Effects of High-Intensity Interval Training on glycemic control and body composition of individuals with Type 2 Diabetes mellitus: An integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v12i7.42544

Keywords:

High-Intensity Interval Training; Glycemic control; Body composition; Diabetes Mellitus, Type 2.

Abstract

Type 2 Diabetes Mellitus (DM2) is characterized by resistance and inadequate production of insulin by the pancreas, and is associated with factors such as obesity and a sedentary lifestyle. The treatment involves changes in lifestyle, such as exercise, and, in some cases, the use of medication, and continuous control is required. In this sense, High Intensity Interval Training (HIIT) is a promising alternative physical treatment. This study aims to investigate the effects of HIIT on glycemic control and body composition of individuals with DM2. This is a descriptive literature review, in which randomized controlled trials were included, available for reading in full, published between 2013 and 2023 in English and Portuguese languages, with methodological quality evaluated according to the PEDro Scale. The review included a total of 86 participants, with the number ranging from 16 to 37 in each study. The percentage of participants by gender was not balanced (M=60; F=26). HIIT sessions lasting 11-12 weeks were conducted. Exercise intensity was controlled using different measures, such as maximum heart rate and peak work rate. The analysis of the adjacent literature confirmed the effectiveness of HIIT for DM2 in the parameters addressed, despite some divergence. Improvement was also observed in other measures such as fitness and cardiovascular risk. However, the lack of standardization in training protocols makes future research necessary to provide more solid and detailed evidence on the effects of HIIT in this population.

References

Alvarez, C., Ramirez-Campillo, R., Martinez-Salazar, C., Mancilla, R., Flores-Opazo, M., Cano-Montoya, J., & Ciolac, E.G. (2016). Low-Volume High-Intensity Interval Training as a Therapy for Type 2 Diabetes. International journal of sports medicine, 37(9), 723–729.

Álvarez, C., Ramírez-Campillo, R, Ramírez-Vélez, R, & Izquierdo, M. (2017). Effects and prevalence of nonresponders after 12 weeks of high-intensity interval or resistance training in women with insulin resistance: a randomized trial. Journal of applied physiology (Bethesda, Md.: 1985), 122(4), 985–996.

Bubolz, I. S., & Ostolin, T. L. V. P. (2022). Os efeitos do treinamento intervalado de alta intensidade em indivíduos com diabetes do tipo 2: uma revisão de escopo. Revista Brasileira de Prescrição e Fisiologia do Exercício. 16(106), 568-584.

Cobas, R. Rodacki, M., Giacaglia, L., Calliari, L. E. P., Noronha, R. M., Valerio, C., Custódia, J., Scharf, M., Barcelos, C. R. G., Tomarchio, M. P., Silva, M. E. R., Santos, R. F., Zajdenverg, L., & Gabbay, M. (2022). Diagnóstico do diabetes e rastreamento do diabetes tipo 2. Diretriz Oficial da Sociedade Brasileira de Diabetes.

Filho, A. A. M., & Oliveira, V. K. (2023) Índice HOMA: O Que É Isso? ABC Med.

Francois, M. E., Durrer, C., Pistawka, K. J,, Halperin, F. A., Chang, C., & Little, J. P. (2017). Combined Interval Training and Post-exercise Nutrition in Type 2 Diabetes: A Randomized Control Trial. Frontiers in Physiology. 8(528).

Gentil, P., Silva, L. R. B. E., Antunes, D. E., Carneiro, L. B., de Lira, C. A. B., Batista, G., de Oliveira, J. C. M., Cardoso, J. S., Souza, D. C., & Rebelo, A. C. S. (2023). The effects of three different low-volume aerobic training protocols on cardiometabolic parameters of type 2 diabetes patients: A randomized clinical trial. Frontiers in endocrinology, 14, 985404.

Hansen, D., Dendale, P., Jonkers, R.A., Beelen, M., Manders, R.J., Corluy, L., Mullens, A., Berger, J., Meeusen, R., & Van Loon, L.J. (2009). Continuous low- to moderate-intensity exercise training is as effective as moderate- to high-intensity exercise training at lowering blood HbA(1c) in obese type 2 diabetes patients. Diabetologia. 52(9), 1789-1797.

Kanaley, J. A., Colberg, S. R., Corcoran, M. H., Malin, S. K., Rodriguez, N. R., Crespo, C. J., Kirwan, J. P., & Zierath, J. R. (2022). Exercise/Physical Activity in Individuals with Type 2 Diabetes: A Consensus Statement from the American College of Sports Medicine. Med Sci Sports Exerc, 54(2), 353–368.

Koh, H-C. E., Ørtenblad, N., Winding, K.M. Hellsten, Y., Mortensen, S. P., Nielsen, J. (2018). High-intensity interval, but not endurance, training induces muscle fiber type-specific subsarcolemmal lipid droplet size reduction in type 2 diabetic patients. Am J Physiol Endocrinol Metab, 315, 872-884.

Li, J., Cheng, W., & Ma, H. (2022). A Comparative Study of Health Efficacy Indicators inSubjects with T2DM Applying Power Cycling to 12 Weeks of Low-Volume High-Intensity Interval Training and Moderate-Intensity Continuous Training. Journal of Diabetes Research, 2022(9273830), 1-13.

Liu, J.X., Zhu, L., Li, P.J., Li, N., & Xu, Y.B. (2019). Effectiveness of high-intensity interval training on glycemic control and cardiorespiratory fitness in patients with type 2 diabetes: a systematic review and meta-analysis. Aging Clinical and Experimental Research. 31, 575-593.

Madsen, S.M., Thorup, A.C., Overgaard, K., & Jeppesen, P.B. (2015). High Intensity Interval Training Improves Glycaemic Control and Pancreatic β Cell Function of Type 2 Diabetes Patients. PLOS ONE, 10(8), 1-24.

Magalhães, J.P., Hetherington-Rauth, M., Júdice, P. B., Correia, I. R., Rosa, G. B., Heenriqie-Neto, D., Melo, X., Silva, A. M., & Sardinha, L. B. (2021). Interindividual Variability in Fat Mass Response to a 1-Year Randomized Controlled Trial With Different Exercise Intensities in Type 2 Diabetes: Implications on Glycemic Control and Vascular Function. Frontiers in Physiology, 12(698971), 1-10.

Mello, M.B., Righi, N.C., Schuch, F.B., Signori, L.U., & Silva, A.M.V. (2022). Effect of high-intensity interval training protocols on VO2max and HbA1c level in people with type 2 diabetes: A systematic review and meta-analysis. Annals of Physical and Rehabilitation Medicine. 65(5), 101586.

Mendes, R., Sousa, N., Themudo-Barata, J.L., & Reis, V.M. (2019). High-Intensity Interval Training Versus Moderate-Intensity Continuous Training in Middle-Aged and Older Patients with Type 2 Diabetes: A Randomized Controlled Crossover Trial of the Acute Effects of Treadmill Walking on Glycemic Control. International Journal of Environmental Research and Public Health, 16(21), 4163.

Methley, A. M., Campbell, S., Chew-Graham, C., McNally, R., & Cheraghi-Sohi, S. (2014). PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews. BMC Health Services Research, 14 (579), 1-10.

Ministério da Saúde. (2009). Diabetes. Biblioteca Virtual em Saúde. Recuperado de: https://bvsms.saude.gov.br/diabetes/.

Ministério da Saúde. (2020a). Relatório de recomendação: Protocolos Clínicos e Diretrizes Terapêuticas. Brasília. https://www.sbn.org.br/fileadmin/user_upload/Relatorio_PCDT_Diabetes_Melito_Tipo_2_CP_33_2020.pdf.

Ministério da Saúde. (2020b). Protocolo clínico e diretrizes terapêuticas do diabete melito tipo 2. Recuperado de https://www.gov.br/conitec/pt-br/midias/protocolos/resumidos/pcdt_resumido_diabete-melito_tipo2.pdf

Ministério da Saúde. (2020c). 26/6 – Dia Nacional do Diabetes. Recuperado de https://bvsms.saude.gov.br/26-6-dia-nacional-do-diabetes-4/.

Padovani, C., Arruda, R.M.C., & Sampaio, L.M.M. (2022). Efeitos dos treinamentos combinado e intervalado de alta intensidade no controle glicêmico e na aptidão física em pacientes diabéticos do tipo 2: uma revisão sistemática. Revista Brasileira de Prescrição e Fisiologia do Exercício. 16(106), 634-644.

Petersen, M. H., de Almeida, M. E., Wentorf, E. K., Jensen, K., Ørtenblad, N., & Højlund, K. (2022). High-intensity interval training combining rowing and cycling efficiently improves insulin sensitivity, body composition and VO2max in men with obesity and type 2 diabetes. Frontiers in endocrinology, 13, 1032235.

Santos, C. M. C., Pimenta, C. A. M., & Nobre, M. R. C. (2007). A Estratégia Pico para a Construção da Pergunta de Pesquisa e Busca de Evidências. Rev Latino-am Enfermagem, 15(3), 1-4.

Shaban N., Kenno K.A., & Milne K.J. (2014). The effects of a 2 week modified high intensity interval training program on the homeostatic model of insulin resistance (HOMA-IR) in adults with type 2 diabetes. The Journal of sports medicine and physical fitness, 54(2), 203–209.

Shiwa, S. R., Costa, L. O. P., Moser, A. D. L., Aguiar, I. C., & Oliveira, L. V. O. (2011). PEDro: a base de dados de evidências em fisioterapia. Fisioter Mov., 24(3), 523-533.

Silva, R. P., & Benedet, J. (2017). Treinamento Intervalado de Alta Intensidade e Emagrecimento. UNIEDU. http://www.uniedu.sed.sc.gov.br/wp-content/uploads/2017/08/TCC-Robert-Passos-da-Silva-OK.

Silva, W. S. Jr, Fioretti, A. M. B., Vancea, D. M. M., Macedo, C. L. D. & Zagury, R. (2021). Atividade física e exercício no pré-diabetes e DM2. Diretriz Oficial da Sociedade Brasileira de Diabetes. Recuperado de: https://diretriz.diabetes.org.br/atividade-fisica-e-exercicio-no-pre-diabetes-e-dm2/#introducao.

Sudarsono, N. C., Tulaar, A. B. M., Jusman, S. W. A., Soewondo, P., Sudaryo, D. K., Siagian, M., & Karhiwikarta, W. (2019). The Effects of Combined High-Intensity Interval and Resistance Training on Glycemic Control and Oxidative Stress in T2DM. Asian J Sports Med, 10(3), 1-7.

Whittemore, R., & Knafl, K. (2005). The integrative review: updated methodology. Journal of Advanced Nursing, 52(5), 546–553.

Published

19/07/2023

How to Cite

ALCÂNTARA, M. K. B.; ADELINO, M. H. R.; MOTTA, A. B. A. .; RODRIGUES, B. M. A.; FARIAS, V. B. de; RAPOSO, M. C. B.; SOUZA, I. T. C. de. Effects of High-Intensity Interval Training on glycemic control and body composition of individuals with Type 2 Diabetes mellitus: An integrative literature review. Research, Society and Development, [S. l.], v. 12, n. 7, p. e9712742544, 2023. DOI: 10.33448/rsd-v12i7.42544. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/42544. Acesso em: 15 may. 2024.

Issue

Section

Review Article