Risk factors for hyperglycemia in kidney transplant patients
DOI:
https://doi.org/10.33448/rsd-v9i2.2143Keywords:
Kidney transplantation; Nutritional status; Blood glucose; Nutritional assessment;Abstract
The aim of this study was to analyze the risk factors associated with hyperglycemia in renal transplant patients. For this, a retrospective cross-sectional study was conducted to collect clinical, laboratory and anthropometric data from patients who underwent kidney transplantation. To identify factors associated with hyperglycemia, a bivariate and multivariate analysis was performed with hierarchical models. Among the 89 patients evaluated, the body mass index revealed 47.1% of eutrophic patients and 34.7% overweight. 28% of the patients had hyperglycemia and 82%, 86.5%, 87.6% and 91% had altered creatinine, urea, hemoglobin, and hematocrit, respectively. A statistically significant association (p <0.05) of hyperglycemia with obesity II and III was found, and patients with obesity II and III were more likely to have altered glycemia and potassium, (PR = 4.91; CI: 1.04, p <0.001; RP = 2.23; CI: 1.09-4.54, p = 0.026), respectively. Obesity and hyperkalemia were found to be risk factors for hyperglycemia in renal transplant patients.
References
Aksoy, N. (2016). Weight gain after kideney transplant. Exp Clin Transplant. 14(Suppl 3):138-140.
Associação Brasileira de Transplante de Órgãos (ABTO). (2018). Registro Brasileiro de Transplantes. Dimensionamento dos Transplantes no Brasil e em cada Estado. Ano XXIV, n.4.
Associação Brasileira para o Estudo da Obesidade e da Síndrome Metabólica - ABESO. (2016). Diretrizes Brasileiras de Obesidade. 4ª Ed. São Paulo: ABESO.
Blackburn, G. L., Thornton, P. A. (1979). Nutritional assessment of the hospitalized patient. Med Clin North Am. 63(5):11103-15.
Brasil. (2011). Ministério da Saúde. Orientações para a coleta e análise de dados antropométricos em serviços de saúde: Norma Técnica do Sistema de Vigilância Alimentar e Nutricional – SISVAN. Brasília, Ministério da Saúde.
Calixto-Lima, L., Gonzales, M. C. (2018). Nutrição Clínica no dia a dia. 2ª ed. Rio de Janeiro: Rubio.
Claudino, L. M., de Souza, T. F., Mezzomo, T. R. (2018). Relação entre eficiência da hemodiálise e estado nutricional em pacientes com doença renal crônica. Sci Med. 28(3):ID31674.
Conte, C., Secchi, A. (2018). Post-transplantation diabetes in kidney transplant recipients: an update on management and prevention. Acta Diabetol. 55(8):763-779.
Frisancho, A. R. (1981). New norms of upper limb fat and muscle areas for assessment of nutritional status. Am J Clin Nutr. 34:2540-2545.
Ghanta, M., Kozicky, M., Jim, B. (2015). Pathophysiologic and treatment strategies for cardiovascular disease in end-stage renal disease and kidney transplantations. Cardiol Rev. 23(3):109-18.
Guthoff, M., Wagner, R., Weichbrodt, K., Nadalin, S., Königsrainer, A., Häring, H. U., et al. (2017). Dynamics of glucose metabolism after kidney transplantation. Kidney Blood Press Res.42(3):598–607.
Henge, A. E., Montaurier, C., Cano, N., Caillot, N., Blot, A., Meunier, N., et al. (2015). Energy expenditure, spontaneous physical activity and with weight gain in kidney transplant recipients. Clin Nutr. 34(3):457-64.
Kim, I. K., Choi, S. H., Son, S., Ju, M. K. (2016). Early weight gain after transplantation can cause adverse effect on transplant kidney function. Transplant Proc. 48(3):893-6.
Lienert, R. S. C., Figueiredo, C. E. P., Figueiredo, A. E. P. L. (2014). Evolução do peso durante o primeiro ano de transplante renal e a ocorrência de Diabetes Mellitus após 5 anos de segmento. Ciência&Saúde. 7(3):148-154.
Liese, J., Bottner, N., Büttner, S., Reinisch, A., Woeste, G., Wortmann, M., et al. (2018). Influence of the recipient body mass index on the outcomes after kidney transplantation. Langenbecks Arch Surg. 403(1):73-82.
Liu, J. Y., You, R. X., Guo, M., Zeng, L., Zhou, P., Zhu, L., et al. (2016). Tacrolimus Versus Cyclosporine as Primary Immunosuppressant After Renal Transplantation: A Meta-Analysis and Economics Evaluation. Am J Ther. 23(3):e810-24.
Mazzali, F., Lalli, A., Alves-Filho, G., Mazzali, M. (2008). Posttransplant Diabetes Mellitus: incidence and risk factors. Transplant Proc. 40(3):764-6.
Pereira, F. E. F., Monteiro, H. M. C., Tomiya, M. T. O. (2016). Perfil nutricional de pacientes transplantados renais atendidos no ambulatório de nutrição de um hospital de Recife-PE. Rev Bras Nutr Clin. 31(1):29-33.
Rezende, L. R., Souza, P. B., Pereira, G. R. M., Lugon, J. R. (2017). Acidose metabólica em pacientes em hemodiálise: uma revisão. J Bras Nefrol. 39(3):305-311.
Tadano, Y., S., Ugaya, C., M., L., Franco, A., T. Método de regressão de Poisson: metodologia para avaliação do impacto da poluição atmosférica na saúde populacional. (2009). Ambiente & Sociedade. 7(2):241-255.
Thuret, R., Timsit, M. O., Kleinclauss, F. (2016). Chronic kidney disease and kidney transplantation. Prog Urol. 26(15):882-908.
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