Adverse reactions of lip fillers with hyaluronic acid

Authors

DOI:

https://doi.org/10.33448/rsd-v12i12.43878

Keywords:

Lip; Face; Injection site reaction.

Abstract

The application of hyaluronic acid in orofacial harmonization represents a significant advancement in contemporary aesthetics and dentistry, offering a versatile and safe therapy to enhance facial aesthetics. This naturally occurring substance in the human body is employed to correct imperfections, enhance contours, and balance aesthetic proportions. However, its application requires deep anatomical knowledge and technical skill, underscoring the importance of personalized treatment for satisfactory results. When carried out by qualified professionals, the use of hyaluronic acid is safe and effective, improving facial aesthetics and patients' quality of life. Nevertheless, it is crucial to acknowledge that adverse reactions can occur, ranging from swelling and pain to more serious complications such as infections or allergic reactions. Therefore, it is imperative that professionals are aware of these possibilities, adopting preventive measures such as strict asepsis, and prepared to address contingencies. Effective communication with patients and thorough assessment are essential strategies to minimize the risk of adverse reactions, thus ensuring the safety and efficacy of orofacial harmonization procedures. Hence, the objective of this work is to present a narrative literature review on the adverse reactions of lip augmentation with hyaluronic acid.

References

Abatangelo, G., Vindigni, V., Avruscio, G., Pandis, L., & Brun, P. (2020). Hyaluronic Acid: Redefining Its Role. Cells, 9(7), 1743.

Bukhari, S. N. A., Roswandi, N. L., Waqas, M., Habib, H., Hussain, F., Khan, S., Sohail, M., Ramli, N. A., Thu, H. E., & Hussain, Z. (2018). Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects. International journal of biological macromolecules, 120(Pt B), 1682–1695.

Cotofana, S., Hong, W. J., Horne, J., Harris, S., Surek, C. C., Frank, K., Alfertshofer, M., Kattil, P. K., Sakuma, T., Onishi, E. C., Bertucci, V., Green, J. B., Smith, M. P., Khan, A., & Lowry, N. (2023). Intralabial Lip Compartments and their Potential Clinical Relevance. Plastic and reconstructive surgery, 10.1097/PRS.0000000000010820.

Czumbel, L. M., Farkasdi, S., Gede, N., Mikó, A., Csupor, D., Lukács, A., Gaál, V., Kiss, S., Hegyi, P., & Varga, G. (2021). Hyaluronic Acid Is an Effective Dermal Filler for Lip Augmentation: A Meta-Analysis. Frontiers in surgery, 8, 681028.

Fakih-Gomez, N., & Kadouch, J. (2022). Combining Calcium Hydroxylapatite and Hyaluronic Acid Fillers for Aesthetic Indications: Efficacy of an Innovative Hybrid Filler. Aesthetic plastic surgery, 46(1), 373–381.

Gava, B., Suguihara, R. T., & Muknicka, D. P. (2023). Complications and intercurrences in lip filling with hyaluronic acid. Research, Society and Development, 12(5), e28412541900.

Graça, M. F. P., Miguel, S. P., Cabral, C. S. D., & Correia, I. J. (2020). Hyaluronic acid-Based wound dressings: A review. Carbohydrate polymers, 241, 116364.

Hilton, S., Frank, K., Alfertshofer, M., & Cotofana, S. (2023). Clinical outcomes after lip injection procedures-Comparison of two hyaluronic acid gel fillers with different product properties. Journal of cosmetic dermatology, 22(1), 119–127.

Juncan, A. M., Moisă, D. G., Santini, A., Morgovan, C., Rus, L. L., Vonica-Țincu, A. L., & Loghin, F. (2021). Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals. Molecules (Basel, Switzerland), 26(15), 4429.

Lopes, N. V., Suguihara, R. T., & Muknicka, D. P. (2023). The relationship between hyaluronic acid and COVID-19: a narrative review of the literature. Research, Society and Development, 12(8), e2612842869.

Machado, S. A. de S. L., & Muknicka, D. P. (2023). Benefits of hyaluronic acid in orofacial harmonization. Research, Society and Development, 12(8), e6912842894.

Marinho, A., Nunes, C., & Reis, S. (2021). Hyaluronic Acid: A Key Ingredient in the Therapy of Inflammation. Biomolecules, 11(10), 1518.

Papadopoulos T. (2020). Commentary on: Anatomy of the Superior and Inferior Labial Arteries Revised: An Ultrasound Investigation and Implication for Lip Volumization. Aesthetic surgery journal, 40(12), 1336–1340.

Ratajczak, P., Maciejak, O., Kopciuch, D., Paczkowska, A., Zaprutko, T., & Kus, K. (2023). Directions of hyaluronic acid application in cosmetology. Journal of cosmetic dermatology, 22(3), 862–871.

Ribé N. (2023). A technical approach for redefinition and volumization of lip area with hyaluronic acid: A case series. Journal of cosmetic dermatology, 22(6), 1739–1744.

Rother, E. T. (2007). Revisão sistemática x revisão narrativa. Acta Paul. Enferm, 20(2).

Safran, T., Swift, A., Cotofana, S., & Nikolis, A. (2021). Evaluating safety in hyaluronic acid lip injections. Expert opinion on drug safety, 20(12), 1473–1486.

Steenen, S. A., Bauland, C. G., van der Lei, B., Su, N., van Engelen, M. D. G., Anandbahadoer-Sitaldin, R. D. R. R. A. L., Koeiman, W., Jawidan, T., Hamraz, Y., & Lange, J. (2023). Head-to-head comparison of 4 hyaluronic acid dermal fillers for lip augmentation: A multicenter randomized, quadruple-blind, controlled clinical trial. Journal of the American Academy of Dermatology, 88(4), 932–935.

Stojanovič, L., & Majdič, N. (2019). Effectiveness and safety of hyaluronic acid fillers used to enhance overall lip fullness: A systematic review of clinical studies. Journal of cosmetic dermatology, 18(2), 436–443.

Tapsale, P., Türsen, B., & Türsen, Ü. (2022). Off label uses of hyaluronic acid fillers: A review. Dermatologic therapy, 35(11), e15876.

Walker, L., & Cetto, R. (2021). Lip Augmentation Using Hyaluronic Acid Filler and a 4-mm Needle: A Safer, More Natural, and Predictable Approach. The Journal of clinical and aesthetic dermatology, 14(1), E61–E63.

Published

10/11/2023

How to Cite

MATIOLLI , I. P. .; SUGUIHARA, R. T. .; MUKNICKA, D. P. . Adverse reactions of lip fillers with hyaluronic acid. Research, Society and Development, [S. l.], v. 12, n. 12, p. e23121243878, 2023. DOI: 10.33448/rsd-v12i12.43878. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/43878. Acesso em: 14 may. 2024.

Issue

Section

Health Sciences