A cross-sectional epidemiological study reveals a strong link between tuberculosis, social vulnerability, and HIV-Tuberculosis co-infection in Central Mozambique
DOI:
https://doi.org/10.33448/rsd-v14i10.49781Keywords:
Tuberculosis, HIV co-infection, Socio-demographic factors, Epidemiological profile, Public Health.Abstract
This study aims to describe the socio-demographic characteristics of TB patients in Buzi, assess the clinical features, including TB type and HIV co-infection, and review TB control strategies in the district. Tuberculosis (TB) remains a significant public health challenge in Mozambique, especially in Búzi. This study characterized the epidemiological profile of TB patients treated in Búzi district, between 2020 and 2022. A descriptive, cross-sectional study was conducted using secondary data from patient registers at four public health units: Búzi Rural Hospital and the health centers of Bandua, Estaquinha, and Barada. The sample included all patients aged 18 or older with a confirmed TB diagnosis. Data were analyzed using SPSS version 20 to generate descriptive statistics and identify patterns of TB-HIV co-infection. A total of 1,065 TB cases were identified, with 53% of patients being female and 52.9% aged between 36 and 60 years. A significant proportion had no formal education and were either unemployed or engaged in domestic occupations. TB-HIV co-infection was found in 28.1% of cases. Treatment completion was reported in 77.8% of patients, while 2.5% died. TB-HIV co-infection was significantly associated with sex, age group, place of residence, and TB type. The study highlights the strong association between TB, social vulnerability, and HIV co-infection in Búzi. Strengthening access to diagnostics, expanding treatment coverage, and implementing integrated care strategies are essential to improving outcomes in similar rural contexts.
References
Barreto, R. M., & Garcia, M. F. (2021). Tuberculose em Moçambique: uma análise epidemiológica crítica. Revista de Saúde Pública, 55(3), 202–10.
Berquó, E. S., Sousa, J. M. P., Gotlieb, S. L. D. ( 1981). Bioestatística. Editora EPU.
Chissaque, A., Nhacolo, A., & Sitoe, N. (2021). Determinants of tuberculosis in central Mozambique: A community-based study. Mozambican Medical Journal. 5(2), 35–42.
Coelho, L. E., Escada, R. O. S., Barbosa, H. P. P., Santos, V. G. V., Grinszjn, B. G. J. (2016). O tratamento da coinfecção HIV-TB. https://www.bjid.org.br/en-pdf-X2177511716600168.
Cravo, J., Marques, M. A. T. (2018). Tuberculosis and Gender Factors Inflencing the Risk among Men and Women Age Group. Sociedade Portuguesa de Pneumologia. Editora Elsevier Espana.
Faria, F. P., & Lopes, J. T. (2020). Epidemiological trends of tuberculosis and co-infection with HIV in rural Mozambique. Journal of Global Health Reports, 4, e2020046.
IFRC (International Federation of Red Cross and Red Crescent Societies). (2019). Mozambique: Cyclone Idai Emergency Appeal Update.
MISAU (Ministério da Saúde). (2019). Manual para o Manejo da Tuverculose na Criança, Adolescente e na Mulher Grávida. https://www.misau.gov.mz/index.php/manuais-directrizes-e-guioes-tb? download=271:manual-para-o-manejo-da-tuberculose-na-crianca-no-adolescente-e-na-mulher-gravida.
MISAU (Ministério da Saúde). (2022). Relatório Anual de Desempenho do Programa Nacional de Controlo da Tuberculose.
Narasimhan, P., Wood, J. MacIntyre, C. R., Mathai, D. (2013). Risk Factors for Tuberculosis. https://onlinelibrary.wiley.com/doi/epdf/10.1155/2013/828939.
Órfão, A. C.N. (2017). Tuberculose Multirresstente – a realidade actual. https://repositorio.ul.pt/bitstream/10451/30752/1/AnaCNOrfao.pdf.
Pereira, A. S. et al. (2018). Metodologia da pesquisa científica. [free ebook]. Santa Maria: Editora da UFSM.
Pires, G. M. (2021). Análise das políticas de controlo da tuberculose e do perfil epidemiológico da infecção em Moçambique (2009-2017). https://run.unl.pt/bitstream/10362/118343/1/TESE%20DEFINITIVA_Germano_Manuel_Pires_22-04-2021.pdf.
PNCT (Programa Nacional de Controlo da Tuberculose). (2022). Boletim Epidemiológico Nacional 2020–2021.
Rieder, H. L. (2001). Bases epidemiológicas do controle da tuberculose. Lisboa: Direção Geral da Saúde.
Sá, A. M. M., Santiago, L. A., Santos, N. V., Monteiro, N. P., Pinto, P. H. A., Lima, A. M., Iwasaka-Neder, P. L. (2017). Causas de abandono do tratamento entre portadores de tuberculose. https://docs.bvsalud.org/biblioref/2017/11/875434/sbcm_153_155-160.pdf.
SDSMAS-Búzi. (2022). Boletim Estatístico Distrital de Saúde, 2021–2022.
Shitsuka, R. et al. (2014). Matemática fundamental para a tecnologia. (2ed). Editora Érica.
Torcida, P. C. I. (2021). Aspectos epidemiológicos da tuberculose e dos serviços de atendimento à pessoa com tuberculose no Município de Chimoio, Moçambique, 2018-2019. https://www.teses.usp.br/teses/disponiveis/6/6143/tde-06012022-204237/publico/TorcidaPCI_MTR_R.pdf.
WHO. (2019). Global Tuberculosis Report 2019. Geneva: World Health Organization.
WHO. (2020). Global Tuberculosis Report 2020. Geneva: World Health Organization.
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