Characterization of patients with low health literacy using warfarin

Authors

DOI:

https://doi.org/10.33448/rsd-v12i10.43391

Keywords:

Warfarin; Atrial fibrillation; Health literacy; Hospitals.

Abstract

Introduction: Health literacy (HL) is considered a factor that interferes with warfarin treatment, since the literature indicates an association between low understanding of the treatment and inadequate control of oral anticoagulation. The study aimed to characterize patients with low functional health literacy in an anticoagulation clinic in Minas Gerais. Methodology: The work was carried out at the anticoagulation outpatient clinic at the UFMG clinic hospital. Participants signed the consent form, respecting the precepts of bioethics. Individuals with inadequate TTR values (TTR <60%) and low functional health literacy were included. Numerical variables were described taking into account the mean and standard deviation and categorical variables according to percentile distribution. Results: The study presents elderly females residing in Belo Horizonte and the metropolitan region as the majority population. Participants had an average study time of 3.9 years and 19.6% of those involved reported not knowing how to read. Still, 37.3% reported that they had had a stroke prior to hospitalization and 19.6% had Chagas cardiomyopathy. Polypharmacy was detected in 84.3% of the participants, 58.8% had a high complexity of pharmacotherapy and the average number of medications in continuous use was 6.5. Conclusion: The data obtained in this study reinforce the fragility of patients with low health literacy, leading to the need to implement care and follow-up strategies for these patients in search of equity in health care.

References

Al Alshaikh, S. et al. (2016). Predictive factors of non-adherence to secondary preventative medication after stroke or transient ischaemic attack: A systematic review and meta-analyses. Eur Stroke J., 1 (2), 65-75. 10.1177/2396987316647187.

Alencar, M. M. F. et al. (2020). Epidemiology of acute Chagas Diseases in Brazil from 2007 to 2018. Research, Society and Development, 9(10). 10.33448/rsd-v9i10.9120.

Apolinario, D. et al. (2012). Short Assessment of Health Literacy for Portuguese-speaking Adults. Rev Saúde Pública, 46(4), 702-711. 10.1590/S0034-89102012005000047.

Beauchamp, A. et al. (2015). Distribution of health literacy strengths and weaknesses across socio-demographic groups: a cross-sectional survey using the Health Literacy Questionnaire (HLQ). BMC Public Health, 15 (678). 10.1186/s12889-015-2056-z.

Benjamin, E. J. et al. (2019). American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. Circulation, 139 (10), 56-528. 10.1161/CIR.0000000000000659.

Botton, A., Cúnico, S. D., & Strey, M. N. (2017). Diferenças de gênero no acesso aos serviços de saúde: problematizações necessárias. Mudanças, 25 (1), 67-72. 10.15603/2176-1019.

Bradshaw, P. J. et al. (2019). Warfarin Use and Mortality, Stroke, and Bleeding Outcomes in a Cohort of Elderly Patients with non-Valvular Atrial Fibrillation. J Atr Fibrillation, 12 (1), 2155. 10.4022/jafib.2155.

Brunton, L. L. (2012). Goodman & Gilman: As Bases Farmacológicas da Terapêutica. McGraw-Hill. 12: 2080.

Carod-Artal, F. J., & Melo, M., & Vargas, A. P. (2001). Ictus cardioembólico en la enfermedad de Chagas. Rev Neurol, 33 (4), 311-315. 10.33588/rn.3304.2001055.

Carod-Artal, F.J. et al. (2007). Cardioembolic stroke and ischemic small bowel infarction in a Chagas' disease patient. Eur J Neurol, 14 (5), 8. 10.1111/j.1468-1331.2007.01721.x.

Carthery-Goulart, M. T. et al. (2009) Performance of a Brazilian population on the test of functional health literacy in adults. Rev Saude Publ, 43 (4), 631-638. 10.1590/S0034-89102009005000031.

Chehuen, J. A. et al. (2019). Letramento funcional em saúde nos portadores de doenças cardiovasculares crônicas. Revista Ciência & Saúde Coletiva, 24 (3), 1121-1132. 10.1590/1413-81232018243.02212017.

Estrela, C. (2018). Metodologia Científica: Ciência, Ensino, Pesquisa. Editora Artes Médicas.

Gregson, J. et al. (2019). Emerging Risk Factors Collaboration. Cardiovascular Risk Factors Associated With Venous Thromboembolism. JAMA Cardiol, 4(2), 163-173. 10.1001/jamacardio.2018.4537.

Holbrook, A. M. et al. Systematic overview of warfarin and its drug and food interactions. Arch Intern Med, 165(10), 1095-1106. 0.1001/archinte.165.10.1095.

Johansson, M. (2019). Alcohol Consumption and Risk of First-Time Venous Thromboembolism in Men and Women. Thromb Haemost. Thieme: Thrombosis and Haemostasis, 119(6). 1962-970. 0.1055/s-0039-1681100.

Lane, D., Skjøth, F., Lip, G., Larsen, T., & Kotecha, D. (2017). Temporal Trends in Incidence, Prevalence, and Mortality of Atrial Fibrillation in Primary Care. Journal of the American Heart Association, 6(5). 10.1161/JAHA.116.005155.

Machado, A. et al. (2015). Letramento em Saúde e Envelhecimento - Foco em condições crônicas de saúde. Atas - Investigação Qualitativa em Saúde, 2, 187-192. Retrieved from https://proceedings.ciaiq.org/index.php/CIAIQ/article/view/520.

Malta, D, et al. (2019). Tendências de indicadores relacionados ao tabagismo nas capitais brasileiras entre os anos de 2006 e 2017. Jornal Brasileiro de Pneumologia, 45(5). 10.1590/1806-3713/e20180384.

Martins, M., et al. (2017) Health literacy and warfarin therapy at two anticoagulation clinics in Brazil. Heart (British Cardiac Society), 103 (14), 1089-1095. 10.1136/heartjnl-2016-310699.

Melchior A. C., Correr, C. J., & Fernandez-llimos, F. (2007). Tradução e validação para o português do Medication Regimen Complexity Index. Arquivos Brasileiros de Cardiologia, 89 (4), 210-218. 10.1590/S0066-782X2007001600001.

Merchán-Haman, E. & Tauil, P. L. (2021). Proposta de classificação dos diferentes tipos de estudos epidemiológicos descritivos. Epidemiol. Serv. Saúde, 30 (1). 10.1590/s1679-49742021000100026.

Mohan, K.M., et al. (2011). Risk and cumulative risk of stroke recurrence: a systematic review and meta-analysis. Stroke, 42 (5), 1489-1494. 10.1161/STROKEAHA.110.602615.

Nicodemo, D., & Godoi, M.P. (2010). Juventude dos anos 60-70 e envelhecimento: estudo de casos sobre feminização e direitos de mulheres idosas. Revista Ciência em Extensão, 6 (1), 40-53. Retrieved from: https://ojs.unesp.br/index.php/revista_proex/article/view/324/341.

OMS. (2015). World report on ageing and health. https://apps.who.int/iris/bitstream/handle/10665/186463/9789240694811_eng.pdf;jsessionid=716035051DCB653B3EBFB0AF6B895F31?sequence=1.

Partridge, L., Deelen, J., & Slagboom, P. E. (2018). Facing up to the global challenges of ageing. Nature, 561 (7721), 45–56. 10.1038/s41586-018-0457-8.

Pereira, A. S. Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica. UFSM. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf.

Pinto, I. V. L., et al. (2016). Avaliação da compreensão da farmacoterapia entre idosos atendidos na Atenção Primária à Saúde de Belo Horizonte, MG, Brasil. Ciência & Saúde Coletiva, 21 (11), 3469–81. 10.1590/1413-812320152111.19812015.

Prefeitura de Belo Horizonte. (2023). Controle do Tabagismo. Retrieved Fev 13, 2021, from https://prefeitura.pbh.gov.br/saude/informacoes/atencao-a-saude/promocao-da-saude/controle-do-tagagismo.

Prefeitura de Belo Horizonte. (2019). Protocolo de anticoagulação ambulatorial de Belo Horizonte. https://prefeitura.pbh.gov.br/sites/default/files/estrutura-de-governo/saude/2019/Protocolo%20da%20rede%20municipal%20de%20anticoagulac%CC%A7a%CC%83o%2022%2003%2019%20%20consulta%20publica.pdf.

Shikdar, S., Vashisht, R., & Bhattacharya, P. T. (2023). International Normalized Ratio (INR). StatPearls. StatPearls Publishing. Retrieved from https://pubmed.ncbi.nlm.nih.gov/29939529/

Published

06/10/2023

How to Cite

SANTOS, C. R. dos .; COSTA, J. M. da .; SILLUZIO, S. P. .; CAMARGOS, M. L. F. .; SOARES, C. L. L. .; CINTRA, L. P. .; MARTINS, M. A. P. .; BERTOLLO, C. M. . Characterization of patients with low health literacy using warfarin. Research, Society and Development, [S. l.], v. 12, n. 10, p. e50121043391, 2023. DOI: 10.33448/rsd-v12i10.43391. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/43391. Acesso em: 14 may. 2024.

Issue

Section

Health Sciences