Ronda no Bairro in the Feirinha do Tabuleiro region, in Maceió. The methodological design adopted a qualitative approach, with exploratory and descriptive purposes, using bibliographic research, documentary research, statistical data collection, and an operational and financial feasibility study. The study analyzed aspects related to local criminality, the required operational structure, patrol modalities, estimated costs, and the integration between the PRB and the Military Police of the State of Alagoas (PMAL). The results indicate that implementing the PRB in Feirinha do Tabuleiro is operationally and financially feasible, with potential to reduce crime, increase the perception of security, requalify urban space, and strengthen the relationship between the police and the community. It is concluded that expanding the program to this locality represents a strategic alternative for improving proximity-based public security in Maceió.
Copyright (c) 2026 Bárbara Lôbo Gomes Vitorino https://creativecommons.org/licenses/by/4.0
Coenzyme Q10 supplementation in patients with heart failure: A literature review
Coenzyme Q10 (CoQ10), an antioxidant present in foods and synthesized endogenously, has been studied for its benefits on cardiac function. However, further research is needed to validate its recommendation as a non-pharmacological treatment for heart failure (HF). This study aims to conduct a narrative review of the literature from 2018 to 2024, regarding the use of CoQ10 as a supplement for patients with heart failure. A total of 236 articles were initially found, including clinical trials, single-center, and empirical studies on CoQ10 supplementation in HF, while duplicate and unrelated articles were excluded. After screening, four studies were selected for analysis. CoQ10 supplementation ranged from 300 mg/day (100 mg three times daily), 300 mg/day (single dose), up to 600 mg/day, with intervention periods ranging from 30 days to 2 years. Studies using a single daily dose ≥300 mg/day showed more evident benefits, indicating an increase in left ventricular ejection fraction (LVEF) and a reduction in NT-proBNP, improvements in the 6-minute walk test (6MWT), changes in the New York Heart Association (NYHA) functional classification, and a decrease in major adverse cardiovascular events (MACE) in the supplemented groups. Therefore, CoQ10 may be effective as a complementary therapy, helping to improve cardiac function and reduce adverse clinical outcomes in patients with heart failure. However, further studies are needed to consolidate scientific evidence and guide future recommendations in clinical guidelines.
Copyright (c) 2026 Inara Diniz Lourenço, Marcos Felipe Gonçalves dos Santos, Edimaira da Costa Oliveira, Thainá Araujo e Araujo, Lara Martins Lima, Patrícia Walker, Carlos Alberto Soares da Costa https://creativecommons.org/licenses/by/4.0
Epidemiological profile of chronic renal failure in Pernambuco: An analysis from 2017 to 2022
Introduction: Chronic kidney disease (CKD) is a disease that causes progressive and irreversible loss of kidney function, representing a global public health problem. Objective: To characterize the epidemiological profile of CKD in the state of Pernambuco from 2017 to 2022. Method: This is a quantitative, ecological, and descriptive time-series study using descriptive statistics with line graphs, column graphs, data classes, mean and standard deviation values, and statistical analysis of hospitalizations, deaths, and the quantity/expenses for hemodialysis collected from DATASUS. The variables were sex, race, and age group, and the data were analyzed for normality and presented as total, mean, and standard error. Results: Pernambuco had the seventh highest annual average in the Northeast for hospitalizations and hemodialysis. There were differences in hospitalizations across all age groups, with a prevalence among non-white men. Deaths and expenses for general hospital services were prevalent among non-white adult men. Hemodialysis costs and numbers were higher in men, and this difference was not observed with regard to race. Conclusion: This study highlights a profile of chronic kidney disease (CKD) incidence and access/hospital costs higher in non-white men. The mortality profile differs between pediatric and adult age groups, possibly due to the origin of CKD and its progression. However, after age 20, men are primarily responsible for high rates of hemodialysis and related costs, and non-white men die more frequently. These findings support more equitable health policies and broaden the basis for research on social and biological factors in CKD progression.
Copyright (c) 2026 Juliana Figueiredo Sobel, Barbara Michelle Monteiro Torreiro, Lorena Cordeiro de Almeida, Talyta Laís de Abreu Pereira, Fernanda Carolina Ribeiro Dias, Olávio Campos Júnior https://creativecommons.org/licenses/by/4.0
Regulariza Pará and the effectiveness of the Rural Environmental Registry for Traditional Peoples and Communities (CAR/PCT): Challenges and opportunities for environmental governance in the Amazon
The intensification of pressures on natural resources in the Brazilian Amazon highlights the need for effective environmental monitoring and control instruments capable of reconciling economic development with ecosystem conservation. In this context, the Rural Environmental Registry of Traditional Peoples and Communities (CAR/PCT), established by Law No. 12,651/2012, stands out as one of the main environmental management mechanisms aimed at regularizing rural properties in Brazil. This study aims to analyze the effectiveness of the CAR/PCT in the State of Pará, with emphasis on the actions of the Regulariza Pará Program, considering its role in promoting environmental governance in the Amazon. The research is characterized as qualitative, exploratory and descriptive in nature, based on documentary and normative analysis. The results indicate that the CAR/PCT represents a significant advance in environmental monitoring and the organization of territorial information, but its effectiveness depends on the institutional capacity for validating registries, the integration of systems, and the continuity of public policies. The experience of the quilombola territory of Cachoeira Porteira, in the municipality of Oriximiná, stands out as a pioneering case of the application of the CAR (Rural Environmental Registry) in collective territories, highlighting the importance of participatory methodologies, such as social cartography and community capacity building. It is concluded that the CAR/PCT (Rural Environmental Registry/Collective Territorial Plan) has high potential as an instrument of environmental governance, especially when associated with structured public policies and participatory approaches, being fundamental for the promotion of more inclusive and effective environmental management in the Amazon region.
Copyright (c) 2026 Layse Pereira Favacho da Rocha, Rodolpho Zahluth Bastos https://creativecommons.org/licenses/by/4.0
Playfulness in Early Childhood Education: Contributions to the development and learning of children aged 0 to 3 in Municipal Early Childhood Education Centers (CEMEI) in the municipality of Alegre, State of Espírito Santo (ES), Brazil
This article aims to analyze the role of play as a pedagogical strategy in the development and learning of children aged 0 to 3 years attending Municipal Early Childhood Education Centers (CEMEIs) in the municipality of Alegre/ES. It complements the articles in a line of research in early childhood education by the authors of this study. It is based on the assumption that play constitutes the language of childhood and a structuring element of educational practices in the first stage of Basic Education. The research is characterized as qualitative, of an empirical nature, carried out through the application of questionnaires, semi-structured interviews with teachers, and observation of pedagogical practices. The theoretical foundation is based on the contributions of Piaget, Vygotsky, Wallon, Kishimoto, Tardif, Nóvoa, and Andrade, articulated with the National Curriculum Guidelines for Early Childhood Education and the National Common Curriculum Base. The results indicate that playful practices favor engagement, autonomy, and the integral development of children; However, they highlight challenges related to teacher training and the structural conditions of the institutions. It is concluded that pedagogical intentionality and continuing education are decisive elements for consolidating play as a structuring axis of learning in early childhood.
Copyright (c) 2026 Eliane Angeli Bittencourt Peixoto, Camilla Viana de Souza Andrade https://creativecommons.org/licenses/by/4.0
Dental trauma in early childhood: A review and clinical perspectives
Dental trauma in deciduous teeth is a highly frequent clinical event, considered a public health problem by the World Health Organization (WHO). This injury, common in early childhood, requires rapid and appropriate management, since its consequences go beyond the aesthetic aspect, potentially compromising the germ of the successor permanent tooth and negatively impacting the child's oral and emotional quality of life. Given the need to update knowledge and support clinical practice, this study aimed to conduct a narrative literature review to consolidate information on the causes, consequences, and most appropriate clinical approaches for the treatment and prevention of dental trauma in the deciduous dentition. The review was conducted by searching renowned scientific databases such as PubMed/MEDLINE, SciELO, LILACS, and Google Scholar, using descriptors such as "dental trauma," "deciduous tooth," and "pediatric dentistry." The time frame encompassed articles published from 2002 to 2025. This study provides a comprehensive overview of the main types of injuries and their etiological factors, as well as highlighting the importance of immediate intervention by the dentist and parental guidance for a favorable prognosis. Ultimately, this study gathers and systematizes a compilation of scientific information aimed at optimizing the management of dental trauma cases in pediatric dentistry.
Copyright (c) 2026 Raissa Aparecida Aguiar Machado, Raissa Gomes de Oliveira, Renata Maria Colodette https://creativecommons.org/licenses/by/4.0
Pharmacotherapeutic monitoring of patients with COPD and/or asthma through telepharmacy: A scoping review
Telepharmacy is becoming a common practice worldwide, contributing to improved treatment adherence, rational use of medications, and the strengthening of patient self-care, especially during crises. This is a scoping literature review aimed at gathering evidence on the effectiveness and tools that can support the clinical practice of pharmaceutical care via telepharmacy for patients with Chronic Obstructive Pulmonary Disease (COPD) and asthma. The PubMed, Scopus, and Lilacs databases were used in conjunction with the descriptors "pharmaceutical care," "telepharmacy," "teleconsultation," "COPD," and "asthma," combined with Boolean operators to search for articles. Studies in Portuguese, English, Spanish, and French were included, without temporal restrictions, that addressed pharmaceutical interventions in patients with COPD or asthma via telepharmacy. After applying the selection and eligibility criteria, 10 articles were selected for final analysis. Pharmaceutical interventions performed through telepharmacy contribute to symptom control, treatment adherence, and improved inhalation technique. These findings reinforce the use of remote pharmaceutical care as a strategy to support the management of diseases such as COPD and asthma, and for populations that have difficulty accessing in-person care at health units. It is concluded that telepharmacy presents itself as a viable and promising tool for expanding the provision of pharmaceutical care, promoting adherence, correct execution of inhalation techniques, and disease control.
Copyright (c) 2026 Maria Aduclecia de Lima, Eronilson Benício Batista da Silva, Luciene Alves Moreira Marques https://creativecommons.org/licenses/by/4.0