Takotsubo cardiomyopathy as a differential diagnosis of acute coronary syndrome: differences between clinical features





Takotsubo cardiomyopathy; Acute coronary syndrome; Differential diagnosis; Clinical manifestations.


Objective: To demonstrate the importance of having Takotsubo Cardiomyopathy (TC) as a differential diagnosis for acute coronary syndrome (ACS), through the analysis of the clinical aspects of this condition. Methods: Integrative literature review that sought to answer the question "How is the diagnosis of patients with Takotsubo cardiomyopathy, differentiating from Acute Coronary Syndrome, based on the clinical presentation?", developed through the PICo strategy and whose articles were searched in the databases sources: Medical Literature and Retrieval System onLine (MEDLINE/PubMed®) via National Library of Medicine; Scientific Electronic Library Online (SciELO) and Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). Results: Patients with TC were predominantly women, with a mean age between 60 and 70 years in more than 90% of the cases and they presented similarities to ACS, which presents a challenge in differentiating the two. The clinical pictures are similar due to the presence of chest pain and dyspnea, including changes in the ECG and cardiac biomarkers, in addition to presenting similar data on mortality and in-hospital complications. Electrocardiographic alterations, although present in both conditions, present different patterns. Conclusion: The two conditions, TC and ACS, have very similar clinical presentations, and the first should be investigated as a differential diagnosis of the second. For the differentiation of the two and diagnostic confirmation of Takotsubo cardiomyopathy, the Mayo criteria must be considered, through the help of complementary exams, such as electrocardiogram and echocardiography.


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How to Cite

MENDES, I. P. G.; FONSECA NETO, O. J.; SANTANA, B. V. R. C. .; SOUZA, J. L. de; VIANA, B. L. A. .; CORREIA, R. S.; ARAUJO, H. J. B. .; KRÜGER, Y. da S. .; MENDES, Érica de A. S. .; MOITA, A. N. C. . Takotsubo cardiomyopathy as a differential diagnosis of acute coronary syndrome: differences between clinical features. Research, Society and Development, [S. l.], v. 11, n. 2, p. e8111225514, 2022. DOI: 10.33448/rsd-v11i2.25514. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/25514. Acesso em: 2 mar. 2024.



Review Article