Characterization of pain in patients with Parkinson’s disease: a descriptive cross-sectional study
DOI:
https://doi.org/10.33448/rsd-v9i10.9057Keywords:
Quality of life; Neurodegenerative disease; Palliative treatment; Visual Analog Scale; Wisconsin brief pain inventory.Abstract
Parkinson's disease affects the central nervous system, causing dysfunctional dopamine production. This directly affects the motor system, leading to the loss of voluntary movements, joint stiffness, limb tremors, and imbalance. Palliative treatments are applied to alleviate symptoms of the disease and improve quality of life. Considering functional changes and symptoms that are generated by Parkinson's disease, pain is also a debilitating factor that can severely affect the individual. The present study investigated the mean age, duration of involvement, body locus incidence, and interference with quality of life by pain in patients with Parkinson's disease. We applied a one-dimensional, subjective, and qualitative Visual Analog Scale and the multidimensional and interpretative Wisconsin Brief Pain Inventory. The study was conducted with 36 participants of both genders (mean age: 65.5 years for men and 72.0 years for women). The incidence of pain was detected in 87.5% of the participants. We found that pain occurred more frequently in the upper limbs and interfered with the performance of general activities. Treatment by a multidisciplinary team in all dimensions of the disease is needed to alleviate patients’ pain and consequently improve their quality of life.
References
Alexander, G. E. (2004). Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder. Dialogues in clinical neuroscience, 6(3), 259.
Allen, N. E., Moloney, N., Van Vliet, V., & Canning, C. G. (2015). The rationale for exercise in the management of pain in Parkinson’s disease. Journal of Parkinson's disease, 5(2), 229-239. DOI: https://doi.org/10.3233/JPD-140508
Atkinson, T. M., Mendoza, T. R., Sit, L., Passik, S., Scher, H. I., Cleeland, C., & Basch, E. (2010). The Brief Pain Inventory and its “pain at its worst in the last 24 hours” item: clinical trial endpoint considerations. Pain Medicine, 11(3), 337-346. DOI: https://doi.org/10.1111/j.1526-4637.2009.00774.x
Beiske, A. G., Loge, J. H., Rønningen, A., & Svensson, E. (2009). Pain in Parkinson’s disease: prevalence and characteristics. Pain, 141(1-2), 173-177. DOI: https://doi.org/10.1016/j.pain.2008.12.004
Bhalsing, K. S., Abbas, M. M., & Tan, L. C. (2018). Role of physical activity in Parkinson's disease. Annals of Indian Academy of Neurology, 21(4), 242. DOI: https://dx.doi.org/10.4103%2Faian.AIAN_169_18
Bloem, B. R., VAN VUGT, J. P., & Beckley, D. J. (2001). Postural instability and falls in Parkinson's disease. Advances in neurology, 87, 209-223.
Broen, M. P., Braaksma, M. M., Patijn, J., & Weber, W. E. (2012). Prevalence of pain in Parkinson's disease: a systematic review using the modified QUADAS tool. Movement Disorders, 27(4), 480-484. DOI: https://doi.org/10.1002/mds.24054
Buhmann, C., Wrobel, N., Grashorn, W., Fruendt, O., Wesemann, K., Diedrich, S., & Bingel, U. (2017). Pain in Parkinson disease: a cross-sectional survey of its prevalence, specifics, and therapy. Journal of neurology, 264(4), 758-769. DOI: https://doi.org/10.1007/s00415-017-8426-y
Ferraz, D. D., Trippo, K. V., Duarte, G. P., Neto, M. G., Santos, K. O. B., & Oliveira Filho, J. (2018). The effects of functional training, bicycle exercise, and exergaming on walking capacity of elderly patients with Parkinson disease: a pilot randomized controlled single-blinded trial. Archives of physical medicine and rehabilitation, 99(5), 826-833. DOI: https://doi.org/10.1016/j.apmr.2017.12.014
Ferreira, K.A., Teixeira, M.J., Mendonza, T.R., Cleeland, C.S. (2011). Validation of brief pain inventory to Brazilian patients with pain. Support Care Cancer, 19, 505-511.
Gallagher, E. J., Liebman, M., & Bijur, P. E. (2001). Prospective validation of clinically important changes in pain severity measured on a visual analog scale. Annals of emergency medicine, 38(6), 633-638. DOI: https://doi.org/10.1067/mem.2001.118863
George, J. L., Mok, S., Moses, D., Wilkins, S., Bush, A. I., Cherny, R. A., & Finkelstein, D. I. (2009). Targeting the progression of Parkinson's disease. Current neuropharmacology, 7(1), 9-36.
Geroin, C., Gandolfi, M., Bruno, V., Smania, N., & Tinazzi, M. (2016). Integrated approach for pain management in Parkinson disease. Current neurology and neuroscience reports, 16(4), 28. DOI: https://doi.org/10.1007/s11910-016-0628-7
Gillies, G. E., Pienaar, I. S., Vohra, S., & Qamhawi, Z. (2014). Sex differences in Parkinson’s disease. Frontiers in neuroendocrinology, 35(3), 370-384. DOI: https://doi.org/10.1016/j.yfrne.2014.02.002
Granovsky, Y., Schlesinger, I., Fadel, S., Erikh, I., Sprecher, E., & Yarnitsky, D. (2013). Asymmetric pain processing in Parkinson's disease. European Journal of Neurology, 20(10), 1375-1382. DOI: https://doi.org/10.1111/ene.12188
Grover, S., Somaiya, M., Kumar, S., & Avasthi, A. (2015). Psychiatric aspects of Parkinson's disease. Journal of neurosciences in rural practice, 6(1), 65. DOI: https://dx.doi.org/10.4103%2F0976-3147.143197
Hodges, P. W. (2011). Pain and motor control: from the laboratory to rehabilitation. Journal of Electromyography and Kinesiology, 21(2), 220-228. DOI: https://doi.org/10.1016/j.jelekin.2011.01.002
Lim, S. Y., Tan, A. H., Fox, S. H., Evans, A. H., & Low, S. C. (2017). Integrating patient concerns into Parkinson’s disease management. Current neurology and neuroscience reports, 17(1), 3. DOI: https://doi.org/10.1007/s11910-017-0717-2
Mattos, D. C., Meziat Filho, N. A., Pedron, C. A., Vasconcellos, L. F., Nogueira, L. A., & de Oliveira, L. A. S. (2019). Pain Characteristics and Their Relationship With Motor Dysfunction in Individuals With Parkinson Disease—A Cross‐Sectional Study. Pain Practice, 19(7), 732-739. DOI: https://doi.org/10.1111/papr.12803
Navarro-Peternella, F. M., & Marcon, S. S. (2012). Quality of life of a person with Parkinson's disease and the relationship between the time of evolution and the severity of the disease. Revista latino-americana de enfermagem, 20(2), 384-391. DOI: https://doi.org/10.1590/S0104-11692012000200023
Pereira, A.S., Shitsuka, D. M., Parreira, F. J., Shitsuka, R. Metodologia da pesquisa científica. [eBook]. Santa Maria. Ed. UAB / NTE / UFSM. Available at: https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1.
Raza, C., & Anjum, R. (2019). Parkinson's disease: Mechanisms, translational models and management strategies. Life sciences, 226, 77-90. DOI: https://doi.org/10.1016/j.lfs.2019.03.057
Redecker, C., Bilsing, A., Csoti, I., Fogel, W., Ebersbach, G., Hauptmann, B., Hellwig, B., & Müngersdorf, M. (2014). Physiotherapy in Parkinson's disease patients: recommendations for clinical practice. Basal Ganglia, 4(1), 35-38. DOI: https://doi.org/10.1016/j.baga.2014.03.001
Reekes, T. H., Higginson, C. I., Ledbetter, C. R., Sathivadivel, N., Zweig, R. M., & Disbrow, E. A. (2020). Sex specific cognitive differences in Parkinson disease. npj Parkinson's Disease, 6(1), 1-6. DOI: https://doi.org/10.1038/s41531-020-0109-1
Regitz‐Zagrosek, V. (2012). Sex and gender differences in health: Science & Society Series on Sex and Science. EMBO reports, 13(7), 596-603. DOI: https://doi.org/10.1038/embor.2012.87
Reuter, I., Mehnert, S., Leone, P., Kaps, M., Oechsner, M., & Engelhardt, M. (2011). Effects of a flexibility and relaxation programme, walking, and nordic walking on Parkinson's disease. Journal of aging research, 2011, 232473. DOI: https://doi.org/10.4061/2011/232473
Rocca, W. A., Mielke, M. M., Vemuri, P., & Miller, V. M. (2014). Sex and gender differences in the causes of dementia: a narrative review. Maturitas, 79(2), 196-201. DOI: https://doi.org/10.1016/j.maturitas.2014.05.008
Sage, J. I. (2004). Pain in Parkinson’s disease. Current treatment options in neurology, 6(3), 191-200.
Samii, A., Nutt, J. G., & Ransom, B. R. (2004). Parkinson’s disease. The Lancet, 363(9423), 1783–1793. DOI: https://doi.org/10.1016/s0140-6736(04)16305-8
Smith, K. M., & Dahodwala, N. (2014). Sex differences in Parkinson's disease and other movement disorders. Experimental neurology, 259, 44-56. DOI: https://doi.org/10.1016/j.expneurol.2014.03.010
Taylor, K. S. M., Cook, J. A., & Counsell, C. E. (2007). Heterogeneity in male to female risk for Parkinson’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 78(8), 905-906. DOI: http://dx.doi.org/10.1136/jnnp.2006.104695
Wooten, G. F., Currie, L. J., Bovbjerg, V. E., Lee, J. K., & Patrie, J. (2004). Are men at greater risk for Parkinson’s disease than women?. Journal of Neurology, Neurosurgery & Psychiatry, 75(4), 637-639. DOI: http://dx.doi.org/10.1136/jnnp.2003.020982
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Midia Wolff Marques; Andréia Fuentes Soares; Eduarda Carolina Amaral; Vivian Francielle França; Durcelina Schiavoni Bortoloti; Evellyn Claudia Wietzikoski Lovato; Francislaine Aparecida dos Reis Lívero
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
