Overview of scientific publications (2019-2023) on Gastrointestinal Inflammation associated with Orlistat: An integrative review of the literature

Authors

DOI:

https://doi.org/10.33448/rsd-v13i2.44969

Keywords:

Orlistat; Gastroenterology; Gastrointestinal inflammation; Integrative review; Adverse effects.

Abstract

Objective: To conduct an integrative literature review to assess the role of Orlistat in inducing gastrointestinal inflammation, identify the underlying mechanisms, and provide a comprehensive overview of existing studies on the subject from 2019 to 2023. Method: Follows an integrative review approach, aiming to aggregate the results of published research and present them from a research question. Searches were conducted in various databases, including MEDLINE (via the PubMed portal of the National Library of Medicine), LILACS (Latin American and Caribbean Literature in Health Sciences), EMBASE, SCOPUS, and Web of Science. Results: 11 publications were selected for inclusion in the study. This relatively small number of included studies, compared to the initial number (195) of identified publications, reflects the rigor of the selection criteria and the emphasis on the quality and relevance of the data. Regarding the categories, Inflammation Biomarkers, Involved Mediators, Effects at Different Doses, and Impact of Treatment Duration were identified. Conclusion: It is concluded that the personalization of treatment, considering individual characteristics and patient response, is essential to maximize benefits and minimize adverse effects.

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Published

14/02/2024

How to Cite

SILVA, K. L. S. .; REDIG, C. B. .; FURTADO, G. E. M. .; SCHEFFER, G. A. .; FERREIRA, E. O. .; DINIZ, . I. G. .; GUIMARÃES, M. C. M. . Overview of scientific publications (2019-2023) on Gastrointestinal Inflammation associated with Orlistat: An integrative review of the literature. Research, Society and Development, [S. l.], v. 13, n. 2, p. e5113244969, 2024. DOI: 10.33448/rsd-v13i2.44969. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/44969. Acesso em: 11 may. 2024.

Issue

Vol. 13 No. 2

Section

Health Sciences

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Copyright (c) 2024 Kamila Luana Santos Silva; Carolina Barbosa Redig; Giovanna Eduarda Mauro Furtado; Glaucya Abdalla Scheffer; Eduarda Oliveira Ferreira; Isabela Guerreiro Diniz; Márcia Cristina Monteiro Guimarães

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