Probióticos: Um guia prático de prescrição personalizada

Filipa Lino e Ribeiro; Ana Ascenso; Joana Landeiro; João V. Miranda; Sara Crespo; Rui Pinto

doi:10.33448/rsd-v14i11.50174

Autores

Filipa Lino e Ribeiro Escola de Medicina Tradicional Chinesa https://orcid.org/0009-0004-5081-2231
Ana Ascenso Escola de Medicina Tradicional Chinesa https://orcid.org/0009-0003-1417-735X
Joana Landeiro Escola de Medicina Tradicional Chinesa https://orcid.org/0009-0005-1192-5089
João V. Miranda Escola de Medicina Tradicional Chinesa https://orcid.org/0009-0007-8678-3665
Sara Crespo Escola de Medicina Tradicional Chinesa https://orcid.org/0009-0003-6617-4337
Rui Pinto Escola de Medicina Tradicional Chinesa https://orcid.org/0000-0003-2923-5041

DOI:

https://doi.org/10.33448/rsd-v14i11.50174

Palavras-chave:

Probióticos, Prebióticos, Patologia clínica, Composição de medicamentos, Posologia.

Resumo

Este estudo teve como objetivo propor um guia prático de prescrição personalizada de probióticos e prebióticos manipulados, com base em evidência científica, relacionando cepas específicas, patologias e dosagens eficazes. Realizou-se uma revisão narrativa com abordagem integrativa, com busca em bases científicas (PubMed, Scopus, Embase) e documentos técnicos de referência (OMS, FAO, EFSA), entre 2010 e 2025. Foram incluídos ensaios clínicos, revisões sistemáticas e consensos técnicos. Selecionaram-se 24 cepas probióticas e 6 prebióticos com uso clínico documentado. Os dados foram organizados numa tabela-síntese que relaciona patologias específicas com as cepas e prebióticos indicados e respetivas dosagens eficazes (Quadro 1). Destacam-se: Lactobacillus plantarum e Bifidobacterium infantis para doenças gastrointestinais; B. lactis e L. gasseri em síndromes metabólicas; L. helveticus e B. breve em distúrbios emocionais; P. freudenreichii em doenças inflamatórias; L. crispatus para saúde ginecológica; e B. breve e E. faecium na pediatria. As dosagens variaram entre 1×10⁸ e 1×10¹⁰ UFC/dia, de acordo com a condição clínica e a cepa. A prescrição simbiótica manipulada e personalizada, fundamentada na correlação entre patologia, cepa e dose, representa uma abordagem promissora na medicina integrativa, contribuindo para intervenções clínicas mais eficazes, seguras e baseadas em evidência.

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