Evaluation of the traditional use and commerce of medicinal plants and phythoterapics in the municipality of Resende, RJ: A contribution to the development of the National Policy on Medicinal Plants and Phythoterapics in Sul Fluminense





Medicinal Plants; Phytotherapics; National policy of medicinal plants and phytotherapics medicines.


This work aimed to carry out an ethnobotanical survey of plants commercialized as medicinal and phytotherapics in the municipality of Resende, RJ. Therefore, the main types of commerce in medicinal plants and phytotherapics were mapped and the plant species commercialized in the municipality were registered. The traditional use reported was correlated with the biological properties of metabolites biosynthesized by plant species already described in the literature. The ethnobotanical survey and research on the use of plants species and phytotherapics in the city revealed that 44% of the species described in RENISUS are sold in the open-air market and herbal stores visited, and 77% of these species are among the most consumed. It was possible to observe that many of the biological properties for which plant species are traditionally consumed are correlated with biosynthesized metabolites and evidence described in the literature. These results can help implement the National Policy on Medicinal Plants and Phytotherapics in the municipality and in Sul Fluminense, in addition to contributing to safe access, rational and sustainable use of biodiversity.


Agência Saúde. (2009). MS elabora Relação de Plantas Medicinais de Interesse ao SUS. Disponível em: http://bvsms.saude.gov.br/bvs/sus/pdf/marco/ms_relacao_plantas_medicinais_sus_0603.pdf. Acesso em 5 dez. 2021.

Ahmad, M.; Saeed, F., MehJabeen & Jahan N. (2013). Neuro-Pharmacological and analgesic effects or arnica Montana extract. International Journal of Pharmacy and Pharmaceutical Sciences, 5(4), 590-593.

Alexandre, K. P.; Yasuda, F.S.; Marques, L. C.; Gonçalves C. P.; Veiga, R. S.; Oliveira, S. M. L. & Marcucci, M. C. (2021). Guaçatonga (Casearia sylvestris SW) e porangaba (Cordia salicifolia ou Cordia ecalyculata Vell/Boraginaceae) possuem ação no emagrecimento? Brazilian Journal of Natural Sciences, 3(1), 3-15.

Almeida, M. M. B.; Ariaga, A. M. C.; Santos, A. K. L.; Lemos, T. L. G.; Braz-Filho, R. & Vieira, I. J. C. (2007). Ocorrência e atividade biológica de quassinóides da última década. Química Nova, 30(4), 1-17.

Almeida, M. R.; Lima J. A.; Santos, N. P & Pinto, A. C. (2009). Pereirina: o primeiro alcaloide isolado no Brasil? Revista Braileira de Farmacognosia, 19(4), 942-952.

Almeida, M. R.; Martinez, S. T. & Pinto, A. C. (2017). Química de Produtos Naturais: Plantas que Testemunham Histórias. Revista Virtual de Química, 9(3), 1117-1153.

Almeida, M. R.; Silva, A. E. S.; Braga, A. O.; Braga, J. M. A.; Tamaio, N. & Pinto, A. C. (2012). Anatomical description, alkaloid content and quality controlo f the bark of Pau-pereira (Geissospermum laeve, Apocynaceae). Journal of Medicinal Plants Research, 6(10), 1866-1872.

Al-Sereiti, M. R.; Abu-Amer, K. M. & Sena, P. (1999). Pharmacology of rosemary (Rosmarinus oificinalis Linn.) and its therapeutic potentials. Indian Journal of Experimental Biology, 37, 124-130.

Al Zarzour, R. A.; Ahmad, M.; Asmawi, M. Z.; Kaur, G.; Saeed, M. A. A.; AL-Mansoub, M. A.; Saghir, S. A. M.; Usman, N. S.; Al-Dulaimi, D. W. & Yam, M. F. (2017). Phyllanthus niruri standardized extract alleviates the progression of non-alcoholic fatty liver disease and decreases atherosclerotic risk in Sprague–Dawley rats. Nutrients, 9(7), 766.

Annunziata, G.; Barrea, L.; Ciampaglia, R.; Cicala, C.; Arnone, A.; Savastano, S.; Nabavi, S. M.; Tenore, G. C. & Novellino, E. (2019). Arctium lappa contributes to the management of type 2 diabetes mellitus by regulating glucose homeostasis and improving oxidative stress: a critical review of in vitro and in vivo animal: Based studies. Phytotherapy Research, 33(9), 2213-2220.

Antinarelli, L. M. R.; Pinto, N. C.; Scio, E. & Coimbra, E. S. (2015). Antileishmanial activity of some Brazilian plants, with particular reference to Casearia sylvestris. Anais da Acaemia Brasileira de Ciênias, 87(2), 733-742.

Antunes, B.F.; Otero, D. M.; Oliveira, F. M.; Jacques, A. C. & Gandra, E. A. (2020). Antioxidant and antimicrobial activity of olive trees cultivated in the Campanha Gaúcha region. Brazilian Journal of Development, 6(4), 21791-21805.

Asgarpanah, J. & Khoshkam, R. (2012). Phytochemistry and pharmacological properties of Ruta graveolens L. Journal of Medicinal Plants Research, 6(23), 3942-3949.

Athayde, A. E.; Araujo, C. E. S.; Sandjo, L. P. & Biavatti, M. W. (2021). Metabolomic analysis among ten tradicional “Arnica” (Asteraceae) from Brazil. Journal of Ethnopharmacology, 265, 113149.

Avallone, R.; Zanoli, P.; Puia, G.; Kleinschnitz, M.; Schreier, O. & Baraldi, M. (2000). Pharmacological profile of Apigenin, a flavonoid isolated from Matricaria chamomilla. Biochemical Pharmacology, 59(11),1387-1394.

Barbosa, R. J.; Silva, G. R.; Cola, I. M.; Kuchler, J. C.; Coelho, N.; Barboza, L. N.; Menetrier, J. V.; Souza, R.; Zonta, F. N.; Froehlich, D. L.; Jacomassi, E.; Soares, A. A.; Velasques, L. G.; Veiga, A. A., Souza, L. M.; Lovato, E. C. W.; Ribeiro-Paes, J. T.; Gasparotto Junior, A.; Acco, A. & Lívero, F. A. R. (2020). Promising therapeutic use of Baccharis trimera (less.) DC. as a natural hepatoprotective agent again sthepaticlesions that are caused by multiple risk factors. Journal of Ethnopharmacology, 254,112729.

Bartolome, A. P.; Villaseñor, I. M. & Yang, W. C. (2013). Bidens pilosa L. (Asteraceae): botanical properties, traditional uses, phytochemistry and pharmacology. Evidence-Based Complemenary and Alternative Medicine, 2013, 1-51.

Batiha, G. E. S.; Beshbishy, A. M.; Wasef, L.; Elewa, Y. H. A.; Abd El-Hack, M. E.; Taha, A. E.; Al-Sagheer, A. A.; Devkota, H. P. & Tufarelli, V. (2020). Uncaria tomentosa (Willd. ex Schult.) DC.: A Review on chemical constituents and biological activities. Applied Sciences, 10(8), 2668-2679.

Begmeier, D.; Berres, P. H. D.; Filippi, D.; Bilibio, D.; Bettiol, V. R. & Priamo, W. L. (2014). Extraction of total polyphenols from hibiscus (Hibiscus sabdariffa L.) and wax weed/‘sete-sangrias’ (Cuphea carthagenensis) and evaluation of their antioxidant potential. Acta Scientiarum. Technology, 36(3), 545-551.

Bektasevic, M.; Politeo, O. & Carev, I. (2021). Comparative study of chemical composition, cholinesterase inhibition and antioxidant potential of Mentha pulegium L. essential oil. Chemistry & Biodiversity, 18(3), e2000935.

Bhat, A. A.; Ahamad, B.; Rehman, U. M. & Ahmad, P. (2020). Impact of ethanolic extract of Equisetum arvense (EA1) on pancreatic carcinoma AsPC-1 cells. Saudi Journal of Biological Sciences, 27(5), 1260-1264.

Bodini, R. B.; Pugine, S. M. P.; Melo, M. P. & Carvalho, R. A. (2020). Antioxidant and anti-inflammatory properties of orally disintegrating films based on starch and hydroxypropyl methylcellulose incorporated with Cordia verbenacea (erva baleeira) extract. International Journal of Biological Macromolecules, 159, 714-724.

Boeing, T.; Moreno, K. G. T.; Gasparotto Junior, A.; Mota da Silva, L. & Souza, P. G. (2021). Phytochemistry and pharmacology of the genus Equisetum (Equisetaceae): A narrative review of the species with therapeutic potential for kidney diseases. Evidence-Based Complemenary and Alternative Medicine, 2021, 1-17.

Boeira, C. P.; Piovesan, N.; Flores, D. C. B.; Soquetta, M. B.; Lucas, B. N.; Heck, R. T.; Alves, J. S.; Campagnol, P. C. B.; Santos, D.; Flores, E. M. M.; Rosa, C. S. & Terra, N. N. (2020). Phytochemical characterization and antimicrobial activity of Cymbopogon citratus extract for application as natural antioxidant in fresh sausage. Food Chemistry, 319, 126553.

Bora, K. S. & Sharma, A. (2012). Evaluation of anxiolytic effect of Medicago sativa in mice. Pharmaceutical Biology, 50(7), 878-882.

Bora, K. S. & Sharma, A. (2011). Phytochemical and pharmacological potential of Medicago sativa: a review. Pharmaceutical Biology, 49(2), 211-220.

Borsato, M. L. C.; Grael, C. F.; Souza, G. E. & Lopes, N. P. (2000). Analgesic activity of the lignans from Lychnophora ericoides. Phytochemistry, 55(7), 809-813.

Brasil. (2021). Parque Estadual do Itatiaia. Ministério do Meio Ambiente. ICMBio, 2021. Disponível em: http://www.icmbio.gov.br/parnaitatiaia/. Acesso em 5 dez. 2021.

Brasil. (2006a). Política Nacional de Plantas Medicinais e Fitoterápicos. Brasilia: Ministério da Saúde.

Brasil. (2006b). Decreto nº 5.813, de 22 de junho de 2006. Ministério da Saúde; 2006. Disponível em: http://www.planalto.gov.br/ccivil_03/_ato2004-2006/2006/decreto/d5813.htm.

Brasil. (2006c). Portaria nº 971, de 3 de maio de 2006. Ministério da Saúde; 2006. Disponível em: https://bvsms.saude.gov.br/bvs/saudelegis/gm/2006/prt0971_03_05_2006.html.

Brasil. (2006d). Política de Práticas Integrativas e Complementares no SUS – PNPIC-SUS. Brasilia: Ministério da Saúde.

Brasil. (2008). Portaria Interministerial nº 2960, de 9 de dezembro de 2008. Ministério da Saúde; 2008. Disponível em: https://bvsms.saude.gov.br/bvs/saudelegis/gm/2008/pri2960_09_12_2008.html.

Brasil. (2009). Programa Nacional de Plantas Medicinais e Fitoterápicos. Brasilia: Ministério da Saúde.

Brasil. (2010). Resolução RDC No. 14, de 31 de março de 2010. Ministério da Saúde. Agência Nacional de Vigilância Sanitária; 2010. Disponível em: https://bvsms.saude.gov.br/bvs/saudelegis/anvisa/2010/rdc0014_31_03_2010.html.

Brasil. (2012). Portaria nº 533, de 28 de março de 2012. Ministério da Saúde; 2012. Disponível em: https://bvsms.saude.gov.br/bvs/saudelegis/gm/2012/prt0533_28_03_2012.html.

Brasil. (2013a). Relação Nacional de Medicamentos Essenciais: RENAME 2013. Brasilia: Ministério da Saúde.

Brasil. (2013b). Resolução RDC No. 14, de 14 de março de 2013. Ministério da Saúde, Agência Nacional de Vigilância Sanitária; 2013. Disponível em: https://bvsms.saude.gov.br/bvs/saudelegis/anvisa/2013/rdc0014_14_03_2013.pdf.

Brasil. (2014). Resolução RDC no. 26, de 13 de maio de 2014. Ministério da Saúde, Agência Nacional de Vigilância Sanitária; 2014. Disponível em: https://bvsms.saude.gov.br/bvs/saudelegis/anvisa/2014/rdc0026_13_05_2014.pdf.

Brasil. (2016). Uso de fitoterápicos e plantas medicinais cresce no SUS. Ministério da Saúde. Disponível em: https://www.saude.gov.br/noticias/agencia-saude/24205-uso-de-fitoterapicos-e-plantas-medicinais-cresce-no-sus. Acesso em 5 dez. 2021.

Brasil. (2018). Consolidado de normas de registro e notificações de fitoterápicos. Brasília: Agência Nacional de Vigilância Sanitária.

Brasil. (2021). Formulário de Fitoterápicos. Farmacopéia Brasileira. Brasília: Agência Nacional de Vigilância Sanitária.

Budiman, A.; Praditasari, A.; Rahayu, D. & Aulifa D. (2019). Formulation of antioxidant gel from black mulberry fruit extract (Morus nigra L.). Journal of Pharmacy and Bioallied Sciences, 11(3), 216-22.

Bueno, G.; Rico, S. L. C.; Périco, L. L.; Ohara, R.; Rodrigues, V. P.; Emílio-Silva, M. T.; Assunção, R.; Machado da Rocha, L. R.; Nunes, D. S.; Besten, M. A.; Heiden, G.; Lima Camargo, A. C.; Justulin, L. A. & Hiruma-Lima, C. A. (2021). The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity. Journal of Ethnopharmacology, 271, 113832-41.

Carvalho, C. A.; Lourenço, M. V.; Bertoni, B. W.; França, S. C.; Pereira, P. S.; Fachin, A. L. & Pereira, A. M. S. (2009). Atividade antioxidante de Jacaranda decurrens Cham., Bignoniaceae. Revista Brasileira de Farmacognosia, 19(2B), 592-598.

Cefali, L. C.; Ataide, J. A.; Fernandes, A. R.; Sanchez-Lopez, E.; Sousa, I. M. O.; Figueiredo, M. C.; Ruiz, A. L. T. G.; Foglio, M. A.; Mazzola, P. G. & Souto, E. B. (2019). Evaluation of in vitro solar protection factor (SPF), antioxidant activity, and cell viability of mixed vegetable extracts from Dirmophandra mollis Benth, Ginkgo biloba L., Ruta graveolens L., and Vitis vinífera L. Plants, 8(11), 453.

Chouksey, D.; Upmanyu, N. & Pawar, R. S. (2013). Central nervous system activity of Illicium verum fruit extracts. Asian Pacific Journal of Tropical Medicine, 6(11), 869-875.

CNCFlora. Lychnophora pinaster. Lista Vermelha da flora brasileira versão 2012.2 Centro Nacional de Conservação da Flora. Disponível em: http://cncflora.jbrj.gov.br/portal/pt-br/profile/Lychnophora pinaster. Acesso em 5 dez. 2021.

Cruces, I. L.; Patelli, T. H. C.; Tashima, C. M. & Mello-Peixoto, E. C. T. (2013). Plantas medicinais no controle de urolitíase. Revista Brasileira de Plantas Medicinais, 15(4, suppl 1), 780-788.

Cui, J.; Zeng, S. & Zhang, C. (2022). Anti‐hyperglycemic effects of Burdock (Arctium lappa L.) leaf flavonoids through inhibiting α‐amylase and α‐glucosidase. International Journal of Food Science & Technology, 57(1), 541-551.

Das, S. (2020). Natural therapeutics for urinary tract infections—a review. Future Journal of Pharmaceutical Sciences, 6(1), 64.

Daisy, P.; Rayan N. A. & Rajathi, D. (2007). Hypoglycemic and other related effects of Elephantopus scaber extracts on alloxan induced diabetic rats. Journal of Biological Sciences, 7(2), 433-437.

Dias, M. M.; Zuza, O.; Riani, L. R.; Faria Pinto, P.; Pinto, P. L. S.; Silva, M. P.; Moraes, J.; Ataíde, A. C. Z.; Oliveira Silva, F.; Cecilio, A. B. & Silva Filho, A. A. (2017). In vitro schistosomicidal and antiviral activities of Arctium lappa L. (Asteraceae) against Schistosoma mansoni and Herpes simplex virus-1. Biomedicine & Pharmacotherapy, 94, 489-498.

Elango, C. & Devaraj, S. N. (2010). Immunomodulatory effect of Hawthorn extract in an experimental stroke model. Journal of Neuroinflammation, 7(1), 97.

Elekofehinti, O. O.; Onunkun, A. T. & Olaleye T. M. (2020). Cymbopogon citratus (DC.) Stapf mitigates ER-stress induced by streptozotocin in rats via down-regulation of GRP78 and up-regulation of Nrf2 signaling. Journal of Ethnopharmacology, 262, 113130.

El-Ghorab, A.; El-Massry, K. F. & Shibamoto, T. (2007). Chemical composition of the volatile extract and antioxidant activities of the volatile and nonvolatile extracts of Egyptian Corn Silk (Zea mays L.). Journal of Agricultural and Food Chemistry, 55(22), 9124–9127.

Erkan, N.; Ayaranci, G. & Ayaranci, E. (2008). Antioxidant activities of rosemary (Rosmarinus officinalis L.) extract, blackseed (Nigella sativa L.) essential oil, carnosic acid, rosmarinic acid and sesamol. Food Chemistry, 110(1), 76-82.

Farid, A.; Kamel, D.; Abdelwahab Montaser, S.; Mohamed Ahmed, M.; El Amir, M. & El Amir, A. (2020). Synergetic role of senna and fennel extracts as antioxidant, anti-inflammatory and anti-mutagenic agents in irradiated human blood lymphocyte cultures. Journal of Radiation Research and Applied Sciences, 13(1), 191-199.

Feriani, A.; Tir, M.; Hamed, M.; Sila, A.; Nahdi, S.; Alwasel, S.; Harrath, A. H. & Tlili, N. (2020). Multidirectional insights on polysaccharides from Schinus terebinthifolius and Schinus molle fruits: physicochemical and functional profiles, in vitro antioxidant, anti-genotoxicity, antidiabetic, and antihemolytic capacities, and in vivo anti-inflammatory and anti-nociceptive properties. International Journal of Biological Macromolecules, 165(Pt B), 2576-2587.

Fernández, J.; Lagos, P.; Riviera, P. & Zamorano-Ponce, E. (2009). Effect of boldo (Peumus boldus Molina) infusion on lipoperoxidation induced by cisplatin in mice liver. Phytotherapy Research, 23(7), 1024-1027.

Ferrante, C.; Chiavaroli, A.; Angelini, P.; Venanzoni, R.; Flores, G. A.; Brunetti, L.; Petrucci, M.; Politi, M.; Menghini, L., Leone, S.; Recinella, L.; Gokhan, Z.; Ak, G.; Mascio, M.; Bacchin, F. & Orlando, G. (2020). Phenolic content and antimicrobial and anti-inflammatory effects of Solidago virga-aurea, Phyllanthus niruri, Epilobium angustifolium, Peumus boldus, and Ononis spinosa Extracts. Antibiotics, 9(11), 783-804.

Ferreira, S. A.; Guimarães, A. G.; Ferrari, F. C.; Carneiro, C. M.; Paiva, N. C. N. & Guimarães, D. A. S. (2014). Assessment of acute toxicity of the ethanolic extract of Lychnophora pinaster (Brazilian arnica). Revista Brasileira de Farmacognosia, 24(5), 553-560.

Ghowsi, M.; Yousofvand, N. & Moradi S. (2020). Effects of Salvia officinalis L. (common sage) leaves tea on insulin resistance, lipid profile, andoxidative stress in rats with polycysticovary: An experimental study. Avicenna Journal of Phytomedicine, 10(3), 263-272.

Gonçalves, N. M. T.; Gerenutti, M.; Chaves, D. S. A. & Vila, M. M. D. C. (2011). A tradição popular como ferramenta para a implantação da Fitoterapia no município de Volta Redonda, RJ. Revista Brasileira de Farmacognosia, 92(4), 346-351.

Google Mapas (2022). Município de Resende, RJ. Disponível em: https://www.google.com.br/maps/place/Resende,+RJ/@-22.4648432,-44.4811504,7747m/data=!3m1!1e3!4m5!3m4!1s0x9e778dd541f595:0x3823b6f49a15df81!8m2!3d-22.4722561!4d-44.4649211. Acesso em 17 jan. 2022.

Hacke, A. C. M.; Miyoshi, E.; Marques, J. A. & Pereira, R. P. (2020). Anxiolytic properties of Cymbopogon citratus (DC.) stapf extract, essential oil and its constituents in zebrafish (Danio rerio). Journal of Ethnopharmacology, 260, 113036.

Hacke, A. C. M.; Miyoshi, E.; Marques, J. A. & Pereira, R. P. (2021). Cymbopogon citratus (DC.) Stapf, citral and geraniol exhibit anticonvulsant and neuroprotective effects in pentylenetetrazole-induced seizures in zebrafish. Journal of Ethnopharmacology, 275, 114142.

Hajhashemi, V.; Ghannadi, A. & Sharif, B. (2003). Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of Lavandula angustifolia Mill. Journal of Ethnopharmacology, 89(1), 67-71.

Han, Y.; Li, X.; Zhang, X.; Gao, Y.; Qi, R.; Cai, R. & Qi, Y. (2020). Isodeoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber Linn., inhibits pro-inflammatory mediators’ production through both NF-κB and AP-1 pathways in LPS-activated macrophages. Internacional Immunopharmacology, 84, 106528.

Heymanns, A. C.; Albano, M. N.; Silveira, M. R.; Muller, S. D.; Petronilho, F. C.; Gainski, L. D.; Cargnin-Ferreira, E. & Piovezan, A. P. (2021). Macroscopic, biochemical and hystological evaluation of topical anti-inflammatory activity of Casearia sylvestris (Flacourtiaceae) in mice. Journal of Ethnopharmacology, 264, 113139.

Hui, L.; He, L.; Huan, L.; Lan, L. X. & AiGuo, Z. (2010). Chemical composition of lavender essential oil and its antioxidant activity and inhibition against rhinitis related bacteria. African Journal of Microbiology Research, 4(4), 309-313.

Iannitti, T.; Morales-Medina, J. C.; Bellavite, P.; Rottigni, V. & Palmieri, B. (2016). Effectiveness and safety of Arnica montana in post-surgical setting, pain and inflammation. American Journal of Therapeutics, 23(1), e184-e197.

Instituto Brasileiro de Geografia e Estatística - IBGE, 2017. Cidades - Resende. Disponível em: https://cidades.ibge.gov.br/brasil/rj/resende/panorama. Acesso em 5 dez. 2021.

Instituto Nacional do Ambiente – INEA. Parque Estadual da Pedra Selada. Disponível em: http://www.inea.rj.gov.br/Portal/Agendas/BIODIVERSIDADEEAREASPROTEGIDAS/UnidadesdeConservacao/INEA_008422. Acesso em 5 dez. 2021.

Iwamoto, L. H.; Vendramini-Costa, D. B.; Monteiro, P. A.; Ruiz, A. L. T. G.; Sousa, I. M. O.; Foglio, M. A.; Carvalho, J. E. & Rodrigues, R. A. F. K. (2015). Anticancer and Anti-Inflammatory Activities of a Standardized Dichloromethane Extract from Piper umbellatum L. Leaves. Evidence-Based Complemenary and Alternative Medicine, 2015.

Jan, N.; Andrabi, K.I. & John, R. (2017). Calendula Officinalis - An important medicinal plant with potential biological properties. Proceedings of the Indian National Science Academy, 83(4),769-787.

Keefea, J. R.; Mao, J. J.; Soeller, I.; Li, Q. S. & Amsterdam, J. D. (2016). Short-term open-label chamomile (Matricaria chamomilla L.) therapy of moderate to severe generalized anxiety disorder. Phytomedicine, 23(14), 1699–1705.

Khazaei, H.; Pesce, M.; Patruno, A.; Aneva, I. Y. & Farzaei, M. H. (2020). Medicinal plants for diabetes associated neurodegenerative diseases: a systematic review of preclinical studies. Phytotherapy Research, 35(4), 1697-1718.

Knipping, K.; Esch, E. C. A. M.; Wijering, S. C.; Heide, S.; Dubois, A. E. & Garssen, J. (2008). In vitro and in vivo anti-allergic effects of Arctium lappa L. Experimental Biology and Medicine, 233(11),1469-1477.

Koubaa, F. G.; Chaâbane, M.; Choura, B.; Turki, M.; Makni-Ayadi, F. & El Feki, A. (2020). Hepatoprotective effects of Taraxacum officinale root extract on permethrin-induced liver toxicity in adult mice. Pharmaceutical and Biomedical Reserach, 6(3), 223-236.

Kreis, W.; Munkert, J. & Pádua R. M. (2017). Biossíntese de metabólitos primários e secundários. In Simões, C. M. O.; Schenkel, E. P.; Mello, J. C. P.; Petrovick, P. R. (Orgs.), Farmacognosia do produto natural ao medicamento (pp. 147-166). Porto Alegre: Artmed Editora.

Li, L.; Wei, S.; Zhu, T.; Xue, G.; Xu, D.; Wang, W.; Wang, X.; Luo, J. & Kong, L. (2019). Anti-inflammatory norabietane diterpenoids from the leaves of Salvia officinalis L. Journal of Functional Foods, 54, 154-163.

Lima, J. A.; Costa, T. W. R.; Silva, L. L.; Miranda, A. L. P. & Pinto, A. C. (2016). Antinociceptive and anti-inflammatory effects of a Geissospermum vellosii stem bark fraction. Anais da Academia Brasileira de Ciências, 88(1), 237-248.

Lima, L. F.; Oliveira, J. O.; Carneiro, J. N. P.; Lima, C. N. F.; Coutinho, H. D. M. & Morais-Braga, M. F. B. (2021). Ethnobotanical and antimicrobial activities of the Gossypium (Cotton) genus: a review. Journal of Ethnopharmacology, 279, 114363.

Lima, T. C.; Matos, S. S.; Carvalho, T. F.; Silveira-Filho, A. J.; Couto, L. P. S. M.; Quintans-Júnior, L. J.; Quintas, J. S. S.; Silva, A. M. O.; Heimfarth, L.; Passos, F. R. S.; Gandhi, S. R.; Lima, B. S. & Silva, F. A. (2020). Evidence for the involvement of IL-1β and TNF-α in anti-inflammatory effect and antioxidative stress profile of the standardized dried extract from Miconia albicans Sw. (Triana) Leaves (Melastomataceae). Journal of Ethnopharmacology, 259, 112908.

Lima, T. C. D.; Cardoso, M. V.; Modesto, T.; Oliveira, A. L. B.; Silva, M. N. & Monteiro, M. C. (2016). Breve revisão etnobotânica, fitoquímica e farmacologia de Stryphnodendron adstringens utilizada na Amazônia. Revista Fitos, 10(3), 329-338.

Lorençone, B. R.; Guarnier, L. P.; Palozi, R. A. C.; Romão, P. V. M.; Marques, A. A. M.; Klider, L. M.; Souza, R. I. C.; Santos, A. C.; Tirloni, C. A. S.; Cassemiro, N. S.; Silva, D. B.; Budel, J. M. & Junior, A. G. (2021). Atheroprotective properties of Costus spicatus (Jacq.) Sw. in Female Rats. Life, 11(3), 212-233.

Maghsoumi-Norouzabad, L.; Alipoor, B.; Abed, R.; Efteknar Sadat, B.; Mesgari-Abbasi, M. & Asghari Jafarabadi, M. (2016). Effects of Arctium lappa L. (Burdock) root tea on inflammatory status and oxidative stress in patients with knee osteoarthritis. International Journal of Rheumatic Diseases, 19(3), 255-261.

Malfa, G. A.; Di Giacomo, C.; Cardia, L.; Sorbara, E. E.; Mannucci, C. & Calapai, G. (2021). A standardized extract of Opuntia ficus‐indica (L.) Mill and Olea europaea L. improves gastrointestinal discomfort: a double-blinded randomized-controlled study. Phytotherapy Research, 35(7), 3756-3768.

Martinazzo, A. P.; Filho, L. C. C.; Rosa, D. A.; Teodoro, C. E. S. & Tomazelli, K. K. (2013). Perfil de utilização de Fitoterápicos nos municípios de volta Redonda e Barra Mansa/RJ. Revista Fitos, 8(2), 103-112.

Matsubara, S. & Rodriguez-Amaya, D. B. (2006). Teores de catequinas e teaflavinas em chás comercializados no Brasil. Ciência e Tecnologia de Alimentos, 26(2), 401-407.

Melo, C. P. B.; Saito, P.; Vale, D. L.; Rodrigues, C. C. A.; Pinto, I. C.; Martinez, R. M.; Bezerra, J. R.; Baracat, M. M.; Verri, W. A.; Fonseca-Bazzo, Y. M.; Georgetti, S. R. & Casagrande, R. (2021). Protective effect of oral treatment with Cordia verbenacea extract against UVB irradiation deleterious effects in the skin of hairless mouse. Journal of Photochemistry Photobiology B: Biology, 216, 112151.

Mondin, C. A. (2020). Sphagneticola trilobata (L.) Pruski. Flora do Brasil 2020. Jardim Botânico do Rio de Janeiro. Disponível em: http://floradobrasil.jbrj.gov.br/reflora/floradobrasil/FB16304. Acesso em 17 jan. 2022.

Moreno, K. G. T.; Junior, A. G.; Santos, A. C.; Palozi, R. A. C.; Guarnier, L. P.; Marques, A. A. M.; Romão, P. V. M.; Lorençone, B. R.; Cassemiro, N. S.; Silva, D. B.; Tirloni, C. A. S. & Barros, M. E. (2021). Nephroprotective and antilithiatic activities of Costus spicatus (Jacq.) Sw.: Ethnopharmacological investigation of a species from the Dourados region, Mato Grosso do Sul state, Brazil. Journal of Ethnopharmacology, 266, 113409.

Nascimento, C. A.; Santos, A. C. M.; Silva, D. M.; Barbosa, N. R.; Moura, E. L.; Balliano, T. L.; Figueiredo, E. V. M. S.; Farias, K. F. & Pitta, G. B. B.(2021). Evidências sobre as propriedades do extrato de Stryphnodendron adstringens (Mart.) Coville (Barbatimão) para a prática clínica. Research, Society and Development, 10(1), e3010111350.

Nascimento, E. L.; Watanabe, M.; Fonseca, C. D.; Schlottfeldt, F. S. & Vattimo, M. F. F. (2014). Renoprotective effect of the Echinodorus macrophyllus in induced renal injury. Acta Paulista de Enfermagem, 27(1), 12-17.

Neto, J. N.; Coelho, T. M.; Aguiar, G. C.; Carvalho, L. R.; Araújo, A. G. P.; Girão, M. J. B. C. & Schor, E. (2011). Experimental endometriosis reduction in rats treated with Uncaria tomentosa (cat’s claw) extract. European Journal of Obstetrics & Gynecology and Reproductive Biology, 154(2), 205–208.

Noriega, P.; Ropke, C. D.; Consiglieri, V. O.; Taqueda, M. E. S.; Tavares, L. C.; Wasicky, A.; Bacchi, E. M. & Barros, S. B. M. (2008). Optimization of Pothomorphe umbellata (L.) Miquel topical formulations using experimental design. International Journal of Pharmaceutics, 353(1), 149-159.

Oliveira, I. S. S.; Colares, A. V.; Cardoso, F. O.; Tellis, C. J. M.; Chagas, M, S. S.; Behrens, M. D.; Calabrese, K. S.; Almeida-Souza, F. & Abreu-Silva, A. L. (2019). Vernonia polysphaera Baker: anti-inflammatory activity in vivo and inhibitory effect in lps-stimulated raw 264.7 cells. Plos One, 14(12), e0225275.

Oliveira, R. T.; Rolim, C. S. S.; Rolim, L. N.; Sousa, M. L. G.; Martins, G. A. S.; Castro, L. M.; Nascimento, W. M.; Saraiva-Bonatto, E. C.; Numonura, R. C. S.; Lamarão, C. V. & Zanotto, S. P. (2021). Endopleura uchi – A review about its nutritional compounds, biological activities and production market. Food Research International, 139, 109884.

Oliveira, V. M.; Thomaz, D. V.; Baldoni, F. M. D. C. & Couto, R. O. (2021). Is the systemic administration of arnica extracts safe? A systematic review of preclinical trials. Research, Society and Development, 10(8), e27110817257.

Otenio, J. C.; Baisch, R. G.; Carneiro, V. P. P.; Lourenço, E. L. B.; Alberton, O. & Jacomassi, E. (2020). Etnofarmacologia da Cuphea carthagenesis (Jacq.) J. F. Macbr: Uma revisão. Brazilian Journal of Development, 6(3), 10206-10219.

Otero, C.; Miranda-Rojas, S.; Llancalahuén, F. M.; Fuentes, J. A.; Atala, C.; González-Silva, G.; Verdugo, D.; Sierra-Rosales, P.; Moreno, A. & Gordilho-Fuenzalida, F. (2022). Biochemical characterization of Peumus boldus fruits: insights of its antioxidant properties through a theoretical approach. Food Chemistry, 370, 131012.

Owlia, P.; Rasooli, I. & Saderi, H. (2007). Antistreptococcal and antioxidant activity of essential oil from Matricaria chamomilla L. Research Journal of Biological Sciences, 2(2), 155-160.

Owoyele, B. V.; Negedu, M. N.; Olaniran, S. O.; Onasanwo, S. A.; Sanya, J. O.; Oyeleke, S. A.; Lbidapo, A. J. & Soladoye, A. O. (2010). Analgesic and anti-inflammatory effects of aqueous extract of Zea mays husk in male Wistar rats. Journal of Medicinal Food., 13(2), 343-347.

Parente, C. E. T. & Rosa, M. M. T. (2001). Plantas comercializadas como medicinais no Município de Barra do Piraí, RJ. Rodriguésia, 52(80), 47-59.

Parente, L. M. L.; Lino Junior, R. S.; Tresvenzol, L. M. F.; Vinaud, M. C.; Paula, J. R. & Paulo, N. M. (2012). Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil. Evidence-Based Complemenary and Alternative Medicine, 2012, 375671.

Pascoalino, S. D.; Lüdtke, D. D.; Heymanns, A. C.; Salm, D.; Costa, D. M.; Martins, D. F.; Horewicz, V. V.; Bobinski, F. & Piovezan, A. P. (2020). Antihyperalgesic effect of exercise is augmented by the oral pretreatment with extract of Casearia sylvestris in an animal model of osteoarthritis. Journal of Orthopaedics, Trauma and Rehabilitation, 27(2), 148-156.

Patra, J. K.; Das, G.; Bose, S.; Banerjee, S.; Vishnuprassad, C. N.; Pilar, R. M. & Shin, H. (2020). Star anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance. Phytotherapy Research, 34(6), 1248-1267.

Pereira, O. R.; Catarino, M. D.; Afonso, A. F.; Silva, A. M. S. & Cardoso, S. M. (2018). Salvia elegans, Salvia greggii and Salvia officinalis decoctions: Antioxidant activities and inhibition of carbohydrate and lipid metabolic enzymes. Molecules, 23(12), 3169.

Pimentel, A. S. G. (2021). Rosmarinus Officinalis L. para o tratamento da ansiedade: uma revisão de literatura. Research, Society and Development, 10(11), e285101119635.

Pinheiro, A. C. S.; Pais, A. A.; Tardivo, A. C. B. & Alves, M. J. Q. F. (2011). Efeito do extrato aquoso de cabelo de milho (Zea mays L.) sobre a excreção renal de água e eletrólitos e pressão arterial em ratos Wistar anestesiados. Revista Brasileira de Plantas Medicinais, 13(4), 375-381.

Portella, V. G.; Conseza, G. P.; Diniz, L. R. L.; Pacheco, L. F.; Cassali, G. D.; Caliari, M. V.; Brandão, M. G. L. & Vieira, M. A. R. (2012). Nephroprotective effect of Echinodorus macrophyllus Micheli on gentamicin-induced nephrotoxicity in rats. Nephron Extra, 2(1), 177-183.

Quezada, N.; Asensio, M.; Del Valle, J. M.; Aguilera, J. M. & Gómez, B. (2006). Antioxidant activity of crude extract, alkaloid fraction, and flavonoid fraction from Boldo (Peumus boldus Molina) leaves. Journal of Food Science, 69(5), 371-376.

Quintans-Junior, L. J.; Gandhi, S. R.; Passos, F. R. S.; Heimfarth, L.; Pereira, E. W. M.; Monteiro, B. S.; Santos, K. S.; Duarte, M. C.; Abreu, L. S.; Nascimento, Y. M.; Tavares, J. F.; Silva, M. S.; Menezes, I. R. A.; Coutinho, H. D. M.; Lima, A. A. N.; Zengin, G. & Quintans, J. S. S. (2020). Dereplication and quantification of the ethanol extract of Miconia albicans (Melastomaceae) by HPLC-DAD-ESI-/MS/MS, and assessment of its anti-hyperalgesic and anti-inflammatory profiles in a micearthritis-like model: evidence for involvement of TNF-α, IL-1β and IL-6. Journal of Ethnopharmacology, 258, 112938.

Rahimi, H. M.; Khosravi, M.; Hesari, Z.; Sharifdini, M.; Mirjalali, H. & Zali, M. R. (2020). Anti‐toxoplasma activity and chemical compositions of aquatic extract of Mentha pulegium L. and Rubus idaeus L.: an in vitro study. Food Science & Nutrition, 8(7), 3656-3664.

Raji, Y. & Oloyede, G. K. (2012). Antiulcerogenic effects and possible mechanism of action of Quassia amara (L. Simaroubaceae) extract and its bioactive principle in rats. African Journal of Traditional, Complementary and Alternative Medicines, 9(1), 112‐119.

Rambo, D. F.; Biegelmeyer, R.; Toson, N. S. B.; Dresch, R. R.; Moreno, P. R. H. & Henriques, A. T. (2019a). Box–Behnken experimental design for extraction optimization of alkaloids from Erythrina verna Vell. Trunk barks and LC method validation. Industrial Crops and Products, 133, 250-258.

Rambo, D. F.; Biegelmeyer, R.; Toson, N. S. B.; Dresch, R. R.; Moreno, P. R. H. & Henriques, A. T. (2019b). The genus Erythrina L.: a review on its alkaloids, preclinical, and clinical studies. Phytotherapy Research, 33(5), 1258-1276.

Rana, M. G.; Katbamna, R. V.; Padhya, A. A.; Dudhrejiya, A. D.; Jivani, N. P. & Sheth, N. R. (2010). In vitro antioxidant and free radical scavenging studies of alcoholic extract of Medicago sativa L. Romanian Journal of Biology – Plant Biology, 55(1), 15-22.

RENISUS. (2009). Relação Nacional de Plantas Medicinais de Interesse ao SUS. Ministério da Saúde. Disponível em: http://portal.saude.gov.br/portal/arquivos/pdf/RENISUS.pdf. Acesso em 5 dez. 2021.

Revilla, J. (2002). Plantas da Amazônia - Oportunidades Econômicas e Sustentáveis; Manaus: INPA.

Roby, M. H. H.; Sharhan, M. A.; Selim, K. A. H. & Khalel, I. K. (2013). Antioxidant and antimicrobial activities of essential oil and extracts of fennel (Foeniculum vulgare L.) and chamomile (Matricaria chamomilla L.). Industrial Crops and Products, 44, 437-445.

Rodrigues, E. L.; Marcelino, G.; Silva, G. T.; Figueiredo, P. S.; Garcez, W. S.; Corsino, J.; Guimarães, R. C. A. & Freitas, K. C. (2019). Nutraceutical and medicinal potential of the Morus species in metabolic dysfunctions. International Journal of Molecular Sciences, 20(2), 301.

Rodrigues, S. O.; Vieira, A. L. S. M.; Barros, N. B. & Oliveira, C. A. B. (2021). Phytotherapy as an alternative in the treatment of menopause symptoms. Brazilian Journal of Development., 7(4), 38529-38542.

Saeed, M.; Naveed, M.; Arif, M.; Kakar, M. U.; Manzoor, R.; Abd EL-Hack, M. E.; Alagawany, M.; Tiwari, R.; Khandia, R.; Munjal, A.; Karthik, K.; Dhama, K.; Iqbal, H. M. N.; Dadar, M. & Sun, C. (2017). Green tea (Camellia sinensis) and l-theanine: medicinal values and beneficial applications in humans: Acomprehensive review. Biomedicine & Pharmacotherapy, 95, 1260-1275.

Santana, L. C. L. R.; Brito, M. R. M.; Oliveira, G. L. S.; Citó, A. M. G. L.; Alves, C. Q.; David, J. M. & Freitas, R. M. (2014). Mikania glomerata: Phytochemical, pharmacological, and neurochemical study. Evidence-Based Complemenary and Alternative Medicine, 2014, 710410.

Santos, A. R. F. C.; Cruz, J. H. A.; Guênes, G. M. T.; Oliveira Filho, A. A. & Alves, M. A. S. G. (2019). Matricaria chamomilla L: propriedades farmacológicas. Archives of Health Investigation, 8(12), 846-852.

Santos, M. C.; Toson, N. S. B.; Pimentel, M. C. B.; Bordignon, S. A. L.; Mendez, A. S. L. & Henriques, A. T. (2020). Polyphenols composition from leaves of Cuphea spp. and inhibitor potential, in vitro, of angiotensin I-converting enzyme (ACE). Journal of Ethnopharmacology, 255, 112781.

Santos-Oliveira, R.; Coulaud-Cunha, S. & Colaço W. (2009). Revisão da Maytenus ilicifolia Mart. ex Reissek, Celastraceae. Contribuição ao estudo das propriedades farmacológicas. Revista Brasileira de Farmacognosia, 19(2b), 650-659.

Santos, R. I. (2004). Metabolsimo primário e origem de metabólitos secundários. In Simões, C. M. O.; Schenkel, E. P.; Gosmann, G.; Mello, J. C. P.; Mentz, L. A.; Petrovick, P. R. (Orgs.) Farmacognosia da planta ao medicamento. (pp. 403-434) Porto Alegre/Florianópolis: Editora da UFRGS/ Editora da UFSC.

Savych, A.; Bilyk, O.; Vaschuk, V. & Humeniuk, L. (2021). Analysis of inulin and fructans in Taraxacum officinale L. roots the main inulin-containing component of antidiabetic herbal mixture. Pharmacia, 68(3), 527-532.

Schaedler, M. I.; Palozi, R. A. C.; Tirloni, C. A. S.; Silva, A. O.; Araújo, V. O.; Lourenço, E. L. B.; Souza, L. M.; Lívero, F. A. R. & Gasparotto Junior, A. (2018). Redox regulation and NO/cGMP plus K+ channel activation contributes to cardiorenal protection induced by Cuphea carthagenensis (Jacq.) J.F. Macbr. in ovariectomized hypertensive rats. Phytomedicine, 51, 7–19.

Schindler, M. S. Z.; Calisto, J. F. F.; Marins, K.; Regginato, A.; Mezzomo, H.; Zanatta, A. P.; Radunz, A. L.; Mariot, M. P.; Dal Magro, J. & Zanatta, L. (2021). Characterization of the chemical profile and the effects of ethanolic extracts of Maytenus ilicifolia Mart. ex Reissek on glucose metabolism in normal hyperglycemic rats. Journal of Ethnopharmacology, 276, 114173.

Senger, A. E. V.; Schwanke, C. H. A. & Gottlieb, M. G. V. (2010). Chá verde (Camellia sinensis) e suas propriedades funcionais nas doenças crônicas não transmissíveis. Scientia Medica, 20(4), 292-300.

Serra, M. B.; Barroso, W. A.; Rocha, C.; Furtado, P. G. R.; Borges, A. C. R.; Silva, S. N.; Tangerina, M. M. P.; Nascimento, J. R.; Vilegas, W.; Alves, A. C.; Barbeiro, D. F.; Souza, H. P.; Abreu, I. C.; Brges, M. O. R. & Gonçalves, R. V. (2020). Chemical characterization and wound healing property of Jacaranda decurrens Cham. (Bignoniaceae): an experimental study based on molecular mechanisms. Evidence-Based Complemenary and Alternative Medicine, 2020, 4749712.

Seyedjavadi, S. S.; Khani, S.; Zare-Zardini, H.; Halabian, R.; Goudarzi, M.; Khatami, S.; Fooladi, I. A. A.; Amani, J. & Razzaghi-Abyaneh, M. (2019). Isolation, functional characterization, and biological properties of MCh- AMP1, a novel antifungal peptide from Matricaria chamomilla L. Chemical Biology & Drug Design, 93(5), 949-959.

Sheikhani, A.; Kholdi, N. & Mokhtari, M. (2017). An overview of the most effective tranquilizer herbs. Journal of Basic and Clinical Pathophysiology, 5(2), 27-34.

Shen, X.; Guo, M.; Yu, H.; Liu, D.; Lu, Z. & Lu, Y. (2019). Propionibacterium acnes related anti-inflammation and skin hydration activities of madecassoside, a pentacyclic triterpene saponin from Centella asiatica. Bioscience, Biotechnology, and Biochemistry, 83(3), 561-568.

Silva, A. M.; Paes, L. W. C.; Martinazzo, A. P.; Souza, P. P. & Martins, F. A. C. B. (2021). Plantas medicinais como recurso terapêutico nos bairros Siderópolis e Santa Rita do Zarur em Volta Redonda/RJ. Brazilian Journal of Development, 7(2), 11997-12014.

Silva, C. J.; Bastos, J. K. & Takahashi, C. S. (2010). Evaluation of the genotoxic and cytotoxic effects of crude extracts of Cordia ecalyculata and Echinodorus grandiflorus. Journal of Ethnopharmacology, 127(2), 445–450.

Silva, G. P.; Fernandes, D. C.; Vigliano, M. V.; Fonseca, E. N.; Santos, S. V. M.; Marques, P. V.; Justo, M. G.; Sabino, K. C. C. & Coelho, M. G. P. (2016). Flavonoid-enriched fraction from Echinodorus macrophyllus aqueous extract exhibits high in-vitro and in-vivo anti-inflammatory activity. Journal of Pharmacy and Pharmacology, 68(12), 1584-1596.

Silva-López, R. E. & Santos, B. C. (2015). Bauhinia forficata Link (Fabaceae). Revista Fitos, 9(3), 217-232.

Silva, M. V. S.; Padilha, R. T. & Padilha, D. M. M. (2021). Benefícios da Moringa oleifera para saúde humana e animal: Revisão de Literatura. Research, Society and Development., 10(8), e50010817495.

Soheili, M. & Salami, M. (2019). Lavandula angustifolia biological characteristics: an in vitro study. Journal of Cellular Physiology, 234(9), 16424-16430.

Sombra, A. C. (2016). Arranjo Produtivo Local - Volta Redonda, uma abordagem regional sobre os aspectos etnobotânicos, agroecológicos e serviços relacionados à Fitoterapia. Revista Fitos, 10(4), 14-20.

Spósito, L.; Oda, F. B.; Vieira, J. H.; Carvalho, F. A.; Ramos, M. A. S.; Castro, R. C.; Crevelin, E. J.; Crotti, A. E. M.; Santos, A. G.; Silva, P. B.; Chorilli, M. & Bauab, T. M. (2019). In vitro and in vivo anti-Helicobacter pylori activity of Casearia sylvestris leaf derivatives. Journal of Ethnopharmacology, 233, 1-12.

Swapna, K.; Uddandrao, V. V. S.; Parim, B.; Ravindarnaik, R.; Suresh, P.; Ponnusamy, P.; Balakrishnan, S.; Vadivukkarasi, S.; Harishankar, N.; Reddy, K. P.; Nivedla, P. R. & Saravanan, G. (2019). Effects of asiatic acid, an active constituent in Centella asiatica (L.): restorative perspectives of streptozotocin-nicotinamide induced changes on lipid profile and lipid metabolic enzymes in diabetic rats. Comparative Clinical Pathology, 28, 1321-1329.

Tang, L.; Li, X.; Wa, L.; Xiao, Y.; Zeng, X. & Ding, H. (2019). Herbal Medicines for Irinotecan-Induced Diarrhea. Frontiers in Pharmacology, 10, 182.

Temponi, V. S.; Silva, J. B.; Alves, M. S.; Ribeiro, A.; Pinho, J. J. R. G.; Yamamoto, C. H.; Pinto, M. A. O.; Del-Vechio-Vieira, G. & Sousa, O. V. (2012). Antinociceptive and anti-inflammatory effects of ethanol extract from Vernonia polyanthes leaves in rodents. International Journal of Molecular Sciences, 13(3), 3887-3899.

Trang, D. T.; Hoang, T. K.; Nguyen, T. T. M.; Cuong, P.; Dang, N. H.; Dang, H. D.; Quang, T. N. & Dat, N. T. (2020). Essential Oils of lemongrass (Cymbopogon citratus Stapf) induces apoptosis and cell cycle arrest in A549 lung cancer cells. BioMed Research International., 2020, 1-8.

Tung, Y. T.; Wu, M. F.; Lee, M. C.; Wu, J. H.; Huang, C. C. & Huang, W. C. (2019). Antifatigue activity and exercise performance of phenolic-rich extracts from Calendula officinalis, Ribes nigrum, and Vaccinium myrtillus. Nutrients, 11(8), 1715.

Uliana, M. P.; Fronza, M.; Silva, G. A.; Vargas, T. S.; Andrade, T. U. & Scherer, R. (2016). Composition and biological activity of Brazilian rose pepper (Schinus terebinthifolius Raddi) leaves. Industrial Crops and Products, 83, 235-240.

Valverde, S. V.; Oliveira, T. B. & Souza, S. P. (2012). Solidago chilensis Meyen (Asteraceae). Revista Fitos, 7(3), 131-136.

World Health Organization. (1998). Bulletin of the World Health Organization. Regulatory situation of herbal medicines. A worldwide review. Disponivel em: https://apps.who.int/iris/handle/10665/63801. Acesso em 5 dez. 2021.

Yao, C. H.; Yeh, J. Y.; Chen, Y. S.; Li, M. H. & Huang, C. H. (2017). Wound-healing effect of electrospun gelatin nanofibres containing Centella asiática extract in a rat model. Journal of Tissue Engineering and Regenerative Medicine, 11(3), 905-915.

Zoofishan, Z.; Kúsz, N.; Csorba, A.; Tóth, G.; Hajagos-Tóth, J.; Kothencz, A.; Gáspár, R. & Hunyadi, A. (2019). Antispasmodic activity of prenylated phenolic compounds from the root bark of Morus nigra. Molecules, 24(13), 2497.



How to Cite

CUSTÓDIO , A. C.; CAETANO, G. de P. dos S.; ALMEIDA, M. R. de. Evaluation of the traditional use and commerce of medicinal plants and phythoterapics in the municipality of Resende, RJ: A contribution to the development of the National Policy on Medicinal Plants and Phythoterapics in Sul Fluminense . Research, Society and Development, [S. l.], v. 11, n. 2, p. e15211225423, 2022. DOI: 10.33448/rsd-v11i2.25423. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/25423. Acesso em: 29 feb. 2024.



Health Sciences