Preparation and Characterization of Hydroxyapatite by the precipitation method and heat treatment




Hydroxyapatite; Characterization; Precipitation.


Hydroxyapatite is a synthetic substance in the form of microspheres composed of calcium and phosphate, present in human bones and tooth enamel. The objective of the work was to synthesize hydroxyapatite, from the solution of calcium nitrate and diamonic phosphate by the method of precipitation and heat treatment, obtaining the hydroxyapatite in powder form. To study its structural evolution, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and Raman spectroscopy were used. The results show that the hydroxyapatite nanocrystalline can be successfully produced by the precipitation technique from raw materials.


Aoki, H. (1991). Science and medical applications of hydroxyapatite, 1.ed., 11.

Best, S & Bonfield, W. J. (1994). Processing behaviour of hydroxyapatite powders with contrasting morphology. Journal of Materials Science: Materials in Medicine volume 5, pages516–521.

Brundavanam, R. K. et al. (2013). Modelling the Crystal Structure of a 30 nm Sized Particle based Hydroxyapatite Powder Synthesised under the Influence of Ultrasound Irradiation from X-ray powder Diffraction Data. American Journal of Materials Science, v. 3, nº 4, p. 84-90.

Gomes, D. S. et al. (2019). A brief review on hydroxyapatite production and use in biomedicine. Cerâmica (65), 282-302.

Han, Y. et al. (2004). Syntesis and Sintering of nanocrystalline Hidroxyapatite powders by citric acid sol-gel combustion method. Mater. Res. Bull. 39, 25–32.

K.C.B. Yeong, J. Wang, S.C. Ng. (1999). Fabricating densified hydroxyapatite ceramics from a precipitated precursor. Materials LettersVolume 38, Issue 3, Pages 208-213.

LeGeros, R. Z. (1993). Biodegradation and bioresorption of calcium phosphate ceramics. Clinical Materials,V. 14, Pages 65-88

Saeri, M.R. et al (2003). The wet precipitation process of hydroxyapatite. Material Letters. v 57, p 4064-4069.

Stupp, S.I. & Ciegler, G.W. (1992) Organoapatites: Materials for artificial bone. I. Synthesis and microstructure. Journal of Biomedical Materials Research, Vol. 26, 169-183.

Suchanek, W, Yoshimura, M & Mater, J. (1998). Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants Res. 13 pp. 94-117.

Tas, A.C. (2001). X-raydiffraction data for flux-growncalciumhydroxyapatitewhiskers. Powder Difraction, v. 16, nº 2, p. 102-106.

Torres-Gallegos, I. et, al.(2012). Enamel roughness and depth profile after phosphoric acid etching of healthy and fluorotic enamel. Australian Dental Journal, 57, p. 151 – 156.




How to Cite

GOMES, F. D. C.; AMORIM, J. D. P. de; SILVA, G. S. da; SOUZA, K. C. de; PINTO, A. F.; SANTOS, B. S.; COSTA, A. F. de S. Preparation and Characterization of Hydroxyapatite by the precipitation method and heat treatment. Research, Society and Development, [S. l.], v. 9, n. 6, p. e172963549, 2020. DOI: 10.33448/rsd-v9i6.3549. Disponível em: Acesso em: 30 jan. 2023.



Exact and Earth Sciences