The journal Research, Society and Development (abbreviated as Res. Soc. Dev.) is a multidisciplinary scientific publication focused on promoting the dissemination of knowledge, using scientific methodologies for social, scientific and technological development through the publication of manuscripts, results and conclusions of research, in the various areas of knowledge. It is a monthly online journal. Submissions are evaluated by peers (Double Blind Review) with experience in the area of ​​the manuscript. Ad hoc revisors 2025 We thank all of the more than 340 “ad hoc” reviewers who contributed to this Journal in their evaluations (double-blind peer review). Reviewers 2025
Authors who publish with this journal agree to the following terms: 1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. 2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. 3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
Salivary proteomic analysis for the early detection of smoking-related lesions: A narrative literature review
Smoking is considered a health hazard around the world, with high mortality rates and, above all, harmful consequences that manifest themselves years later. With the potential advances in the use of saliva, as it is a non-invasive, safe, and cheaper collection method for identifying the diagnosis of lesions caused by smoking through proteomic biomarkers, it is being considered a great attractive and useful tool for tests aimed at early results and reflecting the health of the human body. The article presents a qualitative literature review, with little structure and of the specific type of narrative literature review, addressing smoking and saliva, with the aim of detailing the descriptions of each marker that uses the human saliva proteome, showing with data the evidence of their effectiveness and results, also focusing on describing their advantages for use, in addition to discussing some challenges of research in this field.
Copyright (c) 2025 Maria Vitória Fortuna Macedo, Jéssica Karoline da Cunha, Ana Luiza do Rosário Palma, Daniel Lira Dias, Joyce Nascimento Santos https://creativecommons.org/licenses/by/4.0
Rational use of herbal medicines in public health: Safety, efficacy and health regulation
This study examines the role of herbal medicines in public health, addressing aspects of safety, efficacy, and health regulation, and highlighting the challenges and prospects for their safe integration into the health system. The use of herbal medicines has expanded in recent decades, driven by the appreciation of integrative and complementary practices and the recognition of the therapeutic potential of medicinal plants. In Brazil, the inclusion of these products in the Unified Health System (SUS) is achieved through specific public policies aimed at guaranteeing qualified, safe, and evidence-based access. This is a narrative literature review, covering the last ten years, based on national and international scientific articles, as well as official documents from the Ministry of Health and the National Health Surveillance Agency. The findings demonstrate that, while herbal medicines offer relevant clinical and socioeconomic benefits, their inappropriate use can lead to health risks, such as adverse reactions, drug interactions, and variations in product quality. Furthermore, the efficacy of many herbal medicines still lacks robust scientific evidence. It is concluded that promoting the rational use of herbal medicines requires strengthening health regulations, training health professionals, and expanding clinical research.
Copyright (c) 2026 Weryk Maranhão dos Santos, Mariana Araújo, Jânio Sousa Santos https://creativecommons.org/licenses/by/4.0
The influence of micronutrients on the recovery of soccer players: Narrative review
The physical demands of soccer involve high-intensity intermittent efforts, distances of 11-13 km per match, and the generation of reactive oxygen species (ROS). This scenario triggers oxidative stress, exercise-induced muscle damage (EIMD), inflammation, and delayed-onset muscle soreness (DOMS), compromising recovery within the short 48-72h intervals of the congested Brazilian calendar. This study aimed to synthesize scientific evidence regarding the impact of micronutrients on soccer players' recovery. A narrative review was conducted using PubMed and BVS databases, selecting primary studies published between 2020 and 2025 focusing on vitamins C, D, E, zinc, omega-3, and polyphenols in high-intensity athletes. Findings indicate that supplements such as vitamin C (1000 mg/day), vitamin D (6000 IU/day), curcumin (300-1400 mg/day), astaxanthin, beetroot, and chokeberry reduce markers of inflammation (IL-6, CRP), muscle damage (CK, LDH), and oxidative stress (MDA, 8-OHdG). Performance effects (VO2max and agility) were inconsistent, depending on initial redox status, dose, and duration. Excessive doses may inhibit physiological adaptations like mitochondrial biogenesis and hypertrophy. Results suggest that micronutrients optimize recovery when applied in a balanced and individualized manner. Specific guidelines are required in Brazil, where local protocols are lacking, justifying further research with larger samples and synergistic combinations to reduce reliance on anti-inflammatories and overtraining risks.
Copyright (c) 2026 Willan Caio Campos Rodrigues, Antonio Marcial Abud Ferreira Júnior, Lucas Thiago Vieira Paraguassu, Célio Carmelino Pinheiro Pinto Junior, Luísa Margareth Carneiro da Silva https://creativecommons.org/licenses/by/4.0
Nursing care for patients undergoing electroconvulsive therapy
Objective: to report the routine of the Nursing teams in the care of patients undergoing electroconvulsive therapy. Results: electroconvulsive therapy is a procedure performed in an outpatient surgery center for psychiatric treatments, being, in some cases, the last intervention in severe and refractory disorders. It is performed three times a week, from Monday to Friday, with a one-day break between sessions; 15 patients per day are scheduled. Due to COVID-19, there was a reduction to eight patients per day. The team is composed of Psychiatric and Surgical Nurses and Psychiatry and Anesthesiology doctors. The procedure requires specific safety measures, such as an eight-hour fast. Such care, typical of Nursing, gains special plot in severe psychiatric patients. Controlling the ingestion of food and water in globally disoriented patients and those at risk of aggression due to delirium is only one of the challenges. The procedure is only performed after the conditions of relaxation and anesthesia have been met with the release of the electromagnetic wave stimulation. The main complications in the recovery room are related to hypoventilation. Final considerations: it is important to emphasize the importance of Nursing in terms of the integrality of care, evidenced by its continuous presence before, during and after the performance of this procedure.
Copyright (c) 2021 Ana Karina Silva da Rocha Tanaka; Adriana Maria Alexandre Henriques; Ana Maria Pagliarini; Alan Cristian Rodrigues Jorge; Lisiane Paula Sordi Matzenbacher; Rosaura Soares Paczek https://creativecommons.org/licenses/by/4.0
The role of psilocybin as an adjuvant treatment for resistant major depressive disorder: An integrative literature review
Introduction: Treatment-resistant Major Depressive Disorder (TR-MDD) represents a significant clinical challenge, affecting patients who do not respond adequately to multiple conventional therapeutic approaches. In recent years, psychedelic substances such as psilocybin have emerged as promising alternatives in the adjunctive management of resistant depression, generating increasing scientific interest. Objective: To critically analyze the current evidence on the efficacy and safety of psilocybin as an adjunctive treatment for treatment-resistant major depressive disorder. Materials and Methods: The research methodology used was an integrative literature review. The PICO strategy was applied to formulate the guiding research question. In addition, a cross-search of the descriptors “Treatment-Resistant Depressive Disorder”; “Adjunctive Pharmacological Therapy”; “Psilocybin” was performed in the following databases: National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar, and the Virtual Health Library (VHL). Results and Discussion: Recent clinical studies show that psilocybin, when administered in a controlled setting and accompanied by psychotherapeutic support, promotes rapid and sustained antidepressant responses in patients with TR-MDD. Its effects appear to be related to the modulation of brain connectivity and the induction of intense subjective experiences, which favor cognitive-affective restructuring. Reported adverse events are generally mild to moderate and self-limited, underscoring the importance of qualified professional supervision. Conclusion: Psilocybin represents an innovative and promising approach as an adjunctive therapy for TR-MDD. Despite encouraging results, further studies are necessary to consolidate its safety, standardize protocols, and expand its responsible clinical use.
Copyright (c) 2026 Davi Carneiro Vidigal, Maria Fernanda Maia de Paiva Ferreira, Rodolfo Souza de Faria https://creativecommons.org/licenses/by/4.0
Between screens and diagnoses: Delivering bad news to cancer patients in telemedicine
This review aimed to evaluate and demonstrate the impact of telemedicine on delivering bad news, especially to cancer patients. It is a narrative literature review, in which 21 articles were selected from the BVS and PubMed databases. The results showed that the use of telemedicine for communicating bad news in oncology contexts has had several repercussions on care and the doctor-patient relationship. Limitations were highlighted, such as difficulties in welcoming patients and connection failures, as well as benefits, such as multidisciplinary presence and reduction of geographical barriers. Consequently, this resource has been widely applied recently, with several adaptations, such as improvements to communication protocols. Thus, it can be inferred that remote communication, despite still facing challenges, is a tool with significant advantages in the field of oncology. Thus, it is noted that the combination of in-person and virtual models, in addition to improved professional training and refined protocols, can maintain the quality and humanization of care.
Copyright (c) 2026 Júlia Nogueira Mourão, Láisla Lima Nogueira, Júlia Mara Resende Abreu, Lúcio Aparecido Moreira https://creativecommons.org/licenses/by/4.0
Trisomy 21 and the subject of language: Its constitution through orality
This article aims to reflect on orality in Trisomy 21 (T21) as a space for the constitution of the subject of language, considering the processes of signification that emerge in mediated social interactions. It is based on assumptions from Historical-Cultural Theory, Enunciation Theory, and Discursive Neurolinguistics, perspectives that understand language as a social practice and the subject as constituted in and by enunciative-discursive processes. Methodologically, this is a qualitative, exploratory research that articulates a literature review with the analysis of empirical data. The data analyzed refers to an enunciative-discursive situation involving a child with T21, which was transcribed and interpreted in light of the theoretical-methodological framework of Discursive Neurolinguistics. The results show that, although the orality of the subject with T21 may present discontinuities and unconventional organization, it is traversed by meanings, intentionalities, and marks of subjectivation. It is observed that the interlocutor's mediation plays a central role in the reorganization of speech, enabling advances in the construction of statements with marking of person, time, and space. It is concluded that orality, when understood as a mediated social practice, constitutes a privileged space for meaning-making and the emergence of the subject of language, reaffirming that biological factors do not absolutely determine the linguistic development of people with Down syndrome (Trisomy 21).
Copyright (c) 2026 Emanuelle de Souza Silva Almeida, Rayana Thyara de Lima Rêgo Ladeia, Jaqueline Almeida Silva, Fernanda Marcelle Souza Almeida, Carla Salati Almeida Ghirello-Pires https://creativecommons.org/licenses/by/4.0
The influence of social media on body image perception and the development of eating disorders: An integrative review
Considering the growing prevalence of body dissatisfaction and the widespread dissemination of unattainable aesthetic standards on social media, which can act as a significant risk factor for the development of Eating Disorders (ED), this research had the general objective to analyze, through an integrative literature review, the relationship between the use of social networks and changes in body image and eating behavior. To this end, an Integrative Literature Review was performed, using the PubMed and BVS databases to select primary studies published between January 2020 and July 2025. Thus, it was observed that the non-critical use of social networks is consistently associated with body dissatisfaction and the risk of ED. Mechanisms such as upward comparison and the action of algorithms creating "echo chambers" intensify symptoms, directing toxic content. The influence is manifested in the search for thinness (in women) and muscularity (in men, with risk of Muscle Dysmorphia), with young Instagram and TikTok users being the most vulnerable. It is concluded that social networks exert a significant and complex influence on self-image, posing a public health challenge that demands preventive strategies and conscious use of the platforms.
Copyright (c) 2026 Antonio Marcial Abud Ferreira Junior, Célio Carmelino Pinheiro Pinto Junior, Lucas Thiago Vieira Paraguassu, Willan Caio Campos Rodrigues, Luísa Margareth Carneiro da Silva https://creativecommons.org/licenses/by/4.0
Glucose and insulin: Case report and review of congenital hyperinsulinism
Introduction: Hypoglycaemia is a condition in which plasma glucose concentration falls below normal levels and can have transient or persistent causes. Among the persistent causes, congenital hyperinsulinism (CHI) stands out, a rare endocrine disorder resulting from genetic mutations, with an incidence of approximately 1:25,000-50,000 live births and a high risk of sudden death. Symptoms include hypoglycaemia in association with laboratory abnormalities such as elevated C-peptides, high insulin, negative ketonemia and reduced fatty acids in association with specific genetic mutations. Treatment includes pharmacological approaches that may escalate to surgical approaches. Objective: To report a rare case of congenital hyperinsulinism, describing in detail its diagnosis, treatment, and consequences associated with the disease. Methods: This is a descriptive, retrospective observational study of a single individual (n=1) without statistical analysis, but with a review of the literature. Conclusion: The report will highlight the importance of early recognition, laboratory evaluation, and therapeutic approach, contributing to knowledge about this rare condition.
Copyright (c) 2026 Tauane Eduarda Kirch, Ana Carolina Pereira Meneguite https://creativecommons.org/licenses/by/4.0
Relationship between medication and prognosis in patients with juvenile myoclonic epilepsy
Juvenile Myoclonic Epilepsy (JME) is a genetically determined idiopathic generalized epilepsy, which accounts for 5-11% among all patients with epilepsy. JME is characterized by seizures that begin in adolescence and are easily controlled with medication, but persist permanently. Often without related structural causes, however, the classic precipitating factors are sleep deprivation, stress, menstruation, fatigue and alcohol consumption. The present study aims to describe the relationship between medications and prognosis in patients with JME, in addition to correlating medication classes with the quality of life of these patients, being structured in a bibliographical review, of an integrative and qualitative type, of free and complete articles. of systematic reviews and meta-analysis, published between 2019 and 2024, in English, Spanish and Portuguese, collected in the PubMed and SciELO databases. There is a need to carry out new studies that highlight the relationship between medications recommended for JME and their prognosis, aiming to improve the patient's quality of life.
Anna Perazzo Correia de Araújo Varjal Câmara
Copyright (c) 2026 Anna Perazzo Correia de Araújo Varjal Câmara, Augusto França Cruz Ximenes, Giovanna Maria Melo Vieira, Juliana Oliveira Diniz, Letícia Antero Fernandes, Silvia Ferreira Gadelha Mendes, Wagner Gonçalves Horta https://creativecommons.org/licenses/by/4.0
Learning style inventory for Nursing Technicians: Adaptation, validation and application of instrument
Technical education in Nursing is strategic for qualifying the health workforce in Brazil. Recognizing and valuing students' Learning Styles can make pedagogical processes more effective and inclusive, aligned with the training needs of these professionals. The study aimed to construct, validate and apply an instrument to identify the Learning Styles of Nursing Technicians, based on the Felder and Soloman model. Methodological research, with a quantitative approach, developed in five stages: (1) adaptation of items and analysis by judges, (2) analysis of internal consistency, (3) preparation of the instrument and answer sheet, (4) pre-test with 17 students and (5) application with 192 nursing technicians registered in COREN-SP. Cronbach's Alpha was used to assess data reliability. The Nursing Learning Styles Inventory (IEA-Enf) demonstrated satisfactory internal consistency. The most prevalent styles were Sequential Understanding (61.95%), Sensory Perception (60.07%) and Active Processing (57.81%), indicating a preference for logical organization, practical application of knowledge and collaborative activities. The lowest averages were found in the Global Understanding, Intuitive Perception and Reflective Processing styles. Subtle differences in styles were also observed according to gender, age and type of educational institution. The IEA-Enf proved to be a valid instrument and appropriate to the reality of technical education in Nursing, contributing to the personalization of pedagogical strategies. Its use can assist teachers in the construction of more inclusive and effective educational practices. Among the limitations of the study, the sample restricted to the city of São Paulo and the collection via a digital platform stand out.
Francisco Rosemiro Guimarães Ximenes Neto
Copyright (c) 2026 Etelvina Vitor Santos, Isabel Cristina Kowal Olm Cunha, Francisco Rosemiro Guimarães Ximenes Neto https://creativecommons.org/licenses/by/4.0
Ultrasound-assisted extraction and characterization of bioactive compounds from ‘Rosa’ mango (Mangifera indica L.) pomac
The generation of agro-industrial residues from the processing of tropical fruits has increased, representing an environmental and economic challenge. This study aimed to evaluate the potential valorization of ‘Rosa’ mango pomace as a source of bioactive compounds through the application of different extraction methods and the physicochemical and bioactive characterization of the obtained extract. Samples were processed at the Agroindustrial Processes Laboratory of Embrapa Agroindústria Tropical, where mangoes were peeled, ground, and filtered, and the resulting pomace was used as raw material. The ultrasound-assisted extract was selected for analysis due to its higher color intensity. Physicochemical parameters, including pH, total titratable acidity, and total soluble solids, were determined, as well as the quantification of yellow flavonoids, anthocyanins, and vitamin C using spectrophotometric methods. The extract showed an acidic pH (4.36), low titratable acidity (0.08 g citric acid/100 g), and low total soluble solids content (4.2 °Brix), characteristics compatible with diluted mango-derived products. The presence of yellow flavonoids (7.05 mg/100 g) and anthocyanins (0.54) indicated the extraction of phenolic compounds with antioxidant potential. Vitamin C content was low (0.365 mg/100 g), possibly due to dilution and the sensitivity of ascorbic acid to the extraction process. It is concluded that ‘Rosa’ mango pomace presents potential for valorization as a source of bioactive compounds, demonstrating feasibility for the sustainable reuse of agro-industrial residues and value addition to mango processing by-products within agroindustrial chains.
Copyright (c) 2026 Kauê Pinto de Souza, Thais Carvalho Freitas Damasceno, Stefany Pires de Lima, Maria Milena Barros Silva, Lucicléia Barros de Vasconcelos, Vanderson da Silva Costa https://creativecommons.org/licenses/by/4.0
Biological maturation, training load, and injury risk in youth soccer: An integrative review on performance, exercise-induced adaptations, and safe sport development strategies in young athletes
This integrative review aimed to analyze the influence of biological maturation on training load prescription and injury risk in youth soccer athletes. The literature search was conducted in the PubMed, SciELO, and LILACS databases, including studies published between 2015 and 2025, with samples composed of male athletes from the U-11 to U-23 categories. A total of 31 studies were included, addressing physiological, biomechanical, and perceptual aspects related to maturational stage. The findings indicate that maturation significantly impacts neuromuscular responses, training adaptations, perceived exertion, and injury susceptibility. The circa-PHV period was identified as a critical window, requiring strict load management and individualized exercise protocols. Strategies such as bio-banding, maturational classification, and load adjustments based on both subjective and objective indicators proved effective in mitigating risks and optimizing long-term athletic development. It is concluded that considering maturational stage is essential for safe and effective training prescription and should replace approaches based solely on chronological age in youth soccer contexts.
Copyright (c) 2026 Victor Vicente, Thiago Fernando Lourenço https://creativecommons.org/licenses/by/4.0
From atom to zebra: An approach to the levels of organization of living beings through Cordel Literature
Contemporary education faces significant challenges, particularly with regard to the search for innovative teaching strategies in Biology education. The use of pedagogical practices that articulate science and art is highly important for the development of the teaching–learning process in this field. In this context, the objective of this study was to analyze the use of cordel literature as a didactic tool in addressing the topic of levels of organization of living beings. The study was conducted with students from the Federal Institute of Pernambuco (IFPE), within the Environmental Management subject of the Technical Course in Hospitality. The proposed activity was carried out in three stages: i) introduction of the topic through the recitation of a cordel pamphlet; ii) discussion of the theme based on a revisitation of each stanza of the cordel; and iii) evaluation of the proposal by the participants. The analysis of the results showed that the use of cordel literature increased student engagement, fostering active participation in the activity. The rhythmic and imagistic characteristics of the cordel contributed to memorization and to the conceptual organization of the content addressed. Therefore, cordel literature is considered an effective didactic resource for approaching topics related to Biology.
Copyright (c) 2026 Edmilson Clarindo de Siqueira https://creativecommons.org/licenses/by/4.0
Revisional bariatric surgery for conversion to gastric bypass after primary vertical gastroplasty and gastroesophageal reflux disease - A retrospective cohort study from a general surgery service
Obesity is a chronic multifactorial disease associated with increased morbidity and mortality, as well as metabolic and gastrointestinal comorbidities, including gastroesophageal reflux disease (GERD). Bariatric surgery is the most effective treatment for severe obesity, with sleeve gastrectomy and Roux-en-Y gastric bypass being the most commonly performed procedures. However, long-term limitations of sleeve gastrectomy, such as weight regain and worsening GERD, have increased the demand for revisional surgery. This retrospective study analyzed patients who underwent sleeve gastrectomy between 2015 and 2022 in Rio de Janeiro, focusing on the need for conversion to gastric bypass. The cohort showed a predominance of female patients, a mean age of 37 years, and a mean initial BMI of 44.2 kg/m². Approximately 9.7% required revisional surgery, mainly due to refractory GERD and weight regain. Conversion to gastric bypass resulted in significant improvement in reflux symptoms and sustained weight loss. Gastric bypass proved to be a safe and effective revisional option.
Copyright (c) 2026 Luigi Demetrio Romero Bravo, Guilherme Lemos Cotta Pereira, Kimberlli de Seixas Nunes, Gabrielle Vaz de Azevedo David, René Fernando Catillo Guamán, Fabián Mateo Ávila Orellana https://creativecommons.org/licenses/by/4.0
Copyright (c) 2026 Ricardo Shitsuka https://creativecommons.org/licenses/by/4.0
Scientific articles, from any field of knowledge, are scientific documents that support, in some way, the informal and formal teaching and learning processes of those who produce them, those who read them, and those who participate in the editorial processes. Therefore, our mission is important in the sense of being part of the dissemination of data, information, knowledge, and wisdom for a better society and for the development of a better society. In 2025, we published volume 14 with 12 issues. We thank everyone who contributed to the editorial work with ethics and respect for all: readers, authors, editorial team, reviewers, and everyone without exception.
Lifestyle of people with Diabetes mellitus in Primary Health Care
This study aims to disclose the lifestyle profile of people with diabetes, who are assisted in a Family Health Strategy (ESF) unit. This is a quantitative, exploratory, survey-type study. For data collection, a questionnaire called “Fantastic Lifestyle” was used, which had, as a non-probabilistic sample, 59 participants with Type 1 and Type 2 Diabetes Mellitus (DM). negative impact was on alcohol and tobacco, which had the respective averages of 3.88 and 3.31. In relation to the domains that should occur changes in lifestyle are: physical and behavioral activities, these presented an average of 1.14 and 2.05. Thus, DM is a pathology that affects a large part of the world's population. Thus, carriers of this disease must be shown that, with the practice of regular physical activities and a healthy diet, it is possible for them to have a better quality of life.
Noncommunicable Chronic Diseases (CNCD).
Copyright (c) 2023 Roberta Divina de Sousa Lima; Sara Ferreira Resende; Marcelle Aparecida de Barros Junqueira; Gabriel da Cruz Santos; Aryelle da Costa Batista da Luz; Fernanda Ferreira Amuy https://creativecommons.org/licenses/by/4.0
The contributions of play to the teaching and learning of Mathematics
Public education in some schools in Brazil is quite efficient when using playful tools as a means of presenting the content of existing subjects in secondary education, especially in mathematics teaching. Thus, the objective of this study is to analyze the contributions of play to the teaching and learning of mathematics in the school environment. Specific objectives: To contextualize play and its function in relation to teaching and learning; to highlight the teaching of mathematics and play; to show the contributions of play to the subject of mathematics in secondary education. Methodology: This is a qualitative narrative review. According to the study, play-based learning is considered by both teachers and students to be a very effective tool for addressing students' difficulties in various subjects, including mathematics. However, it still faces resistance from both teachers and some students. The lack of support from school administrators regarding the necessary resources to implement play-based learning in the classroom appears to be one of the difficulties in carrying out these activities in the school environment. Thus, when discussing the use of play-based learning in subjects to alleviate learning difficulties, it can be a supportive tool for teachers working with their high school students. However, it requires greater adoption and ongoing training for teachers to develop play-based activities more effectively.
Copyright (c) 2026 Juliene Almeida dos Santos Nascimento https://creativecommons.org/licenses/by/4.0
Social Work and algorithmic decision-making: The use of artificial intelligence in judicial promotion and protection proceedings
In Portugal, the decision-making of judicial magistrates in legal proceedings for promotion and protection is based, in particular, on the work of social workers from the Multidisciplinary Court Advisory Teams (EMAT), who are responsible, for example, for preparing reports and social information and are subject to evident pressure to reach the best decisions regarding the situation of the child or young person. Artificial intelligence (AI) is presented as a resource to ensure greater efficiency in the decision-making process of social workers. However, using this technology to prepare reports or social information accepted as evidence in judicial proceedings for promotion and protection raises legitimate concerns about the impact of AI on judicial decisions. In this article, we aim to demonstrate that, although it is possible to use an AI platform to prepare a social report in the context of a promotion and protection case, the use of this type of technology calls into question the decision-making of judicial magistrates and, consequently, the administration of justice. We conclude that the inability to reconstruct the path taken by the judge to reach a decision, as well as the difficulty in explaining their reasoning, which may be compromised by evidence produced by AI, threatens the impartiality and independence of judicial decisions, in accordance with national and international legal instruments. We believe that the use of AI by judicial actors must necessarily preserve all mechanisms that allow for the control and scrutiny of the decision-making process by the judicial magistrate.
Copyright (c) 2026 Gonçalo Mota https://creativecommons.org/licenses/by/4.0
Anxiety, the COVID-19 pandemic, and the increased of bruxism and temporomandibular disorders: Literature review
The pandemic context, marked by social isolation, financial insecurity, social pressure, and fear of COVID-19, generated a significant increase in stress, anxiety, and depression, conditions that directly affect oral health, especially in the development of bruxism and temporomandibular disorders. These disorders, associated with emotional conditions, affect the quality of life of the population and can cause muscle pain, tooth wear, and functional limitations. This study reviews the literature to assess the increase in cases of bruxism and temporomandibular disorders (TMD) as a result of the psychological problems caused by the COVID-19 pandemic. The bibliographic research was conducted between January and February 2025, with data collected from databases such as LILACS, BVS, PubMed, and SciELO, using the descriptors "bruxism," "TMD," "COVID-19," and "incidence." A total of 31 articles were initially selected, but after applying inclusion and exclusion criteria, 15 were chosen. The analyzed studies show that the worsening of the population's emotional state during the COVID-19 pandemic had a direct impact on oral health, with an increased prevalence of bruxism and TMD symptoms, especially among those who experienced higher levels of anxiety and depression. Among students and healthcare professionals, an increasing incidence of sleep and awake bruxism was observed, both related to stress. It is concluded that the COVID-19 pandemic directly exacerbated factors such as anxiety, stress, and bruxism (psychosocial factors), resulting in a higher incidence of bruxism and TMD, highlighting the need for preventive and treatment interventions for these problems.
Copyright (c) 2026 Carla Vitória Mota Cavalcante Lima, Thalleyldson dos Santos Ramos, Sandra Augusta de Moura Leite, Maria Áurea Lira Feitosa, Rosana Costa Casanovas https://creativecommons.org/licenses/by/4.0
Brazilian panorama of pedagogical practices and challenges of Environmental Education in the context of Conservation Units
Este estudo analisa as práticas pedagógicas em educação ambiental desenvolvidas em um contexto de Unidades de Conservação no Brasil, com foco nas experiências realizadas. O objetivo foi identificar as categorias de práticas pedagógicas mais recorrentes, os tipos de estudos realizados, a distribuição geográfica por bioma e os desafios enfrentados na implementação dessas práticas. A pesquisa foi baseada em uma revisão de estudos publicados entre 2004 e 2024, localizados por meio de busca em bases de dados como Scopus, Web of Science e o Portal de Periódicos da CAPES. A metodologia envolveu uma análise documental quantitativa e qualitativa através da técnica de análise de conteúdo, com a criação de categorias temáticas a partir da leitura dos textos selecionados. Os dados foram organizados em gráficos para facilitar a visualização dos resultados. A análise apresentou 12 categorias de práticas pedagógicas. Além disso, identificou-se a distribuição das práticas em diferentes biomas do Brasil, evidenciando desigualdades e desafios específicos, como a falta de recursos, capacitação de educadores e resistência institucional. Conclui-se que, apesar da diversidade e inovação nas práticas, há lacunas consideráveis na implementação dessas práticas de educação ambiental em um contexto de Unidades de Conservação.
Copyright (c) 2026 Rosinaldo Ferreira dos Santos, Maria Mirtes Cortinhas dos Santos https://creativecommons.org/licenses/by/4.0
Perinatal programming and risk of chronic diseases: Metabolic, cardiovascular, renal, and neuroimmune impacts in adulthood
The perinatal period spans from conception to the seventh day after delivery, being a period of fetal formation whose influences can have repercussions in postnatal life. A biologically critical phase, in which adaptive mechanisms mediated by epigenetic, metabolic, hormonal, and inflammatory processes durably shape the functionality of organic systems. Perturbations during this interval, including prematurity, intrauterine growth restriction (IUGR), maternal metabolic dysfunctions, alterations in the microbiota, and environmental exposures can impact renal, cardiovascular, pulmonary, neuroendocrine, and immunometabolic maturation, posing a risk for the development of chronic diseases throughout life, such as Diabetes Mellitus (DM), Systemic Arterial Hypertension (SAH), and Chronic Kidney Disease (CKD) may occur. This study aimed to describe the most impactful influences during pregnancy and early postnatal life and their consequences in adult life. An integrative review was conducted, with articles from 2020 to 2025, in the PubMed database, in the English language, with the keywords: Perinatal Care, Chronic Disease, and Chronic Kidney Disease. Emphasis is placed on the biological mechanisms underlying adverse fetal programming, with a focus on the interfaces between metabolism, hemodynamics, inflammation, and cellular signaling. The results reinforce that the perinatal environment acts as a fundamental determinant of adult health, highlighting the need for preventive strategies aimed at metabolic and environmental protection of the pregnant woman and newborn. Prematurity, IUGR, low birth weight, maternal obesity, and maternal DM are the main agents that impact the perinatal environment and increase the risk for chronic diseases, mainly DM, SAH, CKD, and obesity.
Copyright (c) 2026 Isabela Rocha Ribeiro, João Pedro Silva Alves, Gilson Fernandes Ruivo https://creativecommons.org/licenses/by/4.0
Identification and biotechnological potential of cellulases-producing rhizobacteria from the Amazon rhizosphere
The Amazon rainforest hosts an extraordinary microbial diversity with significant yet underexplored biotechnological potential. This study aimed to identify and evaluate the production of endoglucanase, β-glucosidases and CMCase rhizobacteria isolated from the rhizosphere of Pueraria phaseoloides and Inga edulis, focusing on strains with potential applications in lignocellulosic biomass conversion. A total of 50 rhizobacterial isolates were reactivated and screened for cellulolytic activity using carboxymethylcellulose (CMC) agar. Thirty-one isolates (62%) formed hydrolysis halos, and 22 strains exhibited an enzymatic index (EI) ≥ 2.0, indicating high cellulolytic potential. Statistical analysis revealed significant differences between host plants, with isolates from P. phaseoloides showing higher average EI values than those from I. edulis. Molecular identification of the most active isolates (EI ≥ 2.0) revealed strains belonging to the genus Bacillus, including Bacillus subtilis and Bacillus velezensis. The strain B. subtilis INPA R-583, which showed the highest EI, was selected for enzymatic characterization. Kinetic analyses demonstrated stable and high endoglucanase (CMCase) activity, increasing β-glucosidase activity at later cultivation stages, and relatively low total cellulase (FPase) activity. These results indicate a functional but incomplete cellulolytic system, with strong potential for applications requiring endoglucanase activity. Overall, the findings highlight the Amazon rhizosphere as a valuable reservoir of cellulolytic bacteria and support the biotechnological relevance of native rhizobacteria for sustainable biomass conversion processes.
Copyright (c) 2026 Matheus Montefusco, Enide Luciana Belmont-Montefusco, Maria Julia Pessoa Brandão, Luiz Antonio de Oliveira https://creativecommons.org/licenses/by/4.0
Quality of brazilian beef exports: Analysis of recent data and regulatory challenges
Brazil is one of the leading exporters of beef in the international market, with China accounting for approximately 48% of the exported volume, followed by the United States, Chile, the European Union, Russia, and Mexico. This scenario highlights the strong dependence on the Chinese market, while also indicating the gradual diversification of destinations for Brazilian beef. The sector faces challenges related to tariff and non-tariff barriers, including strict sanitary requirements, traceability, and animal welfare standards. This study aimed to analyze the main markets for Brazilian beef, considering export performance, regulatory requirements, trade barriers, and sectoral trends. The research was based on a bibliographic and documentary survey, including data from the USDA, FSIS, MAPA, ABIEC, FAO, and RASFF, as well as academic articles addressing competitiveness and supply chain dynamics. The analysis indicated a reduction in RASFF alerts between 2024 and 2025, reflecting advances in food safety. However, the United States maintains significant tariff barriers, which negatively impact competitiveness. It was concluded that, although Brazil presents favorable conditions to maintain its international relevance in the sector, investments in traceability, technological innovation, sustainability, and market diversification are essential to expand access and consolidate its position in the global market.
Copyright (c) 2026 Yan Lucas Matias Viana, Denise R. Perdomo Azeredo https://creativecommons.org/licenses/by/4.0
Biological and behavioral determinants of early childhood caries: Recent evidence
Introduction: Early Childhood Caries (ECC) is a multifactorial condition resulting from the interaction of biological, behavioral, dietary, and microbiological factors. Changes in salivary pH, flow rate, and buffering capacity directly influence the balance between enamel demineralization and remineralization, thereby modulating disease risk. In parallel, diets rich in sucrose favor the acid metabolism of Streptococcus mutans and Lactobacillus spp., the main bacteria associated with caries. This article aims to compile and analyze recent evidence on the biological (saliva, pH, buffering capacity, microbiome) and behavioral (diet, hygiene, habits) determinants involved in ECC, highlighting their implications for clinical practice in Pediatric Dentistry. Methodology: This review brings together recent studies that investigate the biological and behavioral determinants of early childhood caries, emphasizing the role of saliva, the oral microbiome, and diet as central factors in the etiology of the disease. Results and Discussion: The results of this review confirm that early childhood caries is a multifactorial condition arising from the dynamic interaction between biological, behavioral, and environmental factors. Findings related to salivary pH, buffering capacity, salivary flow, cariogenic diet, and the microbiome show significant consistency with what has been widely discussed in the international literature. Final Considerations: It is concluded that understanding the determinants of early childhood caries is essential for clinical practice in Pediatric Dentistry. The literature analyzed indicates that reducing caries prevalence depends primarily on early, educational interventions capable of modifying behaviors and restoring the ecological balance of the oral cavity.
Copyright (c) 2026 Suzany Ferreira da Silva, Mônica Echilly Alves de Sousa, Fernanda Kelly Alves do Bonfim, Jeovana Santos de Oliveira, Ádylla de Oliveira Silva, Nattalia Medeiros Soares, Ayla Thayná da Silva Costa, Kimberly Lais Gomes Santos, Ana Vitória Andrade dos Santos, Letícia Rosalie Santos da Silva, Alessa Izis Souza da Silva Melo, Bruno Almeida Dias, Filipe Bonfim Nunes, Camilla Thaís Duarte Brasileiro https://creativecommons.org/licenses/by/4.0
Limitations encountered by healthcare professionals in the care of indigenous patients: A scoping review protocol
Objective: map and identify the evidence available in the scientific literature regarding the limitations encountered by health professionals in providing care to indigenous patients. Methodology: this is a scoping review protocol conducted in accordance with the recommendations of the Joanna Briggs Institute (JBI) and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols - extension for scoping reviews (PRISMA-ScR) for the preparation of scoping reviews. Original articles, theses, and dissertations will be included. The search for the study sample will be conducted in the LILACS, PubMed, SciELO databases and in the gray literature, through the Thesis and Dissertation Catalog of the Coordination for the Improvement of Higher Education Personnel (CAPES), without time limits or language restrictions. A search strategy was developed for LILACS and adapted for other databases. The articles will be selected by title and abstract by two independent reviewers, using Rayyan software to manage the materials. The full texts of the included articles will be read and analyzed according to eligibility criteria. Data will be extracted from the selected articles using a standardized form. Expected outcome: the results will be presented in a flowchart and narrative summary, according to PRISMA-ScR guidelines, and will present the main difficulties and limitations encountered by health professionals in providing care to indigenous patients. Final considerations: the study provides a detailed description of the stages of the intended scope review, which will enable mapping of the literature on the subject, since the protocol presents an appropriate methodology and follows all scientific precepts and rigor.
Copyright (c) 2026 Arthur Alexandrino, Cauan Barbosa Nery, Mariana Silva Souza, Bruno Passos Pizzi, Gracia Maria de Miranda Gondim https://creativecommons.org/licenses/by/4.0
Analysis of urban occupation in an Environmental Interest Zone
Interest in wooded areas within the urban perimeter has led to the need to analyze urban occupation and environmental zoning areas in the North and West administrative regions of Cuiabá. This article aims to analyze the North and West administrative regions of Cuiabá (MT) in the year 2025, focusing on verifying the conformity of occupation in ZIA1, ZIA2, and ZIA3 zones and protected areas using geoprocessing to understand the environmental problem. Geotechnologies were used with analysis of satellite images in February 2025, with vectorization of built-up areas and cross-referencing with urban planning parameters. The methodology allowed the identification of occupations in ZIA zones, and the results point to the consolidation of occupations in locations that should be protected, revealing flaws in the effectiveness of the intended public protection policies.
Copyright (c) 2026 Noelto da Cruz Teixeira, Geraldo Antônio Gomes de Almeida, Thiago Moraes Ribeiro, Lene Ferreira de Miranda, Alex da Silva Agra https://creativecommons.org/licenses/by/4.0
Relationship between mental health and oral lesions: Recent evidence among university students
Introduction: The mental health of university students has been the subject of increasing attention, the increase in stress, anxiety, and depression among university students has direct repercussions on oral health due to neuroendocrine, immunological, and behavioral changes. This study aims to critically synthesize recent evidence regarding the relationship between mental health — with an emphasis on stress, anxiety, and depression — and oral lesions among university students, discussing their pathophysiological mechanisms, prevalence, clinical interactions, and implications for dental practice. Methodology: The present study consists of an integrative literature review, a method that enables the synthesis of evidence from studies with different methodological approaches. This design was chosen to allow a broad and multifactorial understanding of the relationship between mental health and oral lesions in university students. Results: There is a consistent association between psychological distress and oral manifestations in university students, especially temporomandibular disorders, bruxism, herpes simplex, and recurrent aphthous ulcers. These conditions result from stress-induced immunological and behavioral changes, with a negative impact on quality of life and academic performance. Discussion: Psychological distress among university students is directly associated with oral manifestations such as temporomandibular disorders, bruxism, herpes simplex, and recurrent aphthous ulcers. These findings reinforce the importance of early recognition and an interdisciplinary approach. Conclusion: It is concluded that stress, anxiety, and depression are strongly associated with oral manifestations in university students through biological and behavioral mechanisms. Early recognition of these alterations and an interdisciplinary approach are essential to promote comprehensive care and improve quality of life and academic performance.
Copyright (c) 2026 Ádylla de Oliveira Silva, Alessa Izis Souza da Silva Melo, Gabriela Santos Borges, Ana Vitória Andrade dos Santos, Mônica Echilly Alves de Sousa, Filipe Bonfim Nunes, Bruno Almeida Dias, Camilla Thaís Duarte Brasileiro https://creativecommons.org/licenses/by/4.0
Study of the use of zoledronic acid in pediatric patients with osteogenesis imperfecta at the Fernandes Figueira Institute (IFF/Fiocruz)
Osteogenesis Imperfecta (OI) is a rare genetic disorder characterized by bone fragility and wide clinical variability. This study aimed to evaluate the use of zoledronic acid in pediatric patients with OI treated at the Fernandes Figueira Institute (IFF/Fiocruz), describing the clinical profile, therapeutic response, and safety. This retrospective study was conducted between April 2024 and August 2025 and was based on the medical record review of 40 patients aged 2 to 18 years. An equal distribution between sexes was observed, with higher frequency of OI types I, IV, and III. Intravenous pamidronate was the most frequently used initial bisphosphonate, followed by oral alendronate as a transition strategy, while zoledronic acid was subsequently incorporated into the therapeutic regimen of all patients. Adverse events were more common with pamidronate (32.5%) than with zoledronic acid (17.5%), including fever, bone pain, headache, and gastrointestinal symptoms. Before zoledronic acid use, all patients had a history of fractures; after its introduction, only 12.5% reported new episodes, demonstrating a marked reduction. Subjective perception of clinical improvement was recorded in 7.5% of patients. NTX (n=3) and DEXA (n=2) results were insufficient for conclusions regarding bone remodeling or mineral density. Despite limitations related to the scarcity of complementary exams, the findings suggest clinical benefit of zoledronic acid, reinforcing its potential to reduce fractures and improve OI management in pediatric patients within the Brazilian public health context.
Lion Schwarzenegger Gabriel Silva Brasileiro
Copyright (c) 2026 Marcele Ribeiro Valente, Lion Schwarzenegger Gabriel Silva Brasileiro, Jéssica de Sá Azevedo, André Rodrigues Pinto, Luciana Moutinho del Estal, Juan Clinton Llerena Junior https://creativecommons.org/licenses/by/4.0