Surgical treatment for odontogenic keratocyst and analysis of its imaging and histopathological characteristics: Case report

Authors

DOI:

https://doi.org/10.33448/rsd-v13i1.44863

Keywords:

Keratocysts; Odontogenic cysts; Pathology, oral.

Abstract

The Odontogenic Keratocyst (OK) is a lesion that affects the bones of the mandible and maxilla, of slow growth and asymptomatic. It originates from the odontogenic tissue by the proliferation of mesenchymal tissue, epithelial tissue, or both, with keratin production inside. OK treatment takes place in different stages and therapeutic approaches, therefore, the objective of this article is to describe, through a case report, the treatment performed for an OK from the completion of marsupialization, the surgical approach performed, and the two-year postoperative follow-up in a 15-year-old male patient. The lesion was radiolucent, unilocular, with a radiopaque halo, and anteroposterior growth without destruction of the cortical bone and the initial clinical approach consisted of performing an aspiration puncture and incisional biopsy whose histopathological analysis confirmed the diagnosis of OK. Therefore, marsupialization was performed with a cannula to stimulate the bone neoformation process and reduce the size of the lesion to be favorable to completely remove it, in addition to providing a safety margin to the adjacent noble structures. Six months after the decompression of the lesion, the patient underwent surgical enucleation of the lesion associated with peripheral osteotomy. The radiographic aspect, 2 years after the surgery, shows locais bone neoformation, the integrity of noble structures such as the mandibular canal, and no evidence of lesion recurrence. The patient will be followed up for another 3 years, every 6 months.

Author Biography

Félix Augusto Figueiredo Neto , Faculdade Arnaldo Janssen

 

 

References

Al-Moraissi, E. A. & Dahan, A. A. & Alwadeai, M. S. et al (2017). What surgical treatment has the lowest recurrence rate following the management of keratocystic odontogenic tumor? A large systematic review and meta-analysis. J Cranio-Maxillo-Fac Surg, 45(1):131-144.

Boffano, P. & Ruga, E. & Gallesio, C. (2010) Keratocystic odontogenic tumor (odontogenic keratocyst): preliminary retrospective review of epidemiologic, clinical, and radiologic features of 261 lesions from University of Turin. J Oral Maxillofac Surg, 68(12), 2994–2999.

Castro, J. (2016). Decompression of odontogenic cystic lesions: past, present, and future. J Oral MaxillofacSurg,74(1), 104.

Chrcanovic, B. R. & Gomez, R. S. (2017). Recurrence probability for keratocystic odontogenic tumors: An analysis of 6427 cases. Journal of Cranio-Maxillofacial Surgery, 45(2), 244–251.

Cunha, J. F. & Gomes, C. C. & Mesquita, R. A, et al (2016). Clinicopathologic features associated with recurrence of the odontogenic keratocyst: a cohort retrospective analysis. Oral Surg Oral Med Oral Pathol Oral Radiol, 121(6), 629–635.

Li, T-J. (2011). The Odontogenic Keratocyst: A Cyst, or a Cystic Neoplasm? Journal of Dental Research, 90(2), 133-142.

Marques, D. H. & Barros, M. A. N. & Teslenco, V. B. & Santana Junior, G. N. dos (2020). Tratamento cirúrgico do ceratocisto odontogênico por meio de enucleação e osteotomia periférica: relato de caso. Archives of Health Investigation, 9(6), 531–534.

Marques, J. A. F. et al (2013). Ceratocisto odontogênico: relato de caso. Sitientibus, 64.

Oliveira, M. M. et al (2013). Tratamento de tumor odontogênico queratocístico. Archives of health investigation, 2(5).

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. UFSM.

Pylkkö, J., et al. (2023). Appearance and recurrence of odontogenic keratocysts. Clin Exp Dent Res. 9(5):894-898.

Ramos, E. A. A. & Alves, F. A. M. & Lascala, C. A. et al (2018). Efficacy of MRI in the differential diagnosis of odontogenic keratocyst: literature review. Clin Lab Res Den, 1, 1-10.

Rios, Y. C. G. & Monteiro, M. A. O. (2021). Marsupialização de ceratocisto: relato de caso [Manuscrito não publicado]. Curso de Odontologia, Faculdade Arnaldo.

Santoash, A (2020). Odontogenic Cysts. Dental Clinics of North America, 64(1), 110-111.

Silva, L. B. A. (2019). Análise comparativa das características clínicas, radiográficas e histológicas de ceratocistos odontogênicos. BS thesis, 31.

Stresser, F. & Cunico, L. & Schespanski, N. (2020). Cistos e Tumores Odontogênicos. Acervo Digital da UFPR.

Valdivia A. D. & Ramos-Ibarra M. L. & Franco-Barrera M. J. et al. (2022) What is currently known about odontogenic keratocysts?. Oral Health Prev Dent., 20: 321-330.

Published

26/01/2024

How to Cite

FIGUEIREDO NETO , F. A. .; SILVA , A. J. C. de O. .; SOUTO, E. M. M. da C. .; PEREIRA, M. J. C. .; SOARES, B. M.; GRANDINETTI, H. de A. M. .; CASTRO, C. H. B. C. de .; RESENDE, R. G. Surgical treatment for odontogenic keratocyst and analysis of its imaging and histopathological characteristics: Case report . Research, Society and Development, [S. l.], v. 13, n. 1, p. e11813144863, 2024. DOI: 10.33448/rsd-v13i1.44863. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/44863. Acesso em: 14 may. 2024.

Issue

Section

Health Sciences