Treatment Possibilities in Incisive Molar Hypomineralization (HMI)
DOI:
https://doi.org/10.33448/rsd-v13i2.44922Keywords:
Desmineralization; Molar hypomineralization; Pediatric dentistry.Abstract
Molar Incisive Hypomineralization (HMI) is a defect in the development of enamel of systemic origin, there is a disharmony in enamel-forming cells, during prenatal, natal or postnatal, resulting in demineralization of tooth enamel. The proposed treatments vary and go according to the degree and location of the HMI, and may be aimed at prevention, rehabilitation and even the extraction of the dental element. The objective of this study is to describe the possibilities of treatments available for HMI, assisting the dental surgeon in deciding the treatment indicated for each degree of HMI, through a literature review. An integrative literature review was performed through articles selected through queries to the Google Scholar and National Library of Medicine (PubMed) databases, using 16 articles, published in Portuguese and English, which demonstrated the possibilities of treatments available in cases of HMI. According to studies carried out in this research, eighteen different methods were observed that can be used for treatment in patients with HMI, the most used methods were: desensitizing and remineralizing agents, fluoride varnish, ionomeric sealants, resinous sealants, restorations with composite resin, microabrasion and tooth extraction. The treatments available range from prevention and control of the diet, to tooth extraction, in severe cases where there is no possibility of treatment. It is necessary the periodic follow-up of patients with HMI, so the professional will provide a better quality of life to patients affected by this condition.
References
Alencar, C. R. B. & Cavalcanti, A. L. (2018). Molar incisor hypomineralization - A challenge of Pediatric Dentistry? J Oral Res. 7(3), 84-5. 10.17126/joralres.2018.026.
Almulhim, B. (2021). Molar and Incisor Hypomineralization. Nepal Med Assoc. 59 (235): 295-302. 10.31729/jnma.6343.
Alves, M. C. O., Camargos, B. S. F., Carvalho, T. A. & Machado, F. C. (2021). Protocolos clínicos em Hipomineralização Molar Incisivo (HMI): revisão integrativa da literatura. Research, Society and Development. 10(13). http://dx.doi.org/10.33448/rsd-v10i13.21605.
Assunção, C. M., Girelli, V., Sarti, C. S., Ferreira, E. S., Araujo, F. B. & Rodrigues, J. A. (2014). Hipomineralização de molar-incisivo (HMI): relato de caso e acompanhamento de tratamento restaurador. Revista da Associacao Paulista de Cirurgioes Dentistas. 68 (4): 346-350.
Bekes, K., Heinzelmann, K., Lettner, S. & Schaller, H. G. (2016). Efficacy of desensitizing products containing 8% arginine and calcium carbonate for hypersensitivity relief in MIH affected molars: an 8 week clinical study. Clin Oral Investig. 21(7), 2311-2317.
Bezamat, M., Souza, J. F., Silva, F., Corrêa, E. G., Fatturi, A. L., Brancher, J. A., Carvalho, F. M., Cavallari, T., Bertolazo, L., Machado-Souza, C., Koruyucu, M., Bayram, M., Racic, A., Harrison, B. M., Sweat, Y. Y., Letra, A., Studen-Pavlovich, D., Seymen, F., Amendt, B., Werneck, R. I., & Vieira, A. R. (2021). Gene-environment interaction in molar-incisor hypomineralization. PloS one. 16(1). https://doi.org/10.1371/journal.pone.0241898.
Borges, A. B., Caneppele, T. M. F., Masterson D. & Maia, L. C. (2017). Is resin infiltration an effective esthetic treatment for enamel development defects and white spot lesions? A systematic review. J Dent. 56, 11–18.
Borsatto, T. V. F. S. & Fernandes, M. L. M. F. (2022). Hipomineralização molar-incisivo (HMI): diagnóstico diferencial entre outras hipomineralizações. Brazilian Journal of Health Review. Curitiba. 5(3), 11874-11883. 10.34119/bjhrv5n3-319.
Clarkson, J. (1992). A review of the developmental defects of enamel index (DDE). Int. Dent. J. London. 42(5), 411-426.
Coelho, A. S. E. C., Mata, P. C. M., Lino, C. A., Macho, V. M. P., Areias, C. M. F. G. P., Norton, A. P. M. A. P. & Augusto, A. P. C. M. (2019). Dental hypomineralization treatment: A systematic review. J Esthet Restor Dent. 1–14. 10.1111/jerd.12420.
Cunha, L. S., Lima, C. C., Braga, L. L. A., Andrade, C. M. O., Caixeta, D. A. F. & Dietrich, L. (2020). Hipomineralização Molar-Incisivo em dentes permanentes: revisão de literatura. Research, Society and Development. 9(11), 1-16. http://dx.doi.org/10.33448/rsd-v9i11.9653.
Daly. D. & Waldron, J. M. (2009). Molar incisor hypomineralisation: clinical management of the young patient. J of the Irish Dental Association. 55 (2): 83-6.
Dhareula, A., Goyal, A., Gauba, K. & Bhatia, S. K. (2018). Esthetic rehabilitation of first permanent molars affected with severe form of Molar Incisor Hypomineralization using indirect composite onlays-A case series. Pediatr. Dent. J. Tokyo. 28(2), 62-67.
Domingos, P. A. S., Ricci-Donato, H. A., Nonato, C. N., Souza, E. O. & Silva. V. J. (2019). Hipomineralização molar incisivo: revisão de literatura. Journal of Research in Dentistry. 7(2), 7-12.
Elfrink, M. E. C., Cate, J. M., Jaddoe, V. W. V., Hofman, U., Moll, H. A. & Veerkamp, J. S. J. (2012). Deciduous molar hypomineralization and molar incisor hypomineralization. J. Dent. Res. 91(6), 551-555.
Eller, J. C. M. S., Wanssa, N., Bianco, K. G. S. B. & Salomão-Miranda, F. (2021). Hipomineralização Molar Incisivo: Desafios Clínicos e Tratamento em Odontopediatria. Revista FIMCA. 8(1), 47-50. https://doi.org/10.37157/fimca.v8i1.231.
Farias, L., Laureano, I. C. C., Alencar, C. R. B. & Cavalcanti, A. L. (2018). Hipomineralização molar incisivo: etiologia, características clínicas e tratamento. Revista de Ciências Médicas e Biológicas. 17(2), 211- 219. http://dx.doi.org/10.9771/cmbio.v17i2.27435.
Fayle, S. A. (2003). Molar incisor hypomineralisation: restorative management. Eur J Paediatr Dent. 2, 121–6.
Fernandes, A. S., Mesquita, P. & Vinhas, L. (2012). Hipomineralização incisivo molar: Uma revisão de literatura. Revista Portuguesa de Estomatologia,
Medicina Dentária e Cirurgia Maxilofacial. 53(4), 258-262.
Fitzpatrick, L. & O’Connell, A. (2007) First permanent molars with molar incisor hypomineralisation. J Ir Dent Assoc. 53, 32-7.
Folayan, M. O., Chukwumah, N. M., Popoola, B. O. et al. (2018). Developmental defects of the enamel and its impact on the oral health quality of life of children resident in Southwest Nigeria. BMC Oral Health. 18. 160. https://doi.org/10.1186/s12903-018-0622-3.
Fragelli, C. M. B., Jeremias, F., Souza, J. F., Paschoal, M. A., Cordeiro, R. C. L. & Santos-Pinto, L. (2015). Longitudinal evaluation of the structural integrity of teeth affected by molar incisor hypomineralisation. Caries Res. 49(4), 378-83.
Fragelli, C. M. B., Souza, J. F., Bussaneli, D. G., Jeremias F., Santos-Pinto, L. D. & Cordeiro, R. C. L. (2017). Survival of sealants in molars affected by molar-incisor hypomineralization: 18-month follw-up. Braz Oral Res. 31(1), 1-9.
Garot, E., Denis, A., Delbos, Y., Manton, D., Silva, M. & Rouas, P. (2018). Are hypomineralised lesions on second primary molars (HSPM) a predictive sign of molar incisor hypomineralisation (MIH)? A systematic review and a meta-analysis. J Dent. 72, 8-13. 10.1016/j.jdent.2018.03.005.
Giannetti, L., Diago, A. M. D, Corciolani, E. & Spinas, E. (2018). Deep infiltration for the treatment of hypomineralized enamel lesions in a patient with molar incisor hypomineralization: a clinical case. J Biol Regul Homeost Agent. 32(3), 751-4.
Goursand, D., Souza, F. B., Fontes, F. S., Oliveira, G., Lima, L. S. & Sales, N. A. F. (2023). Conhecendo a hipomineralização molar-incisivo: do diagnóstico ao tratamento. Brazilian Journal of Health Review. 1(6), 1016-1024. 10.34119/bjhrv6n1-079.
Guergolette, R. P., Dezan, C. C., Frossard, W. T. G., Ferreira, F. B. A., Cerci, A. Neto. & Fernandes, K. B. P. (2009). Prevalence of developmental defects of enamel in children and adolescents with asthma. J. Bras. Pneumol. Brasília. 35 (9), 295-300.
Harika, R., Dutta, B., Arun, P. & Teja, R. P. (2016). A novel clinical approach for long-term retention and durability of resin restorations bonded to multiple developmental defects of enamel. J. Int. Soc. Prev. Community Dent. Mumbai. 6(6), 597-601.
Hubbard, M. J, Mangum, J. E., Perez, V.A., Nervo, G. J. & Hall, R. K. (2017). Molar Hypomineralisation: A Call to Arms for Enamel Researchers. Front Physiol. 8: 546. 10.3389/fphys.2017.00546.
Jeremias, F., Silva, C. M. C., Souza, J. F., Zuanon, A. C. C., Cordeiro, R. C. L. & Santos, P. L. (2010). Hipomineralización de incisivos y molares: aspectos clínicos de La severidad. Acta Odontológica Venezolana. 48, 1-9.
Lagarde, M., Vennat, E., Attal, P. J. & Dursun, E. (2020). Strategies to optimize bonding of adhesive materials to molarincisor hypomineralization-affected enamel: A systematic review. Int J Paediatr Dent. 30, 405–420. 10.1111/ipd.12621.
Lopes, L. B., Machado, V. Botelho, J. & Haubek, D. (2021). Molar-incisor hypomineralization: an umbrella review. Acta Odontologica Scandinavica. https://doi.org/10.1080/00016357.2020.1863461.
Lygidakis, N. A. (2010). Treatment modalities in children with teeth affected by molar-incisor enamel hypomineralisation (MIH), A systematic review. Eur Arch Paediatr Dent. 11 (2), 65-74.
Lygidakis, N. A., Wong, F., Jälevik, B., Vierrou, A.M., Alaluusua, S. & Espelid, I. (2010) Best Clinical Practice Guidance for clinicians dealing with children presenting with Molar-Incisor-Hypomineralisation (MIH), An EAPD Policy Document. Eur Arch Paediatr Dent. 11, 75-81.
Machado, A. C., Maximiano, V., Eduardo, C. P., Azevedo, L. H., de Freitas, P. M. & Aranha, A. C. (2019). Associative Protocol for Dentin Hypersensitivity Using Nd:YAG Laser and Desensitizing Agent in Teeth with Molar-Incisor Hypomineralization. Photobiomodulation, Photomedicine, and Laser Surgery. 37 (4), 262–266.
Martins, M. R. S., Silva, I. L. I. & Abrantes, R. M. (2021). Hipomineralização molar-incisivo: a importância do diagnóstico diferencial para instituir um tratamento adequado aos pacientes afetados por esta condição. Research, Society and Development. 10(10). http://dx.doi.org/10.33448/rsd-v10i10.18801.
Muniz, R. S. C., Ferreira, M. C. & Carvalho, C. N. (2019). Eficácia da terapia com laser de baixa intensidade associada à terapia com flúor para a dessensibilização da hipomineralização molar-incisivo: ensaio clínico randomizado. Universidade CEUMA.
Onat, H. & Tosun, G. (2013). Molar incisor hypomineralization. Journal of Pediatric Dentistry. 1(3), 53-57.
Padavala, S. & Sukumaran, G. (2018). Molar Incisor Hypomineralization and Its Prevalence. Contemp Clin Dent. 9(2), S246–S250. 10.4103/ccd.ccd_161_18.
Pasini, M., Giuca, M. R., Scatena, M., Gatto, R. & Caruso, S. (2018). Molar incisivo hipomineralização tratamento com fosfopeptídeo de caseína e fosfato de cálcio amorfo em crianças. Minerva Stomatol. 67, 20-5.
Pereira, M. S. S., Rodrigues, H. S. G., Marques, N. C. T., Almada, K. C., Oliveira, L. D. & Bruzadelli, P. B. (2021). Hipomineralização Molar-Incisivo: Um desafio na rotina da Odontopediatria do século XXI. RvAcBO. 10(2), 80-86.
Rao, M. H., Aluru, S. C., Jayam. C., Bandlapalli, A. & Patel, N. (2016). Molar Incisor Hypomineralization. Contemp Dent Pract. 17(7), 609-13.
Resende, P. F. & Favretto, C. O. (2019). Desafios clínicos no tratamento de hipomineralização molar incisivo. Journal of Oral Investigations. 8(2), 73-83. https://doi.org/10.18256/2238-510X.2019.v8i2.3119.
Silva, A. R. S., Moraes, G. M., Guedes, P. F., Koga, R. S. & Carlos, A. M. P. (2020). Tratamento de hipomineralização molar – incisivo em odontopediatria: revisão de literatura. Brazilian Journal of health Review. 3(6), 16789-16801. 10.34119/bjhrv3n6-093.
Silva, G. P., Jr., Souza, L. M. A. & Groppo, F. C. (2017). Comparison of articaine and lidocaine for buccal infiltration after inferior alveolar nerve block for intraoperative pain control during impacted mandibular third molar surgery. Anesth Prog. 64(2),80-4.
Silva, I. F., Jr., Oliveira, C. R., Berwig, P. S. & Schardosim, L. S. (2018). Reabilitação de dentes afetados pela hipomineralização molar-incisivo (HMI), Um relato de caso com 16 meses de acompanhamento. Revista da Faculdade de Odontologia – UPF. 23(2), 218-224.
Silva, T. A., Melo, I. A., Silva, T. A., Maurício, S. C. M., Sousa, A. A., Fragoso, L. S. M., Romão, D. A. & Porto, I. C. C. M. (2020). Importância do Diagnóstico Precoce de Hipomineralização Molar-incisivo (HMI), Revisão de Literatura. Brazilian Journal of Development. 6(11), 85239-85247. 10.34117/bjdv6n11-079.
Seow, W. K. (2014). Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust. Dent. J. Sydney. 1 (S1), 143-154.
Souza, J. F., Fragelli, C. B., Jeremias, F., Paschoal, M. A. B., Santos-Pinto, L. & Cordeiro, R. C. L. (2017). Eighteen-month clinical performance of composite resin restorations with two different adhesive systems for molars affected by molar incisor hypomineralization. Clin Oral Investig. 21(5), 1725-1733.
Souza, M. T., Silva, M. D., & Carvalho, R. (2010). Revisão integrativa: o que é e como fazer. Einstein. (São Paulo). 8(1), 102-106
.
Stenhagen, K. & Tveit, A. (2016) Microabrasion to improve aesthetic. Vidensk Klin. 26(120), 890-7.
Subramaniam, P., Gupta, T. & Sharma, A. (2016). Prevalence of molar incisor hypomineralization in 7–9-year-old children of Bengaluru City, India. Contemp. Clin. Dent. 7 (1), 11-15.
Tomo, S., Boer, N. P., Fortunato, J. B. & Cunha-Correia, A. S. (2016). Molar-incisor hypomineralization (MIH), report of a severe case. Revista Odontologia Universidade Cidade de São Paulo. 28(1), 58-64.
Vilani, P. N. L., Paim, A. S., Penido, C. V. S. R. & Barra, S. G. (2014). Hipomineralização molar-incisivo: relato de caso clínico. Faculdade de Odontologia de Lins/Unimep. 24(1), 64-68.
Weerheijm, K. L. (2004). Molar incisor hypomineralization (MIH), clinical presentation aetiology and management. Dental Update. 31 (1), 9-12. 10.5005/jp-journals-10005-1164.
Weerheijm, K. L., Jalevik, B. & Alaluusua, S. (2001). Molar incisor hypomineralisation. Caries Research. 35(5), 390-391.
Weerheijm, K. L. & Mejàre, I. (2003). Molar incisor hypomineralization: a questionnaire inventory of its occurrence in member countries of the European Academy of Paediatric Dentistry (EAPD). Int J Paediatr Dent. 13: 411-6.
Willmontt, N. S. (2008). Molar-Incisor-Hypomineralization: a literature review. Eur Arch Paediatr Dent. 9, 172-9.
Willmott, N. S., Bryan, R. A. E. & Duggal, M. S. (2008). Molar-Incisor-Hypomineralization: a literature review. Eur Arch Paediatr Dent. 9(4), 172-179.
Yannam, S. D., Amarlal, D. & Rekha, C. V. (2016). Prevalence of molar incisor hypomineralization in school children aged 8-12 years in Chennai. J. Indian. Soc. Pedod. Prev. Dent. 34(2), 134-138.
Zanatta, R. A., Feres, V. E. R. & Duarte, D. A. (2019) Lesões não cariosas e HMI. Napoleão.
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