Adhesion to healthy and caries-affected dentin: A comparative analysis
DOI:
https://doi.org/10.33448/rsd-v14i11.50021Keywords:
Bonding, Healthy, Dentin, Endurance, Affected, Caries.Abstract
Objective: To analyze and compare, through a literature review, the performance of adhesive systems on sound and caries-affected dentin, identifying the main factors that influence the quality and longevity of the bond on each substrate. Methodology: A narrative review was conducted based on publications indexed in Google Scholar, SciELO, PubMed, and Cochrane. Articles published in Portuguese and English in the last fifteen years that compared the adhesive performance between sound and caries-affected dentin were included. Results and discussion: The literature shows that the structural properties of dentin directly influence the efficiency of adhesive systems. In general, conventional etch-and-rinse adhesives and universal adhesives applied in the same way have demonstrated better performance on caries-affected dentin. However, the adhesive interface on this substrate is more vulnerable to hydrolytic degradation and the action of metalloproteinases (MMPs), which compromises the stability of the hybrid layer. The lack of effective chemical bonding between the adhesive and exposed collagen remains a limiting factor for the longevity of restorations. New research has emphasized the importance of strategies focused on enzyme inhibition and the use of bioinspired monomers capable of chemically interacting with collagen, promoting more durable interfaces. Conclusion: Selecting the adhesive strategy based on the conditions of the dentin substrate has considerable potential to transform restorative practice, promoting more durable and stable treatments.
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Copyright (c) 2025 Ana Clara Portela Novais, Bruno Emanuel Portela Almeida, Giullia Dias Santana, Ian Matos Vieira, Ana Flávia Soares

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