Clinical outcomes of elderly hospitalized with COVID-19

Authors

DOI:

https://doi.org/10.33448/rsd-v11i2.25622

Keywords:

Aged; Coronavirus; Hospitals; Demographic data; Geriatric nursing.

Abstract

Quantitative documentary aimed to analyze clinical outcomes and sociodemographic and clinical characteristics of elderly hospitalized by Coronavirus (COVID-19). Documental research was realized, with data from Hospital Epidemiology Center on elderly people hospitalized with COVID-19 in 2020. The results show male predominated (50.3%), mean age of 71.9, and multimorbidities (88.8%). In the prognosis, 70.9% were discharged 22.9% died and 6.1% were transferred to other hospitals. At discharges prevailed: mean age of 70.4; male 53.3%, used oxygen support (72.44%), in which 5.5% used mechanical ventilation, were prone (79.53%), had a mean partial pressure of oxygen (PaO2) by 102.79 ± 47.47, D-Dimer of 2016.98 ± 1994.94, and the Computed Tomography (CT) scan with aspect in opacities occurred in 66.79%. In deaths, predominated: mean age of 76.6, female (58.5%), need oxygen therapy in 97.53% of the elderly, use of mechanical ventilation (MV) 58.54% and prone position in 60.98%, mean D-Dimer of 5022.29, Computed Tomography (CT) scan with aspect in opacities in 73.2%. Finally, in discharge and death outcomes the prevalent morbidities: SAH, diabetes Mellitus and cardiovascular disease. The mean age was 70.4 (discharge) and 76.7% (death), 97.53% used oxygen, and 58.54% required intubation.

References

Aquino E. M. L., Silveira I. H., Pescarini J., Aquino R., & Souza-Filho J. Á. (2020). Medidas de distanciamento social no controle da pandemia de COVID-19: potenciais impactos e desafios no Brasil. Ciência & Saúde Coletiva, 25(Supl.1), 2423-2446. https://doi.org/10.1590/1413-81232020256.1.10502020

Backer J., Klinkenberg D. & Wallinga J. (2020). Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28. EuroSurveillance, 25(5):2000062. https://doi.org/10.2807/1560-7917.ES.2020.25.5.2000062

Baltussem A. & Kindler C. H. (2004). Citation classics in critical care medicine. Intensive Care Med, 30(5):90210. https://pubmed.ncbi.nlm.nih.gov/14985952/ doi: 10.1007/s00134-004-2195-7

Barbosa I. R., Galvão M. H. R., Sousa T. A., Gomes M. S., Medeiros A. A., & Lima K. (2020). Incidência e mortalidade por COVID-19 na população idosa brasileira e sua relação com indicadores contextuais: um estudo ecológico. Bras. Geriatr. Gerontol, 23(1):e200171. https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1117772

Bitencourt, G. R., Almeida A. R., Corrêa B. L. M. A. L., Rocha G. S., Souza R. S., Couto V. M., & Santana R. F. (2021). Pronação do Idoso na Covid-19: Considerações de Enfermagem Gerontológica. In: Santana RF (Org.). Enfermagem gerontológica no cuidado do idoso em tempos da COVID 19. Brasília, DF: Editora Aben, 171 p. (Serie Enfermagem e Pandemias, 5). https://doi.org/10.51234/aben.21.e05.c15

Bourouiba L (2020). Turbulent gas clouds and respiratory pathogen emissions – Potential Implications for Reducing Transmission of Covid 19. Jama, 21;323(18):1837-1838. 10.1001/jama.2020.4756

Cellard A. (2012). Análise documental. In Poupart J., Deslauriers J. P., Groulx L. H., Laperrière A., Mayer R., Pires À. A pesquisa qualitativa: enfoques epistemológicos e metodológicos. (3a ed., pp. 295-316), Rio de Janeiro: Vozes.

Chen J., Qi T., Liu L., Ling Y., Qian Z., Li T., Li F., Xu Q., Zhang Y., Xu S., Song Z., Zeng Y., Shen Y., Shi Y., Zhu T., & Lu H. (2020). Clinical progression of patients with COVID-19 in Shanghai, China. J Infect, 80(5):e1-e6. https://doi: 0.1016/j.jinf.2020.03.004.

Chen J., Qi T., Liu L., Du H., Lin H., Chen C., Rao S., Yu R., Wang J., Xue Z., Zhang Y., & Xie Y. (2020). Clinical progression of patients with COVID-19 in Shanghai, China. European Journal Inflammation, 80(5):e1-e6. https://journals.sagepub.com/doi/pdf/10.1177/20587392211027083

Docherty A. B., Harrison E. M., Green C. A., Hardwick H. E., Pius R., Norman L., Holden K. A., Read J. M., Dondelinger F., Carson G., Merson L., Lee J., Plotkin D., Sigfrid L., Halpin S., Jackson C., Gamble C., Horby P. W., Nguyen-Van-Tam J. S., & K., Semple M. G. (2020). Features of 20 133 hospitalized UK patients with COVID-19 using the ISARIC WHO Clinical Characterization Protocol: prospective observational cohort study. BMJ, 369:m1985. 10.1136/bmj.m1985

Gao Y., Li T., Han M., Li X., Xu Y., Zhu Y., Liu Y., Wang X., & Wang L. (2020). Diagnostic utility of clinical laboratory data determinations for patients with the severe Covid-19. J Med Virol, 92(7):791-796. 10.1002/jmv.25770

GIL, A. C. (2008). Métodos e técnicas de pesquisa social. Atlas.

Gil-Rodrigo A., Miró Ò., Piñera P., Jiménez S., Martín A., Martín-Sánchez F. J., Jacob J., Guardiola J. M., García-Lamberechts E. J., Espinosa B., Mojarro E. M., Tejera M. G., Serrano L., Agüera C., Soy E., Llauger L., Juan M. A., Palau A., & Alquézar-Arbé A. (2020). Analysis of clinical characteristics and outcomes in patients with COVID-19 based on a series of 1000 patients treated in Spanish emergency departments. Emergencias (Sant Vicenç dels Horts), 32(4):233-41. https://pubmed.ncbi.nlm.nih.gov/32692000/

Grasselli G., Greco M., Zanella A., Albano G., Antonelli M., Bellani G., Bonanomi E., Cabrini L., Carlesso E., Castelli G., Cattaneo S., Cereda D., Colombo S., Coluccello A., Crescini G., Molinari A. F., Foti G., Fumagalli R., Iotti G. A., & Cecconi M. (2020). Risk factors associated with mortality among patients with COVID-19 in intensive care Units in Lombardy, Italy. JAMA Intern Med, 3];180(10):1345- 55. 10.1001/jamainternmed.2020.3539

Guan W. J, Liang W. H., Zhao Y., Liang H. R., Chen Z. S., Li Y. M., Liu X. Q., Chen R. C., Tang C. L., Wang T., Ou C. Q., Li L., Chen P. Y., Sang L., Wang W., Li J. F., Li C. C., Ou L. M., Cheng B., & He J. X. (2020). Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. Eur Respir J., 55(5):2000547. https://doi. org/10.1183/13993003.00547-2020

Guan W. J., Liang W. H., Zhao Y., Liang H. R., Chen R. C., Tang C. L., Wang T., Ou C. Q., Li L., Chen P. Y., Sang L., Wang W., Li J. F., Li C. C., Ou L. M., Cheng B., Xiong W., Ni Z. Y., Xiang J., & He J. X. (2020). China Medical Treatment Expert Group for COVID-19. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. Eur Respir J, 55(5):2000547. 10.1183/13993003.00547-2020

Guan W. J., Ni Z. Y., Hu Y., Liang W. H.. Ou C. Q., He J. X., Liu L., Shan H., Lei C. L., Hui D. S. C., Du B., Li L. J., Zeng G., Yuen K. Y., Chen R. C., Tang C. L., Wang T., Chen P. Y., Xiang J., & Zhong N. S. (2020). Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med, 382:1708-20. 10.1056/NEJMoa2002032

Gupta S., Hayek S. S., Wang W., Chan L., Mathews K. S., Melamed M. L., Brenner S. K., Leonbérg-Yoo A., Schenck E. J., Radbel J., Reiser J., Bansal A., Srivastava A., Zhou Y., Sutherland A., Green A., Shehata A. M., Goyal N., Vijayan A., & Leaf D. E. (2020). Factors associated with death in critically Ill patientsoronavírusavirus disease 2019 in the US. JAMA Intern Med, 180(11):1436-46. 10.1001/jamainternmed.2020.3596

Hammerschmidt K. S. A. & Santana R. F. (2020). Saúde do idoso em tempos de pandemia covid-19. Cogitare enfermagem, 25:e72849. https://revistas.ufpr.br/cogitare/article/view/72849/pdf

Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y., Zhang L., Fan G., Xu J., Gu X., Cheng Z., Yu T., Xia J., Wei Y., Wu W., Xie X., Yin W., Li H., Liu M., & Cao B. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lan – cet, 395:497-506. 10.1016/S0140-6736(20)30183-5

Lakatos, E. M. & Marconi, M. A. (1191). Técnicas de pesquisa. In Lakato E. M., Marconi, M. A. Fundamentos de Metodologia Científica. (3a ed.), 95-200, Atlas.

Livingston E. & Bucher K. (2020). Coronavirus Disease 2019 (COVID-19) in Italy. JAMA, 323(14):1335. https://pubmed.ncbi.nlm.nih.gov/32181795/

Ministério da Saúde (BR). (2020a). COVID-19 – Painel Coronavírus. MS. https:// covid.saude.gov.br/

Ministério da Saúde (BR). (2010). Portaria nº 2.254, de 5 de agosto de 2010. Institui a Vigilância Epidemiológica em Âmbito Hospitalar, define as competências para a União, os Estados, o Distrito Federal, os Municípios, os critérios para a qualificação das unidades hospitalares de referência nacional e define também o escopo das atividades a serem desenvolvidas pelos Núcleos Hospitalares de Epidemiologia. Diário Oficial da União. Brasília, DF, 6 ago. 2021. Seção 1. p. 55.

Ministério da Saúde (BR). (2020b). Protocolo de Manejo Clínico do Coronavírus (COVID-19) na Atenção Primária à Saúde. (v9). Secretaria de Atenção Primária à Saúde (SAPS). Brasília. https://portaldeboaspraticas.iff.fiocruz.br/biblioteca/protocolo-de-manejo-clinico-docoronavirus-covid-19-na-atencao-primaria-a-saude/

Ministério da Saúde (BR). (2020d). Secretaria de Ciência, Tecnologia, Inovação e Insumos Estratégicos em Saúde. Coronavírus COVID-19: diretrizes para diagnóstico e tratamento da COVID-19 [Internet]. Versão 4. Brasília: MS. https://portalarquivos. saude.gov.br/images/pdf/2020/May/08/DiretrizCovid19-v4-07-05.20h05m.pdf

Ministério da Saúde (BR). (2020c). Secretaria de Vigilância em Saúde. Boletim Epidemiológico Especial 16. https://www.saude.gov.br/images/pdf/2020/May/21/2020-05-19---BEE16---Boletimdo-COE-13h.pdf

Ministério da Saúde (BR). (2021a). Secretaria de Vigilância em Saúde. Boletim Epidemiológico Especial. Doença pelo Coronavírus COVID-19. Semana Epidemiológica (21 a 27/2/2021). https://www.gov.br/saude/pt br/media/pdf/2021/marco/05/boletim_epidemiologico_covid_52_final2.pdf

Moreira S. V. (2009). Análise documental como método e como técnica. In Duarte J., Barros A., (Orgs). Métodos e técnicas de pesquisa em comunicação. pp. 269-79, Atlas.

National Institutes of Health. (2020). Covid-19 Treatment Guidelines Panel. Coronavirus Disease 2019 (Covid-19). Treatment Guidelines. http://www.covid19treatmentguidelines.nih.gov.

Ng S. C. & Tilg H. (2020). Covid-19 and the gastrointestinal tract: more than meets the eye. Gut, 69(9):973-974 10.1136/gutjnl-2020-321195

Niquini P. R., Lana R. M., Pacheco A. G., Cruz O. G., Coelho F. C., Carvalho L. M., Villela D. A. M., Gomes M. F. C., & Bastos L. M. (2020). SRAG por COVID-19 no Brasil: descrição e comparação de características demográficas e comorbidades com SRAG por influenza e com a população geral. Cadernos de Saúde Pública., 36(7):e00149420. https://doi.org/10.1590/0102-311X00149420

Oliveira A. C., Lucas T. C., & Iquiapaza R. A. (2020). O que a pandemia da covid-19 tem nos ensinado sobre adoção de medidas de precaução? Texto contexto Enferm, 29:e20200106. https://doi.org/10.1590/1980-265x-tce-2020-0106.

Organização das Nações Unidas (ONU) (1950-2020). (2019) World population prospects 2019. Estimates. https://population.un.org/wpp/ Download/Standard/Population

Recovery Collaborative Group, Horby P., Lim W. S., Emberson J. R., Mafham M., Bell J. L., Linsell L., Staplim N., Brightling C., Ustianowski A., Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, & Landray M (2020). Dexamethasone in Hospitalized Patients withCovid-19. N Engl J Med, 384:693-704. 10.1056/NEJMoa2021436

Richardson S., Hirsch J. S., Narasimhan M., Crawford J. M., Mcginn T., & Davidson K. W. (2020). COVID-19 Research Consortium. Presenting characteristics comorbidities and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area. JAMA, 323(20):2052. http://dx.doi.org/10.1001/jama.2020.6775

Rodriguez-Morales J. Á., Cardona-Ospina J. Á., Gutiérrez-Ocampo E., Villamizar- Peña R., Holguin-Riviera Y., Escalera-Antezana J. P., Alvarado-Arnez L. E., Bonilla-Aldana D. K., Franco-Paredes C., Henao-Martinez A. F., Paniz-Mondolfi A., Lagos-Grisales G. J., Ramírez-Vallejo E., Suárez J. Á., Zambrano L. I., Villami-Gómez, W. E., Balbin-Ramon G. J., Rabaan A. A., Harapan H., Dhama K., . & Sah R. (2020). Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Medicine and Infectious Disease, 34, 1016232. https://doi.org/10.1016/j.tmaid.2020.101623.

Secretaria Estadual de Saúde do Paraná (SESA). Boletim Epidemiológico. Paraná, Brasil. https://www.saude.pr.gov.br/Pagina/Coronavirus-COVID-19

Secretaria Municipal de Saúde de Curitiba (SMS) (2020). Centro de epidemiologia. Painel COVID 19 Curitiba. Paraná, Brasil. https://datastudio.google.com/u/1/reporting/3f45a263-ae46-45be-9efc-a9e47b358dd4/page/6x9zB

Song F., Shi N., Shan F., Zhang Z., Shen J., Lu H., Ling Y., Jiang Y., & Shi Y. (2020). Emerging 2019 Novel Coronavirus (2019-nCoV pneumonia). Radiology, 295(1):210-7. 10.1148/radiol.2020200274

Suleyman G., Fadel R. A., Mallete K. M., Hamond C., Abdulla H., Entz A., Demertzis Z., Hanna Z., Failla A., Dagher C., Chaudhry Z., Vahia A., Lanfranco A. O., Ramesh M., ZervOS M. J., Alangaden G., Miller J., & Brar I. (2020) Clinical characteristics and morbidity associated with coronavírus disease 2019 in a Serie of patients in metropolitan Detroit. JAMA Netw Open, 3(6):e2012270. 10.1001/jamanetworkopen.2020.12270

Wang D., Hu B., Hu C., Zhu F., Liu X., Zhang J., Wang B., Xiang H., Cheng Z., Xiong Y., Zhao Y., Li Y., Wang X., & Peng Z. (2020). Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan. JAMA, 323(11):1061-9. 10.1001/jama.2020.1585

Wijaya I., Rizky A. & Huang I. (2020). The Use of Therapeutic-Dose Anticoagulation and Its Effect on Mortality in Patients With COVID-19: A Systematic REVIEW. Clinical and Applied Thrombosis/Hemostasis, Sage journals, 26:1076029620960797. https://doi.org/10.1177/1076029620960797

World Health Organization (WHO). (2020). Corticosteroids for COVID-19. Geneva: WHO. https://www.who.int/publications/i/item/WHO- -2019-nCoV-Corticosteroids-2020.1

World Health Organization (WHO). (2021). Covid-19. Geneva: WHO. https://www.who.int/publications/i/item/WHO- -2019-nCoV.

Xu X., Yu C., Qu, J., Zhang L., Jiang S., Huang D., Chen B., Zhang Z., Guan W., Ling Z., Jiang R., Hu T., Ding Y., Lin L., Gan Q., Luo L., Tang X., Liu J. (2020). Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2. European Journal of Nuclear Medicine and Molecular Imaging, 47:1275–1280. 10.1007/s00259-020-04735-9

Yang G., Zhang H. & Yang Y (2020). Challenges and Countermeasures of Integrative Cancer Therapy in the Epidemic of COVID-19. Integr Cancer Ther, 19 :1534735420912811. 10.1177/1534735420912811

Zhang L., Zhu F., Xie L., Wang C., Wang J., Chen R., Jia P., Guan H. Q., Peng L., Chen Y., Peng P., Zhang P., Chu Q., Shen Q., Wang Y., Xu S. Y., Zhao J. P., & Zhou M. (2020). Clinical characteristics of COVID-19- infected cancer patients: a retrospective case study in three hospitals within Wuhan. Ann Oncol, 31(7):894–901]. 10.1016/j.annonc.2020.03.296

Zheng Y., Yang J., Gou X., Pu K., Chen Z., Guo Q., Ji R,, Wang H., Wang Y., & Zhou Y. (2020). Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis, 94:91-5. 10.1016/j.ijid.2020.03.017

Zhou F., Yu T., Du R., Fan G., Liu Y., Liu Z., Xiang J., Wang Y., Song B., Gu X., Guan L., Wei Y., Li H., Wu X., Xu J., Tu S., Zhang Y., Chen H., & Cao B. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet, 395(10229):1054-62. 10.1016/S0140-6736(20)30566-3

Published

24/01/2022

How to Cite

PAULA, A. da S. .; HAMMERSCHMIDT, K. S. de A. .; LENARDT, M. H. .; FUGAÇA, N. P. A. .; SOUZA, A. O. de .; LACHOUSKI, L. Clinical outcomes of elderly hospitalized with COVID-19. Research, Society and Development, [S. l.], v. 11, n. 2, p. e24811225622, 2022. DOI: 10.33448/rsd-v11i2.25622. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/25622. Acesso em: 20 feb. 2024.

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Health Sciences