Sporothrix schenckii complex in felines: Analysis of clinical, mycological, environmental and epidemiological factors

Authors

DOI:

https://doi.org/10.33448/rsd-v13i2.45056

Keywords:

Fungi; Mycology; Sporotrichosis; Veterinary medicine; Zoonoses.

Abstract

Sporotrichosis is an infectious and chronic fungal disease caused by fungi belonging to the Sporothrix schenckii complex that affects humans and animals through traumatic implantation of the fungus in the skin. They are dimorphic, saprophytic and geophilic fungi that are widely distributed in nature, especially in soils rich in organic matter. The aim of this study was to understand the clinical, mycological, environmental and epidemiological aspects of the Sporothrix schenckii complex in felines. In order to meet the objectives of this research, a qualitative, descriptive and exploratory data survey was carried out through a bibliographic review based on works published in the last 23 years. Sporothrix spp. is considered to be a complex of at least six cryptic species, in other words, they have similar morphological characteristics but different genotypes. In cats, the incubation period is variable; it usually lasts 14 days. On penetrating the tissue, the micellar form transforms into yeast, which generates an inflammatory response and proliferation of the microorganism at the site, causing papular and nodular lesions which, in some cases, heal spontaneously. Therefore, it is clear that sporotrichosis is caused by dimorphic fungi of the Sporothrix schenkii complex. It is a zoonotic disease of great importance in the context of public health, since it is still a neglected disease and requires robust measures to control. As well as being the most seriously affected, felines are the main transmitters to humans and animals, making them a key point in controlling outbreaks of the disease.

Author Biography

Rubens Barbosa Rezende, Federal University of São Paulo

Graduated in Biomedicine (UNIFASAR - 2017/2021), with qualifications in Clinical Pathology, Imaging, Oncotic Cytology, Immunology and Hematology. Specialist in Clinical Immunology, Hematology and Oncotic Cytology at UniBF College; Imaging and Veterinary Mycology at Unyleya College; Biotechnology at UNIFESP and Clinical and Laboratory Microbiology at the Academy of Science and Technology. PhD student in Postgraduate Program in Public Health of the Christian Business School (Florida/USA).

References

Andrade, E. H. P. et al. (2021). Characterization of animal sporotrichosis in a highly urbanized area. Comparative Immunology, Microbiology and Infectious Diseases, 76, 101651.

Antunes, T. A. et al. (2009). Esporotricose cutânea experimental: avaliação in vivo do itraconazol e terbinafina. Rev. Soc. Bra. Med. Trop., 42:23.

Brandolt, T. M. et al. (2019). Human sporotrichosis: A zoonotic outbreak in southern Brazil, 2012–2017. Medical Mycology, 57(5).

Caus, A. L. O. et al. (2019). Epidemiological and clinical aspects of sporotrichosis in Espírito Santo State, southeast Brazil: A study of three decades (1982–2012). American Journal of Tropical Medicine and Hygiene, 100(3):706–713.

Chakrabarti, A. et al. (2015). Global epidemiology of sporotrichosis. Medical mycology, 53(1), 3–14.

Cruz, L. C. H. (2013). Complexo Sporothrix schenckii. Revisão de parte da literatura e considerações sobre o diagnóstico e a epidemiologia. Vet e Zootec., 20:08- 28.

De beer, Z. W., Duong, T. A., & Wingfield, M. J. (2016). The divorce of Sporothrix and Ophiostoma: Solution to a problematic relationship. Studies in Mycology, 83(1907):165–191.

Falcão, E. M. M. et al. (2019). Hospitalizações e óbitos relacionados à esporotricose no Brasil (1992-2015). Cadernos de Saúde Pública, 35(4):e00109218.

Freitas. D. F. S. (2014). Avaliação de fatores epidemiológicos, micológicos, clínicos e terapêuticos associados à esporotricose. Rio de Janeiro. Tese [Doutorado em Medicina] - Instituto Oswaldo Cruz.

Gil, A. C. (2002). Como elaborar projetos de pesquisa. (4a ed.), Atlas.

Godoy, A. S. (1995). Introdução à pesquisa qualitativa e suas possibilidades. Revista de Administração de Empresas, 35(2), 57-63.

Greene, C. E. (2006). Infectious diseases of the dog and cat. [s.l.] WB SaundersElsevier Science.

Gremião, I. D. F. et al. (2020). Geographic Expansion of Sporotrichosis, Brazil. Emerging Infectious Diseases, 26(3), 621–624.

Gremião, I. D. F. et al. (2021). Guideline for the management of feline sporotrichosis caused by Sporothrix brasiliensis and literature revision Brazilian Journal of Veterinary Research and Animal Science, 52(1):107–124.

Gremião, I. D. F. et al. (2017). Zoonotic Epidemic of Sporotrichosis: Cat to Human Transmission. PLoS Pathogens, 13(1).

Guarro, J., Gené, J., & Stchigel, A. M. (1999). Developments in fungal taxonomy. Clin Microbiol Ver. 12, 454-500.

Gusmão, B. S. (2017). Esporotricose felina, uma doença emergente de risco a saúde pública: Aspectos clínicos-epidemiológicos. Rev. Cien. Med. Vet., 28, 1-7.

Jackson, H. A. & Marsella, R. (2012). BSAVA manual of canine and feline dermatology. [s.l.] British Small Animal Veterinary Association.

Jericó, M. M., Andrade Neto, J. P., & Kogika, M. M. (2015.) Tratado de medicina interna de cães e gatos.

Kwon-Chung, K. J. & Bennett, J. E. (1992). Medical Mycology. (2nd ed.) Lea & Febiger, 707-29.

Lacaz, C. S. (2002). Esporotricose e outras micoses gomosas. In: Lacaz CS, Porto E, Martins JEC, Heins-vaccari EM, Melo NT. Tratado de Micologia Médica Lacaz. (9a ed.), Sarvier, 479-97.

Larsson, C. E. (2011). Esporotricose. Brazilian Journal of Veterinary Research and Animal Science, 48(3), 250.

Lecca, L. O. et al. (2020). Associated factors and spatial patterns of the epidemic sporotrichosis in a high density human populated area: A cross-sectional study from 2016 to 2018. Preventive Veterinary Medicine, 176:104939.

Lopes-Bezerra, L. M., Schubach, A., & Costa, R. O. (2006). Sporothrix schenckii and sporotrichosis. An. Acad. Bras. Ciênc., 78(2), 293-308.

López-Romero, E. et al. (2011). Sporothrix schenckii complex and sporotrichosis, an emerging healthproblem. Future Microbiology, 6(1), 85–102.

Marimon, R. et al. (2007). Sporothrix brasiliensis, S. globosa, and S. mexicana, three new Sporothrix species of clinical interest. J Clin Microbiol. 45, 3198-206.

Mcvey, D. S., Kennedy, M., & Chengappa, M. (2016). Microbiologia veterinaria. [s.l.] Grupo Gen-Guanabara Koogan.

Megid, J., Ribeiro, M. G., & Paes, A. C. (2016). Doenças infecciosas em animais de produção e de companhia. Roca, 799–821.

Orofino-Costa, R., et al. (2017). Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics. An. Bras. Dermatol., 92(5):606-620.

Paiva, M. T. et al. (2020). Spatial association between sporotrichosis in cats and in human during a Brazilian epidemics. Preventive Veterinary Medicine, 105125.

Penha, C. V. & Bezerra, L. M. (2000). Concanavalin A-binding cell wall antigens of Sporothrix schenckii: a serological study. Med Mycol. 38, 1-7.

Pereira, A. S., et al. (2018). Metodologia da pesquisa científica. UFSM. 2018. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1 Accessed in: October 20, 2023.

Podestá Junior, R. L. de, et al. (2022). Feline sporotrichosis: Clinical conduct, diagnosis and treatment recommended in the municipality of Vitória- ES. Research, Society and Development, 11(10), e589111031028. https://doi.org/10.33448/rsd-v11i10.31028

Ramírez-Soto, M. et al. (2018). Ecological Determinants of Sporotrichosis Etiological Agents. Journal of Fungi, 4(3), 95.

Rangel-Gamboa, L. et al. (2016). Update of phylogenetic and genetic diversity of Sporothrix schenckii sensu lato. Medical Mycology, 54(3), 248–255.

Rippon, J. W. (1988). Medical Mycology: the pathogenic fungi and the pathogenic actinomycetes. 3rd ed. Philadelphia: WB Saunders, 325-52.

Rodrigues, A. M. et al. (2020). The threat of emerging and re-emerging pathogenic Sporothrix species. Mycopathologia, 185(5), 813–842.

Rojas, O. C. et al. (2018). Molecular identification, antifungal susceptibility, and geographic origin of clinical strains of Sporothrix schenckii complex in Mexico. Journal of Fungi, 4(3).

Sales, A. L. G. (2021). Epidemiologia da esporotricose animal e humana no município de Salvador - BA/ Ana Lúcia Galvão Sales. Salvador, 2021. Dissertação (Mestrado em Biotecnologia em Saúde e Medicina Investigativa) – Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador.

Santos, A. F. et al. (2018). Guia prático para enfrentamento da esporotricose felina em Minas Gerais. Revista Veterinária & Zootecnia em Minas, 137(38), 16–27.

Schubach, T. M. P. et al. (2004). Evaluation of an epidemic of sporotrichosis in cats: 347 cases (1998–2001). Journal of the American Veterinary Medical Association, 224(10):1623–1629.

St-Germain, G. & Summerbell, R. (1996) Identifying filamentous fungi. In: A clinical laboratory handbook. California: Star Publishing Company.

Triviños, A. N. S. (1987) Introdução à pesquisa em ciências sociais: a pesquisa qualitativa em educação. Atlas, 100.

Zancopé-Oliveira, R. M., et al. (2011) New diagnostic applications in sporotrichosis. In: Khopkar U, editor. Skin biopsy perspectives. Rijeka: In Tech, 53-72.

Zhang, Y. et al. Phylogeography and evolutionary patterns in Sporothrix spanning more than 14 000 human and animal case reports. (2015). Persoonia: Molecular Phylogeny and Evolution of Fungi, 35(1).

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Published

17/02/2024

How to Cite

REZENDE, R. B. Sporothrix schenckii complex in felines: Analysis of clinical, mycological, environmental and epidemiological factors. Research, Society and Development, [S. l.], v. 13, n. 2, p. e6713245056, 2024. DOI: 10.33448/rsd-v13i2.45056. Disponível em: https://www.rsdjournal.org/index.php/rsd/article/view/45056. Acesso em: 12 may. 2024.

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Section

Review Article